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ONTOLOGY REPORT - ANNOTATIONS

Term:sulfur amino acid metabolic process
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Accession:GO:0000096 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.
Synonyms:exact_synonym: sulfur amino acid metabolism;   sulphur amino acid metabolic process;   sulphur amino acid metabolism


show annotations for term's descendants           Sort by:
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA		 (PMID:10529246)
GO_REF:0000107		 RGD
Ensembl		 PMID:10529246 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within		 ISO (PMID:24416422)
MGI:1857139 (MGI:3044255|PMID:15030387)		 RGD PMID:15030387 PMID:24416422 MGI:3044255 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cth cystathionine gamma-lyase involved_in IDA
ISS
ISO
IEA		 GO_REF:0000024
(PMID:10212249)
GO_REF:0000041		 UniProt
RGD		 PMID:10212249 PMID:9359866 GO_REF:0000024 GO_REF:0000041, RGD:1359024 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
IEA		 (MGI:5294309|PMID:12468440)
GO_REF:0000107		 RGD
Ensembl		 PMID:12468440 GO_REF:0000107 MGI:5294309 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in TAS
IBA
IEA		 PMID:21873635
GO_REF:0000104		 UniProt
RGD		 PMID:9359866 PMID:21873635 GO_REF:0000104, RGD:1359024, RGD:13792537 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA GO_REF:0000002
GO_REF:0000104		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cth cystathionine gamma-lyase involved_in ISO
IBA
IEA		 (PMID:19428278)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:19428278 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdo1 cysteine dioxygenase type 1 TAS RGD PMID:2334417 RGD:68765 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit involved_in ISS
ISO		 GO_REF:0000024
(PMID:2294991)		 UniProt
RGD		 PMID:2294991 GO_REF:0000024 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:2447852 (MGI:2447526|PMID:12384496) RGD PMID:12384496 MGI:2447526 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
homocysteine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blmh bleomycin hydrolase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212 		JBrowse link
G Cbs cystathionine beta synthase involved_in ISO
ISS		 (PMID:18776696), (PMID:24416422)
GO_REF:0000024		 RGD
UniProt		 PMID:18776696 PMID:24416422 GO_REF:0000024 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:11466310) RGD PMID:11466310 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within		 TAS
IDA
ISO		 (PMID:19010420), (PMID:20031578), (PMID:23981774)
MGI:1857139 (MGI:1888627|PMID:10953023), (MGI:1890086|PMID:10993757), (MGI:3039983|PMID:15131763), (MGI:3510570|PMID:15555590), (MGI:3611588|PMID:15916860), (MGI:3656462|PMID:15622513), (MGI:3663564|PMID:16226235), (MGI:3798351|PMID:18541157), (MGI:71081|PMID:7878023)		 RGD PMID:7878023 PMID:10953023 PMID:10993757 PMID:15131763 PMID:15555590 More... MGI:1888627 MGI:1890086 MGI:3039983 MGI:3510570 MGI:3611588 MGI:3656462 MGI:3663564 MGI:3798351 MGI:71081, RGD:634704, RGD:1359024 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 involved_in ISO (PMID:20031578) RGD PMID:20031578 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Cth cystathionine gamma-lyase IDA RGD PMID:9359866 RGD:1359024 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO
ISS		 (PMID:20031578)
GO_REF:0000024		 RGD
UniProt		 PMID:20031578 GO_REF:0000024 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Mmut methylmalonyl-CoA mutase involved_in ISO (PMID:20031578) RGD PMID:20031578 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEP
ISO		 (PMID:20031578) RGD PMID:20031578 PMID:18726220 RGD:2317121 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in IDA
IBA
IMP		 PMID:21873635 RGD
GO_Central		 PMID:11730351 PMID:21873635 PMID:21121936 RGD:1601423, RGD:13792537, RGD:7207080 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IBA
ISO		 PMID:21873635
(MGI:3710265|PMID:17369066)		 RGD PMID:17369066 PMID:21873635 MGI:3710265, RGD:13792537 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (PMID:20031578) RGD PMID:20031578 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
L-cysteine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate aminotransferase involved_in ISO (PMID:18492492) RGD PMID:18492492 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Cbs cystathionine beta synthase involved_in ISO (PMID:15520012) RGD PMID:15520012 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16611641 PMID:21873635 RGD:2301357, RGD:13792537 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
L-cysteine catabolic process to hypotaurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csad cysteine sulfinic acid decarboxylase involved_in IDA PMID:9635011 UniProt PMID:9635011 RGD:13800536 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615 		JBrowse link
L-cysteine catabolic process to taurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csad cysteine sulfinic acid decarboxylase involved_in IDA PMID:9635011 UniProt PMID:9635011 RGD:13800536 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615 		JBrowse link
L-cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdo1 cysteine dioxygenase type 1 NAS RGD PMID:8973325 RGD:632438 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
