Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:cell cycle checkpoint signaling
go back to main search page
Accession:GO:0000075 term browser browse the term
Definition:A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
Comment:This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.
Synonyms:exact_synonym: cell cycle checkpoint;   signal transduction involved in G2/M transition checkpoint;   signal transduction involved in cell cycle checkpoint
 narrow_synonym: G1/S checkpoint;   G1/S transition checkpoint;   G2/M checkpoint;   G2/M transition checkpoint
 alt_id: GO:0031576;   GO:0071779;   GO:0072395;   GO:0072404;   GO:0072407
 xref: Wikipedia:Cell_cycle_checkpoint

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chrNW_004955460:9,340,728...9,672,478
Ensembl chrNW_004955460:9,340,681...9,672,134 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) UniProt PMID:18022368 NCBI chrNW_004955437:9,423,630...9,433,357 JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chrNW_004955477:10,982,530...11,002,747
Ensembl chrNW_004955477:10,999,168...11,002,651 		JBrowse link
DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within		 ISO (PMID:30886146)
(PMID:12937170)		 UniProt
MGI		 PMID:12937170 PMID:30886146 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Atr ATR serine/threonine kinase involved_in
acts_upstream_of_or_within		 ISO (PMID:14657349), (PMID:21705319), (PMID:21777809)
(PMID:12937170)		 UniProt
MGI		 PMID:12937170 PMID:14657349 PMID:21705319 PMID:21777809 NCBI chrNW_004955508:3,337,036...3,440,313
Ensembl chrNW_004955508:3,337,432...3,440,257 		JBrowse link
G Cdc5l cell division cycle 5 like involved_in ISO (PMID:24332808) UniProt PMID:24332808 NCBI chrNW_004955437:9,990,613...10,032,034
Ensembl chrNW_004955437:9,990,613...10,032,034 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:16963448)
(PMID:10859164)
(PMID:12529385)
(PMID:19716789)		 UniProt
MGI		 PMID:10859164 PMID:12529385 PMID:16963448 PMID:19716789 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Chek2 checkpoint kinase 2 ISO RGD PMID:10435585 RGD:633752 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173 		JBrowse link
G Clock clock circadian regulator involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004955447:15,394,496...15,537,969
Ensembl chrNW_004955447:15,454,630...15,530,906 		JBrowse link
G Clspn claspin involved_in ISO (PMID:16963448) UniProt PMID:16963448 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:28525742) UniProt PMID:28525742 NCBI chrNW_004955427:21,806,170...21,812,701
Ensembl chrNW_004955427:21,806,192...21,815,031 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO (PMID:12717439) UniProt PMID:12717439 NCBI chrNW_004955422:27,638,625...27,643,261
Ensembl chrNW_004955422:27,633,827...27,642,241 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) UniProt PMID:25820262 NCBI chrNW_004955556:745,175...812,215
Ensembl chrNW_004955556:748,231...813,133 		JBrowse link
G Gnb1l G protein subunit beta 1 like involved_in ISO (PMID:37541219) UniProt PMID:37541219 NCBI chrNW_004955442:18,224,081...18,281,558 JBrowse link
G Hinfp histone H4 transcription factor involved_in ISO (PMID:17974976) UniProt PMID:17974976 NCBI chrNW_004955412:20,236,607...20,247,288
Ensembl chrNW_004955412:20,242,317...20,249,456 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in
acts_upstream_of_or_within		 ISO (PMID:21659603)
(PMID:12529385)		 UniProt
MGI		 PMID:12529385 PMID:21659603 NCBI chrNW_004955456:5,465,180...5,476,380
Ensembl chrNW_004955456:5,465,182...5,474,303 		JBrowse link
G Ints7 integrator complex subunit 7 involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004955406:5,299,696...5,371,496
Ensembl chrNW_004955406:5,299,697...5,371,896 		JBrowse link
G LOC102025775 histone H2AX involved_in
NOT|acts_upstream_of_or_within		 ISO (PMID:17974976)
(PMID:11934988)		 UniProt
MGI		 PMID:11934988 PMID:17974976 NCBI chrNW_004955412:20,203,173...20,204,714
Ensembl chrNW_004955412:20,203,772...20,204,203 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:10891478) UniProt PMID:10891478 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) UniProt PMID:11836244 NCBI chrNW_004955449:1,976,186...2,139,044 JBrowse link
G Mapk14 mitogen-activated protein kinase 14 acts_upstream_of_or_within ISO (PMID:12937170) MGI PMID:12937170 NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083 		JBrowse link
