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ONTOLOGY REPORT - ANNOTATIONS

Term:G2/M transition of mitotic cell cycle
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Accession:GO:0000086 term browser browse the term
Definition:The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
Synonyms:exact_synonym: mitotic G2/M transition


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G2/M transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G APP amyloid beta precursor protein involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15561424) Ensembl
MGI		 PMID:15561424 GO_REF:0000107 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G ARPP19 cAMP regulated phosphoprotein 19 involved_in ISO (PMID:21164014) UniProt PMID:21164014 NCBI chr15:31,488,156...31,510,404
Ensembl chr15:49,813,447...49,835,051 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 involved_in ISO (PMID:9859993) UniProt PMID:9859993 NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159 		JBrowse link
G BRSK1 BR serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15150265) MGI
Ensembl		 PMID:15150265 GO_REF:0000107 NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659 		JBrowse link
G BRSK2 BR serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,424,873...1,495,630
Ensembl chr11:1,473,129...1,521,339 		JBrowse link
G CALM1 calmodulin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2469574) Ensembl
MGI		 PMID:2469574 GO_REF:0000107 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135 		JBrowse link
G CALM2 calmodulin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2469574) Ensembl
MGI		 PMID:2469574 GO_REF:0000107 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697 		JBrowse link
G CALM3 calmodulin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2469574) Ensembl
MGI		 PMID:2469574 GO_REF:0000107 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135 		JBrowse link
G CCDC57 coiled-coil domain containing 57 involved_in ISO (PMID:32402286) UniProt PMID:32402286 NCBI chr17:76,507,157...76,615,337
Ensembl chr17:82,212,504...82,424,953 		JBrowse link
G CCNA2 cyclin A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:114,016,917...114,024,816
Ensembl chr 4:125,153,810...125,161,302 		JBrowse link
G CCNY cyclin Y involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:35,458,092...35,698,142
Ensembl chr10:36,035,729...36,273,282 		JBrowse link
G CDC25A cell division cycle 25A involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:48,068,601...48,099,806
Ensembl chr 3:49,154,307...49,186,115 		JBrowse link
G CDC25B cell division cycle 25B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:3,877,255...3,883,458
Ensembl chr20:3,626,107...3,645,179 		JBrowse link
G CDC25C cell division cycle 25C involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:133,663,210...133,717,974
Ensembl chr 5:139,795,565...139,842,698 		JBrowse link
G CDK1 cyclin dependent kinase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434 		JBrowse link
G CDK14 cyclin dependent kinase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:82,609,791...83,216,851
Ensembl chr 7:96,211,305...96,731,767 		JBrowse link
G CHEK1 checkpoint kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10859164) Ensembl
MGI		 PMID:10859164 GO_REF:0000107 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981 		JBrowse link
G CHEK2 checkpoint kinase 2 involved_in ISO (PMID:16481012) UniProt PMID:16481012 NCBI chr22:9,757,038...9,811,171 JBrowse link
G CIT citron rho-interacting serine/threonine kinase ISO RGD PMID:12411428 RGD:628497 NCBI chr12:117,264,627...117,456,069
Ensembl chr12:120,641,747...120,832,511 		JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:99,022,732...99,026,623
Ensembl chr10:102,485,732...102,492,301 		JBrowse link
G FBXL7 F-box and leucine rich repeat protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,804,479...16,237,326
Ensembl chr 5:15,643,846...16,075,623 		JBrowse link
G FOXM1 forkhead box M1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISO RGD PMID:11964479 RGD:728684 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188 		JBrowse link
G KAT14 lysine acetyltransferase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19103755) Ensembl
MGI		 PMID:19103755 GO_REF:0000107 NCBI chr20:18,106,400...18,152,231
Ensembl chr20:18,082,402...18,128,470 		JBrowse link
G KDM8 lysine demethylase 8 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:27,577,230...27,595,164 JBrowse link
G LOC100991443 katanin p60 ATPase-containing subunit A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:147,413,892...147,467,587
Ensembl chr 6:152,119,206...152,173,113
Ensembl chr 6:152,119,206...152,173,113 		JBrowse link
G MASTL microtubule associated serine/threonine kinase like involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,264,475...27,296,085
