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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA damage checkpoint signaling
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Accession:GO:0000077 term browser browse the term
Definition:A signal transduction process that contributes to a DNA damage checkpoint.
Synonyms:exact_synonym: DNA damage checkpoint;   signal transduction involved in DNA damage checkpoint
 narrow_synonym: DNA damage response, signal transduction resulting in cell cycle arrest
 alt_id: GO:0072422
 xref: Wikipedia:DNA_damage_checkpoint;   Wikipedia:Postreplication_checkpoint


show annotations for term's descendants           Sort by:
DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 (MGI:2679752|PMID:12937170)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:12937170 PMID:21873635 GO_REF:0000096 MGI:2679752 MGI:4834177 MGI:6201960 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atr ataxia telangiectasia and Rad3 related acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 (MGI:2679752|PMID:12937170)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:12937170 PMID:21873635 GO_REF:0000096 MGI:2679752 MGI:4834177 MGI:6201960 NCBI chr 9:95,739,650...95,834,813
Ensembl chr 9:95,739,650...95,833,834 		JBrowse link
G Atrip ATR interacting protein involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 9:108,888,815...108,903,192
Ensembl chr 9:108,887,001...108,903,192 		JBrowse link
G Cdc5l cell division cycle 5-like involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:45,702,809...45,744,633
Ensembl chr17:45,702,810...45,744,663 		JBrowse link
G Cdc5lrt1 cell division cycle 5 like, retrotransposed 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,074,241...118,076,700
Ensembl chr10:118,074,277...118,076,685 		JBrowse link
G Cdc5lrt10 cell division cycle 5 like, retrotransposed 10 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,187,324...118,190,025
Ensembl chr10:118,187,602...118,190,010 		JBrowse link
G Cdc5lrt4 cell division cycle 5 like, retrotransposed 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,094,577...118,097,037
Ensembl chr10:118,094,593...118,097,001 		JBrowse link
G Cdc5lrt5 cell division cycle 5 like, retrotransposed 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,160,141...118,162,889
Ensembl chr10:118,160,466...118,162,874 		JBrowse link
G Cdc5lrt6 cell division cycle 5 like, retrotransposed 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,165,876...118,168,330
Ensembl chr10:118,165,905...118,168,313 		JBrowse link
G Cdc5lrt7 cell division cycle 5 like, retrotransposed 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,171,007...118,173,751
Ensembl chr10:118,171,328...118,173,736 		JBrowse link
G Cdc5lrt8 cell division cycle 5 like, retrotransposed 8 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,176,721...118,179,175
Ensembl chr10:118,176,752...118,179,160 		JBrowse link
G Cdc5lrt9 cell division cycle 5 like, retrotransposed 9 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:118,182,150...118,184,599
Ensembl chr10:118,182,176...118,184,584 		JBrowse link
G Chek1 checkpoint kinase 1 acts_upstream_of_or_within
involved_in		 IMP
IDA
ISO		 (MGI:1860049|PMID:10859164)
(MGI:2449744|PMID:12529385)		 MGI PMID:10859164 PMID:12529385 GO_REF:0000096 MGI:1860049 MGI:2449744 MGI:4834177 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361 		JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO RGD
MGI		 PMID:10435585 GO_REF:0000096 MGI:4417868 RGD:633752 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Clock circadian locomotor output cycles kaput involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639 		JBrowse link
G Clspn claspin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:126,450,738...126,488,326
Ensembl chr 4:126,450,728...126,487,696 		JBrowse link
G Donson downstream neighbor of SON involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:91,463,744...91,485,702
Ensembl chr16:91,473,696...91,485,658 		JBrowse link
G Dot1l DOT1-like, histone H3 methyltransferase (S. cerevisiae) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:80,590,935...80,631,295
Ensembl chr10:80,591,040...80,631,295 		JBrowse link
G Dtx3l deltex 3-like, E3 ubiquitin ligase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:35,746,885...35,759,397
Ensembl chr16:35,746,881...35,759,521 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 2:118,219,065...118,305,715
Ensembl chr 2:118,219,099...118,305,715 		JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947 		JBrowse link
G H2ax H2A.X variant histone involved_in
NOT|acts_upstream_of_or_within		 ISO
IMP		 (PMID:17974976)
(MGI:2179182|PMID:11934988)		 UniProt
MGI		 PMID:11934988 PMID:17974976 MGI:2179182 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Hinfp histone H4 transcription factor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:44,201,509...44,217,003