G Nbn nibrin acts_upstream_of_or_within ISO (PMID:12529385) MGI PMID:12529385 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Parp9 poly(ADP-ribose) polymerase family member 9 involved_in ISO (PMID:28525742) UniProt PMID:28525742 NCBI chrNW_004955427:21,770,158...21,806,091
Ensembl chrNW_004955427:21,770,577...21,804,717 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISO (PMID:24332808) UniProt PMID:24332808 NCBI chrNW_004955511:5,546,212...5,552,368
Ensembl chrNW_004955511:5,545,989...5,557,792 		JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 acts_upstream_of_or_within ISO (PMID:12937170) MGI PMID:12937170 NCBI chrNW_004955482:8,934,734...9,031,230
Ensembl chrNW_004955482:8,934,306...9,035,203 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004955426:20,035,605...20,042,340
Ensembl chrNW_004955426:20,035,605...20,041,974 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in ISO (PMID:21659603) UniProt PMID:21659603 NCBI chrNW_004955422:18,079,634...18,146,122
Ensembl chrNW_004955422:18,079,652...18,085,548 		JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 involved_in ISO (PMID:21659603)
(PMID:25602520)		 UniProt PMID:21659603 PMID:25602520 NCBI chrNW_004955429:18,408,121...18,415,832
Ensembl chrNW_004955429:18,408,117...18,415,832 		JBrowse link
G Rpa4 replication protein A4 involved_in ISO (PMID:19942684) UniProt PMID:19942684 NCBI chrNW_004955503:2,514,460...2,516,973 JBrowse link
G Tipin TIMELESS interacting protein acts_upstream_of_or_within ISO (PMID:17141802) MGI PMID:17141802 NCBI chrNW_004955450:9,259,838...9,279,479
Ensembl chrNW_004955450:9,262,717...9,279,401 		JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO (PMID:17384681) UniProt PMID:17384681 NCBI chrNW_004955462:8,921,678...8,939,785 JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:17575048), (PMID:21777809), (PMID:31135337) UniProt PMID:17575048 PMID:21777809 PMID:31135337 NCBI chrNW_004955501:4,907,687...4,974,995
Ensembl chrNW_004955501:4,908,137...4,976,453 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:18045533) MGI PMID:18045533 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO (PMID:30886146) UniProt PMID:30886146 NCBI chrNW_004955411:22,548,139...22,577,287
Ensembl chrNW_004955411:22,548,219...22,580,903 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955412:15,425,136...15,469,819
Ensembl chrNW_004955412:15,426,159...15,443,023 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chrNW_004955494:353,572...369,207
Ensembl chrNW_004955494:353,310...368,873 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) BHF-UCL PMID:15149599 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479 		JBrowse link
G E2f7 E2F transcription factor 7 involved_in ISO (PMID:22802528) UniProt PMID:22802528 NCBI chrNW_004955405:16,148,640...16,187,272
Ensembl chrNW_004955405:16,148,480...16,186,282 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chrNW_004955532:3,604,720...3,615,112
Ensembl chrNW_004955532:3,603,975...3,614,290 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chrNW_004955476:11,325,877...11,331,447
Ensembl chrNW_004955476:11,326,626...11,331,360 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) UniProt PMID:15626733 MGI:3580934 NCBI chrNW_004955450:3,654,854...3,692,057
Ensembl chrNW_004955450:3,656,498...3,692,406 		JBrowse link
G Ppp2r5c protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430 NCBI chrNW_004955538:1,233,511...1,363,956
Ensembl chrNW_004955538:1,276,083...1,361,639 		JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (PMID:23235459) UniProt PMID:23235459 NCBI chrNW_004955477:10,982,530...11,002,747
Ensembl chrNW_004955477:10,999,168...11,002,651 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chrNW_004955445:2,036,314...2,050,882
Ensembl chrNW_004955445:2,036,124...2,052,139 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)		 CAFA PMID:16213212 MGI:5882892 NCBI chrNW_004955467:8,519,760...8,525,514
Ensembl chrNW_004955467:8,519,760...8,527,182 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:16213212)
(PMID:16107883)		 CAFA
MGI		 PMID:16107883 PMID:16213212 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:14672932)
(MGI:2388867|PMID:12192004)		 UniProt PMID:12192004 PMID:14672932 MGI:2388867 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102 		JBrowse link
G Clspn claspin acts_upstream_of_or_within ISO (PMID:12766152)
