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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear-transcribed mRNA poly(A) tail shortening
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Accession:GO:0000289 term browser browse the term
Definition:Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
Synonyms:related_synonym: 3' to 5' mRNA deadenylation;   mRNA deadenylation;   nuclear mRNA poly(A) tail shortening


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nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNOT2 CCR4-NOT transcription complex subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:12,057,269...12,174,405
Ensembl chr10:12,009,762...12,172,427 		JBrowse link
G CNOT3 CCR4-NOT transcription complex subunit 3 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chr 1:103,057,392...103,070,612
Ensembl chr 1:103,057,542...103,066,887 		JBrowse link
G CNOT6 CCR4-NOT transcription complex subunit 6 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:1,209,732...1,277,435
Ensembl chr11:1,212,546...1,270,997 		JBrowse link
G CNOT6L CCR4-NOT transcription complex subunit 6 like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr32:2,192,800...2,305,526
Ensembl chr32:2,145,813...2,306,229 		JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18625844) Ensembl
MGI		 PMID:18625844 GO_REF:0000107 NCBI chr16:40,554,214...40,571,841
Ensembl chr16:40,555,565...40,571,720 		JBrowse link
G MLH1 mutL homolog 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11337385) Ensembl
MGI		 PMID:11337385 GO_REF:0000107 NCBI chr23:6,889,108...6,938,117
Ensembl chr23:6,889,135...6,938,116 		JBrowse link
G PAN2 poly(A) specific ribonuclease subunit PAN2 involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr10:621,286...636,899
Ensembl chr10:621,281...634,495 		JBrowse link
G PAN3 poly(A) specific ribonuclease subunit PAN3 involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr25:11,416,321...11,550,830
Ensembl chr25:11,417,657...11,550,810 		JBrowse link
G PARN poly(A)-specific ribonuclease involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18337750) TreeGrafter
MGI		 PMID:18337750 GO_REF:0000118 NCBI chr 6:28,629,137...28,783,671
Ensembl chr 6:28,629,174...28,783,901 		JBrowse link
G PNLDC1 PARN like ribonuclease domain containing exonuclease 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:49,045,153...49,063,008
Ensembl chr 1:49,044,979...49,062,802 		JBrowse link
G SAMD4A sterile alpha motif domain containing 4A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:30,476,425...30,687,240
Ensembl chr 8:30,476,418...30,687,240 		JBrowse link
G SAMD4B sterile alpha motif domain containing 4B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:113,828,432...113,857,336
Ensembl chr 1:113,828,447...113,857,314 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15814898) Ensembl
MGI		 PMID:15814898 GO_REF:0000107 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065 		JBrowse link
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TENT4A terminal nucleotidyltransferase 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:7,021,743...7,063,049
Ensembl chr34:7,020,187...7,063,129 		JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chr 2:65,068,088...65,147,853
Ensembl chr 2:65,071,111...65,147,896 		JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
Ensembl chr 9:26,736,675...26,740,177 		JBrowse link
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,169,243...35,230,252
Ensembl chr13:35,180,912...35,268,577 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 acts_upstream_of_or_within ISO (PMID:18337750) MGI PMID:18337750 NCBI chr38:70,921...75,149
Ensembl chr38:70,452...72,976 		JBrowse link
G CNOT1 CCR4-NOT transcription complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:58,038,456...58,138,364
Ensembl chr 2:58,038,483...58,137,622 		JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:40,554,214...40,571,841
Ensembl chr16:40,555,565...40,571,720 		JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:6,523,894...6,724,010
Ensembl chr28:6,529,212...6,723,454 		JBrowse link
G EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:24,355,326...24,403,306
Ensembl chr26:24,355,826...24,402,827 		JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chr13:2,563,698...2,580,610
Ensembl chr13:2,564,065...2,580,368 		JBrowse link
G POLR2G RNA polymerase II subunit G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:53,916,431...53,919,724
Ensembl chr18:53,916,435...53,919,549 		JBrowse link
G TNRC6A trinucleotide repeat containing adaptor 6A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:21,247,492...21,454,424
Ensembl chr 6:21,248,948...21,420,719 		JBrowse link
G TNRC6B trinucleotide repeat containing adaptor 6B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:24,852,168...25,094,400
Ensembl chr10:24,813,854...25,094,393 		JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:3,018,599...3,122,664
Ensembl chr 9:3,020,533...3,171,471 		JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
Ensembl chr 9:26,736,675...26,740,177 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    biological regulation 12365
      regulation of biological quality 3298
        regulation of RNA stability 276
          regulation of mRNA stability 257
            mRNA destabilization 182
              nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 56
                nuclear-transcribed mRNA poly(A) tail shortening 26
                  negative regulation of nuclear-transcribed mRNA poly(A) tail shortening 3
                  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 13
                  regulation of nuclear-transcribed mRNA poly(A) tail shortening + 15
Path 2
Term Annotations click to browse term
  biological_process 17878
    biological regulation 12365
      regulation of biological process 12008
        regulation of metabolic process 6335
          regulation of biosynthetic process 5176
            regulation of cellular biosynthetic process 5129
              regulation of macromolecule biosynthetic process 4994
                regulation of gene expression 4876
                  negative regulation of gene expression 1406
                    mRNA catabolic process 338
                      regulation of mRNA catabolic process 274
                        regulation of mRNA stability 257
                          mRNA destabilization 182
                            nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 56
                              nuclear-transcribed mRNA poly(A) tail shortening 26
                                negative regulation of nuclear-transcribed mRNA poly(A) tail shortening 3
                                positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 13
                                regulation of nuclear-transcribed mRNA poly(A) tail shortening + 15
paths to the root