Ensembl chr 9:44,203,737...44,216,968 		JBrowse link
G Hus1 HUS1 checkpoint clamp component acts_upstream_of_or_within
involved_in		 IMP
ISO		 (MGI:2449744|PMID:12529385) MGI PMID:12529385 GO_REF:0000096 MGI:2449744 MGI:4834177 NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191 		JBrowse link
G Hus1b HUS1 checkpoint clamp component B involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742 		JBrowse link
G Ints7 integrator complex subunit 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:191,307,652...191,355,802
Ensembl chr 1:191,307,748...191,355,800 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:72,115,970...72,272,954
Ensembl chr 2:72,115,981...72,272,954 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 acts_upstream_of_or_within IMP (MGI:2679752|PMID:12937170) MGI PMID:12937170 MGI:2679752 NCBI chr17:28,910,243...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Nbn nibrin acts_upstream_of_or_within ISO (MGI:2449744|PMID:12529385) MGI PMID:12529385 MGI:2449744 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:35,759,360...35,792,975
Ensembl chr16:35,758,840...35,792,975 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:10,872,595...10,886,923
Ensembl chr19:10,872,595...10,886,923 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within IMP (MGI:2679752|PMID:12937170) MGI PMID:12937170 MGI:2679752 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr15:10,486,104...10,499,149
Ensembl chr15:10,486,104...10,499,149 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr13:100,753,672...100,787,569
Ensembl chr13:100,753,672...100,787,559 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in
acts_upstream_of_or_within		 ISO
ISS		 (MGI:1927035|PMID:11058134) MGI PMID:11058134 GO_REF:0000096 MGI:1927035 MGI:4834177 NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296 		JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 6:128,333,962...128,339,876
Ensembl chr 6:128,333,963...128,339,874 		JBrowse link
G Tipin timeless interacting protein acts_upstream_of_or_within IMP (MGI:3706226|PMID:17141802) MGI PMID:17141802 MGI:3706226 NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706 		JBrowse link
G Tiprl TIP41, TOR signalling pathway regulator-like (S. cerevisiae) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:165,039,855...165,110,228
Ensembl chr 1:165,039,855...165,064,565 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within IMP (MGI:3818783|PMID:18045533) MGI PMID:18045533 MGI:3818783 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:25,247,149...25,281,821
Ensembl chr 4:25,248,600...25,281,821 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:48,896,577...48,953,817
Ensembl chr 9:48,896,675...48,953,817 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A (P21) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr10:95,010,601...95,160,000
Ensembl chr10:95,010,608...95,159,995 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Muc1 mucin 1, transmembrane involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chr 9:106,330,181...106,341,211
Ensembl chr 9:106,330,490...106,341,211 		JBrowse link
G Pidd1 p53 induced death domain protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938 		JBrowse link
G Pml promyelocytic leukemia involved_in IMP (MGI:3580934|PMID:15626733) UniProt PMID:15626733 MGI:3580934 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:110,413,532...110,549,509
Ensembl chr12:110,413,554...110,549,496 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113 		JBrowse link
G Ptprv protein tyrosine phosphatase receptor type V acts_upstream_of_or_within IGI (MGI:3589512|PMID:16107883) MGI PMID:16107883 MGI:3589512 NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:172,863,680...172,876,527
Ensembl chr 2:172,862,291...172,876,527 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in IDA
ISO		 (MGI:5882892|PMID:16213212) CAFA
MGI		 PMID:16213212 GO_REF:0000096 MGI:4834177 MGI:5882892 NCBI chr11:68,792,392...68,795,360
Ensembl chr11:68,792,409...68,797,815 		JBrowse link
G Trp53 transformation related protein 53 involved_in
acts_upstream_of_or_within		 ISO
IGI		 (MGI:3589512|PMID:16107883) MGI PMID:16107883 GO_REF:0000096 MGI:3589512 MGI:4834177 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
mitotic DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek2 checkpoint kinase 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Stk33 serine/threonine kinase 33 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:108,878,270...109,038,375
Ensembl chr 7:108,878,430...109,038,288 		JBrowse link
G Zfp830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:5428139|PMID:23213458)		 GO_Central
MGI		 PMID:21873635 PMID:23213458 MGI:5428139 MGI:6201960 NCBI chr11:82,655,171...82,658,448
Ensembl chr11:82,655,171...82,656,761 		JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:91,763,167...91,806,788
