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ONTOLOGY REPORT - ANNOTATIONS


Term:tRNA 2'-phosphotransferase activity
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Accession:GO:0000215 term browser browse the term
Definition:Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.
Synonyms:narrow_synonym: yeast 2'-phosphotransferase activity
 broad_synonym: 2'-phosphotransferase activity
 related_synonym: 2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity;   2'-phospho-tRNA:NAD+ phosphotransferase activity;   Tpt1;   Tpt1p
 alt_id: GO:0008665
 xref: EC:2.7.1.160;   MetaCyc:2.7.1.160-RXN;   RHEA:23324



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tRNA 2'-phosphotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpt1 tRNA phosphotransferase 1 enables IBA
ISO
GO_REF:0000033
(PMID:9826666)
GO_Central
RGD
PMID:9826666 GO_REF:0000033 NCBI chr 1:213,615,503...213,620,502
Ensembl chr 1:204,186,295...204,191,294
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  molecular_function 21090
    catalytic activity 6125
      catalytic activity, acting on a nucleic acid 632
        catalytic activity, acting on RNA 391
          catalytic activity, acting on a tRNA 136
            tRNA 2'-phosphotransferase activity 1
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