A MAPK cascade containing at least the SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase. It starts with the activation of an upstream MAP4K, and continues with the consecutive activation of a MAP3K and a MAP2K. The upstream MAP4K is activated following the detection of stretching of the plasma membrane or alterations of its connections to the cell wall by membrane sensors.
Synonyms:
exact_synonym:
MAPK cascade involved in cell wall organization or biogenesis; MAPKKK cascade involved in cell wall biogenesis; cell integrity MAPK pathway; cell wall biogenesis, MAPKKK cascade
narrow_synonym:
MAPK cascade involved in cell wall biogenesis; Mpk1 cascade; PMK1-MAPK signal transduction pathway; Pmk1 MAPK cell integrity signaling; Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway; Slt2 cascade
related_synonym:
CWI pathway
only_in_taxon:
NCBITaxon:2 ! Viridiplantae or Bacteria or Euglenozoa; NCBITaxon:33090 ! Viridiplantae or Bacteria or Euglenozoa; NCBITaxon:33682 ! Viridiplantae or Bacteria or Euglenozoa