Ensembl chr 2:91,763,169...91,806,209 		JBrowse link
G Fbxo31 F-box protein 31 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:122,276,182...122,305,607
Ensembl chr 8:122,276,179...122,305,545 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within IMP (MGI:4366664|PMID:19744960) MGI PMID:19744960 MGI:4366664 NCBI chr 1:87,254,653...87,378,532
Ensembl chr 1:87,254,720...87,378,518 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptprv protein tyrosine phosphatase receptor type V acts_upstream_of_or_within IMP (MGI:3589512|PMID:16107883) MGI PMID:16107883 MGI:3589512 NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:111,997,576...112,026,854
Ensembl chr 8:111,997,576...112,026,854 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:66,851,906...66,856,804
Ensembl chr 9:66,853,368...66,856,798 		JBrowse link
G Sde2 SDE2 telomere maintenance homolog (S. pombe) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:180,678,716...180,695,678
Ensembl chr 1:180,678,692...180,695,678 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within IMP (MGI:3818783|PMID:18045533)
(MGI:5562498|PMID:23993650)		 MGI PMID:18045533 PMID:23993650 MGI:3818783 MGI:5562498 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within
involved_in		 IMP
ISO		 (MGI:3589512|PMID:16107883) MGI PMID:16107883 GO_REF:0000096 MGI:3589512 MGI:4834177 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:7,868,614...7,929,028
Ensembl chr18:7,868,832...7,929,028 		JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 BRCA1 A complex subunit involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:100,952,668...100,993,430
Ensembl chr 5:100,953,058...100,968,831 		JBrowse link
G Atm ataxia telangiectasia mutated involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:71,848,809...71,857,416
Ensembl chr 8:71,849,505...71,857,263 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:31,855,394...32,242,083
Ensembl chr 5:31,855,028...32,242,306 		JBrowse link
G Blm Bloom syndrome, RecQ like helicase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:80,104,741...80,184,896
Ensembl chr 7:80,104,481...80,184,867 		JBrowse link
G Brca1 breast cancer 1, early onset involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:74,460,234...74,499,307
Ensembl chr  X:74,460,234...74,497,607 		JBrowse link
G Brcc3dc BRCA1/BRCA2-containing complex, subunit 3, domain containing involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:108,534,905...108,536,021
Ensembl chr10:108,534,625...108,536,021 		JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:4,693,635...4,718,996
Ensembl chr 7:4,693,603...4,718,996 		JBrowse link
G Ccng1 cyclin G1 involved_in ISO RGD
MGI		 PMID:9464250 GO_REF:0000096 MGI:4417868 RGD:2316029 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138 		JBrowse link
G Cdc14b CDC14 cell division cycle 14B involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chr13:64,337,085...64,423,670
Ensembl chr13:64,337,082...64,423,104 		JBrowse link
G Cdk1 cyclin dependent kinase 1 involved_in
acts_upstream_of_or_within		 IBA
IDA		 (MGI:6201960|PMID:21873635)
(MGI:2679752|PMID:12937170)		 GO_Central
MGI		 PMID:12937170 PMID:21873635 MGI:2679752 MGI:6201960 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:96,798,251...96,807,359
Ensembl chr11:96,798,252...96,807,322 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A (P21) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361 		JBrowse link
G Clspn claspin involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:126,450,738...126,488,326
Ensembl chr 4:126,450,728...126,487,696 		JBrowse link
G D7Ertd443e DNA segment, Chr 7, ERATO Doi 443, expressed involved_in IDA (MGI:4455105|PMID:20154723) UniProt PMID:20154723 MGI:4455105 NCBI chr 7:133,867,509...134,121,888
Ensembl chr 7:133,867,508...134,102,889 		JBrowse link
G Donson downstream neighbor of SON involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:91,463,744...91,485,702
Ensembl chr16:91,473,696...91,485,658 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 1:191,269,468...191,307,656
Ensembl chr 1:191,269,468...191,307,656 		JBrowse link
G Foxn3 forkhead box N3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:99,156,340...99,529,926
Ensembl chr12:99,156,337...99,529,841 		JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within IDA (MGI:2183145|PMID:12048180) MGI PMID:12048180 MGI:2183145 NCBI chr  X:100,297,855...100,304,479
Ensembl chr  X:100,298,134...100,304,479 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:81,202,713...81,214,204
Ensembl chr10:81,202,056...81,214,350 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within IMP (MGI:5432078|PMID:20467439) MGI PMID:20467439 MGI:5432078 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Mbd4 methyl-CpG binding domain protein 4 acts_upstream_of_or_within IMP (MGI:2682526|PMID:14614141) MGI PMID:14614141 MGI:2682526 NCBI chr 6:115,817,658...115,830,361
