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ONTOLOGY REPORT - ANNOTATIONS

Term:smooth muscle cell proliferation
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Accession:GO:0048659 term browser browse the term
Definition:The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.
Synonyms:exact_synonym: SMC proliferation


show annotations for term's descendants           Sort by:
smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within IDA
ISO		 MGI:2183545 (PMID:9788961)
MGI:1857121|MGI:2183545 (PMID:10318840), (PMID:8675666)		 RGD PMID:8675666 PMID:9788961 PMID:10318840 PMID:21292788 RGD:5129183 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Calcrl calcitonin receptor like receptor acts_upstream_of ISO (PMID:16537897) RGD PMID:16537897 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISO
ISS		 (PMID:20139355)
GO_REF:0000024		 RGD
UniProt		 PMID:20139355 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:16543720 RGD:4892323 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Naa35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16484612)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16484612 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,034,360...5,086,456
Ensembl chr17:5,034,356...5,086,386 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:22082675 UniProt PMID:22082675 RGD:10047303 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IEP RGD PMID:12117720 RGD:39456082 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
negative regulation of smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 IMP RGD PMID:20703229 RGD:9685431 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:1857121|MGI:2183545 (PMID:10318840), (PMID:8675666) RGD PMID:8675666 PMID:10318840 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Aif1 allograft inflammatory factor 1 involved_in ISO (PMID:22116621), (PMID:9614071) RGD PMID:9614071 PMID:22116621 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Ang angiogenin involved_in ISO (PMID:10103013) RGD PMID:10103013 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Apod apolipoprotein D involved_in ISO
ISS		 (PMID:14551159)
GO_REF:0000024		 RGD
UniProt		 PMID:14551159 GO_REF:0000024 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of ISO UniProtKB:P21274 (PMID:18382765) RGD PMID:18382765 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 UniProtKB:P01137 (PMID:18382765), (PMID:28467929)
UniProtKB:P37238 (PMID:18382765)
GO_REF:0000107		 RGD
Ensembl		 PMID:18382765 PMID:28467929 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO UniProtKB:P12643 (PMID:18382765) RGD PMID:18382765 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Cav1 caveolin 1 IMP RGD PMID:20828553 RGD:6849298 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Comt catechol-O-methyltransferase IMP RGD PMID:11071850 RGD:2289790 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 involved_in ISO (PMID:17122440) RGD PMID:17122440 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:22099601 RGD:8553200 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:22099601 RGD:8553200 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:17600318)		 Ensembl
RGD		 PMID:17600318 PMID:19885007 GO_REF:0000107, RGD:4145298 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 involved_in ISO
IEA		 (PMID:10766744)
GO_REF:0000107		 RGD
Ensembl		 PMID:10766744 GO_REF:0000107 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 involved_in ISO (PMID:10766744) RGD PMID:10766744 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:16942485)
GO_REF:0000107		 RGD
Ensembl		 PMID:16942485 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 IMP RGD PMID:17667861 RGD:5013835 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Ilk integrin-linked kinase IMP reduction of wound healing in culture RGD PMID:18535176 RGD:2301740 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in IDA
IMP		 vascular smooth muscle cell
PMID:19531492		 RGD
UniProt		 PMID:17659301 PMID:19531492 RGD:1643591, RGD:8553301 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Mfn2 mitofusin 2 involved_in IDA PMID:15322553 UniProt PMID:15322553 RGD:1304351 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Ndrg4 NDRG family member 4 involved_in ISO
IEA		 (PMID:12755708)
GO_REF:0000107		 RGD
Ensembl		 PMID:12755708 GO_REF:0000107 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Nos3 nitric oxide synthase 3 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:1857229 (PMID:20554900)
GO_REF:0000107		 RGD
Ensembl		 PMID:20554900 PMID:12388111 PMID:14871555 GO_REF:0000107, RGD:628542, RGD:1580270 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nppb natriuretic peptide B IDA RGD PMID:19104909 RGD:2324682 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:19104909 RGD:2324682 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IMP RGD PMID:21457229 RGD:7327141 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Ogn osteoglycin involved_in IMP PMID:21519924 UniProt PMID:21519924 RGD:8554796 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IMP cAMP-dependent RGD PMID:19783773 RGD:4107736 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:18585719 RGD:2324882 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of ISO
IGI		 UniProtKB:P01137 (PMID:18382765), (PMID:20622039), (PMID:28467929), (PMID:29182484), (PMID:31023188)
UniProtKB:P21274 (PMID:18382765), (PMID:21880694)
PMID:28867608		 RGD PMID:18382765 PMID:20622039 PMID:21880694 PMID:28467929 PMID:29182484 More... RGD:150521633 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha involved_in
acts_upstream_of		 IMP
IEA
ISO		 GO_REF:0000107
(PMID:29182484)		 Ensembl
RGD		 PMID:29182484 PMID:19142226 GO_REF:0000107, RGD:10059645 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptgir prostaglandin I2 receptor involved_in ISO
IBA		 (PMID:20622039)
GO_REF:0000033		 RGD
GO_Central		 PMID:20622039 GO_REF:0000033 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979 		JBrowse link
G Ptgis prostaglandin I2 synthase IMP RGD PMID:10073980 RGD:401960092 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:16648138 RGD:1626091 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
