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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of alternative mRNA splicing, via spliceosome
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Accession:GO:0000381 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
Synonyms:exact_synonym: regulation of alternative nuclear mRNA splicing, via spliceosome
 broad_synonym: splice site selection


show annotations for term's descendants           Sort by:
regulation of alternative mRNA splicing, via spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arb2a ARB2 cotranscriptional regulator A involved_in ISO (PMID:29311329) RGD PMID:29311329 NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162 		JBrowse link
G Arglu1 arginine and glutamate rich 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30698747)		 UniProt
RGD		 PMID:30698747 GO_REF:0000024 NCBI chr16:80,753,300...80,777,350
Ensembl chr16:80,753,315...80,777,349 		JBrowse link
G Celf1 CUGBP, Elav-like family member 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:32109384)		 Ensembl
GO_Central
RGD		 PMID:32109384 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426 		JBrowse link
G Celf2 CUGBP, Elav-like family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333 		JBrowse link
G Celf3 CUGBP, Elav-like family member 3 involved_in ISO
IBA		 (PMID:11158314)
GO_REF:0000033		 RGD
GO_Central		 PMID:11158314 GO_REF:0000033 NCBI chr 2:182,116,034...182,130,163
Ensembl chr 2:182,116,073...182,130,163 		JBrowse link
G Celf4 CUGBP, Elav-like family member 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:11158314)
(PMID:19720736)		 RGD PMID:11158314 PMID:19720736 NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786 		JBrowse link
G Celf5 CUGBP, Elav-like family member 5 involved_in ISO
IBA		 (PMID:11158314)
GO_REF:0000033		 RGD
GO_Central		 PMID:11158314 GO_REF:0000033 NCBI chr 7:8,225,787...8,250,322
Ensembl chr 7:8,225,825...8,250,322 		JBrowse link
G Celf6 CUGBP, Elav-like family member 6 involved_in ISO
IBA		 (PMID:14761971)
GO_REF:0000033		 RGD
GO_Central		 PMID:14761971 GO_REF:0000033 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041 		JBrowse link
G Ddx17 DEAD-box helicase 17 involved_in ISO (PMID:23022728) RGD PMID:23022728 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:21343338), (PMID:23022728)
(PMID:23022728)		 RGD PMID:21343338 PMID:23022728 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in IDA PMID:22767602 UniProt PMID:22767602 RGD:8554210 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G Fblim1 filamin binding LIM protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISO
ISS		 (PMID:18653529)
GO_REF:0000024		 RGD
UniProt		 PMID:18653529 GO_REF:0000024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO
IEA		 (PMID:25689357)
GO_REF:0000107		 RGD
Ensembl		 PMID:25689357 GO_REF:0000107 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L involved_in ISO
ISS
IEA		 (PMID:25623890)
GO_REF:0000024
GO_REF:0000107
(PMID:22523384)		 RGD
UniProt
Ensembl		 PMID:22523384 PMID:25623890 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO		 GO_REF:0000107
(PMID:22325991)		 Ensembl
RGD		 PMID:22325991 GO_REF:0000107 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISS
ISO
IDA
IBA		 GO_REF:0000024
(PMID:24514149)
PMID:15345239
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:24514149 PMID:15345239 GO_REF:0000024 GO_REF:0000033, RGD:1358238 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Khdrbs2 KH RNA binding domain containing, signal transduction associated 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:34,447,023...34,953,684
Ensembl chr 9:34,447,056...34,915,530 		JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 involved_in IDA
IBA		 PMID:15345239
GO_REF:0000033		 GO_Central PMID:15345239 GO_REF:0000033, RGD:1358238 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460 		JBrowse link
G Magoh mago homolog, exon junction complex subunit involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22203037)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22203037 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617 		JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 involved_in IMP PMID:31283468 UniProt PMID:31283468 RGD:243049249 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368 		JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:31283468
(PMID:19720736)		 RGD PMID:19720736 PMID:31283468 RGD:243049249 NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937 		JBrowse link
G Myod1 myogenic differentiation 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 PMID:9525963
(PMID:9525963)		 RGD PMID:9525963 PMID:9525963 RGD:8553451 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Nova1 NOVA alternative splicing regulator 1 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:14615540), (PMID:17065982), (PMID:27223325)		 UniProt
