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ONTOLOGY REPORT - ANNOTATIONS


Term:protein phosphatase type 2A complex
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Accession:GO:0000159 term browser browse the term
Definition:A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
Synonyms:exact_synonym: PP2A complex
 narrow_synonym: PP2A-pi;   PP2a-protector
 related_synonym: protein phosphatase 2 complex



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protein phosphatase type 2A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ier5 immediate early response 5 colocalizes_with
part_of
ISO
IEA
(PMID:25816751), (PMID:26496226)
GO_REF:0000107
RGD
Ensembl
PMID:25816751 PMID:26496226 GO_REF:0000107 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 part_of ISO (PMID:15687260) RGD PMID:15687260 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha part_of ISO
IMP
(PMID:17055435), (PMID:17174897)
PMID:19029245
(MGI:3694309|PMID:16717086)
RGD PMID:16717086 PMID:17055435 PMID:17174897 PMID:19029245 MGI:3694309, RGD:8553977 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta part_of ISO (MGI:3694309|PMID:16717086) RGD PMID:16717086 MGI:3694309 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha part_of ISO
IBA
(PMID:17055435), (PMID:17174897)
PMID:21873635
(MGI:3694309|PMID:16717086)
RGD PMID:16717086 PMID:17055435 PMID:17174897 PMID:21873635 MGI:3694309, RGD:13792537 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha part_of IBA
ISO
PMID:21873635
(PMID:17245430), (PMID:1849734)
RGD PMID:1849734 PMID:17245430 PMID:21873635 RGD:13792537 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta part_of IEA
IBA
IDA
GO_REF:0000104
PMID:21873635
PMID:12716901
UniProt PMID:21873635 PMID:12716901 GO_REF:0000104, RGD:13792537, RGD:2314541 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
JBrowse link
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma part_of IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr14:73,846,547...73,931,178
Ensembl chr14:73,846,547...73,931,864
JBrowse link
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta part_of ISS
IBA
IEA
GO_REF:0000024
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000024 GO_REF:0000104, RGD:13792537 NCBI chr 1:193,665,918...193,700,277
Ensembl chr 1:193,665,855...193,700,274
JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha part_of ISO
IBA
(PMID:17055435)
PMID:21873635
(PMID:15687260)
RGD PMID:15687260 PMID:17055435 PMID:21873635 RGD:13792537 NCBI chr 8:101,703,512...101,841,530
Ensembl chr 8:101,704,778...101,841,502
JBrowse link
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta part_of IBA
ISO
PMID:21873635
(MGI:5828018|PMID:27998980)
RGD PMID:27998980 PMID:21873635 MGI:5828018, RGD:13792537 NCBI chr14:88,507...95,750
Ensembl chr14:89,176...95,750
JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha part_of ISO
IBA
(PMID:17245430)
PMID:21873635
RGD PMID:17245430 PMID:21873635 RGD:13792537 NCBI chr13:102,931,264...102,975,661
Ensembl chr13:102,931,264...102,975,661
JBrowse link
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:203,527,268...203,535,442
Ensembl chr 1:203,527,270...203,535,416
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma part_of IBA
ISO
PMID:21873635
(PMID:17174897)
(PMID:17245430)
RGD PMID:17174897 PMID:17245430 PMID:21873635 RGD:13792537 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
JBrowse link
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400
JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator part_of ISO
IBA
(PMID:10318862)
PMID:21873635
RGD PMID:10318862 PMID:21873635 RGD:13792537 NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19895
    protein-containing complex 5947
      intracellular protein-containing complex 765
        magnesium-dependent protein serine/threonine phosphatase complex 28
          protein phosphatase type 2A complex 18
Path 2
Term Annotations click to browse term
  cellular_component 19895
    protein-containing complex 5947
      catalytic complex 1450
        phosphatase complex 48
          protein serine/threonine phosphatase complex 48
            magnesium-dependent protein serine/threonine phosphatase complex 28
              protein phosphatase type 2A complex 18
paths to the root