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ONTOLOGY REPORT - ANNOTATIONS

Term:autophagy of mitochondrion
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Accession:GO:0000422 term browser browse the term
Definition:The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
Synonyms:broad_synonym: mitochondrion degradation;   mitochondrion disassembly
 related_synonym: mitophagy


show annotations for term's descendants           Sort by:
autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647 		JBrowse link
G Atg2a autophagy related 2A involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:6,291,508...6,312,332
Ensembl chr19:6,291,698...6,312,365 		JBrowse link
G Atg2b autophagy related 2B involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:105,579,798...105,651,554
Ensembl chr12:105,582,395...105,651,470 		JBrowse link
G Atg3 autophagy related 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:44,979,192...45,008,901
Ensembl chr16:44,979,148...45,008,901 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within IMP (PMID:23981124) MGI PMID:23981124 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Capn10 calpain 10 ISO RGD PMID:22568896 RGD:7247732 NCBI chr 1:92,862,130...92,875,670
Ensembl chr 1:92,862,098...92,875,663 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 involved_in IBA
IMP		 (PMID:19451219) GO_Central
UniProt		 PMID:19451219 GO_REF:0000033 NCBI chr 3:135,112,173...135,129,194
Ensembl chr 3:135,112,173...135,129,686 		JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 acts_upstream_of_or_within ISO
IMP		 (PMID:32525278) MGI PMID:32525278 NCBI chr 4:22,357,526...22,434,091
Ensembl chr 4:22,357,543...22,434,091 		JBrowse link
G Fbxo7 F-box protein 7 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Fundc1 FUN14 domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000008 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr  X:17,386,206...17,438,600
Ensembl chr  X:17,422,803...17,438,564 		JBrowse link
G Fundc2 FUN14 domain containing 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:74,426,005...74,440,764
Ensembl chr  X:74,426,005...74,440,065 		JBrowse link
G Fundc2b FUN14 domain containing 2B involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:40,854,631...40,856,936
Ensembl chr 3:40,854,631...40,856,978 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISS
IBA
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ISO RGD PMID:19783904 RGD:10059673 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS		 GO_Central
ParkinsonsUK-UCL
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:6,284,858...6,346,599
Ensembl chr 1:6,276,421...6,346,872 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 acts_upstream_of_or_within IMP (PMID:28934388) MGI PMID:28934388 NCBI chr18:31,713,217...31,743,585
Ensembl chr18:31,689,164...31,742,964 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:114,238,395...114,261,571
Ensembl chr 5:114,203,522...114,262,781 		JBrowse link
G Wdr45 WD repeat domain 45 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:7,588,212...7,594,439
Ensembl chr  X:7,580,572...7,594,445 		JBrowse link
G Wdr45b WD repeat domain 45B involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:121,218,029...121,246,393
Ensembl chr11:121,218,050...121,245,271 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793 		JBrowse link
G Wipi2 WD repeat domain, phosphoinositide interacting 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:142,615,269...142,655,427
Ensembl chr 5:142,613,453...142,656,343 		JBrowse link
mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl interactor 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:60,444,927...60,521,104
Ensembl chr 1:60,448,778...60,520,317 		JBrowse link
G Ambra1 autophagy/beclin 1 regulator 1 involved_in IBA
IEA
ISO		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194 		JBrowse link
G Arfip2 ARF interacting protein 2 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:105,283,408...105,289,623
Ensembl chr 7:105,283,410...105,289,623 		JBrowse link
G Arhgap26 Rho GTPase activating protein 26 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:38,734,531...39,509,338
Ensembl chr18:39,126,198...39,509,337
Ensembl chr18:39,126,198...39,509,337 		JBrowse link
G Atg10 autophagy related 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:91,083,467...91,372,189
Ensembl chr13:91,083,475...91,372,087 		JBrowse link
G Atg13 autophagy related 13 involved_in IBA
IMP		 (PMID:21855797) GO_Central
ParkinsonsUK-UCL		 PMID:21855797 GO_REF:0000033 NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921 		JBrowse link
G Atg14 autophagy related 14 involved_in IBA
ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106 		JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:139,854,594...139,947,190
Ensembl chr  X:139,857,656...139,947,266 		JBrowse link
G Atg4a-ps autophagy related 4A, pseudogene involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:103,551,269...103,553,384
Ensembl chr 3:103,551,270...103,553,384 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase involved_in IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:93,682,627...93,717,328
Ensembl chr 1:93,679,222...93,718,332 		JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:99,077,181...99,185,495
Ensembl chr 4:99,082,171...99,148,024 		JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase involved_in IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 9:21,176,496...21,186,133
Ensembl chr 9:21,176,589...21,189,068 		JBrowse link
G Atg5 autophagy related 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atg7 autophagy related 7 involved_in IMP
IBA
ISO		 (PMID:20080761) ParkinsonsUK-UCL
GO_Central		 PMID:20080761 GO_REF:0000033 GO_REF:0000119 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Atg9a autophagy related 9A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:75,157,509...75,168,654
Ensembl chr 1:75,157,504...75,168,840 		JBrowse link
G Atg9b autophagy related 9B involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:24,589,179...24,597,141
Ensembl chr 5:24,589,179...24,597,141 		JBrowse link
G Bcl2l13 BCL2 like 13 acts_upstream_of_or_within IMP (PMID:31266807) MGI PMID:31266807 NCBI chr 6:120,813,167...120,869,803
Ensembl chr 6:120,813,173...120,869,803 		JBrowse link
G Becn1 beclin 1, autophagy related involved_in ISO
IBA		 GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Becn2 beclin 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:175,747,895...175,749,791
Ensembl chr 1:175,747,895...175,749,791 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Clec16a C-type lectin domain family 16, member A involved_in ISO (PMID:35604110) DisProt PMID:35604110 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Ctsk cathepsin K involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784 		JBrowse link
G Fundc1 FUN14 domain containing 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:17,386,206...17,438,600
Ensembl chr  X:17,422,803...17,438,564 		JBrowse link
G Gabarap gamma-aminobutyric acid receptor associated protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:69,882,196...69,885,775
Ensembl chr11:69,881,969...69,885,777 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:129,510,155...129,519,294
Ensembl chr 6:129,510,123...129,519,309 		JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:112,667,335...112,679,547
Ensembl chr 8:112,667,335...112,680,244 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within IMP (PMID:23707074) MGI PMID:23707074 NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273 		JBrowse link
G Lrba LPS-responsive beige-like anchor involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 3:86,130,763...86,690,001
Ensembl chr 3:86,131,987...86,689,999 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499 		JBrowse link
G Nipsnap1 nipsnap homolog 1 involved_in IDA
ISO		 (PMID:30982665) UniProt
GO_Central		 PMID:30982665 GO_REF:0000119 NCBI chr11:4,823,951...4,844,201
Ensembl chr11:4,823,951...4,844,200 		JBrowse link
G Nipsnap2 nipsnap homolog 2 involved_in IDA
ISO		 (PMID:30982665) UniProt
GO_Central		 PMID:30982665 GO_REF:0000119 NCBI chr 5:129,802,080...129,835,391
Ensembl chr 5:129,802,127...129,835,391 		JBrowse link
G Nipsnap3b nipsnap homolog 3B involved_in IEA UniProt GO_REF:0000117 NCBI chr 4:53,011,932...53,022,060
Ensembl chr 4:53,011,880...53,022,060 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) involved_in IMP (PMID:33406421) ARUK-UCL PMID:33406421 NCBI chr  X:100,683,617...100,727,957
Ensembl chr  X:100,683,666...100,727,957 		JBrowse link
G Phb2 prohibitin 2 involved_in IDA
ISO		 (PMID:28017329) UniProt
GO_Central		 PMID:28017329 GO_REF:0000119 NCBI chr 6:124,689,252...124,693,908
Ensembl chr 6:124,689,299...124,693,913 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO
IEA		 GO_Central
Ensembl
RGD		 PMID:25154397 GO_REF:0000107 GO_REF:0000119 RGD:12904014 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 IGI
IBA
ISO		 (PMID:24949970) MGI
GO_Central		 PMID:24949970 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Retreg1 reticulophagy regulator 1 acts_upstream_of_or_within IDA (PMID:31446166) MGI PMID:31446166 NCBI chr15:25,840,795...25,973,782
Ensembl chr15:25,843,266...25,973,773 		JBrowse link