Ensembl
GO_Central
RGD		 PMID:14615540 PMID:17065982 PMID:27223325 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:63,780,105...63,905,567
Ensembl chr 6:63,783,489...63,906,289 		JBrowse link
G Nova2 NOVA alternative splicing regulator 2 involved_in ISO
IBA		 (PMID:32197073)
GO_REF:0000033
(PMID:14615540), (PMID:16041372), (PMID:17065982), (PMID:27223325)		 RGD
GO_Central		 PMID:14615540 PMID:16041372 PMID:17065982 PMID:27223325 PMID:32197073 GO_REF:0000033 NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021 		JBrowse link
G Nsrp1 nuclear speckle splicing regulatory protein 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21296756)
GO_REF:0000002
GO_REF:0000107		 UniProt
RGD
InterPro
Ensembl		 PMID:21296756 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr10:61,880,807...61,914,471
Ensembl chr10:61,880,825...61,914,471 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 involved_in ISO
ISS		 (PMID:16260624), (PMID:21518792)
GO_REF:0000024		 RGD
UniProt		 PMID:16260624 PMID:21518792 GO_REF:0000024 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397 		JBrowse link
G Puf60 poly-U binding splicing factor 60 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:107,782,799...107,793,759
Ensembl chr 7:107,782,770...107,794,531 		JBrowse link
G Rbfox1 RNA binding fox-1 homolog 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:23300487)		 GO_Central
RGD		 PMID:23300487 GO_REF:0000033 NCBI chr10:8,152,198...10,248,120
Ensembl chr10:8,152,198...9,686,659 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 involved_in
acts_upstream_of_or_within		 IEA
IMP
IBA
ISO		 GO_REF:0000002
GO_REF:0000107
Mcl1
Atp2b1, Mef2a
Fxr1, Mef2a, Mtmr3
Cacna1c
PMID:37548402
GO_REF:0000033
MGI:1926224|MGI:4838182 (PMID:22357600)
(PMID:17101796), (PMID:17715393)		 InterPro
Ensembl
GO_Central
RGD		 PMID:17101796 PMID:17715393 PMID:22357600 PMID:35641779 PMID:31778749 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:329845872, RGD:329845873, RGD:329845874, RGD:329848961, RGD:401901235 NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935 		JBrowse link
G Rbm11 RNA binding motif protein 11 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:21984414)
GO_REF:0000033		 RGD
GO_Central		 PMID:21984414 GO_REF:0000033 NCBI chr11:14,234,851...14,244,092
Ensembl chr11:14,234,890...14,244,090 		JBrowse link
G Rbm15 RNA binding motif protein 15 involved_in ISO
IBA		 (PMID:26575292)
GO_REF:0000033
(PMID:25468569)		 RGD
GO_Central		 PMID:25468569 PMID:26575292 GO_REF:0000033 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Rbm15b RNA binding motif protein 15B involved_in ISO
IBA		 (PMID:16129689)
GO_REF:0000033		 RGD
GO_Central		 PMID:16129689 GO_REF:0000033 NCBI chr 8:107,543,613...107,546,678
Ensembl chr 8:107,525,898...107,551,696 		JBrowse link
G Rbm20 RNA binding motif protein 20 involved_in IMP
IDA		 PMID:33805770
PMID:27289039		 UniProt PMID:33805770 PMID:27289039 RGD:152995553, RGD:152995577 NCBI chr 1:252,683,760...252,907,465
Ensembl chr 1:252,683,771...252,886,060 		JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in ISO
IDA
IBA		 (PMID:26844700), (PMID:26990106), (PMID:29104163)
PMID:27289039
GO_REF:0000033
(PMID:25313962)		 RGD
GO_Central		 PMID:25313962 PMID:26844700 PMID:26990106 PMID:29104163 PMID:27289039 GO_REF:0000033, RGD:152995577 NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102 		JBrowse link
G Rbm25 RNA binding motif protein 25 involved_in ISO
IBA		 (PMID:18663000)
GO_REF:0000033		 RGD
GO_Central		 PMID:18663000 GO_REF:0000033 NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854 		JBrowse link
G Rbm25l1 RNA binding motif protein 25-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:10,267,026...10,270,510
Ensembl chr10:10,267,260...10,269,710
Ensembl chr 6:10,267,260...10,269,710 		JBrowse link
G Rbm4 RNA binding motif protein 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:12628928), (PMID:16260624), (PMID:16777844), (PMID:16934801), (PMID:21518792)
MGI:5467987|MGI:5467988 (PMID:23129807)		 RGD PMID:12628928 PMID:16260624 PMID:16777844 PMID:16934801 PMID:21518792 More... NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:31358901) RGD PMID:31358901 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Rbm5 RNA binding motif protein 5 involved_in ISO
ISS
IEA		 (PMID:18840686), (PMID:18951082)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18840686 PMID:18951082 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430 		JBrowse link
G Rbm8a RNA binding motif protein 8A involved_in ISS
ISO		 GO_REF:0000024
(PMID:22203037)		 UniProt
RGD		 PMID:22203037 GO_REF:0000024 NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959 		JBrowse link
G Rbmx RNA binding motif protein, X-linked involved_in ISO
IEA		 (PMID:12165565), (PMID:12761049)
GO_REF:0000107		 RGD