(PMID:16123041)		 MGI
UniProt		 PMID:12766152 PMID:16123041 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO (PMID:22570476) UniProt PMID:22570476 NCBI chrNW_004955425:20,664,412...20,705,070
Ensembl chrNW_004955425:20,661,727...20,702,754 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 involved_in ISO (PMID:21482717) UniProt PMID:21482717 NCBI chrNW_004955583:688,288...722,393 JBrowse link
G Tipin TIMELESS interacting protein involved_in ISO (PMID:17102137) HGNC-UCL PMID:17102137 NCBI chrNW_004955450:9,259,838...9,279,479
Ensembl chrNW_004955450:9,262,717...9,279,401 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:21482717), (PMID:21777809) UniProt PMID:21482717 PMID:21777809 NCBI chrNW_004955501:4,907,687...4,974,995
Ensembl chrNW_004955501:4,908,137...4,976,453 		JBrowse link
meiotic cell cycle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsun2 NOP2/Sun RNA methyltransferase 2 involved_in ISO (MGI:5525987|PMID:23401851) CACAO PMID:23401851 MGI:5525987 NCBI chrNW_004955504:4,339,044...4,360,176
Ensembl chrNW_004955504:4,338,855...4,361,520 		JBrowse link
meiotic recombination checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hormad1 HORMA domain containing 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:4868505|PMID:21079677), (MGI:5009722|PMID:21478856)
(PMID:22530760)		 UniProt
MGI		 PMID:21079677 PMID:21478856 PMID:22530760 MGI:4868505 MGI:5009722 NCBI chrNW_004955413:130,214...155,381
Ensembl chrNW_004955413:132,711...152,720 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO (PMID:9716408) UniProt PMID:9716408 NCBI chrNW_004955426:20,035,605...20,042,340
Ensembl chrNW_004955426:20,035,605...20,041,974 		JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk TTK protein kinase acts_upstream_of_or_within ISO (PMID:21558374) MGI PMID:21558374 NCBI chrNW_004955502:7,824,194...7,866,879 JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:10935642) UniProt PMID:10935642 NCBI chrNW_004955482:233,485...267,064
Ensembl chrNW_004955482:233,486...267,064 		JBrowse link
mitotic cytokinesis checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp4c charged multivesicular body protein 4C involved_in ISO (PMID:22422861), (PMID:24814515) UniProt PMID:22422861 PMID:24814515 NCBI chrNW_004955417:96,674...135,601
Ensembl chrNW_004955417:96,865...137,739 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:24814515) UniProt PMID:24814515 NCBI chrNW_004955484:7,368,938...7,375,964
Ensembl chrNW_004955484:7,368,938...7,375,969 		JBrowse link
G Zfyve19 zinc finger FYVE-type containing 19 involved_in ISO (PMID:24814515) UniProt PMID:24814515 NCBI chrNW_004955416:7,672,499...7,679,851
Ensembl chrNW_004955416:7,672,592...7,679,632 		JBrowse link
mitotic DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Znf830 zinc finger protein 830 acts_upstream_of_or_within ISO (PMID:23213458) MGI PMID:23213458 NCBI chrNW_004955481:9,661,791...9,663,326
Ensembl chrNW_004955481:9,661,830...9,662,918 		JBrowse link
mitotic DNA integrity checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102020128 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:18790802) UniProt PMID:18790802 NCBI chrNW_004955421:9,066,906...9,080,352 JBrowse link
mitotic DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clspn claspin involved_in ISO (PMID:16885022) UniProt PMID:16885022 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 involved_in ISO (PMID:10722740) UniProt PMID:10722740 NCBI chrNW_004955433:23,333,797...23,358,255
Ensembl chrNW_004955433:23,333,742...23,358,579 		JBrowse link
G Znf830 zinc finger protein 830 involved_in ISO (MGI:4950701|PMID:21191184) UniProt PMID:21191184 MGI:4950701 NCBI chrNW_004955481:9,661,791...9,663,326
Ensembl chrNW_004955481:9,661,830...9,662,918 		JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 involved_in ISO (PMID:19412162) UniProt PMID:19412162 NCBI chrNW_004955422:16,449,921...16,462,676
Ensembl chrNW_004955422:16,448,770...16,463,300 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (PMID:16286473) UniProt PMID:16286473 NCBI chrNW_004955422:1,658,237...1,687,000
Ensembl chrNW_004955422:1,657,926...1,695,404 		JBrowse link
G Fbxo31 F-box protein 31 involved_in ISO (PMID:19412162) UniProt PMID:19412162 NCBI chrNW_004955541:1,811,010...1,828,734
Ensembl chrNW_004955541:1,811,010...1,828,724 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within ISO (PMID:19744960) MGI PMID:19744960 NCBI chrNW_004955453:3,201,593...3,301,541