G Rimoc1 RAB7A interacting MON1-CCZ1 complex subunit 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr15:4,011,517...4,025,228
Ensembl chr15:4,011,517...4,025,226 		JBrowse link
G Snx30 sorting nexin family member 30 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:59,805,137...59,904,740
Ensembl chr 4:59,805,840...59,904,737 		JBrowse link
G Snx7 sorting nexin 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:117,575,146...117,662,585
Ensembl chr 3:117,575,296...117,662,585 		JBrowse link
G Spata33 spermatogenesis associated 33 involved_in IMP (PMID:33087875) UniProt PMID:33087875 NCBI chr 8:123,939,572...123,948,784
Ensembl chr 8:123,939,571...123,948,785 		JBrowse link
G Sqstm1 sequestosome 1 involved_in IBA
IEA
ISO		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in IMP
ISO		 (PMID:25919711) UniProt
GO_Central		 PMID:25919711 GO_REF:0000119 NCBI chr  X:73,325,498...73,340,182
Ensembl chr  X:73,325,518...73,333,757 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of IMP (PMID:22044588) MGI PMID:22044588 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of IMP (PMID:22044588) MGI PMID:22044588 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Ulk1 unc-51 like kinase 1 involved_in IMP
IBA		 (PMID:21855797) ParkinsonsUK-UCL
GO_Central		 PMID:21855797 GO_REF:0000033 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
G Ulk2 unc-51 like kinase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:61,666,424...61,750,754
Ensembl chr11:61,666,475...61,745,899 		JBrowse link
G Ulk3 unc-51-like kinase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:57,496,423...57,503,516
Ensembl chr 9:57,496,735...57,503,516 		JBrowse link
mitophagy by internal vacuole formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spata18 spermatogenesis associated 18 involved_in IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:73,808,723...73,836,927
Ensembl chr 5:73,808,722...73,836,855 		JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain family 16, member A acts_upstream_of_or_within IMP (PMID:24949970) MGI PMID:24949970 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within IGI (PMID:24949970) MGI PMID:24949970 NCBI chr10:128,247,485...128,277,310
Ensembl chr10:128,247,526...128,277,310 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IMP (PMID:22044588) MGI PMID:22044588 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within IMP (PMID:22044588) MGI PMID:22044588 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tspo translocator protein involved_in IMP (PMID:25470454) ParkinsonsUK-UCL PMID:25470454 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 involved_in ISO
IEA		 RGD
Ensembl
GO_Central		 PMID:24896179 GO_REF:0000096 GO_REF:0000107 RGD:13208875 NCBI chr 5:114,238,395...114,261,571
Ensembl chr 5:114,203,522...114,262,781 		JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in IMP (PMID:24709290) ParkinsonsUK-UCL PMID:24709290 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254 		JBrowse link
G Vps13c vacuolar protein sorting 13C involved_in ISO
ISS		 GO_Central
ParkinsonsUK-UCL		 GO_REF:0000024 GO_REF:0000119 NCBI chr 9:67,747,594...67,905,026
Ensembl chr 9:67,747,678...67,902,920 		JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2/adenovirus E1B interacting protein 3 involved_in ISO
IEA		 RGD
Ensembl
GO_Central		 PMID:23698117 GO_REF:0000096 GO_REF:0000107 RGD:11561968 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Fbxo7 F-box protein 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy/beclin 1 regulator 1 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194 		JBrowse link
G Atg7 autophagy related 7 ISO RGD PMID:37042059 RGD:407532700 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 8:70,768,425...70,784,238
Ensembl chr 8:70,768,425...70,784,242 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:38,383,302...38,395,682
Ensembl chr18:38,383,308...38,398,514 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:143,803,586...143,839,535
Ensembl chr 5:143,803,543...143,841,069 		JBrowse link
G Fbxo7 F-box protein 7 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Htt huntingtin involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Igtp interferon gamma induced GTPase involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in ISO
IMP		 (PMID:33510463) GO_Central
UniProt		 PMID:33510463 GO_REF:0000119 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in IMP (PMID:31919280) UniProt PMID:31919280 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO RGD
