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ONTOLOGY REPORT - ANNOTATIONS


Term:response to oxygen radical
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Accession:GO:0000305 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.


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cellular response to superoxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADPRS ADP-ribosylserine hydrolase IEA Ensembl GO_REF:0000107 NCBI chr15:6,116,516...6,122,330
Ensembl chr15:6,116,500...6,123,798
JBrowse link
G GLRX2 glutaredoxin 2 ISO RGD PMID:25126518 RGD:9686060 NCBI chr38:5,963,800...5,971,673
Ensembl chr38:5,964,039...5,971,676
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO (MGI:MGI:5523722|PMID:24191052) MGI PMID:24191052 MGI:MGI:5523722 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639
JBrowse link
G FBLN5 fibulin 5 IEA Ensembl GO_REF:0000107 NCBI chr 8:1,162,203...1,231,809
Ensembl chr 8:1,162,923...1,231,719
JBrowse link
G GCH1 GTP cyclohydrolase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 IEA Ensembl GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837
JBrowse link
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:3616392|PMID:16371425) MGI PMID:16371425 MGI:MGI:3616392 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G CCS copper chaperone for superoxide dismutase IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr18:50,748,039...50,759,270
Ensembl chr18:50,748,041...50,759,191
JBrowse link
G FANCC FA complementation group C IEA Ensembl GO_REF:0000107 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506
JBrowse link
G LOC475156 peroxiredoxin 1 pseudogene IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:50,791,386...50,792,228 JBrowse link
G MPO myeloperoxidase IEA Ensembl GO_REF:0000107 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820
JBrowse link
G MT3 metallothionein 3 IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
G NOS3 nitric oxide synthase 3 IEA Ensembl GO_REF:0000107 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G PRDX1 peroxiredoxin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:14,834,009...14,855,665
Ensembl chr15:14,838,652...14,862,971
JBrowse link
G PRDX2 peroxiredoxin 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682
JBrowse link
G SOD1 superoxide dismutase 1 ISS
IBA
IEA
(PMID:21873635) UniProtKB
GO_Central
GOC
PMID:21873635 GO_REF:0000024, GO_REF:0000108 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 IEA GOC GO_REF:0000108 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G SOD3 superoxide dismutase 3 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr 3:85,382,698...85,387,144
Ensembl chr 3:85,382,484...85,387,455
JBrowse link
response to superoxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC6 ERCC excision repair 6, chromatin remodeling factor IEA Ensembl GO_REF:0000107 NCBI chr28:1,358,383...1,432,276
Ensembl chr28:1,361,107...1,427,162
JBrowse link
G SOD1 superoxide dismutase 1 ISO (PMID:16790527)
(MGI:MGI:1201750|PMID:9516486), (MGI:MGI:1314762|PMID:9788901)
(MGI:MGI:3611643|PMID:16357131)
UniProtKB
MGI
PMID:9516486, PMID:9788901, PMID:16357131, PMID:16790527 MGI:MGI:1201750, MGI:MGI:1314762, MGI:MGI:3611643 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 ISO (PMID:16179351)
(MGI:MGI:3691744|PMID:15642323)
(MGI:MGI:1930860|PMID:11156968)
BHF-UCL
MGI
PMID:11156968, PMID:15642323, PMID:16179351 MGI:MGI:1930860, MGI:MGI:3691744 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:12372827 RGD:727448 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128
JBrowse link
G UCP3 uncoupling protein 3 IEA Ensembl GO_REF:0000107 NCBI chr21:24,272,522...24,290,304
Ensembl chr21:24,277,896...24,288,639
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    response to stimulus 8559
      response to chemical 5064
        response to inorganic substance 794
          response to oxygen radical 23
            cellular response to oxygen radical + 20
            response to superoxide + 23
Path 2
Term Annotations click to browse term
  biological_process 16187
    response to stimulus 8559
      response to stress 3627
        response to oxidative stress 525
          response to reactive oxygen species 292
            response to oxygen radical 23
              cellular response to oxygen radical + 20
              response to superoxide + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.