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ONTOLOGY REPORT - ANNOTATIONS


Term:deadenylation-dependent decapping of nuclear-transcribed mRNA
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Accession:GO:0000290 term browser browse the term
Definition:Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
Synonyms:exact_synonym: deadenylation-dependent decapping of nuclear mRNA;   deadenylylation-dependent decapping


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deadenylation-dependent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07066144.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 9:3,921,406...3,965,939 JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 ISO MGI:109382 (MGI:3807625|PMID:18625844) RGD PMID:18625844 MGI:3807625 NCBI chr16:54,899,452...54,918,616
Ensembl chr16:54,899,452...54,918,613
JBrowse link
G Dcp1a decapping mRNA 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:6,542,415...6,583,856
Ensembl chr16:6,542,216...6,587,619
JBrowse link
G Dcp1b decapping mRNA 1B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:151,249,654...151,287,018
Ensembl chr 4:151,250,041...151,285,702
JBrowse link
G Dcp2 decapping mRNA 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:35,489,274...35,671,676
Ensembl chr18:35,489,274...35,672,291
JBrowse link
G Dcps decapping enzyme, scavenger IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 8:36,321,992...36,374,665
Ensembl chr 8:36,321,993...36,374,673
JBrowse link
G LOC100909830 mRNA-decapping enzyme 2-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:78,577,303...78,610,463
Ensembl chr18:78,584,312...78,607,983
JBrowse link
G LOC100912393 mRNA-decapping enzyme 2-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:3,940,948...3,965,964
Ensembl chr18:35,489,274...35,672,291
JBrowse link
G LOC103690064 m7GpppN-mRNA hydrolase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:35,849,655...35,883,568
Ensembl chr18:35,850,132...35,876,585
JBrowse link
G Lsm1 LSM1 homolog, mRNA degradation associated IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:71,046,475...71,057,883
Ensembl chr16:71,046,475...71,057,883
JBrowse link
G Noct nocturnin ISO MGI:1298230 (MGI:3807625|PMID:18625844) RGD PMID:18625844 MGI:3807625 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Pan3 poly(A) specific ribonuclease subunit PAN3 IBA
ISO
PMID:21873635
(MGI:3807625|PMID:18625844)
RGD PMID:18625844, PMID:21873635 MGI:3807625, RGD:13792537 NCBI chr12:9,214,116...9,331,901
Ensembl chr12:9,216,536...9,331,195
JBrowse link
G Patl1 PAT1 homolog 1, processing body mRNA decay factor ISS
ISO
IBA
GO_REF:0000024
(PMID:20584987), (PMID:20852261)
PMID:21873635
UniProt
RGD
PMID:20584987, PMID:20852261, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:228,337,756...228,369,719
Ensembl chr 1:228,337,767...228,369,761
JBrowse link
G Patl2 PAT1 homolog 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:114,065,814...114,075,404
Ensembl chr 3:114,066,840...114,074,803
JBrowse link
negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 ISO (PMID:32354837) RGD PMID:32354837 NCBI chr14:83,412,843...83,455,694
Ensembl chr14:83,412,968...83,455,456
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      negative regulation of metabolic process 3311
        negative regulation of macromolecule metabolic process 3047
          negative regulation of gene expression 2169
            mRNA catabolic process 231
              nuclear-transcribed mRNA catabolic process 116
                deadenylation-dependent decapping of nuclear-transcribed mRNA 15
                  negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA 1
                  regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA + 1
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular aromatic compound metabolic process 5700
          nucleobase-containing compound metabolic process 5488
            nucleic acid metabolic process 4984
              RNA metabolic process 4468
                RNA catabolic process 267
                  mRNA catabolic process 231
                    nuclear-transcribed mRNA catabolic process 116
                      nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 55
                        deadenylation-dependent decapping of nuclear-transcribed mRNA 15
                          negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA 1
                          regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.