Ensembl chr10:27,626,892...27,658,180 		JBrowse link
G MTA3 metastasis associated 1 family member 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22075476) Ensembl
MGI		 PMID:22075476 GO_REF:0000107 NCBI chr2A:42,593,721...42,847,045
Ensembl chr2A:43,513,514...43,694,314 		JBrowse link
G NES nestin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:132,012,273...132,020,907
Ensembl chr 1:135,835,456...135,844,094 		JBrowse link
G PBX1 PBX homeobox 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22560297) Ensembl
MGI		 PMID:22560297 GO_REF:0000107 NCBI chr 1:139,985,392...140,311,845
Ensembl chr 1:143,778,701...144,104,797 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11809801) Ensembl
MGI		 PMID:11809801 GO_REF:0000107 NCBI chr17:54,698,338...54,761,889
Ensembl chr17:59,824,566...59,887,015 		JBrowse link
G SKP2 S-phase kinase associated protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19056892) Ensembl
MGI
TreeGrafter		 PMID:19056892 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311 		JBrowse link
G TAF2 TATA-box binding protein associated factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:116,421,520...116,523,138
Ensembl chr 8:119,170,327...119,271,405 		JBrowse link
G TPD52L1 TPD52 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:122,943,780...123,053,201
Ensembl chr 6:127,062,573...127,172,174 		JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:108,606,271...108,617,000
Ensembl chr  X:119,034,235...119,049,655 		JBrowse link
G USH1C USH1 protein network component harmonin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,548,501...17,598,923
Ensembl chr11:17,233,854...17,284,256 		JBrowse link
G USP22 ubiquitin specific peptidase 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,606,845...30,650,281
Ensembl chr17:35,468,177...35,511,672 		JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19056892) Ensembl
MGI		 PMID:19056892 GO_REF:0000107 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734 		JBrowse link
mitotic cytokinesis checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP4C charged multivesicular body protein 4C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:78,259,783...78,286,807
Ensembl chr 8:79,879,716...79,906,852 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:49,685,827...49,699,542
Ensembl chr16:69,074,091...69,085,714 		JBrowse link
G ZFYVE19 zinc finger FYVE-type containing 19 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:19,747,606...19,755,185
Ensembl chr15:37,999,283...38,006,744 		JBrowse link
mitotic DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC6 cell division cycle 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:16,987,721...17,002,488
Ensembl chr17:17,211,681...17,225,972 		JBrowse link
G CLSPN claspin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:34,991,082...35,040,515
Ensembl chr 1:36,182,726...36,218,544 		JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:19,944,692...19,956,140
Ensembl chr21:33,317,841...33,328,132 		JBrowse link
G HUS1 HUS1 checkpoint clamp component involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:48,606,848...48,622,194
Ensembl chr 7:48,714,668...48,731,005 		JBrowse link
G HUS1B HUS1 checkpoint clamp component B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:466,508...469,590
Ensembl chr 6:601,288...602,124 		JBrowse link
G NAE1 NEDD8 activating enzyme E1 subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,119,548...47,147,679
Ensembl chr16:66,221,829...66,246,865 		JBrowse link
G ORC1 origin recognition complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:51,630,344...51,666,327
Ensembl chr 1:53,238,377...53,273,653 		JBrowse link
G RAD17 RAD17 checkpoint clamp loader component involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:44,586,083...44,630,719
Ensembl chr 5:46,156,294...46,202,197 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr15:68,270,029...68,322,201
Ensembl chr15:87,476,738...87,528,870 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:130,667,998...130,729,569
Ensembl chr 3:138,143,893...138,203,363 		JBrowse link
G ZNF830 zinc finger protein 830 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:21,823,998...21,825,632
Ensembl chr17:22,116,304...22,117,482 		JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRAXAS1 abraxas 1, BRCA1 A complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:40,711,139...40,736,763
Ensembl chr 4:46,556,892...46,581,573 		JBrowse link
G ATM ATM serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041 		JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:16,755,518...16,767,634
Ensembl chr19:17,729,568...17,742,447 		JBrowse link
G BABAM2 BRISC and BRCA1 A complex member 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr2A:27,884,907...28,338,302
Ensembl chr2A:27,974,917...28,420,519 		JBrowse link
