Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cytoplasmic exosome (RNase complex)
go back to main search page
Accession:GO:0000177 term browser browse the term
Definition:A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
Synonyms:exact_synonym: cytoplasmic exosome (ribonuclease complex);   cytoplasmic exosome multienzyme ribonuclease complex;   prokaryotic exosome multienzyme ribonuclease complex

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
cytoplasmic exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carhsp1 calcium regulated heat stable protein 1 part_of ISO (PMID:21078874) UniProt PMID:21078874 NCBI chrNW_004955442:9,382,360...9,388,414
Ensembl chrNW_004955442:9,382,354...9,388,414 		JBrowse link
G Dis3l DIS3 like exosome 3'-5' exoribonuclease part_of ISO (PMID:20531386), (PMID:20531389) UniProt PMID:20531386 PMID:20531389 NCBI chrNW_004955450:9,279,323...9,313,402
Ensembl chrNW_004955450:9,279,323...9,314,507 		JBrowse link
G Exosc3 exosome component 3 part_of ISO (PMID:11110791) UniProt PMID:11110791 NCBI chrNW_004955419:28,683,896...28,692,006
Ensembl chrNW_004955419:28,683,896...28,693,395 		JBrowse link
G Gtpbp1 GTP binding protein 1 part_of ISO PMID:21515746 UniProt PMID:21515746 RGD:8553842 NCBI chrNW_004955413:24,823,113...24,849,522
Ensembl chrNW_004955413:24,823,113...24,852,691 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12839
    cellular anatomical structure 12686
      cytoplasm 8529
        cytoplasmic exosome (RNase complex) 4
          bacterial degradosome 0
Path 2
Term Annotations click to browse term
  cellular_component 12839
    protein-containing complex 4310
      catalytic complex 1377
        exoribonuclease complex 23
          exosome (RNase complex) 19
            cytoplasmic exosome (RNase complex) 4
              bacterial degradosome 0
paths to the root