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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (PMID:26764350) MGI PMID:26764350 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055 		JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035)
(PMID:9151699)		 ARUK-UCL PMID:9151699 PMID:16493035 NCBI chr19:51,606,681...51,612,751 JBrowse link
G MVP major vault protein involved_in ISO (PMID:16441665) UniProt PMID:16441665 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G PTK6 protein tyrosine kinase 6 involved_in ISO (PMID:15539407) UniProt PMID:15539407 Ensembl chr20:61,453,386...61,462,951 JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570 		JBrowse link
G SRCIN1 SRC kinase signaling inhibitor 1 involved_in ISO (PMID:17525734) UniProt PMID:17525734 NCBI chr17:18,666,094...18,742,015
Ensembl chr17:18,942,084...19,015,744 		JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:75,415,055...75,423,279
Ensembl chr17:81,144,837...81,151,962 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO PMID:17599051
(PMID:18046415)
(PMID:16648858)		 UniProt PMID:16648858 PMID:17599051 PMID:18046415 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A involved_in ISO (PMID:25744720) UniProt PMID:25744720 NCBI chr12:12,905,682...12,928,596
Ensembl chr12:13,282,865...13,305,727 		JBrowse link
G PSEN1 presenilin 1 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
G TSG101 tumor susceptibility 101 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149 		JBrowse link
G VPS25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:14,538,322...14,544,573
Ensembl chr17:14,763,523...14,769,672 		JBrowse link
G ZFYVE28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) UniProt PMID:19460345 NCBI chr 4:2,412,659...2,564,741
Ensembl chr 4:2,320,446...2,470,638 		JBrowse link
G ZGPAT zinc finger CCCH-type and G-patch domain containing involved_in ISO (PMID:19644445) UniProt PMID:19644445 Ensembl chr20:61,630,271...61,662,967 JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of molecular function 1716
        regulation of catalytic activity 1157
          regulation of transferase activity 579
            negative regulation of transferase activity 206
              negative regulation of kinase activity 187
                negative regulation of protein kinase activity 172
                  negative regulation of protein tyrosine kinase activity 20
                    negative regulation of epidermal growth factor-activated receptor activity 12
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        regulation of cellular process 10895
          regulation of metabolic process 6441
            regulation of macromolecule metabolic process 5912
              regulation of protein metabolic process 2015
                regulation of protein modification process 1159
                  regulation of protein phosphorylation 890
                    negative regulation of protein phosphorylation 296
                      negative regulation of protein kinase activity 172
                        negative regulation of protein tyrosine kinase activity 20
                          negative regulation of epidermal growth factor-activated receptor activity 12
                          negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root