GO_Central		 PMID:28608965 GO_REF:0000096 GO_REF:0000119 RGD:13432560 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 involved_in IDA (PMID:31618756) UniProt PMID:31618756 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321 		JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 involved_in IDA (PMID:31618756) UniProt PMID:31618756 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460 		JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378 		JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in IMP
ISO		 (PMID:23685073) UniProt
GO_Central		 PMID:23685073 GO_REF:0000119 NCBI chr  X:36,137,948...36,147,875
Ensembl chr  X:36,064,828...36,147,875 		JBrowse link
G Vps13d vacuolar protein sorting 13D involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:144,597,619...144,921,598
Ensembl chr 4:144,699,192...144,921,575 		JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
G Cdc37 cell division cycle 37 involved_in IDA (PMID:21855797) ParkinsonsUK-UCL PMID:21855797 NCBI chr 9:21,050,727...21,061,230
Ensembl chr 9:21,044,518...21,061,278 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within IMP (PMID:23707074) ARUK-UCL PMID:23707074 NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in IGI (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Hk2 hexokinase 2 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435 		JBrowse link
G Huwe1 HECT, UBA and WWE domain containing 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr  X:150,583,779...150,718,413
Ensembl chr  X:150,583,803...150,718,413 		JBrowse link
G Mul1 mitochondrial ubiquitin ligase activator of NFKB 1 involved_in IMP (PMID:24709290) ParkinsonsUK-UCL PMID:24709290 NCBI chr 4:138,160,239...138,169,576
Ensembl chr 4:138,161,982...138,169,576 		JBrowse link
G Pink1 PTEN induced putative kinase 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:24,043,942...24,049,143
Ensembl chr 5:24,043,942...24,049,159 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl
GO_Central		 PMID:31172217 GO_REF:0000096 GO_REF:0000107 RGD:329403053 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like involved_in IGI (PMID:20200478) ParkinsonsUK-UCL PMID:20200478 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326 		JBrowse link
G Csnk2a2 casein kinase 2, alpha prime polypeptide involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 8:96,172,724...96,215,505
Ensembl chr 8:96,172,724...96,216,667 		JBrowse link
G Cttn cortactin involved_in IMP (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr 7:143,989,468...144,024,743
Ensembl chr 7:143,989,470...144,024,746 		JBrowse link
G Dnm1l dynamin 1-like involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505 		JBrowse link
G Fkbp8 FK506 binding protein 8 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 8:70,980,371...70,987,978
Ensembl chr 8:70,980,374...70,987,978 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in IMP (PMID:21355049) ParkinsonsUK-UCL PMID:21355049 NCBI chr16:20,098,570...20,121,090
Ensembl chr16:20,098,568...20,121,137 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Srebf2 sterol regulatory element binding factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in IMP (PMID:25470454) ParkinsonsUK-UCL PMID:25470454 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Mfn2 mitofusin 2 involved_in IMP (PMID:23620051) ParkinsonsUK-UCL PMID:23620051 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Optn optineurin involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:5,023,902...5,069,210
Ensembl chr 2:5,025,453...5,068,862 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IMP (PMID:22020285) ParkinsonsUK-UCL PMID:22020285 NCBI chr 5:144,813,305...144,902,657
Ensembl chr 5:144,813,305...144,902,657 		JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:31,902,123...31,923,848
Ensembl chr14:31,902,119...31,923,855 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      process utilizing autophagic mechanism 560
        autophagy 560
          autophagy of mitochondrion 113
            micromitophagy 0
            mitophagy + 94
            mitophagy by internal vacuole formation 1
            negative regulation of autophagy of mitochondrion + 9
            positive regulation of autophagy of mitochondrion + 28
            regulation of autophagy of mitochondrion + 49
Path 2
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      metabolic process 11662
        catabolic process 2901
          autophagy 560
            autophagy of mitochondrion 113
              micromitophagy 0
              mitophagy + 94
              mitophagy by internal vacuole formation 1
              negative regulation of autophagy of mitochondrion + 9
              positive regulation of autophagy of mitochondrion + 28
              regulation of autophagy of mitochondrion + 49
paths to the root