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ONTOLOGY REPORT - ANNOTATIONS

Term:autophagy of mitochondrion
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Accession:GO:0000422 term browser browse the term
Definition:The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
Synonyms:broad_synonym: mitochondrion degradation;   mitochondrion disassembly
 related_synonym: mitophagy


show annotations for term's descendants           Sort by:
autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG12 autophagy related 12 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837 		JBrowse link
G ATG2A autophagy related 2A involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:64,894,546...64,917,209
Ensembl chr11:64,894,546...64,917,209 		JBrowse link
G ATG2B autophagy related 2B involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:96,279,195...96,363,341
Ensembl chr14:96,279,195...96,363,341 		JBrowse link
G ATG3 autophagy related 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:23981124) MGI PMID:23981124 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in NAS (PMID:22505714) ParkinsonsUK-UCL PMID:22505714 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G CAPN10 calpain 10 ISO RGD PMID:22568896 RGD:7247732 NCBI chr 2:240,586,734...240,599,104
Ensembl chr 2:240,586,734...240,617,705 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in IMP (PMID:25217637) ParkinsonsUK-UCL PMID:25217637 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CISD2 CDGSH iron sulfur domain 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:102,868,992...102,892,807
Ensembl chr 4:102,868,974...102,892,807 		JBrowse link
G FBXL4 F-box and leucine rich repeat protein 4 acts_upstream_of_or_within
involved_in		 IMP
IEA		 (PMID:32525278) MGI
Ensembl		 PMID:32525278 GO_REF:0000107 NCBI chr 6:98,868,535...98,947,946
Ensembl chr 6:98,868,535...98,948,006 		JBrowse link
G FBXO7 F-box protein 7 involved_in IMP (PMID:23933751) UniProt PMID:23933751 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829 		JBrowse link
G FUNDC1 FUN14 domain containing 1 involved_in
acts_upstream_of_or_within		 IDA
IBA
IMP
IGI		 (PMID:22267086) UniProt
GO_Central
MGI		 PMID:22267086 GO_REF:0000033 NCBI chr  X:44,523,639...44,542,859
Ensembl chr  X:44,523,639...44,542,859 		JBrowse link
G FUNDC2 FUN14 domain containing 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:155,026,844...155,060,304
Ensembl chr  X:155,025,980...155,060,304 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha acts_upstream_of_or_within IGI (PMID:22267086) MGI PMID:22267086 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MARK2 microtubule affinity regulating kinase 2 involved_in NAS (PMID:24522549) ParkinsonsUK-UCL PMID:24522549 NCBI chr11:63,839,110...63,911,020
Ensembl chr11:63,838,928...63,911,020 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP
IBA		 (PMID:20798600), (PMID:23933751), (PMID:24896179) UniProt
GO_Central		 PMID:20798600 PMID:23933751 PMID:24896179 GO_REF:0000033 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:19783904 RGD:10059673 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IDA
IMP		 (PMID:25621951)
(PMID:19029340), (PMID:23933751), (PMID:24896179)		 UniProt PMID:19029340 PMID:23933751 PMID:24896179 PMID:25621951 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:52,622,458...52,714,435
Ensembl chr 8:52,622,458...52,745,843 		JBrowse link
G SLC25A46 solute carrier family 25 member 46 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28934388) MGI
Ensembl		 PMID:28934388 GO_REF:0000107 NCBI chr 5:110,738,145...110,765,157
Ensembl chr 5:110,738,136...110,765,161 		JBrowse link
G SQSTM1 sequestosome 1 involved_in NAS (PMID:20098416) ParkinsonsUK-UCL PMID:20098416 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G USP30 ubiquitin specific peptidase 30 involved_in IMP
IDA		 (PMID:24896179)
(PMID:25621951)		 UniProt PMID:24896179 PMID:25621951 NCBI chr12:109,023,089...109,088,023
Ensembl chr12:109,023,089...109,088,023 		JBrowse link
G WDR45 WD repeat domain 45 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:49,074,442...49,101,178
Ensembl chr  X:49,074,433...49,101,170 		JBrowse link
G WDR45B WD repeat domain 45B involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:82,614,562...82,648,444
Ensembl chr17:82,614,562...82,648,553 		JBrowse link
