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ONTOLOGY REPORT - ANNOTATIONS


Term:tRNA-intron endonuclease activity
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Accession:GO:0000213 term browser browse the term
Definition:Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
Synonyms:exact_synonym: splicing endonuclease activity;   tRNA splicing endonuclease activity;   tRNA-intron endoribonuclease activity;   tRNATRPintron endonuclease activity;   transfer ribonucleate intron endoribonuclease activity;   transfer splicing endonuclease activity
 xref: EC:3.1.27.9;   MetaCyc:3.1.27.9-RXN


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tRNA-intron endonuclease activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tsen2 tRNA splicing endonuclease subunit 2 JBrowse link 4 147,455,506 147,490,869 RGD:13792537
G Tsen34 tRNA splicing endonuclease subunit 34 JBrowse link 1 64,023,924 64,031,756 RGD:13792537
G Tsen34l1 tRNA splicing endonuclease subunit 34-like 1 JBrowse link 1 64,092,224 64,100,061 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      catalytic activity, acting on RNA 357
        ribonuclease activity 121
          tRNA-specific ribonuclease activity 15
            tRNA-intron endonuclease activity 3
Path 2
Term Annotations click to browse term
  molecular_function 19619
    catalytic activity 6006
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 782
          nuclease activity 212
            endonuclease activity 121
              endoribonuclease activity 63
                endoribonuclease activity, producing 3'-phosphomonoesters 11
                  tRNA-intron endonuclease activity 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.