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ONTOLOGY REPORT - ANNOTATIONS

Term:rDNA heterochromatin formation
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Accession:GO:0000183 term browser browse the term
Definition:The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3.
Synonyms:exact_synonym: chromatin silencing at ribosomal DNA;   heterochromatic silencing at rDNA;   rDNA chromatin silencing;   rDNA heterochromatin assembly
 related_synonym: chromatin silencing at rDNA


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rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAZ2A bromodomain adjacent to zinc finger domain 2A involved_in
acts_upstream_of_or_within		 ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165), (MGI:3852588|PMID:19578370)
(PMID:16678107)
(PMID:20168299)		 UniProt
MGI		 PMID:12198165 PMID:16085498 PMID:16678107 PMID:19578370 PMID:20168299 MGI:3587127 MGI:3852313 MGI:3852588 NCBI chr10:834,018...868,817
Ensembl chr10:836,465...863,874 		JBrowse link
G BEND3 BEN domain containing 3 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr12:64,302,403...64,324,396
Ensembl chr12:64,306,140...64,322,725 		JBrowse link
G RRP8 ribosomal RNA processing 8 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:29,907,555...29,917,142
Ensembl chr21:29,907,361...29,918,408 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:18485871) UniProt PMID:18485871 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165) UniProt PMID:12198165 PMID:16085498 MGI:3587127 MGI:3852313 NCBI chr15:42,731,147...42,771,577
Ensembl chr15:42,731,426...42,770,624 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase involved_in ISO (PMID:18485871) UniProt PMID:18485871 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403 		JBrowse link
negative regulation of rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHF2 PHD finger protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,188,014...98,253,930
Ensembl chr 1:98,188,826...98,254,411 		JBrowse link
G PHF8 PHD finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,635,204...45,741,850
Ensembl chr  X:45,571,840...46,081,994 		JBrowse link
regulation of rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone NOT|involved_in ISO (PMID:24071584) UniProt PMID:24071584 NCBI chr11:23,369,957...23,448,235
Ensembl chr11:23,370,300...23,438,219 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular component organization or biogenesis 6943
        cellular component organization 6705
          nucleolar chromatin organization 10
            rDNA heterochromatin formation 9
              negative regulation of rDNA heterochromatin formation 2
              positive regulation of rDNA heterochromatin formation 0
              regulation of rDNA heterochromatin formation + 3
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        regulation of metabolic process 6412
          regulation of biosynthetic process 5261
            regulation of cellular biosynthetic process 5175
              regulation of macromolecule biosynthetic process 5079
                regulation of gene expression 4962
                  negative regulation of gene expression 1416
                    negative regulation of gene expression, epigenetic 150
                      heterochromatin formation 118
                        facultative heterochromatin formation 48
                          rDNA heterochromatin formation 9
                            negative regulation of rDNA heterochromatin formation 2
                            positive regulation of rDNA heterochromatin formation 0
                            regulation of rDNA heterochromatin formation + 3
paths to the root