G BLM BLM RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr  X:144,550,320...144,592,795
Ensembl chr  X:154,389,283...154,428,669 		JBrowse link
G BRSK1 BR serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659 		JBrowse link
G C8H10orf90 chromosome 8 C10orf90 homolog involved_in ISO (MGI:4455105|PMID:20154723) UniProt PMID:20154723 MGI:4455105 NCBI chr10:122,987,122...123,243,653
Ensembl chr10:127,259,451...127,357,119 		JBrowse link
G CCNG1 cyclin G1 ISO RGD PMID:9464250 RGD:2316029 NCBI chr 5:158,814,563...158,822,019
Ensembl chr 5:165,592,971...165,598,728 		JBrowse link
G CDC14B cell division cycle 14B involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chr 9:67,596,037...67,715,668 JBrowse link
G CDK1 cyclin dependent kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12937170) Ensembl
MGI
TreeGrafter		 PMID:12937170 GO_REF:0000107 GO_REF:0000118 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CHEK1 checkpoint kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981 		JBrowse link
G CLSPN claspin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:34,991,082...35,040,515
Ensembl chr 1:36,182,726...36,218,544 		JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chr11:46,236,384...46,280,145
Ensembl chr11:46,788,561...46,830,246 		JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:19,944,692...19,956,140
Ensembl chr21:33,317,841...33,328,132 		JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:187,603,600...187,672,006
Ensembl chr 1:192,466,408...192,535,071 		JBrowse link
G FOXN3 forkhead box N3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:69,778,191...70,238,813
Ensembl chr14:89,140,892...89,387,807 		JBrowse link
G FOXO4 forkhead box O4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12048180) Ensembl
MGI		 PMID:12048180 GO_REF:0000107 NCBI chr  X:60,364,466...60,372,147
Ensembl chr  X:70,422,504...70,429,971 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,533,172...2,564,301
Ensembl chr19:3,500,117...3,510,867 		JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:20467439) MGI PMID:20467439 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase acts_upstream_of_or_within ISO (PMID:14614141) MGI PMID:14614141 NCBI chr 3:126,489,125...126,498,034
Ensembl chr 3:133,839,643...133,851,450 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,719,971...64,783,119
Ensembl chr16:84,063,508...84,126,000 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,470,268...14,529,854
Ensembl chr  X:21,825,780...21,883,550 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14690604) TreeGrafter
MGI		 PMID:14690604 GO_REF:0000118 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966 		JBrowse link
G MRNIP MRN complex interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:174,989,967...175,020,550
Ensembl chr 5:182,299,016...182,340,632 		JBrowse link
G NBN nibrin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18614044) Ensembl
MGI
TreeGrafter
InterPro		 PMID:18614044 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) UniProt PMID:21741933 NCBI chr19:44,739,739...44,751,303 JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G RINT1 RAD50 interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:97,522,208...97,567,897
Ensembl chr 7:110,252,776...110,287,702 		JBrowse link
G RPP21 ribonuclease P/MRP subunit p21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,122,996...30,124,784
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G SYF2 SYF2 pre-mRNA splicing factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22448250) Ensembl
MGI		 PMID:22448250 GO_REF:0000107 NCBI chr 1:24,422,931...24,432,870
Ensembl chr 1:25,397,241...25,406,806 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,222,725...27,385,713
Ensembl chr17:27,746,797...27,840,623 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,347,229...30,366,743 JBrowse link
G TAOK3 TAO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:68,270,029...68,322,201
Ensembl chr15:87,476,738...87,528,870 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:130,667,998...130,729,569
Ensembl chr 3:138,143,893...138,203,363 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,205,958...172,321,758
Ensembl chr 5:179,271,577...179,374,229 		JBrowse link
mitotic G2/M transition checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATR ATR serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:139,482,606...139,612,274
Ensembl chr 3:147,075,185...147,196,261 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15254237) Ensembl
MGI		 PMID:15254237 GO_REF:0000107 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G CHEK1 checkpoint kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981 		JBrowse link
G CHFR checkpoint with forkhead and ring finger domains involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:130,318,971...130,366,282