G WIPI1 WD repeat domain, phosphoinositide interacting 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:68,421,281...68,457,496
Ensembl chr17:68,420,948...68,457,513 		JBrowse link
G WIPI2 WD repeat domain, phosphoinositide interacting 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:5,190,233...5,233,855
Ensembl chr 7:5,190,196...5,233,840 		JBrowse link
mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in IDA (PMID:38081847) UniProt PMID:38081847 NCBI chr 2:203,328,394...203,432,169
Ensembl chr 2:203,328,280...203,447,728 		JBrowse link
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IDA
IBA
IGI
IMP		 (PMID:21753002)
(PMID:25215947)		 ParkinsonsUK-UCL
GO_Central		 PMID:21753002 PMID:25215947 GO_REF:0000033 NCBI chr11:46,396,412...46,594,023
Ensembl chr11:46,396,414...46,594,125 		JBrowse link
G ARFIP2 ARF interacting protein 2 involved_in IMP (PMID:33773106) UniProt PMID:33773106 NCBI chr11:6,476,519...6,481,331
Ensembl chr11:6,474,683...6,481,479 		JBrowse link
G ARHGAP26 Rho GTPase activating protein 26 involved_in IDA (PMID:38081847) UniProt PMID:38081847 NCBI chr 5:142,770,377...143,229,011
Ensembl chr 5:142,770,377...143,229,011 		JBrowse link
G ATG10 autophagy related 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:81,972,023...82,256,133
Ensembl chr 5:81,972,023...82,276,857 		JBrowse link
G ATG13 autophagy related 13 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818 		JBrowse link
G ATG14 autophagy related 14 involved_in IMP
IBA		 (PMID:23878393) ParkinsonsUK-UCL
GO_Central		 PMID:23878393 GO_REF:0000033 NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830 		JBrowse link
G ATG4A autophagy related 4A cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:108,088,829...108,154,671
Ensembl chr  X:108,091,668...108,154,671 		JBrowse link
G ATG4B autophagy related 4B cysteine peptidase involved_in IMP
IBA		 (PMID:33773106) UniProt
GO_Central		 PMID:33773106 GO_REF:0000033 NCBI chr 2:241,637,693...241,673,857
Ensembl chr 2:241,637,213...241,673,857 		JBrowse link
G ATG4C autophagy related 4C cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:62,784,132...62,865,516
Ensembl chr 1:62,784,132...62,865,516 		JBrowse link
G ATG4D autophagy related 4D cysteine peptidase involved_in IMP
IBA		 (PMID:33773106) UniProt
GO_Central		 PMID:33773106 GO_REF:0000033 NCBI chr19:10,543,904...10,553,418
Ensembl chr19:10,543,895...10,553,418 		JBrowse link
G ATG5 autophagy related 5 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G ATG7 autophagy related 7 involved_in IGI (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATG9A autophagy related 9A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717 		JBrowse link
G ATG9B autophagy related 9B involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:151,012,209...151,024,499
Ensembl chr 7:151,012,209...151,024,499 		JBrowse link
G BCL2L13 BCL2 like 13 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:31266807) MGI
Ensembl		 PMID:31266807 GO_REF:0000107 NCBI chr22:17,628,877...17,730,855
Ensembl chr22:17,628,855...17,730,855 		JBrowse link
G BECN1 beclin 1 involved_in IMP
IBA
IEA		 (PMID:23878393), (PMID:25215947) ParkinsonsUK-UCL
GO_Central
Ensembl		 PMID:23878393 PMID:25215947 GO_REF:0000033 GO_REF:0000107 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BECN2 beclin 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:241,957,767...241,959,062
Ensembl chr 1:241,957,767...241,959,062 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IMP (PMID:22505714) FlyBase PMID:22505714 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G CLEC16A C-type lectin domain containing 16A involved_in IDA (PMID:35604110) DisProt PMID:35604110 NCBI chr16:10,944,564...11,182,186
Ensembl chr16:10,944,539...11,182,186 		JBrowse link
G CTSK cathepsin K involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha involved_in IDA (PMID:38340717) UniProt PMID:38340717 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G FUNDC1 FUN14 domain containing 1 involved_in IGI (PMID:34244144) FlyBase PMID:34244144 NCBI chr  X:44,523,639...44,542,859
Ensembl chr  X:44,523,639...44,542,859 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:7,240,008...7,242,449
Ensembl chr17:7,240,008...7,242,449 		JBrowse link
G GABARAPL1 GABA type A receptor associated protein like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,212,877...10,223,128