Ensembl chrNW_004955453:3,203,358...3,301,547 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:21731742) UniProt PMID:21731742 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:20173098) UniProt PMID:20173098 NCBI chrNW_004955484:2,824,057...2,857,321
Ensembl chrNW_004955484:2,824,422...2,858,283 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO (PMID:21731742) UniProt PMID:21731742 NCBI chrNW_004955452:7,080,641...7,098,009
Ensembl chrNW_004955452:7,080,579...7,097,742 		JBrowse link
G Rps27l ribosomal protein S27 like involved_in ISO (PMID:18056458) UniProt PMID:18056458 NCBI chrNW_004955450:12,122,948...12,126,167
Ensembl chrNW_004955450:12,122,921...12,128,101 		JBrowse link
G Sde2 SDE2 telomere maintenance homolog involved_in ISO (PMID:27906959) UniProt PMID:27906959 NCBI chrNW_004955489:181,425...210,966
Ensembl chrNW_004955489:180,414...210,900 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:7958916)
(PMID:16107883)		 BHF-UCL
MGI		 PMID:7958916 PMID:16107883 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:23993650)
(PMID:18045533)		 MGI PMID:18045533 PMID:23993650 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:21329877) UniProt PMID:21329877 NCBI chrNW_004955462:2,358,842...2,435,644
Ensembl chrNW_004955462:2,358,842...2,435,628 		JBrowse link
mitotic G1/S transition checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo like kinase 3 involved_in ISO (MGI:5142362|PMID:21376736) UniProt PMID:21376736 MGI:5142362 NCBI chrNW_004955464:13,419,562...13,424,104
Ensembl chrNW_004955464:13,419,562...13,424,104 		JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004955474:6,252,321...6,265,518
Ensembl chrNW_004955474:6,252,321...6,265,286 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:15149599) BHF-UCL PMID:15149599 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISO (PMID:19261746), (PMID:19261748), (PMID:19261749) UniProt PMID:19261746 PMID:19261748 PMID:19261749 NCBI chrNW_004955524:939,250...944,457
Ensembl chrNW_004955524:937,815...944,456 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO (PMID:19261748) UniProt PMID:19261748 NCBI chrNW_004955469:9,831,488...10,246,631
Ensembl chrNW_004955469:9,831,488...10,246,899 		JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) UniProt PMID:11309417 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProt PMID:17525341 PMID:19261746 PMID:19261748 NCBI chrNW_004955594:551,407...613,772
Ensembl chrNW_004955594:554,081...613,661 		JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO (PMID:15150265) UniProt PMID:15150265 NCBI chrNW_004955567:924,728...943,092
Ensembl chrNW_004955567:924,734...943,701 		JBrowse link
G Ccng1 cyclin G1 ISO RGD PMID:9464250 RGD:2316029 NCBI chrNW_004955408:16,846,050...16,850,365 JBrowse link
G Cdc14b cell division cycle 14B involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955422:23,303,472...23,445,785
Ensembl chrNW_004955422:23,303,250...23,322,493 		JBrowse link
G Cdk1 cyclin dependent kinase 1 acts_upstream_of_or_within ISO (PMID:12937170) MGI PMID:12937170 NCBI chrNW_004955425:14,210,681...14,226,474
Ensembl chrNW_004955425:14,210,680...14,226,474 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:15790566) UniProt PMID:15790566 NCBI chrNW_004955451:13,160,811...13,170,012
Ensembl chrNW_004955451:13,120,761...13,170,073 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) UniProt PMID:23213251 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:20932473) UniProt PMID:20932473 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Clspn claspin involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955422:1,702,131...1,734,603
Ensembl chrNW_004955422:1,700,692...1,734,773 		JBrowse link
G CUNH10orf90 chromosome unknown C10orf90 homolog involved_in ISO (MGI:4455105|PMID:20154723) UniProt PMID:20154723 MGI:4455105 NCBI chrNW_004955477:4,299,277...4,510,702
Ensembl chrNW_004955477:4,297,588...4,510,959 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO (PMID:17085480) UniProt PMID:17085480 NCBI chrNW_004955406:5,256,057...5,299,573
Ensembl chrNW_004955406:5,254,558...5,299,573 		JBrowse link
G Foxn3 forkhead box N3 involved_in ISO (PMID:9154802) UniProt PMID:9154802 NCBI chrNW_004955438:11,720,563...12,126,185
