Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:protein phosphatase type 2A complex
go back to main search page
Accession:GO:0000159 term browser browse the term
Definition:A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
Synonyms:exact_synonym: PP2A complex
 narrow_synonym: PP2A-pi;   PP2a-protector
 related_synonym: protein phosphatase 2 complex


show annotations for term's descendants           Sort by:
protein phosphatase type 2A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000069899 part_of IEA GO_REF:0000002
GO_REF:0000118		 InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr 4:162,233,777...162,234,421 JBrowse link
G Ier5 immediate early response 5 located_in ISO (PMID:25816751), (PMID:26496226) RGD PMID:25816751 PMID:26496226 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 part_of ISO (PMID:15687260) RGD PMID:15687260 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha part_of ISO
IMP		 (PMID:17055435), (PMID:17174897)
PMID:19029245
(PMID:16717086)		 RGD PMID:16717086 PMID:17055435 PMID:17174897 PMID:19029245 RGD:8553977 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta part_of ISO (PMID:16717086) RGD PMID:16717086 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha part_of ISO
IBA		 (PMID:17055435), (PMID:17174897)
GO_REF:0000033
(PMID:16717086)		 RGD
GO_Central		 PMID:16717086 PMID:17055435 PMID:17174897 GO_REF:0000033 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta part_of IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha part_of ISO
IEA
IBA		 (PMID:17245430), (PMID:1849734)
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:1849734 PMID:17245430 GO_REF:0000033 GO_REF:0000104 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta part_of IEA
IDA
IBA		 GO_REF:0000104
PMID:12716901
GO_REF:0000033		 UniProt
GO_Central		 PMID:12716901 GO_REF:0000033 GO_REF:0000104, RGD:2314541 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma part_of IEA
IBA		 GO_REF:0000104
GO_REF:0000002
GO_REF:0000033
GO_REF:0000118		 UniProt
InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr14:73,846,547...73,931,489
Ensembl chr14:73,846,547...73,931,864 		JBrowse link
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta part_of ISS
IEA
IBA		 GO_REF:0000024
GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:193,665,918...193,700,277
Ensembl chr 1:193,665,855...193,700,274 		JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha part_of ISO
IBA		 (PMID:17055435)
(PMID:15687260)
GO_REF:0000033		 RGD
GO_Central		 PMID:15687260 PMID:17055435 GO_REF:0000033 NCBI chr 8:101,703,512...101,841,530
Ensembl chr 8:101,704,778...101,841,502 		JBrowse link
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta part_of IBA
ISO		 GO_REF:0000033
(PMID:27998980)		 GO_Central
RGD		 PMID:27998980 GO_REF:0000033 NCBI chr14:88,507...95,750
Ensembl chr14:89,176...95,750 		JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha part_of ISO
IBA		 (PMID:17245430)
GO_REF:0000033		 RGD
GO_Central		 PMID:17245430 GO_REF:0000033 NCBI chr13:102,931,264...102,975,661
Ensembl chr13:102,931,264...102,975,661 		JBrowse link
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:203,527,268...203,535,442
Ensembl chr 1:203,527,270...203,535,416 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma part_of ISO
IBA		 (PMID:17174897)
(PMID:17245430)
GO_REF:0000033		 RGD
GO_Central		 PMID:17174897 PMID:17245430 GO_REF:0000033 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400 		JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872 		JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator part_of ISO
IBA		 (PMID:10318862)
GO_REF:0000033		 RGD
GO_Central		 PMID:10318862 GO_REF:0000033 NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21254
    protein-containing complex 6911
      catalytic complex 1930
        phosphatase complex 56
          protein serine/threonine phosphatase complex 56
            protein phosphatase type 2A complex 19
paths to the root