Ensembl chr12:10,212,458...10,223,128 		JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:75,566,379...75,577,881
Ensembl chr16:75,566,375...75,577,881 		JBrowse link
G GABARAPL3 GABA type A receptor associated protein like 3 (pseudogene) involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:90,346,527...90,349,447
Ensembl chr15:90,348,844...90,349,197 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23707074) Ensembl
MGI		 PMID:23707074 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G LRBA LPS responsive beige-like anchor protein involved_in IMP (PMID:33773106) UniProt PMID:33773106 NCBI chr 4:150,264,435...151,015,727
Ensembl chr 4:150,264,435...151,015,727 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta involved_in IDA
IBA
IGI		 (PMID:28017329)
(PMID:19279012)		 UniProt
GO_Central
ParkinsonsUK-UCL		 PMID:19279012 PMID:28017329 GO_REF:0000033 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAP1LC3B2 microtubule associated protein 1 light chain 3 beta 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:116,559,381...116,576,606
Ensembl chr12:116,548,105...116,576,606 		JBrowse link
G MAP1LC3C microtubule associated protein 1 light chain 3 gamma involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:241,995,490...242,001,393
Ensembl chr 1:241,995,490...241,999,098 		JBrowse link
G NIPSNAP1 nipsnap homolog 1 involved_in IDA
IEA		 (PMID:30982665) UniProt
Ensembl		 PMID:30982665 GO_REF:0000107 GO_REF:0000117 NCBI chr22:29,554,808...29,581,113
Ensembl chr22:29,554,808...29,581,327 		JBrowse link
G NIPSNAP2 nipsnap homolog 2 involved_in IDA
IEA		 (PMID:30982665) UniProt PMID:30982665 GO_REF:0000117 NCBI chr 7:55,964,585...56,000,179
Ensembl chr 7:55,951,793...56,000,181 		JBrowse link
G NIPSNAP3A nipsnap homolog 3A involved_in IEA UniProt GO_REF:0000117 NCBI chr 9:104,747,683...104,760,120
Ensembl chr 9:104,747,683...104,760,120 		JBrowse link
G NIPSNAP3B nipsnap homolog 3B involved_in IEA UniProt GO_REF:0000117 NCBI chr 9:104,764,129...104,790,899
Ensembl chr 9:104,764,129...104,777,764 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA		 (PMID:33406421) ARUK-UCL
Ensembl		 PMID:33406421 GO_REF:0000107 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G PHB2 prohibitin 2 involved_in IEA
IDA		 (PMID:28017329) Ensembl
UniProt		 PMID:28017329 GO_REF:0000107 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IGI
ISO
IDA		 (PMID:33406421)
(PMID:38081847)		 ARUK-UCL
RGD
UniProt		 PMID:25154397 PMID:33406421 PMID:38081847 RGD:12904014 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IEA
IBA
IDA
ISO		 (PMID:23685073), (PMID:28017329)
(PMID:24949970)		 Ensembl
GO_Central
UniProt
MGI		 PMID:23685073 PMID:24949970 PMID:28017329 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G RETREG1 reticulophagy regulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31446166) Ensembl
MGI		 PMID:31446166 GO_REF:0000107 NCBI chr 5:16,473,053...16,616,997
Ensembl chr 5:16,473,038...16,617,101 		JBrowse link
G RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 involved_in IMP
IEA		 (PMID:34432599) UniProt
InterPro		 PMID:34432599 GO_REF:0000002 NCBI chr 5:41,904,344...41,921,636
Ensembl chr 5:41,904,188...41,921,636 		JBrowse link
G SNX30 sorting nexin family member 30 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:112,749,723...112,885,769
Ensembl chr 9:112,750,760...112,881,671 		JBrowse link
G SNX7 sorting nexin 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:98,661,319...98,760,500
Ensembl chr 1:98,661,701...98,760,500 		JBrowse link
G SPATA33 spermatogenesis associated 33 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:89,657,776...89,670,458
Ensembl chr16:89,657,740...89,671,272 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IGI
IBA		 (PMID:20457763) ParkinsonsUK-UCL
GO_Central		 PMID:20457763 GO_REF:0000033 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in ISS
IMP		 (PMID:33096711) UniProt PMID:33096711 GO_REF:0000024 NCBI chr  X:154,411,539...154,421,726
Ensembl chr  X:154,411,524...154,421,726 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
G ULK2 unc-51 like autophagy activating kinase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:19,770,830...19,867,936
Ensembl chr17:19,770,829...19,867,936 		JBrowse link