IBA		 (PMID:18230605)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:18230605 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:18230605)		 Ensembl
RGD		 PMID:18230605 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA
ISS
ISO		 GO_REF:0000041
GO_REF:0000024
(PMID:15938715)		 UniProt
RGD		 PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA
IBA
ISO		 GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)		 UniProt
RGD		 PMID:22837397 PMID:23285211 PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA
ISO
IBA
ISS		 GO_REF:0000041
(PMID:15843022)
PMID:21873635
GO_REF:0000024		 UniProt
RGD		 PMID:15843022 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:103,873,020...103,939,406
Ensembl chr 5:103,873,020...103,939,406 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO		 (MGI:3510291|PMID:15217352) RGD PMID:15217352 PMID:15845641 MGI:3510291, RGD:1359026 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 (PMID:25633902)
GO_REF:0000107		 RGD
Ensembl		 PMID:25633902 GO_REF:0000107 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2385823 (MGI:3510291|PMID:15217352)
PMID:21873635		 RGD PMID:15217352 PMID:21873635 MGI:3510291, RGD:13792537 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within		 IDA
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000117
MGI:2180496 (MGI:1930456|PMID:11158293)
(PMID:23825108)		 UniProt
RGD		 PMID:11158293 PMID:23825108 PMID:15845641 PMID:21873635 PMID:11730351 GO_REF:0000117 MGI:1930456, RGD:1359026, RGD:13792537, RGD:1601423 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA		 (PMID:11466310)
(MGI:3710265|PMID:17369066)
PMID:21873635		 RGD PMID:11466310 PMID:17369066 PMID:21873635 MGI:3710265, RGD:13792537 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in ISO
ISS		 (PMID:10677294)
GO_REF:0000024		 RGD
UniProt		 PMID:10677294 GO_REF:0000024 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO MGI:3842652 (MGI:3842675|PMID:17937387) RGD PMID:17937387 MGI:3842675 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757) RGD PMID:23190757 MGI:5621260 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO UniProtKB:P53128 (PMID:10551815) RGD PMID:10551815 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IMP RGD PMID:21121936 RGD:7207080 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
positive regulation of homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15779086 RGD:2289784 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
regulation of cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (MGI:3710059|PMID:17200146) RGD PMID:17200146 MGI:3710059 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
regulation of sulfur amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856211 (MGI:60450|PMID:1485534) RGD PMID:1485534 MGI:60450 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
transsulfuration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase IDA RGD PMID:16636197 RGD:1600624 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cth cystathionine gamma-lyase involved_in TAS
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
GO_REF:0000002
(PMID:19428278)		 Ensembl
InterPro
RGD		 PMID:19428278 PMID:15347670 PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:1600762, RGD:13792537 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Mpst mercaptopyruvate sulfurtransferase IDA RGD PMID:17130129 RGD:9685559 NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 (MGI:5621260|PMID:23190757)
GO_REF:0000107		 RGD
Ensembl		 PMID:23190757 GO_REF:0000107 MGI:5621260 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      nitrogen compound metabolic process 8258
        organonitrogen compound metabolic process 6766
          sulfur amino acid metabolic process 31
            cysteine metabolic process + 11
            ergothioneine metabolic process + 0
            homocysteine metabolic process + 13
            methionine metabolic process + 14
            negative regulation of sulfur amino acid metabolic process + 0
            positive regulation of sulfur amino acid metabolic process + 1
            regulation of sulfur amino acid metabolic process + 3
            sulfur amino acid biosynthetic process + 15
            sulfur amino acid catabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 19818
    cellular process 17392
      cellular metabolic process 7496
        organic acid metabolic process 1061
          oxoacid metabolic process 1050
            carboxylic acid metabolic process 1035
              sulfur amino acid metabolic process 31
                cysteine metabolic process + 11
                ergothioneine metabolic process + 0
                homocysteine metabolic process + 13
                methionine metabolic process + 14
                negative regulation of sulfur amino acid metabolic process + 0
                positive regulation of sulfur amino acid metabolic process + 1
                regulation of sulfur amino acid metabolic process + 3
                sulfur amino acid biosynthetic process + 15
                sulfur amino acid catabolic process + 7
paths to the root