Ensembl chrNW_004955438:11,720,570...12,126,185 		JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within ISO (PMID:12048180) MGI PMID:12048180 NCBI chrNW_004955475:10,666,024...10,673,717
Ensembl chrNW_004955475:10,665,987...10,674,110 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955495:5,481,914...5,503,690
Ensembl chrNW_004955495:5,481,916...5,505,521 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:20467439) MGI PMID:20467439 NCBI chrNW_004955583:730,353...731,301
Ensembl chrNW_004955583:730,289...731,260 		JBrowse link
G Mbd4 methyl-CpG binding domain 4, DNA glycosylase acts_upstream_of_or_within ISO (PMID:14614141) MGI PMID:14614141 NCBI chrNW_004955429:17,858,656...17,868,111
Ensembl chrNW_004955429:17,858,937...17,869,262 		JBrowse link
G Mbtps1 membrane bound transcription factor peptidase, site 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955564:176,230...226,555
Ensembl chrNW_004955564:176,230...228,587 		JBrowse link
G Mbtps2 membrane bound transcription factor peptidase, site 2 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955509:2,185,054...2,222,497
Ensembl chrNW_004955509:2,184,522...2,222,505 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chrNW_004955408:726,124...758,851 JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within		 ISO (PMID:11438675)
(PMID:18614044)		 UniProt
MGI		 PMID:11438675 PMID:18614044 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) UniProt PMID:21741933 NCBI chrNW_004955574:1,505,997...1,514,680
Ensembl chrNW_004955574:1,506,022...1,517,130 		JBrowse link
G Plk1 polo like kinase 1 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955493:2,206,353...2,217,231
Ensembl chrNW_004955493:2,206,353...2,217,231 		JBrowse link
G Rint1 RAD50 interactor 1 involved_in ISO (PMID:11096100) BHF-UCL PMID:11096100 NCBI chrNW_004955410:10,121,322...10,144,748
Ensembl chrNW_004955410:10,121,219...10,144,748 		JBrowse link
G Syf2 SYF2 pre-mRNA splicing factor acts_upstream_of_or_within ISO (PMID:22448250) MGI PMID:22448250 NCBI chrNW_004955452:4,850,049...4,856,647
Ensembl chrNW_004955452:4,848,659...4,857,114 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955481:3,698,686...3,836,209
Ensembl chrNW_004955481:3,705,202...3,772,116 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955493:6,968,537...6,986,608
Ensembl chrNW_004955493:6,969,096...6,985,878 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955455:13,020,618...13,207,539
Ensembl chrNW_004955455:13,103,357...13,211,315 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 NCBI chrNW_004955408:29,154,373...29,274,817
Ensembl chrNW_004955408:29,154,629...29,274,856 		JBrowse link
mitotic G2/M transition checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase involved_in ISO (PMID:30139873) UniProt PMID:30139873 NCBI chrNW_004955508:3,337,036...3,440,313
Ensembl chrNW_004955508:3,337,432...3,440,257 		JBrowse link
G Brca1 BRCA1 DNA repair associated acts_upstream_of_or_within ISO (PMID:15254237) MGI PMID:15254237 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:19223857) UniProt PMID:19223857 NCBI chrNW_004955451:13,160,811...13,170,012
Ensembl chrNW_004955451:13,120,761...13,170,073 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:33108758)
(PMID:9278511)		 UniProt PMID:9278511 PMID:33108758 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:18172500), (PMID:19182791) UniProt PMID:18172500 PMID:19182791 NCBI chrNW_004955482:233,485...267,064
Ensembl chrNW_004955482:233,486...267,064 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:30139873) UniProt PMID:30139873 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007 		JBrowse link
G Inip INTS3 and NABP interacting protein involved_in ISO (PMID:19683501) ComplexPortal PMID:19683501 NCBI chrNW_004955419:14,729,275...14,732,971
Ensembl chrNW_004955419:14,728,816...14,732,971 		JBrowse link
G Ints3 integrator complex subunit 3 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955545:352,170...394,751
Ensembl chrNW_004955545:351,872...396,052 		JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955403:7,603,002...7,610,925
Ensembl chrNW_004955403:7,604,144...7,611,042 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955458:3,835,205...3,836,841
Ensembl chrNW_004955458:3,835,205...3,840,634 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO (PMID:33108758) UniProt PMID:33108758 NCBI chrNW_004955434:4,250,105...4,251,508 JBrowse link