G ULK3 unc-51 like kinase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:74,836,118...74,843,156
Ensembl chr15:74,836,118...74,843,346 		JBrowse link
mitophagy by internal vacuole formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPATA18 spermatogenesis associated 18 involved_in IMP
IBA		 (PMID:21264228) UniProt
GO_Central		 PMID:21264228 GO_REF:0000033 NCBI chr 4:52,051,304...52,097,299
Ensembl chr 4:52,051,304...52,097,299 		JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr16:10,944,564...11,182,186
Ensembl chr16:10,944,539...11,182,186 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G RNF41 ring finger protein 41 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24949970) Ensembl
MGI		 PMID:24949970 GO_REF:0000107 NCBI chr12:56,202,179...56,221,969
Ensembl chr12:56,202,179...56,221,933 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSC2 TSC complex subunit 2 involved_in NAS (PMID:26735435) ParkinsonsUK-UCL PMID:26735435 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
G USP30 ubiquitin specific peptidase 30 involved_in ISO
IEA		 RGD
Ensembl		 PMID:24896179 GO_REF:0000107 RGD:13208875 NCBI chr12:109,023,089...109,088,023
Ensembl chr12:109,023,089...109,088,023 		JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G VPS13C vacuolar protein sorting 13 homolog C involved_in IMP (PMID:26942284) ParkinsonsUK-UCL PMID:26942284 NCBI chr15:61,852,389...62,060,447
Ensembl chr15:61,852,389...62,060,473 		JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP3 BCL2 interacting protein 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23698117 GO_REF:0000107 RGD:11561968 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 involved_in IC (PMID:26103054) ParkinsonsUK-UCL PMID:26103054 NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308 		JBrowse link
G FBXO7 F-box protein 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in NAS (PMID:24531622) ParkinsonsUK-UCL PMID:24531622 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IDA (PMID:30217973) UniProt PMID:30217973 NCBI chr11:46,396,412...46,594,023
Ensembl chr11:46,396,414...46,594,125 		JBrowse link
G ATG7 autophagy related 7 ISO RGD PMID:37042059 RGD:407532700 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G CERS1 ceramide synthase 1 involved_in IDA (PMID:22922758) UniProt PMID:22922758 NCBI chr19:18,868,545...18,896,982
Ensembl chr19:18,868,545...18,896,727 		JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in IDA (PMID:38340717) UniProt PMID:38340717 NCBI chr 5:141,923,871...141,942,047
Ensembl chr 5:141,923,855...141,942,047 		JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IDA (PMID:38340717) UniProt PMID:38340717 NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175 		JBrowse link
G FBXO7 F-box protein 7 involved_in IEA
IDA		 (PMID:26310625) Ensembl
ParkinsonsUK-UCL		 PMID:26310625 GO_REF:0000107 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HTT huntingtin involved_in IMP (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,363...3,243,957 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:21102437), (PMID:32939830) UniProt PMID:21102437 PMID:32939830 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO
IDA		 (PMID:26310625) RGD
ParkinsonsUK-UCL		 PMID:26310625 PMID:28608965 RGD:13432560 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382 		JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:119,468,444...119,471,396
Ensembl chr  X:119,468,422...119,471,396 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A involved_in IDA (PMID:23685073) UniProt PMID:23685073 NCBI chr  X:119,574,563...119,584,423
Ensembl chr  X:119,474,802...119,591,083 		JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in IMP (PMID:29307555) UniProt PMID:29307555 NCBI chr 1:12,230,030...12,512,047
Ensembl chr 1:12,230,030...12,512,047 		JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IMP (PMID:24005319) ParkinsonsUK-UCL PMID:24005319 NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906 		JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,391,133...10,403,542
Ensembl chr19:10,391,090...10,420,121 		JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23707074) ARUK-UCL
Ensembl		 PMID:23707074 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G HK2 hexokinase 2 involved_in IMP (PMID:23962723) ParkinsonsUK-UCL PMID:23962723 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in IDA (PMID:30217973) CACAO PMID:30217973 NCBI chr  X:53,532,096...53,686,719
