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ONTOLOGY REPORT - ANNOTATIONS


Term:microtubule severing
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Accession:GO:0051013 term browser browse the term
Definition:The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.
Synonyms:related_synonym: microtubule severing activity


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microtubule severing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIGNL2 fidgetin like 2 involved_in ISO (PMID:25756798), (PMID:36523161) UniProt PMID:25756798 PMID:36523161 NCBI chr11:48,010,951...48,021,889 JBrowse link
G KATNA1 katanin catalytic subunit A1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:20530212) RGD
TreeGrafter
MGI
InterPro
UniProt
PMID:15944385 PMID:20530212 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 RGD:2316489 NCBI chr13:21,979,755...22,040,247
Ensembl chr13:21,993,836...22,044,525
JBrowse link
G KATNAL1 katanin catalytic subunit A1 like 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22654668) InterPro
UniProt
Ensembl
MGI
TreeGrafter
PMID:22654668 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:9,106,622...9,198,403
Ensembl chr 3:9,107,161...9,198,111
JBrowse link
G KATNAL2 katanin catalytic subunit A1 like 2 involved_in IEA UniProt GO_REF:0000104 NCBI chr18:33,848,471...33,967,832
Ensembl chr18:33,848,748...33,907,092
JBrowse link
G KATNB1 katanin regulatory subunit B1 involved_in ISO
IEA
RGD
UniProt
InterPro
PMID:15944385 GO_REF:0000002 GO_REF:0000104 RGD:2316489 NCBI chr 5:43,666,892...43,688,110
Ensembl chr 5:43,666,940...43,687,807
JBrowse link
G LZTS2 leucine zipper tumor suppressor 2 involved_in IEA UniProt GO_REF:0000104 NCBI chr 9:94,015,432...94,026,191
Ensembl chr 9:94,018,257...94,027,268
JBrowse link
G SPAST spastin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20530212) UniProt
MGI
Ensembl
PMID:20530212 GO_REF:0000104 GO_REF:0000107 NCBI chr14:75,343,437...75,429,196
Ensembl chr14:75,343,327...75,429,139
JBrowse link
G TTLL11 tubulin tyrosine ligase like 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20530212) Ensembl
MGI
PMID:20530212 GO_REF:0000107 NCBI chr12:17,497,600...17,774,907
Ensembl chr12:17,498,048...17,772,485
JBrowse link
G TTLL6 tubulin tyrosine ligase like 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:20530212) MGI
Ensembl
PMID:20530212 GO_REF:0000107 NCBI chr16:69,179,314...69,232,038
Ensembl chr16:69,179,323...69,215,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17042
    cellular process 16561
      microtubule-based process 1045
        microtubule cytoskeleton organization 683
          microtubule severing 9
Path 2
Term Annotations click to browse term
  biological_process 17042
    cellular process 16561
      cellular component organization or biogenesis 6939
        cellular component organization 6720
          organelle organization 3678
            cytoskeleton organization 1519
              microtubule cytoskeleton organization 683
                microtubule severing 9
paths to the root