Ensembl chr12:134,923,458...134,968,832
Ensembl chr12:134,923,458...134,968,832 		JBrowse link
G ETAA1 ETAA1 activator of ATR kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:67,455,668...67,470,509
Ensembl chr2A:68,578,554...68,591,534 		JBrowse link
G INIP INTS3 and NABP interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:83,811,378...83,845,638
Ensembl chr 9:111,965,947...111,999,561 		JBrowse link
G INTS3 integrator complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,084,681...129,130,669
Ensembl chr 1:132,714,200...132,759,842 		JBrowse link
G NABP1 nucleic acid binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:78,980,156...78,989,309
Ensembl chr2B:196,895,166...196,903,977 		JBrowse link
G NABP2 nucleic acid binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,685,521...32,693,318
Ensembl chr12:32,937,017...32,944,754 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:56,007,323...56,011,655
Ensembl chr 9:67,544,489...67,545,352 		JBrowse link
negative regulation of G2/M transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 ISO RGD PMID:11278490 RGD:2316109 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981 		JBrowse link
G FHL1 four and a half LIM domains 1 involved_in ISO (PMID:21702045) UniProt PMID:21702045 NCBI chr  X:125,270,340...125,334,961
Ensembl chr  X:135,559,321...135,602,375 		JBrowse link
G GPR132 G protein-coupled receptor 132 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:85,697,589...85,716,764 JBrowse link
G MIIP migration and invasion inhibitory protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:10,770,412...10,783,414
Ensembl chr 1:11,986,808...11,999,330 		JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:8,366,819...8,443,359 JBrowse link
G PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,914,651...1,946,407
Ensembl chr16:3,082,265...3,094,477 		JBrowse link
G RAD21 RAD21 cohesin complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,520,456...113,549,339
Ensembl chr 8:116,063,503...116,092,421 		JBrowse link
G RFPL1 ret finger protein like 1 involved_in ISO (PMID:20725088) UniProt PMID:20725088
G USP47 ubiquitin specific peptidase 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,009,770...12,127,425
Ensembl chr11:11,703,617...11,821,074 		JBrowse link
G WEE1 WEE1 G2 checkpoint kinase involved_in ISO (PMID:7743995), (PMID:8348613), (PMID:8428596) UniProt PMID:7743995 PMID:8348613 PMID:8428596 NCBI chr11:9,706,531...9,722,528 JBrowse link
positive regulation of G2/M transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15561424) Ensembl
MGI		 PMID:15561424 GO_REF:0000107 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G BRD4 bromodomain containing 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10938129) MGI
Ensembl		 PMID:10938129 GO_REF:0000107 NCBI chr19:14,768,239...14,805,770
Ensembl chr19:15,754,930...15,789,600 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387 		JBrowse link
G CCNB1 cyclin B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332 		JBrowse link
G CCND1 cyclin D1 involved_in ISO (PMID:19124461) UniProt PMID:19124461 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CDC25A cell division cycle 25A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:48,068,601...48,099,806
Ensembl chr 3:49,154,307...49,186,115 		JBrowse link
G CDC25B cell division cycle 25B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:3,877,255...3,883,458
Ensembl chr20:3,626,107...3,645,179 		JBrowse link
G CDC25C cell division cycle 25C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:133,663,210...133,717,974
Ensembl chr 5:139,795,565...139,842,698 		JBrowse link
G CDC7 cell division cycle 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:94,158,628...94,183,537
Ensembl chr 1:92,902,631...92,927,203 		JBrowse link
G CDK1 cyclin dependent kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434 		JBrowse link
G CDK4 cyclin dependent kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876 		JBrowse link
G DBF4B DBF4B-CDC7 kinase regulatory subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:12,571,265...12,616,105
Ensembl chr17:12,744,297...12,790,089 		JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:187,603,600...187,672,006
Ensembl chr 1:192,466,408...192,535,071 		JBrowse link
G FBXO5 F-box protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:150,793,020...150,806,008
Ensembl chr 6:155,481,753...155,494,231 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9247342) Ensembl
MGI		 PMID:9247342 GO_REF:0000107 NCBI chr14:45,124,326...45,127,105
Ensembl chr14:63,373,840...63,375,762 		JBrowse link
G MTA3 metastasis associated 1 family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22075476) Ensembl
MGI		 PMID:22075476 GO_REF:0000107 NCBI chr2A:42,593,721...42,847,045