Ensembl chr  X:53,532,096...53,686,752 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IDA
IMP		 (PMID:20457763)
(PMID:20871098), (PMID:23212910)		 ParkinsonsUK-UCL PMID:20457763 PMID:20871098 PMID:23212910 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in IMP (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849 		JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in IMP (PMID:32047033) UniProt PMID:32047033 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A2 ATPase cation transporting 13A2 involved_in TAS (PMID:25548531) ParkinsonsUK-UCL PMID:25548531 NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928 		JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in TAS (PMID:24522549) ParkinsonsUK-UCL PMID:24522549 NCBI chr 1:154,272,629...154,275,875
Ensembl chr 1:154,272,355...154,275,875 		JBrowse link
G HDAC6 histone deacetylase 6 involved_in TAS (PMID:25548531) ParkinsonsUK-UCL PMID:25548531 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in TAS (PMID:24522549) ParkinsonsUK-UCL PMID:24522549 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in TAS (PMID:21563316) ParkinsonsUK-UCL PMID:21563316 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in NAS (PMID:20098416) ParkinsonsUK-UCL PMID:20098416 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:31172217 GO_REF:0000107 RGD:329403053 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106 		JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584 		JBrowse link
G DNM1L dynamin 1 like involved_in IGI (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in IDA (PMID:28381481), (PMID:31908024) DisProt PMID:28381481 PMID:31908024 NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 2:207,762,598...207,769,906
Ensembl chr 2:207,762,598...207,769,906 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625 		JBrowse link
G PARL presenilin associated rhomboid like involved_in ISS
IEA		 (PMID:21355049) ParkinsonsUK-UCL
Ensembl		 PMID:21355049 GO_REF:0000107 NCBI chr 3:183,826,489...183,884,880
Ensembl chr 3:183,829,271...183,884,933 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in IMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G USP36 ubiquitin specific peptidase 36 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr17:78,787,381...78,841,439
Ensembl chr17:78,787,381...78,841,441 		JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 involved_in IGI (PMID:20457763) ParkinsonsUK-UCL PMID:20457763 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G MFN2 mitofusin 2 involved_in IEA
ISS		 Ensembl
ParkinsonsUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G OPTN optineurin involved_in IMP (PMID:25294927) ParkinsonsUK-UCL PMID:25294927 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IDA (PMID:19029340) ParkinsonsUK-UCL PMID:19029340 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:22020285) ParkinsonsUK-UCL PMID:22020285 NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108 		JBrowse link
G TIMM23 translocase of inner mitochondrial membrane 23 involved_in IMP (PMID:37160114) UniProt PMID:37160114 NCBI chr10:45,972,489...46,003,742
Ensembl chr10:45,972,489...46,003,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19688
    cellular process 18940
      process utilizing autophagic mechanism 646
        autophagy 646
          autophagy of mitochondrion 119
            micromitophagy 0
            mitophagy + 97
            mitophagy by internal vacuole formation 1
            negative regulation of autophagy of mitochondrion + 10
            positive regulation of autophagy of mitochondrion + 29
            regulation of autophagy of mitochondrion + 53
Path 2
Term Annotations click to browse term
  biological_process 19688
    cellular process 18940
      metabolic process 12898
        catabolic process 3025
          autophagy 646
            autophagy of mitochondrion 119
              micromitophagy 0
              mitophagy + 97
              mitophagy by internal vacuole formation 1
              negative regulation of autophagy of mitochondrion + 10
              positive regulation of autophagy of mitochondrion + 29
              regulation of autophagy of mitochondrion + 53
paths to the root