mitotic intra-S DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO (PMID:15916964) UniProt PMID:15916964 NCBI chrNW_004955449:332,563...411,218
Ensembl chrNW_004955449:338,193...411,218 		JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO (PMID:11298456) UniProt PMID:11298456 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:15533840) MGI PMID:15533840 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Nek11 NIMA related kinase 11 involved_in ISO (PMID:15161910) UniProt PMID:15161910 NCBI chrNW_004955501:7,107,858...7,375,079
Ensembl chrNW_004955501:7,108,526...7,374,984 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO (PMID:15538388) UniProt PMID:15538388 NCBI chrNW_004955575:78,686...115,072
Ensembl chrNW_004955575:78,335...115,129 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO (PMID:9766521) MGI PMID:9766521 NCBI chrNW_004955422:18,079,634...18,146,122
Ensembl chrNW_004955422:18,079,652...18,085,548 		JBrowse link
G Tipin TIMELESS interacting protein involved_in ISO (PMID:17102137) HGNC-UCL PMID:17102137 NCBI chrNW_004955450:9,259,838...9,279,479
Ensembl chrNW_004955450:9,262,717...9,279,401 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor acts_upstream_of_or_within ISO (PMID:15533840) MGI PMID:15533840 NCBI chrNW_004955429:16,935,901...16,968,285
Ensembl chrNW_004955429:16,935,901...16,955,845 		JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:17227893) MGI PMID:17227893 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:11943150) UniProt PMID:11943150 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase involved_in ISO (PMID:18995837) UniProt PMID:18995837 NCBI chrNW_004955470:3,152,798...3,190,185
Ensembl chrNW_004955470:3,152,758...3,191,888 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B involved_in ISO (PMID:10477750)
(PMID:20220147)		 UniProt PMID:10477750 PMID:20220147 NCBI chrNW_004955416:7,105,302...7,159,121
Ensembl chrNW_004955416:7,105,261...7,160,012 		JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chrNW_004955496:5,468,759...5,514,915
Ensembl chrNW_004955496:5,469,239...5,513,574 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO (PMID:23071153) UniProt PMID:23071153 NCBI chrNW_004955467:13,099,958...13,104,337
Ensembl chrNW_004955467:13,078,346...13,104,241 		JBrowse link
G Ik IK cytokine involved_in ISO (PMID:22351768) UniProt PMID:22351768 NCBI chrNW_004955418:39,695...52,862
Ensembl chrNW_004955418:39,695...52,862 		JBrowse link
G Klhl22 kelch like family member 22 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chrNW_004955442:19,010,971...19,051,300
Ensembl chrNW_004955442:19,009,155...19,051,393 		JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO (PMID:11146660) UniProt PMID:11146660 NCBI chrNW_004955482:6,040,964...6,119,814
Ensembl chrNW_004955482:6,043,456...6,115,816 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:18981471)
(PMID:36322655), (PMID:9546394)		 UniProt PMID:9546394 PMID:18981471 PMID:36322655 NCBI chrNW_004955460:9,340,728...9,672,478
Ensembl chrNW_004955460:9,340,681...9,672,134 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:18981471)
(PMID:11201745)		 UniProt
MGI		 PMID:11201745 PMID:18981471 NCBI chrNW_004955428:20,421,718...20,443,394
Ensembl chrNW_004955428:20,421,723...20,430,307 		JBrowse link
G Plk1 polo like kinase 1 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chrNW_004955493:2,206,353...2,217,231
Ensembl chrNW_004955493:2,206,353...2,217,231 		JBrowse link
G Psmg2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (PMID:12147697) MGI PMID:12147697 NCBI chrNW_004955402:857,228...870,940
Ensembl chrNW_004955402:857,432...869,983 		JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor involved_in ISO (MGI:5318128|PMID:22405274) UniProt PMID:22405274 MGI:5318128 NCBI chrNW_004955451:4,206,114...4,296,969
Ensembl chrNW_004955451:4,179,591...4,297,024 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO (PMID:20133940) UniProt PMID:20133940 NCBI chrNW_004955406:24,742,525...24,805,989
Ensembl chrNW_004955406:24,742,525...24,805,989 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO (PMID:28553959) UniProt PMID:28553959 NCBI chrNW_004955504:434,187...452,636
Ensembl chrNW_004955504:434,159...452,671 		JBrowse link
G Ttk TTK protein kinase involved_in ISO (PMID:25197064) MGI PMID:25197064 NCBI chrNW_004955502:7,824,194...7,866,879 JBrowse link