Ensembl chr2A:43,513,514...43,694,314 		JBrowse link
G PBX1 PBX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22560297) Ensembl
MGI		 PMID:22560297 GO_REF:0000107 NCBI chr 1:139,985,392...140,311,845
Ensembl chr 1:143,778,701...144,104,797 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:44,810,880...44,833,438
Ensembl chr15:63,088,084...63,108,077 		JBrowse link
G RAD51B RAD51 paralog B involved_in ISO (PMID:23108668) UniProt PMID:23108668 NCBI chr14:48,399,345...49,314,577
Ensembl chr14:67,281,148...68,110,693 		JBrowse link
G RAD51C RAD51 paralog C involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,769,446...52,808,467
Ensembl chr17:57,621,552...57,660,701 		JBrowse link
G RCC2 regulator of chromosome condensation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:16,353,770...16,386,810
Ensembl chr 1:17,409,432...17,432,031 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:3,956,528...3,999,205
Ensembl chr11:4,068,119...4,110,474 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:98,854,101...98,890,365
Ensembl chr 8:101,019,699...101,052,056 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15998811) Ensembl
MGI		 PMID:15998811 GO_REF:0000107 NCBI chr15:54,285,587...54,371,376
Ensembl chr15:73,881,500...73,966,506 		JBrowse link
G SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 ISO RGD PMID:23110084 RGD:9586362 NCBI chr 7:142,825,864...142,864,159
Ensembl chr 7:154,977,858...155,013,681 		JBrowse link
G STOX1 storkhead box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:65,304,649...65,359,501
Ensembl chr10:67,882,654...67,894,039 		JBrowse link
G VPS4B vacuolar protein sorting 4 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:56,749,439...56,782,660
Ensembl chr18:60,060,285...60,095,109 		JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19056892) Ensembl
MGI		 PMID:19056892 GO_REF:0000107 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734 		JBrowse link
regulation of G2/M transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945 		JBrowse link
G CDK3 cyclin dependent kinase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:69,947,125...69,952,567
Ensembl chr17:75,498,134...75,503,448 		JBrowse link
G CDK4 cyclin dependent kinase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:15582998) BHF-UCL PMID:15582998 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CENPF centromere protein F involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:190,170,414...190,231,478
Ensembl chr 1:195,024,877...195,086,518 		JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22531781) Ensembl
MGI		 PMID:22531781 GO_REF:0000107 NCBI chr17:43,410,385...43,433,784
Ensembl chr17:48,142,864...48,165,537 		JBrowse link
G HACD1 3-hydroxyacyl-CoA dehydratase 1 acts_upstream_of_or_within ISO (PMID:22106411) MGI PMID:22106411 NCBI chr10:17,911,158...17,940,075
Ensembl chr10:18,183,125...18,209,361 		JBrowse link
G KCNH5 potassium voltage-gated channel subfamily H member 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22855790) MGI
Ensembl		 PMID:22855790 GO_REF:0000107 NCBI chr14:43,297,114...43,633,275
Ensembl chr14:61,560,600...61,889,137 		JBrowse link
G KIF14 kinesin family member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,156,870...176,223,093
Ensembl chr 1:180,462,578...180,526,323 		JBrowse link
G PKIA cAMP-dependent protein kinase inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7836431) Ensembl
MGI		 PMID:7836431 GO_REF:0000107 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673 		JBrowse link
G PRKCQ protein kinase C theta ISO RGD PMID:9353339 RGD:1625621 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900 		JBrowse link
G RNASEH2B ribonuclease H2 subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22802351) Ensembl
MGI		 PMID:22802351 GO_REF:0000107 NCBI chr13:32,047,830...32,108,573
Ensembl chr13:50,795,701...50,852,909 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cell cycle process 1277
        cell cycle phase transition 516
          mitotic cell cycle phase transition 413
            G2/M transition of mitotic cell cycle 135
              negative regulation of G2/M transition of mitotic cell cycle + 68
              positive regulation of G2/M transition of mitotic cell cycle + 28
              regulation of G2/M transition of mitotic cell cycle + 105
Path 2
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cell cycle 1587
        cell cycle process 1277
          cell cycle phase transition 516
            mitotic cell cycle phase transition 413
              G2/M transition of mitotic cell cycle 135
                negative regulation of G2/M transition of mitotic cell cycle + 68
                positive regulation of G2/M transition of mitotic cell cycle + 28
                regulation of G2/M transition of mitotic cell cycle + 105
paths to the root