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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of ruffle assembly
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Accession:GO:1900027 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ruffle assembly.
Synonyms:exact_synonym: regulation of membrane ruffle formation;   regulation of membrane ruffling
 never_in_taxon: NCBITaxon:2 ! Bacteria;   NCBITaxon:33090 ! Viridiplantae;   NCBITaxon:4751 ! Fungi

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regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170 		JBrowse link
G Coro1c coronin 1C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:555,719...637,420
Ensembl chrNW_004936769:553,642...637,008 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23372835) Ensembl
MGI		 PMID:23372835 GO_REF:0000107 NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174 		JBrowse link
G P2rx4 purinergic receptor P2X 4 NOT|involved_in ISO PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chrNW_004936558:3,062,279...3,077,493
Ensembl chrNW_004936558:3,059,886...3,077,451 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:4,265,572...4,307,283
Ensembl chrNW_004936474:4,265,578...4,281,364 		JBrowse link
G Rdx radixin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:3,992,542...4,060,598
Ensembl chrNW_004936612:3,992,542...4,040,315 		JBrowse link
G Rhog ras homolog family member G involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23372835) Ensembl
MGI		 PMID:23372835 GO_REF:0000107 NCBI chrNW_004936498:1,077,354...1,088,003
Ensembl chrNW_004936498:1,077,422...1,088,003 		JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21624956) Ensembl
TreeGrafter
MGI		 PMID:21624956 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936532:101,571...127,331
Ensembl chrNW_004936532:99,215...127,493 		JBrowse link
G Wdpcp WD repeat containing planar cell polarity effector involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24302887) Ensembl
MGI		 PMID:24302887 GO_REF:0000107 NCBI chrNW_004936491:8,238,644...8,749,172
Ensembl chrNW_004936491:8,239,284...8,485,636 		JBrowse link
negative regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap24 Rho GTPase activating protein 24 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21911940) MGI
TreeGrafter		 PMID:21911940 GO_REF:0000118 NCBI chrNW_004936896:57,250...213,918
Ensembl chrNW_004936896:145,297...214,794 		JBrowse link
G Evl Enah/Vasp-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936604:3,720,038...3,819,928
Ensembl chrNW_004936604:3,719,976...3,822,334 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:4,125,302...4,255,880
Ensembl chrNW_004936503:4,122,204...4,246,680 		JBrowse link
G LOC101967251 profilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,992,508...1,993,271 JBrowse link
G Pfn2 profilin 2 involved_in IEA Ensembl GO_REF:0000107
G Stap1 signal transducing adaptor family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936582:877,241...908,697
Ensembl chrNW_004936582:877,474...913,770 		JBrowse link
G Tacstd2 tumor associated calcium signal transducer 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936522:3,206,826...3,208,675
Ensembl chrNW_004936522:3,206,957...3,207,919 		JBrowse link
positive regulation of ruffle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:18,036,233...18,049,144
Ensembl chrNW_004936475:18,035,994...18,049,129 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein involved_in ISO (PMID:17956734) BHF-UCL PMID:17956734 NCBI chrNW_004936686:621,502...872,824 JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 ISO RGD PMID:16260607 RGD:11557987 NCBI chrNW_004936471:38,264,455...38,331,995
Ensembl chrNW_004936471:38,267,703...38,332,218 		JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:158,115...174,524
Ensembl chrNW_004936641:157,931...174,536 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936587:1,785,721...1,951,474
Ensembl chrNW_004936587:1,785,303...1,951,332 		JBrowse link
G Eps8l1 EPS8 signaling adaptor L1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936886:380,533...388,931
Ensembl chrNW_004936886:380,533...388,901 		JBrowse link
G Eps8l2 EPS8 signaling adaptor L2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936888:506,144...523,280
Ensembl chrNW_004936888:506,138...523,302 		JBrowse link
G Eps8l3 EPS8 signaling adaptor L3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936704:1,241,341...1,251,702 JBrowse link
G Fam98a family with sequence similarity 98 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:77,729...92,427
Ensembl chrNW_004936493:77,815...90,702 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1 like 1 involved_in ISO (PMID:27777970) UniProt PMID:27777970 NCBI chrNW_004936595:1,656,956...1,692,775
Ensembl chrNW_004936595:1,656,956...1,689,322 		JBrowse link
G Nlgn1 neuroligin 1 involved_in ISO PMID:12930820 BHF-UCL PMID:12930820 RGD:8554754 NCBI chrNW_004936703:951,935...1,415,991
Ensembl chrNW_004936703:758,647...1,414,185 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in ISO PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
G Pfn1 profilin 1 involved_in ISO (PMID:23153535) UniProt PMID:23153535 NCBI chrNW_004936677:2,762,971...2,766,038
Ensembl chrNW_004936677:2,762,971...2,766,149 		JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:1,685,902...1,732,361
Ensembl chrNW_004936541:1,685,923...1,732,420 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16036
    regulation of biological process 10910
      regulation of cellular process 10579
        regulation of cellular component biogenesis 1106
          regulation of cell projection assembly 238
            regulation of plasma membrane bounded cell projection assembly 235
              regulation of ruffle assembly 31
                negative regulation of ruffle assembly 7
                positive regulation of ruffle assembly 15
Path 2
Term Annotations click to browse term
  biological_process 16036
    cellular process 15649
      cellular component organization or biogenesis 6556
        cellular component organization 6363
          cell projection organization 1786
            plasma membrane bounded cell projection organization 1761
              ruffle organization 58
                ruffle assembly 45
                  regulation of ruffle assembly 31
                    negative regulation of ruffle assembly 7
                    positive regulation of ruffle assembly 15
paths to the root