Ensembl chr 6:115,817,658...115,830,332 		JBrowse link
G Mre11a MRE11A homolog A, double strand break repair nuclease involved_in
acts_upstream_of_or_within		 IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:2683367|PMID:14690604)		 GO_Central
MGI		 PMID:14690604 PMID:21873635 MGI:2683367 MGI:6201960 NCBI chr 9:14,695,971...14,748,421
Ensembl chr 9:14,695,950...14,748,419 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:50,065,678...50,090,943
Ensembl chr11:50,065,271...50,090,942 		JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within		 ISO
IMP
IBA		 (MGI:3805397|PMID:18614044)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:18614044 PMID:21873635 GO_REF:0000096 MGI:3805397 MGI:4834177 MGI:6201960 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:15,671,760...15,680,033
Ensembl chr 7:15,670,108...15,679,999 		JBrowse link
G Plk1 polo like kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096 		JBrowse link
G Rint1 RAD50 interactor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:23,992,700...24,028,582
Ensembl chr 5:23,992,709...24,025,367 		JBrowse link
G Syf2 SYF2 homolog, RNA splicing factor (S. cerevisiae) acts_upstream_of_or_within IMP (MGI:5435138|PMID:22448250) MGI PMID:22448250 MGI:5435138 NCBI chr 4:134,658,291...134,664,848
Ensembl chr 4:134,658,209...134,664,859 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:77,419,988...77,516,185
Ensembl chr11:77,419,988...77,498,641 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:126,464,848...126,485,468
Ensembl chr 7:126,464,850...126,483,875 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:117,258,180...117,413,283
Ensembl chr 5:117,258,194...117,413,284 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:79,309,944...79,347,896
Ensembl chr 7:79,309,944...79,347,896 		JBrowse link
G Topbp1 topoisomerase (DNA) II binding protein 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:103,182,351...103,227,627
Ensembl chr 9:103,182,414...103,227,627 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:36,569,764...36,582,896
Ensembl chr17:36,569,765...36,583,139 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:55,175,693...55,248,176
Ensembl chr13:55,175,693...55,248,113 		JBrowse link
mitotic intra-S DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983 		JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:94,535,798...94,544,611
Ensembl chr11:94,535,822...94,544,790 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:25,111,126...25,114,061
Ensembl chr17:25,107,460...25,114,061 		JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191 		JBrowse link
G Hus1b HUS1 checkpoint clamp component B involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr13:31,130,559...31,131,744
Ensembl chr13:31,130,556...31,131,742 		JBrowse link
G Mre11a MRE11A homolog A, double strand break repair nuclease involved_in
acts_upstream_of_or_within		 IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:2683367|PMID:14690604), (MGI:3805397|PMID:18614044)		 GO_Central
MGI		 PMID:14690604 PMID:18614044 PMID:21873635 MGI:2683367 MGI:3805397 MGI:6201960 NCBI chr 9:14,695,971...14,748,421
Ensembl chr 9:14,695,950...14,748,419 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within IGI (MGI:3512823|PMID:15533840) MGI PMID:15533840 MGI:3512823 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430 		JBrowse link
G Nek11 NIMA (never in mitosis gene a)-related expressed kinase 11 involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:105,039,355...105,272,723
Ensembl chr 9:105,039,355...105,272,723 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:100,753,672...100,787,569
Ensembl chr13:100,753,672...100,787,559 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within
involved_in		 IGI
IBA		 (MGI:1289930|PMID:9766521)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:9766521 PMID:21873635 MGI:1289930 MGI:6201960 NCBI chr19:4,245,195...4,251,710
Ensembl chr19:4,245,195...4,251,661 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296 		JBrowse link
G Tipin timeless interacting protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:64,188,776...64,212,704
Ensembl chr 9:64,188,863...64,212,706 		JBrowse link
G Xpc xeroderma pigmentosum, complementation group C acts_upstream_of_or_within IGI (MGI:3512823|PMID:15533840) MGI PMID:15533840 MGI:3512823 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870 		JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696 		JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO RGD
MGI		 PMID:20637979 GO_REF:0000096 MGI:4417868 RGD:10401658 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Ddx39b DEAD box helicase 39b involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683 		JBrowse link
G Thoc1 THO complex 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:9,958,176...9,995,486
