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ONTOLOGY REPORT - ANNOTATIONS


Term:rDNA heterochromatin formation
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Accession:GO:0000183 term browser browse the term
Definition:The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3.
Synonyms:exact_synonym: chromatin silencing at ribosomal DNA;   heterochromatic silencing at rDNA;   rDNA chromatin silencing;   rDNA heterochromatin assembly
 related_synonym: chromatin silencing at rDNA



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rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz2a bromodomain adjacent to zinc finger domain, 2A involved_in
acts_upstream_of_or_within
ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165), (MGI:3852588|PMID:19578370)
(PMID:16678107), (PMID:20168299)
RGD PMID:12198165 PMID:16085498 PMID:16678107 PMID:19578370 PMID:20168299 MGI:3587127 MGI:3852313 MGI:3852588 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Bend3 BEN domain containing 3 involved_in ISO
IBA
(PMID:26100909)
GO_REF:0000033
RGD
GO_Central
PMID:26100909 GO_REF:0000033 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671
JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:18485871)
UniProt
GO_Central
TreeGrafter
Ensembl
RGD
PMID:18485871 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165) RGD PMID:12198165 PMID:16085498 MGI:3587127 MGI:3852313 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:141,792,589...141,795,257 JBrowse link
negative regulation of rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phf2 PHD finger protein 2 involved_in ISO (PMID:20129925) RGD PMID:20129925 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208
JBrowse link
G Phf8 PHD finger protein 8 involved_in ISO (PMID:20208542) RGD PMID:20208542 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410
JBrowse link
regulation of rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone NOT|involved_in ISO (PMID:24071584) RGD PMID:24071584 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular component organization or biogenesis 7217
        cellular component organization 6909
          nucleolar chromatin organization 11
            rDNA heterochromatin formation 10
              negative regulation of rDNA heterochromatin formation 2
              positive regulation of rDNA heterochromatin formation 0
              regulation of rDNA heterochromatin formation + 3
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        regulation of metabolic process 6575
          regulation of biosynthetic process 5418
            regulation of cellular biosynthetic process 5368
              regulation of macromolecule biosynthetic process 5225
                regulation of gene expression 5109
                  negative regulation of gene expression 1344
                    negative regulation of gene expression, epigenetic 149
                      heterochromatin formation 119
                        facultative heterochromatin formation 52
                          rDNA heterochromatin formation 10
                            negative regulation of rDNA heterochromatin formation 2
                            positive regulation of rDNA heterochromatin formation 0
                            regulation of rDNA heterochromatin formation + 3
paths to the root