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ONTOLOGY REPORT - ANNOTATIONS


Term:SAGA complex
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Accession:GO:0000124 term browser browse the term
Definition:A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
Synonyms:exact_synonym: Spt-Ada-Gcn5-acetyltransferase complex
 narrow_synonym: PCAF complex;   PCAF histone acetylase-associated complex;   SPT3-TAF9-PCAF acetylase complex
 related_synonym: SPT3-TAF9-GCN5 acetylase complex;   STAGA coactivator complex;   STAGA complex
 alt_id: GO:0000125;   GO:0030914



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SAGA complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn7l3 ataxin 7-like 3 part_of ISO
IBA
(PMID:18206972), (PMID:27601583)
PMID:21873635
RGD PMID:18206972 PMID:27601583 PMID:21873635 RGD:13792537 NCBI chr10:87,242,843...87,250,186
Ensembl chr10:87,243,587...87,250,620
JBrowse link
G Eny2 ENY2, transcription and export complex 2 subunit part_of ISO
IBA
(PMID:18206972), (PMID:23591820), (PMID:27601583)
PMID:21873635
RGD PMID:18206972 PMID:23591820 PMID:27601583 PMID:21873635 RGD:13792537 NCBI chr 7:75,581,215...75,605,903
Ensembl chr 7:75,581,240...75,605,897
JBrowse link
G Kat2a lysine acetyltransferase 2A part_of ISO (MGI:3835889|PMID:19103755)
(PMID:11564863)
RGD PMID:11564863 PMID:19103755 MGI:3835889 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166
JBrowse link
G LOC690283 similar to TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:59,890,127...59,892,594
Ensembl chr 1:59,890,278...59,891,258
JBrowse link
G Sgf29 SAGA complex associated factor 29 part_of IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 1:181,238,449...181,271,931
Ensembl chr 1:181,238,468...181,274,781
JBrowse link
G Supt20h SPT20 homolog, SAGA complex component part_of IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 2:138,897,316...138,930,495
Ensembl chr 2:138,897,416...138,930,495
JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component part_of IBA
ISO
PMID:21873635
(PMID:11564863)
RGD PMID:11564863 PMID:21873635 RGD:13792537 NCBI chr 9:15,878,296...16,206,768
Ensembl chr 9:15,868,287...16,206,706
JBrowse link
G Supt7l SPT7 like, STAGA complex subunit gamma part_of IBA
ISO
PMID:21873635
(PMID:11564863)
RGD PMID:11564863 PMID:21873635 RGD:13792537 NCBI chr 6:24,933,941...24,944,656
Ensembl chr 6:24,933,923...24,944,654
JBrowse link
G Tada1 transcriptional adaptor 1 part_of IBA
ISO
IEA
PMID:21873635
(PMID:11564863)
GO_REF:0000107
RGD
Ensembl
PMID:11564863 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504
JBrowse link
G Tada2a transcriptional adaptor 2A part_of ISO (PMID:9674425) RGD PMID:9674425 NCBI chr10:68,966,502...69,014,149
Ensembl chr10:68,966,502...69,014,105
JBrowse link
G Tada2b transcriptional adaptor 2B part_of ISO (MGI:3835889|PMID:19103755) RGD PMID:19103755 MGI:3835889 NCBI chr14:74,279,286...74,290,758
Ensembl chr14:74,279,217...74,290,755
JBrowse link
G Tada3 transcriptional adaptor 3 part_of IBA
ISO
PMID:21873635
(PMID:11564863)
(MGI:3835889|PMID:19103755)
RGD PMID:11564863 PMID:19103755 PMID:21873635 MGI:3835889, RGD:13792537 NCBI chr 4:146,510,213...146,521,975
Ensembl chr 4:146,510,246...146,521,590
JBrowse link
G Taf10 TATA-box binding protein associated factor 10 part_of IBA
ISO
PMID:21873635
(PMID:11564863)
RGD PMID:11564863 PMID:21873635 RGD:13792537 NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376
JBrowse link
G Taf12 TATA-box binding protein associated factor 12 part_of IEA
ISO
GO_REF:0000002
(PMID:11564863)
(PMID:9674425)
(MGI:3835889|PMID:19103755)
InterPro
RGD
PMID:9674425 PMID:11564863 PMID:19103755 GO_REF:0000002 MGI:3835889 NCBI chr 5:144,472,816...144,490,299
Ensembl chr 5:144,472,841...144,488,849
JBrowse link
G Taf5l TATA-box binding protein associated factor 5 like part_of ISO (PMID:11564863) RGD PMID:11564863 NCBI chr19:51,991,704...52,011,001
Ensembl chr19:51,991,708...52,011,295
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247
JBrowse link
G Taf6l TATA-box binding protein associated factor 6 like part_of IEA
ISO
IBA
GO_REF:0000002
(PMID:11564863)
PMID:21873635
InterPro
RGD
PMID:11564863 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 1:205,672,147...205,684,721
Ensembl chr 1:205,672,149...205,684,655
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 part_of IBA
ISO
PMID:21873635
(PMID:11564863)
RGD PMID:11564863 PMID:21873635 RGD:13792537 NCBI chr 2:31,794,316...31,798,324 JBrowse link
G Trrap transformation/transcription domain-associated protein part_of ISO (PMID:11564863) RGD PMID:11564863 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674
JBrowse link
G Usp22 ubiquitin specific peptidase 22 part_of ISO (PMID:18206972), (PMID:18206973), (PMID:27601583) RGD PMID:18206972 PMID:18206973 PMID:27601583 NCBI chr10:45,831,226...45,855,325
Ensembl chr10:45,828,622...45,855,497
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20016
    protein-containing complex 6014
      catalytic complex 1464
        peptidase complex 111
          SAGA complex 20
Path 2
Term Annotations click to browse term
  cellular_component 20016
    cellular anatomical entity 19722
      intracellular anatomical structure 14376
        intracellular organelle 12750
          intracellular membrane-bounded organelle 11196
            nucleus 7033
              nuclear lumen 3932
                nucleoplasm 3468
                  histone acetyltransferase complex 82
                    SAGA-type complex 32
                      SAGA complex 20
paths to the root