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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear-transcribed mRNA poly(A) tail shortening
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Accession:GO:0000289 term browser browse the term
Definition:Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
Synonyms:related_synonym: 3' to 5' mRNA deadenylation;   mRNA deadenylation;   nuclear mRNA poly(A) tail shortening

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nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot6 CCR4-NOT transcription complex subunit 6 involved_in ISO (PMID:20595389) UniProt PMID:20595389 NCBI chrNW_004955408:170,399...239,492
Ensembl chrNW_004955408:170,399...218,040 		JBrowse link
G Cnot7 CCR4-NOT transcription complex subunit 7 acts_upstream_of_or_within
involved_in		 ISO (PMID:18625844)
(PMID:21336257)		 MGI
UniProt		 PMID:18625844 PMID:21336257 NCBI chrNW_004955463:285,228...306,077
Ensembl chrNW_004955463:285,228...306,077 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:11337385) MGI PMID:11337385 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Parn poly(A)-specific ribonuclease acts_upstream_of_or_within ISO (PMID:18337750) MGI PMID:18337750 NCBI chrNW_004955442:4,255,726...4,421,083
Ensembl chrNW_004955442:4,258,692...4,422,197 		JBrowse link
G Pnldc1 PARN like ribonuclease domain containing exonuclease 1 involved_in ISO (PMID:27515512)
(MGI:5825409|PMID:27515512)		 UniProt PMID:27515512 MGI:5825409 NCBI chrNW_004955439:21,039,638...21,058,558
Ensembl chrNW_004955439:21,035,825...21,058,549 		JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within		 ISO (PMID:23644599)
(PMID:15814898)		 BHF-UCL
MGI		 PMID:15814898 PMID:23644599 NCBI chrNW_004955468:152,744...155,140
Ensembl chrNW_004955468:152,744...155,140 		JBrowse link
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tent4a terminal nucleotidyltransferase 4A involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chrNW_004955504:4,443,051...4,476,373
Ensembl chrNW_004955504:4,443,051...4,476,520 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chrNW_004955433:8,288,432...8,347,347
Ensembl chrNW_004955433:8,288,432...8,347,347 		JBrowse link
G Tob1 transducer of ERBB2, 1 involved_in ISO (PMID:18377426) UniProt PMID:18377426 NCBI chrNW_004955451:10,950,270...10,963,183 JBrowse link
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chrNW_004955461:14,194,268...14,260,949
Ensembl chrNW_004955461:14,205,748...14,253,861 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 acts_upstream_of_or_within ISO (PMID:18337750) MGI PMID:18337750 NCBI chrNW_004955406:39,303,221...39,307,308
Ensembl chrNW_004955406:39,303,175...39,308,778 		JBrowse link
G Cnot1 CCR4-NOT transcription complex subunit 1 involved_in ISO (PMID:23644599)
(PMID:21278420)		 BHF-UCL
UniProt		 PMID:21278420 PMID:23644599 NCBI chrNW_004955433:15,938,791...16,027,547
Ensembl chrNW_004955433:15,938,791...16,027,545 		JBrowse link
G Cnot7 CCR4-NOT transcription complex subunit 7 involved_in ISO (PMID:21278420)
(MGI:5486537|PMID:19716330)		 UniProt PMID:19716330 PMID:21278420 MGI:5486537 NCBI chrNW_004955463:285,228...306,077
Ensembl chrNW_004955463:285,228...306,077 		JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chrNW_004955425:1,032,446...1,224,300
Ensembl chrNW_004955425:1,057,575...1,224,300 		JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:32354837) UniProt PMID:32354837 NCBI chrNW_004955455:5,612,087...5,660,543
Ensembl chrNW_004955455:5,611,093...5,660,104 		JBrowse link
G Pabpc1 poly(A) binding protein cytoplasmic 1 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chrNW_004955417:15,872,906...15,885,246
Ensembl chrNW_004955417:15,868,934...15,885,247 		JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B involved_in ISO (PMID:19716330) UniProt PMID:19716330 NCBI chrNW_004955413:25,820,428...26,060,681
Ensembl chrNW_004955413:25,886,077...26,048,546 		JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C involved_in ISO (PMID:21984185) UniProt PMID:21984185 NCBI chrNW_004955506:4,440,555...4,579,642
Ensembl chrNW_004955506:4,440,555...4,559,070 		JBrowse link
G Tob1 transducer of ERBB2, 1 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chrNW_004955451:10,950,270...10,963,183 JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in ISO (PMID:10330172)
(MGI:5795819|PMID:20595389)
(MGI:5487524|PMID:21278420)		 UniProt PMID:10330172 PMID:20595389 PMID:21278420 MGI:5487524 MGI:5795819 NCBI chrNW_004955468:152,744...155,140
Ensembl chrNW_004955468:152,744...155,140 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    biological regulation 8880
      regulation of biological quality 2623
        regulation of RNA stability 143
          regulation of mRNA stability 132
            mRNA destabilization 74
              nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 36
                nuclear-transcribed mRNA poly(A) tail shortening 17
                  negative regulation of nuclear-transcribed mRNA poly(A) tail shortening 3
                  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 11
                  regulation of nuclear-transcribed mRNA poly(A) tail shortening + 13
Path 2
Term Annotations click to browse term
  biological_process 12346
    biological regulation 8880
      regulation of biological process 8618
        regulation of metabolic process 4808
          regulation of biosynthetic process 3812
            regulation of cellular biosynthetic process 3728
              regulation of macromolecule biosynthetic process 3635
                regulation of gene expression 3524
                  negative regulation of gene expression 965
                    mRNA catabolic process 192
                      regulation of mRNA catabolic process 148
                        regulation of mRNA stability 132
                          mRNA destabilization 74
                            nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 36
                              nuclear-transcribed mRNA poly(A) tail shortening 17
                                negative regulation of nuclear-transcribed mRNA poly(A) tail shortening 3
                                positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 11
                                regulation of nuclear-transcribed mRNA poly(A) tail shortening + 13
paths to the root