G Znf207 zinc finger protein 207 involved_in ISO (PMID:24462186), (PMID:24462187) UniProt PMID:24462186 PMID:24462187 NCBI chrNW_004955481:7,307,520...7,325,591
Ensembl chrNW_004955481:7,307,521...7,328,198 		JBrowse link
G Zw10 zw10 kinetochore protein involved_in ISO (PMID:11146660)
(PMID:15824131)		 UniProt PMID:11146660 PMID:15824131 NCBI chrNW_004955412:15,354,918...15,391,233
Ensembl chrNW_004955412:15,350,285...15,391,996 		JBrowse link
G Zwilch zwilch kinetochore protein involved_in ISO (PMID:15824131) UniProt PMID:15824131 NCBI chrNW_004955450:9,139,214...9,170,136
Ensembl chrNW_004955450:9,139,169...9,169,921 		JBrowse link
G Zwint ZW10 interacting kinetochore protein involved_in ISO (PMID:15485811) HGNC-UCL PMID:15485811 NCBI chrNW_004955425:10,477,224...10,486,372
Ensembl chrNW_004955425:10,477,331...10,486,288 		JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:23728299) UniProt PMID:23728299 NCBI chrNW_004955495:7,959,033...7,989,216
Ensembl chrNW_004955495:7,957,510...7,988,498 		JBrowse link
G Chek2 checkpoint kinase 2 ISO RGD PMID:20637979 RGD:10401658 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173 		JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1 regulatory subunit 10 involved_in ISO (PMID:23426265) BHF-UCL PMID:23426265 NCBI chrNW_004955583:621,380...635,595
Ensembl chrNW_004955583:621,092...634,929 		JBrowse link
positive regulation of cell cycle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO (PMID:21040746) MGI PMID:21040746 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555 		JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) UniProt PMID:23352644 NCBI chrNW_004955403:46,027,997...46,042,154
Ensembl chrNW_004955403:46,027,998...46,042,154 		JBrowse link
G Tti1 TELO2 interacting protein 1 involved_in ISO (PMID:36724785) UniProt PMID:36724785 NCBI chrNW_004955445:18,676,285...18,729,512
Ensembl chrNW_004955445:18,675,434...18,729,512 		JBrowse link
positive regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 involved_in ISO (MGI:7356173|PMID:35167144) UniProt PMID:35167144 MGI:7356173 NCBI chrNW_004955416:7,498,983...7,561,620
Ensembl chrNW_004955416:7,500,415...7,562,273 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO (PMID:19229290) UniProt PMID:19229290 NCBI chrNW_004955620:46,535...82,595
Ensembl chrNW_004955620:46,556...82,595 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668) UniProt PMID:23108668 NCBI chrNW_004955469:552,850...590,792
Ensembl chrNW_004955469:552,677...592,137 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:22898774)
(PMID:36322655)		 ComplexPortal
UniProt		 PMID:22898774 PMID:36322655 NCBI chrNW_004955460:9,340,728...9,672,478
Ensembl chrNW_004955460:9,340,681...9,672,134 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in ISO (PMID:20870947)
(PMID:22898774), (PMID:8824189)
(MGI:4839685|PMID:20870947)		 UniProt
ComplexPortal		 PMID:8824189 PMID:20870947 PMID:22898774 MGI:4839685 NCBI chrNW_004955428:20,421,718...20,443,394
Ensembl chrNW_004955428:20,421,723...20,430,307 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO (PMID:25743205) UniProt PMID:25743205 NCBI chrNW_004955402:7,692,009...7,728,876
Ensembl chrNW_004955402:7,691,937...7,729,690 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)		 UniProt PMID:20870947 MGI:4839685 NCBI chrNW_004955404:618,092...639,424
Ensembl chrNW_004955404:618,092...639,704 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO (PMID:18981471), (PMID:19273613) UniProt PMID:18981471 PMID:19273613 NCBI chrNW_004955406:24,742,525...24,805,989
Ensembl chrNW_004955406:24,742,525...24,805,989 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) UniProt PMID:23108668 NCBI chrNW_004955538:2,499,297...2,511,898
Ensembl chrNW_004955538:2,501,607...2,509,778 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:15342622) UniProt PMID:15342622 NCBI chrNW_004955449:1,976,186...2,139,044 JBrowse link
regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 involved_in ISO (MGI:5567851|PMID:24489120) UniProt PMID:24489120 MGI:5567851 NCBI chrNW_004955405:40,878,227...40,941,664
Ensembl chrNW_004955405:40,874,322...40,941,664 		JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO (PMID:19481525) MGI PMID:19481525 NCBI chrNW_004955404:583,261...617,914