Ensembl		 PMID:12165565 PMID:12761049 GO_REF:0000107 NCBI chr  X:135,305,237...135,314,806
Ensembl chr  X:135,305,325...135,314,743 		JBrowse link
G Rbmxl1 Rbmx like 1 involved_in IDA PMID:19282290 UniProt PMID:19282290 RGD:2316827 NCBI chr19:29,407,902...29,411,519
Ensembl chr19:29,407,912...29,412,859 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor involved_in IMP PMID:37548402 UniProt PMID:37548402 RGD:401901235 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426 		JBrowse link
G Rbpms2 RNA binding protein, mRNA processing factor 2 involved_in IDA PMID:31283468 UniProt PMID:31283468 RGD:243049249 NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
ISO		 GO_REF:0000024
(PMID:21884984)		 UniProt
RGD		 PMID:21884984 GO_REF:0000024 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 involved_in ISO
ISS		 (PMID:22203037)
GO_REF:0000024		 RGD
UniProt		 PMID:22203037 GO_REF:0000024 NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858 		JBrowse link
G Sap18 Sin3A associated protein 18 involved_in ISO (PMID:20966198), (PMID:22203037) RGD PMID:20966198 PMID:22203037 NCBI chr15:31,943,228...31,947,534
Ensembl chr15:31,943,230...31,950,038
Ensembl chr10:31,943,230...31,950,038 		JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:55,856,691...55,875,262
Ensembl chr 5:55,856,246...55,875,300 		JBrowse link
G Srrm4 serine/arginine repetitive matrix 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:29961578)
MGI:1856676 (PMID:23055939)
(PMID:25727884)		 RGD PMID:23055939 PMID:25727884 PMID:29961578 NCBI chr12:39,998,975...40,158,897
Ensembl chr12:39,999,488...40,155,725 		JBrowse link
G Srsf12 serine and arginine rich splicing factor 12 involved_in ISO (PMID:11684676) RGD PMID:11684676 NCBI chr 5:47,606,526...47,631,509
Ensembl chr 5:47,606,285...47,629,778 		JBrowse link
G Srsf19 serine and arginine rich splicing factor 19 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:45,695,314...45,741,153
Ensembl chr  X:45,695,313...45,741,134 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:21470964)
GO_REF:0000033		 RGD
GO_Central		 PMID:21470964 GO_REF:0000033 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:24440982)
(PMID:23132731)		 UniProt
RGD		 PMID:23132731 PMID:24440982 GO_REF:0000024 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860 		JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 involved_in ISO
ISS		 (PMID:20932480)
GO_REF:0000024		 RGD
UniProt		 PMID:20932480 GO_REF:0000024 NCBI chr 5:138,445,284...138,487,544
Ensembl chr 5:138,445,295...138,487,477 		JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein involved_in ISO (PMID:14966131), (PMID:17580305)
(PMID:10938105), (PMID:11514562)		 RGD PMID:10938105 PMID:11514562 PMID:14966131 PMID:17580305 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586 		JBrowse link
G Tra2b transformer 2 beta involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12165565), (PMID:12761049), (PMID:25689357)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12165565 PMID:12761049 PMID:25689357 GO_REF:0000024 GO_REF:0000107 NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249 		JBrowse link
G Wtap WT1 associated protein involved_in ISO
IBA		 (PMID:24407421)
GO_REF:0000033		 RGD
GO_Central		 PMID:24407421 GO_REF:0000033 NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065 		JBrowse link
G Ythdc1 YTH N6-methyladenosine RNA binding protein C1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:29799838)		 Ensembl
GO_Central
RGD		 PMID:29799838 GO_REF:0000033 GO_REF:0000107 NCBI chr14:21,185,438...21,215,934
Ensembl chr14:21,185,440...21,216,028 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISO
IEA
ISS		 (PMID:24514149)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24514149 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        regulation of metabolic process 6747
          regulation of primary metabolic process 5650
            regulation of RNA splicing 173
              regulation of mRNA splicing, via spliceosome 114
                regulation of alternative mRNA splicing, via spliceosome 62
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        primary metabolic process 10582
          nucleobase-containing compound metabolic process 5795
            nucleic acid metabolic process 5186
              RNA metabolic process 4611
                RNA biosynthetic process 4331
                  RNA processing 969
                    RNA splicing 440
                      RNA splicing, via transesterification reactions 320
                        RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 320
                          mRNA splicing, via spliceosome 320
                            alternative mRNA splicing, via spliceosome 80
                              regulation of alternative mRNA splicing, via spliceosome 62
paths to the root