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ONTOLOGY REPORT - ANNOTATIONS


Term:rDNA heterochromatin assembly
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Accession:GO:0000183 term browser browse the term
Definition:The assembly of chromatin characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of rDNA.
Synonyms:exact_synonym: chromatin silencing at ribosomal DNA;   heterochromatic silencing at rDNA;   rDNA chromatin silencing
 related_synonym: chromatin silencing at rDNA



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rDNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz2a bromodomain adjacent to zinc finger domain, 2A involved_in
acts_upstream_of_or_within
ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165), (MGI:3852588|PMID:19578370)
(MGI:3653583|PMID:16678107), (MGI:4462332|PMID:20168299)
RGD PMID:12198165 PMID:16085498 PMID:16678107 PMID:19578370 PMID:20168299 MGI:3587127 MGI:3653583 MGI:3852313 MGI:3852588 MGI:4462332 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Bend3 BEN domain containing 3 involved_in ISO
IBA
(PMID:26100909)
PMID:21873635
RGD PMID:26100909 PMID:21873635 RGD:13792537 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671
JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:18485871)
PMID:21873635
UniProt
RGD
PMID:18485871 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:18485871)
Ensembl
RGD
PMID:18485871 GO_REF:0000107 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3587127|PMID:16085498) RGD PMID:16085498 MGI:3587127 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Suv39h1l1 suppressor of variegation 3-9 homolog 1 (Drosophila)-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:14,421,028...14,434,216
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G Ubtf upstream binding transcription factor acts_upstream_of_or_within ISO (MGI:3836497|PMID:19103806) RGD PMID:19103806 MGI:3836497 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969
JBrowse link
negative regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phf2 PHD finger protein 2 involved_in ISO (PMID:20129925) RGD PMID:20129925 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208
JBrowse link
G Phf8 PHD finger protein 8 involved_in ISO (PMID:20208542) RGD PMID:20208542 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410
JBrowse link
regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone NOT|involved_in ISO (PMID:24071584) RGD PMID:24071584 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          nucleolar chromatin organization 12
            rDNA heterochromatin assembly 11
              negative regulation of ribosomal DNA heterochromatin assembly 2
              positive regulation of rDNA heterochromatin assembly 0
              regulation of ribosomal DNA heterochromatin assembly + 3
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          organelle organization 3788
            chromosome organization 900
              chromatin organization 464
                regulation of gene expression, epigenetic 164
                  negative regulation of gene expression, epigenetic 105
                    heterochromatin assembly 99
                      rDNA heterochromatin assembly 11
                        negative regulation of ribosomal DNA heterochromatin assembly 2
                        positive regulation of rDNA heterochromatin assembly 0
                        regulation of ribosomal DNA heterochromatin assembly + 3
paths to the root