Ensembl chrNW_004955404:583,261...617,914 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:27723717), (PMID:27723720) UniProt PMID:27723717 PMID:27723720 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007 		JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within ISO (PMID:21911473) MGI PMID:21911473 NCBI chrNW_004955426:26,046,742...26,066,747
Ensembl chrNW_004955426:26,046,742...26,063,388 		JBrowse link
G Fem1b fem-1 homolog B involved_in ISO (PMID:19330022) UniProt PMID:19330022 NCBI chrNW_004955450:7,834,487...7,847,334
Ensembl chrNW_004955450:7,834,487...7,847,334 		JBrowse link
G Nek1 NIMA related kinase 1 involved_in ISO (MGI:5619475|PMID:18843199) CACAO PMID:18843199 MGI:5619475 NCBI chrNW_004955403:36,710,248...36,878,901
Ensembl chrNW_004955403:36,720,162...36,881,891 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:21504906) UniProt PMID:21504906 NCBI chrNW_004955484:2,824,057...2,857,321
Ensembl chrNW_004955484:2,824,422...2,858,283 		JBrowse link
G Rnaseh2b ribonuclease H2 subunit B acts_upstream_of_or_within ISO (PMID:22802351) MGI PMID:22802351 NCBI chrNW_004955431:4,291,687...4,368,169
Ensembl chrNW_004955431:4,291,688...4,351,178 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO (PMID:21504906) UniProt PMID:21504906 NCBI chrNW_004955452:7,080,641...7,098,009
Ensembl chrNW_004955452:7,080,579...7,097,742 		JBrowse link
regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zwint ZW10 interacting kinetochore protein involved_in ISO (MGI:6215447|PMID:26486467) UniProt PMID:26486467 MGI:6215447 NCBI chrNW_004955425:10,477,224...10,486,372
Ensembl chrNW_004955425:10,477,331...10,486,288 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 involved_in ISO (PMID:21926987) UniProt PMID:21926987 NCBI chrNW_004955414:19,218,727...19,222,138
Ensembl chrNW_004955414:19,218,727...19,222,138 		JBrowse link
G Ccnb1 cyclin B1 involved_in ISO (PMID:18195732) BHF-UCL PMID:18195732 NCBI chrNW_004955446:140,661...149,500
Ensembl chrNW_004955446:140,093...149,500 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISO (PMID:19282672) UniProt PMID:19282672 NCBI chrNW_004955419:7,412,177...7,606,883
Ensembl chrNW_004955419:7,412,331...7,610,353 		JBrowse link
G Knl1 kinetochore scaffold 1 involved_in ISO (PMID:19893618) UniProt PMID:19893618 NCBI chrNW_004955416:7,498,983...7,561,620
Ensembl chrNW_004955416:7,500,415...7,562,273 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within ISO (PMID:17724024) MGI PMID:17724024 NCBI chrNW_004955493:3,440,832...3,499,658
Ensembl chrNW_004955493:3,431,578...3,502,066 		JBrowse link
G Prp4k pre-mRNA processing factor kinase PRP4K involved_in ISO (PMID:17998396) UniProt PMID:17998396 NCBI chrNW_004955465:9,359,634...9,392,913
Ensembl chrNW_004955465:9,359,634...9,392,913 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (MGI:5448515|PMID:21853124) UniProt PMID:21853124 MGI:5448515 NCBI chrNW_004955405:31,977,045...32,006,733
Ensembl chrNW_004955405:31,977,602...32,006,810 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    cellular process 11505
      signal transduction 3939
        intracellular signal transduction 2106
          cell cycle checkpoint signaling 153
            DNA integrity checkpoint signaling + 108
            meiotic cell cycle checkpoint signaling + 7
            mitotic cell cycle checkpoint signaling + 116
            negative regulation of cell cycle checkpoint + 6
            positive regulation of cell cycle checkpoint + 13
            regulation of cell cycle checkpoint + 34
            spindle checkpoint signaling + 36
Path 2
Term Annotations click to browse term
  biological_process 12321
    biological regulation 8863
      regulation of biological process 8603
        negative regulation of biological process 4690
          negative regulation of cellular process 4380
            negative regulation of cell cycle 313
              negative regulation of cell cycle process 254
                negative regulation of cell cycle phase transition 208
                  cell cycle checkpoint signaling 153
                    DNA integrity checkpoint signaling + 108
                    meiotic cell cycle checkpoint signaling + 7
                    mitotic cell cycle checkpoint signaling + 116
                    negative regulation of cell cycle checkpoint + 6
                    positive regulation of cell cycle checkpoint + 13
                    regulation of cell cycle checkpoint + 34
                    spindle checkpoint signaling + 36
paths to the root