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ONTOLOGY REPORT - ANNOTATIONS


Term:sulfur amino acid metabolic process
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Accession:GO:0000096 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.
Synonyms:exact_synonym: sulfur amino acid metabolism;   sulphur amino acid metabolic process;   sulphur amino acid metabolism



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'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
(PMID:10529246)
GO_REF:0000107
RGD
Ensembl
PMID:10529246 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within
ISO (PMID:24416422)
MGI:1857139 (PMID:15030387)
RGD PMID:15030387 PMID:24416422 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:10212249)
UniProt
RGD
PMID:10212249 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
IEA
(MGI:5294309|PMID:12468440)
GO_REF:0000107
RGD
Ensembl
PMID:12468440 GO_REF:0000107 MGI:5294309 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA
IBA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in ISO
IBA
IEA
(PMID:19428278)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:19428278 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdo1 cysteine dioxygenase type 1 TAS RGD PMID:2334417 RGD:68765 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit involved_in ISS
ISO
GO_REF:0000024
(PMID:2294991)
UniProt
RGD
PMID:2294991 GO_REF:0000024 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:2447852 (PMID:12384496) RGD PMID:12384496 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
homocysteine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blmh bleomycin hydrolase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
JBrowse link
G Cbs cystathionine beta synthase involved_in ISO
ISS
(PMID:18776696), (PMID:24416422)
GO_REF:0000024
RGD
UniProt
PMID:18776696 PMID:24416422 GO_REF:0000024 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:11466310) RGD PMID:11466310 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within
TAS
ISO
(PMID:19010420), (PMID:20031578), (PMID:23981774)
MGI:1857139 (PMID:10953023), (PMID:10993757), (PMID:15131763), (PMID:15555590), (PMID:15622513), (PMID:15916860), (PMID:16226235), (PMID:18541157), (PMID:7878023)
RGD PMID:7878023 PMID:10953023 PMID:10993757 PMID:15131763 PMID:15555590 More... RGD:634704 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 involved_in ISO (PMID:20031578) RGD PMID:20031578 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO
ISS
(PMID:20031578)
GO_REF:0000024
RGD
UniProt
PMID:20031578 GO_REF:0000024 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Mmut methylmalonyl-CoA mutase involved_in ISO (PMID:20031578) RGD PMID:20031578 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEP
ISO
(PMID:20031578) RGD PMID:20031578 PMID:18726220 RGD:2317121 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in IDA
IBA
IMP
GO_REF:0000033 GO_Central
RGD
PMID:11730351 PMID:21121936 GO_REF:0000033, RGD:1601423, RGD:7207080 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
(MGI:3710265|PMID:17369066)
GO_REF:0000033
RGD
GO_Central
PMID:17369066 GO_REF:0000033 MGI:3710265 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (PMID:20031578) RGD PMID:20031578 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
L-cysteine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate aminotransferase involved_in ISO (PMID:18492492) RGD PMID:18492492 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Cbs cystathionine beta synthase involved_in ISO (PMID:15520012) RGD PMID:15520012 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cdo1 cysteine dioxygenase type 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:16611641 GO_REF:0000033, RGD:2301357 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
L-cysteine catabolic process to hypotaurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csad cysteine sulfinic acid decarboxylase involved_in IDA PMID:9635011 UniProt PMID:9635011 RGD:13800536 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
L-cysteine catabolic process to taurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csad cysteine sulfinic acid decarboxylase involved_in IDA PMID:9635011 UniProt PMID:9635011 RGD:13800536 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
L-cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdo1 cysteine dioxygenase type 1 NAS RGD PMID:8973325 RGD:632438 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
IBA
(PMID:18230605)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(PMID:18230605)
Ensembl
GO_Central
RGD
PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:15938715)
UniProt
RGD
PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Apip APAF1 interacting protein involved_in IEA
IBA
ISO
GO_REF:0000041
GO_REF:0000033
(PMID:22837397), (PMID:23285211)
UniProt
GO_Central
RGD
PMID:22837397 PMID:23285211 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA
IBA
ISO
ISS
GO_REF:0000041
GO_REF:0000033
(PMID:15843022)
GO_REF:0000024
UniProt
GO_Central
RGD
PMID:15843022 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO
(PMID:15217352) RGD PMID:15217352 PMID:15845641 RGD:1359026 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA
(PMID:25633902)
GO_REF:0000107
RGD
Ensembl
PMID:25633902 GO_REF:0000107 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2385823 (PMID:15217352)
GO_Central
RGD
PMID:15217352 GO_REF:0000033 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:2180496 (PMID:11158293)
PMID:20424322
GO_REF:0000033
(PMID:23825108)
RGD
GO_Central
PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 GO_REF:0000033, RGD:1359026, RGD:10054082, RGD:1601423 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
IEA
(PMID:11466310)
GO_REF:0000033
GO_REF:0000043
(MGI:3710265|PMID:17369066)
RGD
GO_Central
UniProt
PMID:11466310 PMID:17369066 GO_REF:0000033 GO_REF:0000043 MGI:3710265 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in ISO
ISS
(PMID:10677294)
GO_REF:0000024
RGD
UniProt
PMID:10677294 GO_REF:0000024 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO MGI:3842652 (PMID:17937387) RGD PMID:17937387 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757) RGD PMID:23190757 MGI:5621260 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO UniProtKB:P53128 (PMID:10551815) RGD PMID:10551815 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IMP RGD PMID:21121936 RGD:7207080 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
positive regulation of homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15779086 RGD:2289784 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
regulation of cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (PMID:17200146) RGD PMID:17200146 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
regulation of sulfur amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856211 (PMID:1485534) RGD PMID:1485534 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
transsulfuration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase IDA RGD PMID:16636197 RGD:1600624 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in TAS
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:19428278)
GO_Central
Ensembl
InterPro
RGD
PMID:19428278 PMID:15347670 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1600762 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase IDA RGD PMID:17130129 RGD:9685559 NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA
(MGI:5621260|PMID:23190757)
GO_REF:0000107
RGD
Ensembl
PMID:23190757 GO_REF:0000107 MGI:5621260 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      organonitrogen compound metabolic process 5725
        sulfur amino acid metabolic process 31
          cysteine metabolic process + 11
          ergothioneine metabolic process + 0
          homocysteine metabolic process + 13
          methionine metabolic process + 14
          negative regulation of sulfur amino acid metabolic process + 0
          positive regulation of sulfur amino acid metabolic process + 1
          regulation of sulfur amino acid metabolic process + 3
          sulfur amino acid biosynthetic process + 15
          sulfur amino acid catabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      cellular metabolic process 9669
        organic acid metabolic process 1025
          oxoacid metabolic process 1014
            carboxylic acid metabolic process 999
              sulfur amino acid metabolic process 31
                cysteine metabolic process + 11
                ergothioneine metabolic process + 0
                homocysteine metabolic process + 13
                methionine metabolic process + 14
                negative regulation of sulfur amino acid metabolic process + 0
                positive regulation of sulfur amino acid metabolic process + 1
                regulation of sulfur amino acid metabolic process + 3
                sulfur amino acid biosynthetic process + 15
                sulfur amino acid catabolic process + 7
paths to the root