Ensembl chr18:9,957,906...9,995,489 		JBrowse link
G Thoc5 THO complex 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:4,845,339...4,878,867
Ensembl chr11:4,845,320...4,878,867 		JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:36,227,404...36,243,175
Ensembl chr17:36,227,326...36,243,175 		JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle activator and apoptosis regulator 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:70,375,617...70,391,272
Ensembl chr14:70,375,613...70,391,260 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:72,115,970...72,272,954
Ensembl chr 2:72,115,981...72,272,954 		JBrowse link
regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Babam2 BRISC and BRCA1 A complex member 2 involved_in NAS (MGI:6867316|PMID:14636569) ComplexPortal PMID:14636569 MGI:6867316 NCBI chr 5:31,855,394...32,242,083
Ensembl chr 5:31,855,028...32,242,306 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 involved_in NAS (MGI:6867316|PMID:14636569) ComplexPortal PMID:14636569 MGI:6867316 NCBI chr 1:71,066,690...71,142,300
Ensembl chr 1:71,066,657...71,142,305 		JBrowse link
G Brca1 breast cancer 1, early onset involved_in NAS (MGI:6867316|PMID:14636569) ComplexPortal PMID:14636569 MGI:6867316 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Brca2 breast cancer 2, early onset involved_in NAS (MGI:6867316|PMID:14636569) ComplexPortal PMID:14636569 MGI:6867316 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 involved_in NAS (MGI:6867316|PMID:14636569) ComplexPortal PMID:14636569 MGI:6867316 NCBI chr  X:74,460,234...74,499,307
Ensembl chr  X:74,460,234...74,497,607 		JBrowse link
G Cry1 cryptochrome 1 (photolyase-like) involved_in IDA (MGI:5567851|PMID:24489120) UniProt PMID:24489120 MGI:5567851 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928 		JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within IMP (MGI:3850765|PMID:19481525) MGI PMID:19481525 MGI:3850765 NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940 		JBrowse link
G Etaa1 Ewing tumor-associated antigen 1 involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:17,888,753...17,903,875
Ensembl chr11:17,888,756...17,903,875 		JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within IMP (MGI:5299398|PMID:21911473) MGI PMID:21911473 MGI:5299398 NCBI chr15:3,993,046...4,009,055
Ensembl chr15:3,994,927...4,009,055 		JBrowse link
G Fem1b fem 1 homolog b involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:62,699,106...62,718,930
Ensembl chr 9:62,699,103...62,719,216 		JBrowse link
G Nek1 NIMA (never in mitosis gene a)-related expressed kinase 1 involved_in IMP (MGI:5619475|PMID:18843199) CACAO PMID:18843199 MGI:5619475 NCBI chr 8:61,446,184...61,584,383
Ensembl chr 8:61,446,229...61,584,380 		JBrowse link
G Rad51 RAD51 recombinase involved_in NAS (MGI:6867316|PMID:14636569) ComplexPortal PMID:14636569 MGI:6867316 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:111,997,576...112,026,854
Ensembl chr 8:111,997,576...112,026,854 		JBrowse link
G Rnaseh2b ribonuclease H2, subunit B acts_upstream_of_or_within IMP (MGI:5435090|PMID:22802351) MGI PMID:22802351 MGI:5435090 NCBI chr14:62,569,517...62,610,445
Ensembl chr14:62,530,038...62,610,441 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063 		JBrowse link
G Wdr76 WD repeat domain 76 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:121,337,204...121,375,341
Ensembl chr 2:121,337,204...121,375,341 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28775
    cellular process 16712
      signal transduction 6764
        intracellular signal transduction 2812
          signal transduction in response to DNA damage 189
            DNA damage checkpoint signaling 127
              mitotic DNA damage checkpoint signaling + 81
              negative regulation of DNA damage checkpoint + 6
              positive regulation of DNA damage checkpoint + 2
              regulation of DNA damage checkpoint + 24
Path 2
Term Annotations click to browse term
  biological_process 28775
    biological regulation 13394
      regulation of biological process 12980
        negative regulation of biological process 6091
          negative regulation of cellular process 4665
            negative regulation of cell cycle 424
              negative regulation of cell cycle process 336
                negative regulation of cell cycle phase transition 282
                  cell cycle checkpoint signaling 197
                    DNA integrity checkpoint signaling 135
                      DNA damage checkpoint signaling 127
                        mitotic DNA damage checkpoint signaling + 81
                        negative regulation of DNA damage checkpoint + 6
                        positive regulation of DNA damage checkpoint + 2
                        regulation of DNA damage checkpoint + 24
paths to the root