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ONTOLOGY REPORT - ANNOTATIONS


Term:response to oxygen radical
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Accession:GO:0000305 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.


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response to oxygen radical term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TXNRD2 thioredoxin reductase 2 TAS (PMID:10455115) UniProtKB PMID:10455115 NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820
JBrowse link
cellular response to superoxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADPRS ADP-ribosylserine hydrolase IMP (PMID:30401461) UniProt PMID:30401461 NCBI chr 1:36,088,885...36,093,932
Ensembl chr 1:36,088,892...36,093,932
JBrowse link
G GLRX2 glutaredoxin 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO (MGI:MGI:5523722|PMID:24191052) MGI PMID:24191052 MGI:MGI:5523722 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP7 bone morphogenetic protein 7 ISS BHF-UCL GO_REF:0000024 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G CD36 CD36 molecule IEA Ensembl GO_REF:0000107 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G DHFR dihydrofolate reductase ISS BHF-UCL GO_REF:0000024 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DHFRP1 dihydrofolate reductase pseudogene 1 ISS BHF-UCL GO_REF:0000024 NCBI chr18:26,167,862...26,171,357
Ensembl chr18:26,170,726...26,171,284
JBrowse link
G FBLN5 fibulin 5 ISS BHF-UCL GO_REF:0000024 NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,412...91,947,987
JBrowse link
G GCH1 GTP cyclohydrolase 1 IMP (PMID:19666465) BHF-UCL PMID:19666465 NCBI chr14:54,842,016...54,902,826
Ensembl chr14:54,842,008...54,902,826
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 IDA (PMID:16945374) HGNC PMID:16945374 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G ATP7A ATPase copper transporting alpha ISS UniProtKB GO_REF:0000024 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G CCS copper chaperone for superoxide dismutase IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr11:66,593,162...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G FANCC FA complementation group C IEA Ensembl GO_REF:0000107 NCBI chr 9:95,099,054...95,317,730
Ensembl chr 9:95,099,054...95,426,796
JBrowse link
G MPO myeloperoxidase IEA Ensembl GO_REF:0000107 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MT3 metallothionein 3 IDA (PMID:12383939) UniProtKB PMID:12383939 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G NOS3 nitric oxide synthase 3 IDA (PMID:19666465) BHF-UCL PMID:19666465 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 IEA GOC GO_REF:0000108 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PRDX1 peroxiredoxin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,511,036...45,523,047
JBrowse link
G PRDX2 peroxiredoxin 2 IDA
IBA
(PMID:20978343)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:20978343, PMID:21873635 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G SOD1 superoxide dismutase 1 IC
IBA
ISS
IEA
(PMID:24567322)
(PMID:21873635)
ParkinsonsUK-UCL
GO_Central
UniProtKB
GOC
PMID:21873635, PMID:24567322 GO_REF:0000024, GO_REF:0000108 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 IMP
IEA
(PMID:16179351) BHF-UCL
GOC
PMID:16179351 GO_REF:0000108 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:24,795,478...24,800,845
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
response to superoxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC6 ERCC excision repair 6, chromatin remodeling factor IEA Ensembl GO_REF:0000107 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,470...49,539,538
JBrowse link
G SOD1 superoxide dismutase 1 IDA (PMID:16790527) UniProtKB PMID:16790527 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 IMP (PMID:16179351) BHF-UCL PMID:16179351 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G UCP2 uncoupling protein 2 IEA Ensembl GO_REF:0000107 NCBI chr11:73,974,671...73,983,202
Ensembl chr11:73,974,672...73,983,246
JBrowse link
G UCP3 uncoupling protein 3 IEA Ensembl GO_REF:0000107 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    response to stimulus 10152
      response to chemical 5626
        response to inorganic substance 840
          response to oxygen radical 27
            cellular response to oxygen radical + 23
            response to superoxide + 26
Path 2
Term Annotations click to browse term
  biological_process 18670
    response to stimulus 10152
      response to stress 4579
        response to oxidative stress 566
          response to reactive oxygen species 309
            response to oxygen radical 27
              cellular response to oxygen radical + 23
              response to superoxide + 26
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.