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ONTOLOGY REPORT - ANNOTATIONS


Term:nucleotide-excision repair factor 1 complex
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Accession:GO:0000110 term browser browse the term
Definition:One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.
Comment:Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.
Synonyms:exact_synonym: NEF1 complex;   XPA-ERCC1-ERCC4 complex


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nucleotide-excision repair factor 1 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC117889.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:975,697...1,003,352 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO
IBA
(PMID:10413517)
PMID:21873635
RGD PMID:10413517, PMID:21873635 RGD:13792537 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO
IBA
(PMID:10413517)
PMID:21873635
RGD PMID:10413517, PMID:21873635 RGD:13792537 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    protein-containing complex 6104
      DNA repair complex 37
        nucleotide-excision repair complex 14
          nucleotide-excision repair factor 1 complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      organelle 13271
        membrane-bounded organelle 11249
          intracellular membrane-bounded organelle 10505
            nucleus 6974
              nucleotide-excision repair complex 14
                nucleotide-excision repair factor 1 complex 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.