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ONTOLOGY REPORT - ANNOTATIONS


Term:response to oxygen radical
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Accession:GO:0000305 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.


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cellular response to superoxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADPRS ADP-ribosylserine hydrolase IEA Ensembl GO_REF:0000107 NCBI chr 6:92,238,467...92,244,515
Ensembl chr 6:92,237,354...92,244,518
JBrowse link
G GLRX2 glutaredoxin 2 ISO RGD PMID:25126518 RGD:9686060 NCBI chr10:679,305...689,890 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO (MGI:MGI:5523722|PMID:24191052) MGI PMID:24191052 MGI:MGI:5523722 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,159...14,241,197
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule IEA Ensembl GO_REF:0000107 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G DHFR dihydrofolate reductase IEA Ensembl GO_REF:0000107 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G FBLN5 fibulin 5 IEA Ensembl GO_REF:0000107 NCBI chr 7:113,423,629...113,526,412
Ensembl chr 7:113,423,629...113,522,069
JBrowse link
G GCH1 GTP cyclohydrolase 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:184,201,232...184,264,060
Ensembl chr 1:184,202,007...184,257,315
JBrowse link
G LOC100511343 platelet glycoprotein 4-like IEA Ensembl GO_REF:0000107 NCBI chr 9:99,601,863...99,670,275
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 IEA Ensembl GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:3616392|PMID:16371425) MGI PMID:16371425 MGI:MGI:3616392 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,874...62,110,058
JBrowse link
G CCS copper chaperone for superoxide dismutase IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr 2:5,819,471...5,833,263
Ensembl chr 2:5,819,471...5,836,064
JBrowse link
G FANCC FA complementation group C ISO (MGI:MGI:2149223|PMID:11493445) MGI PMID:11493445 MGI:MGI:2149223 NCBI chr10:26,796,546...27,055,271 JBrowse link
G MPO myeloperoxidase IEA Ensembl GO_REF:0000107 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904
JBrowse link
G MT3 metallothionein 3 ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,721...18,789,137
JBrowse link
G NOS3 nitric oxide synthase 3 IEA Ensembl GO_REF:0000107 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G PRDX1 peroxiredoxin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,520...165,861,442
JBrowse link
G PRDX2 peroxiredoxin 2 IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,796...66,213,567
JBrowse link
G SOD1 superoxide dismutase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G SOD2 superoxide dismutase 2 IEA GOC GO_REF:0000108 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,651,280...7,691,723
JBrowse link
G SOD3 superoxide dismutase 3 IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr 8:18,796,633...18,802,156
Ensembl chr 8:18,796,636...18,802,154
JBrowse link
response to superoxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC6 ERCC excision repair 6, chromatin remodeling factor IEA Ensembl GO_REF:0000107 NCBI chr14:89,998,125...90,075,911
Ensembl chr14:90,002,024...90,075,898
JBrowse link
G SOD1 superoxide dismutase 1 ISO (PMID:16790527)
(MGI:MGI:1201750|PMID:9516486), (MGI:MGI:1314762|PMID:9788901)
(MGI:MGI:3611643|PMID:16357131)
UniProtKB
MGI
PMID:9516486, PMID:9788901, PMID:16357131, PMID:16790527 MGI:MGI:1201750, MGI:MGI:1314762, MGI:MGI:3611643 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G SOD2 superoxide dismutase 2 ISO (PMID:16179351)
(MGI:MGI:1930860|PMID:11156968)
(MGI:MGI:3691744|PMID:15642323)
BHF-UCL
MGI
PMID:11156968, PMID:15642323, PMID:16179351 MGI:MGI:1930860, MGI:MGI:3691744 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,651,280...7,691,723
JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:12372827 RGD:727448 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,333,153...8,365,558
JBrowse link
G UCP3 uncoupling protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:8,378,023...8,389,452
Ensembl chr 9:8,378,019...8,386,211
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    response to stimulus 8984
      response to chemical 5484
        response to inorganic substance 789
          response to oxygen radical 24
            cellular response to oxygen radical + 21
            response to superoxide + 24
Path 2
Term Annotations click to browse term
  biological_process 16545
    response to stimulus 8984
      response to stress 3633
        response to oxidative stress 525
          response to reactive oxygen species 292
            response to oxygen radical 24
              cellular response to oxygen radical + 21
              response to superoxide + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.