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ONTOLOGY REPORT - ANNOTATIONS


Term:very long-chain fatty acid metabolic process
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Accession:GO:0000038 term browser browse the term
Definition:The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:exact_synonym: very-long-chain fatty acid metabolism


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very long-chain fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 involved_in ISO (PMID:29397936)
(PMID:15489218)
UniProt PMID:15489218 PMID:29397936 NCBI chr  X:128,152,697...128,171,007 JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in ISO PMID:21209459
(PMID:10196381), (PMID:29397936)
UniProt PMID:10196381 PMID:21209459 PMID:29397936 RGD:127285396 NCBI chr11:35,818,451...35,884,696 JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr11:35,866,928...35,884,503 JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:38,750,147...38,846,011
Ensembl chr20:38,748,787...38,845,989
JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,282,556...1,297,154
Ensembl chr15:1,282,650...1,297,832
JBrowse link
G ACOT4 acyl-CoA thioesterase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:50,806,736...50,811,294
Ensembl chr24:50,807,212...50,811,181
JBrowse link
G ACOX1 acyl-CoA oxidase 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr16:45,706,009...45,745,564
Ensembl chr16:45,706,360...45,740,247
JBrowse link
G ACOX2 acyl-CoA oxidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:19,805,736...19,838,399
Ensembl chr22:19,804,440...19,838,374
JBrowse link
G ACSBG1 acyl-CoA synthetase bubblegum family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:5,117,740...5,183,164
Ensembl chr26:5,117,818...5,185,418
JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 involved_in ISO PMID:8978480 UniProt PMID:8978480 RGD:14697720 NCBI chr 7:130,712,633...130,783,360
Ensembl chr 7:130,712,308...130,763,756
JBrowse link
G ELOVL2 ELOVL fatty acid elongase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11567032) MGI
Ensembl
PMID:11567032 GO_REF:0000107 NCBI chr17:61,099,153...61,159,213
Ensembl chr17:61,099,255...61,159,207
JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16484321) Ensembl
MGI
PMID:16484321 GO_REF:0000107 NCBI chr23:22,674,059...22,761,270
Ensembl chr23:22,674,072...22,762,056
JBrowse link
G PEX2 peroxisomal biogenesis factor 2 involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr 8:72,513,975...72,532,399
Ensembl chr 8:72,514,307...72,517,003
JBrowse link
G PEX5 peroxisomal biogenesis factor 5 acts_upstream_of_or_within ISO (PMID:10653000) MGI PMID:10653000 NCBI chr11:7,255,078...7,286,500
Ensembl chr11:7,256,182...7,274,938
JBrowse link
G SLC27A2 solute carrier family 27 member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12048192) MGI
Ensembl
PMID:12048192 GO_REF:0000107 NCBI chr26:33,080,844...33,134,467
Ensembl chr26:33,083,317...33,134,433
JBrowse link
G SLC27A4 solute carrier family 27 member 4 acts_upstream_of_or_within ISO (PMID:15653672), (PMID:17522045)
(PMID:17401141)
MGI PMID:15653672 PMID:17401141 PMID:17522045 NCBI chr12:9,769,242...9,788,214 JBrowse link
G SLC27A4 solute carrier family 27 member 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:9,769,974...9,786,464 JBrowse link
G SLC27A5 solute carrier family 27 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:50,782,713...50,793,816
Ensembl chr 6:50,781,544...50,792,515
JBrowse link
very long-chain fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,706,009...45,745,564
Ensembl chr16:45,706,360...45,740,247
JBrowse link
very long-chain fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELOVL1 ELOVL fatty acid elongase 1 involved_in ISO (PMID:20166112), (PMID:20937905) UniProt PMID:20166112 PMID:20937905 NCBI chr20:89,444,146...89,448,802 JBrowse link
G ELOVL2 ELOVL fatty acid elongase 2 involved_in IEA InterPro
Ensembl
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:61,099,153...61,159,213
Ensembl chr17:61,099,255...61,159,207
JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 involved_in IEA UniProt
TreeGrafter
InterPro
Ensembl
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:95,260,674...95,265,682
Ensembl chr 9:95,262,342...95,265,350
JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 involved_in IEA UniProt
Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr13:4,652,674...4,687,308
Ensembl chr13:4,652,677...4,687,294
JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 involved_in IEA UniProt
Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:19,227,209...19,305,789
Ensembl chr17:19,277,593...19,307,625
JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:57,949,910...58,095,637 JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA UniProt
Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:56,934,631...57,026,749
Ensembl chr 4:56,934,645...56,965,285
JBrowse link
G HACD1 3-hydroxyacyl-CoA dehydratase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:17,537,945...17,565,831
Ensembl chr 9:17,536,611...17,565,383
JBrowse link
G HACD2 3-hydroxyacyl-CoA dehydratase 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr22:57,285,948...57,379,894
Ensembl chr22:57,322,657...57,381,683
JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr26:18,002,618...18,050,302
Ensembl chr26:18,004,586...18,050,258
JBrowse link
G TECR trans-2,3-enoyl-CoA reductase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 6:13,186,972...13,224,908
Ensembl chr 6:13,188,450...13,227,776
JBrowse link
G TECRL trans-2,3-enoyl-CoA reductase like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:4,414,168...4,536,561
Ensembl chr 7:4,414,303...4,536,551
JBrowse link
very long-chain fatty acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:128,152,697...128,171,007 JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in ISO PMID:25043761
(PMID:18723473)
(PMID:21145416)
UniProt PMID:18723473 PMID:21145416 PMID:25043761 RGD:13673760 NCBI chr11:35,818,451...35,884,696 JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 Ensembl chr11:35,866,928...35,884,503 JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr20:38,750,147...38,846,011
Ensembl chr20:38,748,787...38,845,989
JBrowse link
G ABCD4 ATP binding cassette subfamily D member 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:51,497,440...51,516,919
Ensembl chr24:51,495,790...51,516,905
JBrowse link
G SLC27A2 solute carrier family 27 member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12719378) MGI
Ensembl
PMID:12719378 GO_REF:0000107 NCBI chr26:33,080,844...33,134,467
Ensembl chr26:33,083,317...33,134,433
JBrowse link
G SLC27A4 solute carrier family 27 member 4 acts_upstream_of_or_within ISO (PMID:17522045) MGI PMID:17522045 NCBI chr12:9,769,242...9,788,214 JBrowse link
G SLC27A4 solute carrier family 27 member 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:9,769,974...9,786,464 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17023
    cellular process 16537
      metabolic process 10906
        primary metabolic process 9686
          lipid metabolic process 1322
            fatty acid metabolic process 396
              very long-chain fatty acid metabolic process 30
                very long-chain fatty acid biosynthetic process 12
                very long-chain fatty acid catabolic process + 9
Path 2
Term Annotations click to browse term
  biological_process 17023
    cellular process 16537
      metabolic process 10906
        small molecule metabolic process 1725
          organic acid metabolic process 923
            oxoacid metabolic process 915
              carboxylic acid metabolic process 897
                monocarboxylic acid metabolic process 628
                  fatty acid metabolic process 396
                    very long-chain fatty acid metabolic process 30
                      very long-chain fatty acid biosynthetic process 12
                      very long-chain fatty acid catabolic process + 9
paths to the root