G Sf1 splicing factor 1 IMP RGD PMID:11748220 RGD:632653 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:16816117) RGD PMID:16816117 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tp53 tumor protein p53 IMP RGD PMID:17659301 RGD:1643591 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (PMID:17452330) RGD PMID:17452330 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Vip vasoactive intestinal peptide IMP RGD PMID:20452385 RGD:5685633 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 IMP RGD PMID:20452385 RGD:5685633 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
negative regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:12070119)		 UniProt
RGD		 PMID:12070119 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2183545 (PMID:8675666) RGD PMID:8675666 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Apln apelin involved_in ISO (PMID:23263626) RGD PMID:23263626 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Cav1 caveolin 1 IMP RGD PMID:29069575 RGD:151347449 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:25681685) RGD PMID:25681685 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in ISO
IMP		 (PMID:19088079) RGD PMID:19088079 PMID:28854428 RGD:152025191 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cnn1 calponin 1 involved_in ISO UniProtKB:P17861-2 (PMID:26315405) RGD PMID:26315405 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098 		JBrowse link
G Drd4 dopamine receptor D4 IDA RGD PMID:24888351 RGD:13506962 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 involved_in ISO (PMID:23636094) RGD PMID:23636094 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
G Gna12 G protein subunit alpha 12 acts_upstream_of_or_within IMP PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Gna13 G protein subunit alpha 13 acts_upstream_of_or_within IMP PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA		 (PMID:23840305)
GO_REF:0000107		 RGD
Ensembl		 PMID:23840305 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 IMP RGD PMID:24321768 RGD:10401938 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hmox1 heme oxygenase 1 IMP RGD PMID:22709785 RGD:10755720 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il10 interleukin 10 involved_in ISO UniProtKB:P06804 (PMID:26808574) RGD PMID:26808574 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO
IEA		 RNAcentral:URS000001C659_9606|RNAcentral:URS000075BB59_9606 (PMID:26184978), (PMID:28799067)
GO_REF:0000107		 RGD
Ensembl		 PMID:26184978 PMID:28799067 GO_REF:0000107 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28478070 RGD:12910733 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir1 microRNA 1 involved_in ISO (PMID:21051663), (PMID:26166810) RGD PMID:21051663 PMID:26166810 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:29700287 RGD:26884455 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir137 microRNA 137 involved_in ISO (PMID:29016699) RGD PMID:29016699 NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985 		JBrowse link
G Mir140 microRNA 140 involved_in ISO (PMID:27021683), (PMID:27214554) RGD PMID:27021683 PMID:27214554 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir1b microRNA 1b involved_in ISO (PMID:21051663), (PMID:26166810) RGD PMID:21051663 PMID:26166810 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Mir214 microRNA 214 involved_in ISO (PMID:27927633) RGD PMID:27927633 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir223 microRNA 223 involved_in IDA
ISO		 (PMID:27121304) RGD PMID:27121304 PMID:30246291 RGD:25823198 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir322 microRNA 322 involved_in ISO RNAcentral:URS00000F6E49_9606 (PMID:23263626) RGD PMID:23263626 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir34a microRNA 34a involved_in ISO (PMID:24792364), (PMID:26493107), (PMID:27302634) RGD PMID:24792364 PMID:26493107 PMID:27302634 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180 		JBrowse link
G Mir503 microRNA 503 involved_in ISO RNAcentral:URS00000F0F49_9606 (PMID:21220732), (PMID:23263626) RGD PMID:21220732 PMID:23263626 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir665 microRNA 665 involved_in ISO (PMID:29118903) RGD PMID:29118903 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir96 microRNA 96 involved_in ISO (PMID:25871906) RGD PMID:25871906 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Myocd myocardin involved_in IEA
ISO		 GO_REF:0000107
(PMID:23825366)		 Ensembl
RGD		 PMID:23825366 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Ndrg2 NDRG family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16520977)		 Ensembl
RGD		 PMID:16520977 GO_REF:0000107 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Park7 Parkinsonism associated deglycase IDA RGD PMID:29069575 RGD:151347449 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:24960162), (PMID:28522568) RGD PMID:24960162 PMID:28522568 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:25447536) RGD PMID:25447536 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:26208095) RGD PMID:26208095 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rbm10 RNA binding motif protein 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:87964 (PMID:19508861)		 Ensembl
RGD		 PMID:19508861 GO_REF:0000107 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 IDA RGD PMID:18207159 RGD:13524535 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518 		JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within IMP PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 acts_upstream_of_or_within IGI PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:27021683) RGD PMID:27021683 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tafa5 TAFA chemokine like family member 5 acts_upstream_of_or_within ISO
IDA
IGI		 (PMID:29453251) RGD PMID:29453251 PMID:29453251 PMID:29453251 RGD:42721986, RGD:42721986 NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:118,613,889...118,834,353 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 IMP RGD PMID:28854428 RGD:152025191 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO
IEA		 (PMID:21817107)
GO_REF:0000107		 RGD
Ensembl		 PMID:21817107 GO_REF:0000107 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
positive regulation of smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 IMP RGD PMID:18636120 RGD:2301071 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:16368901 PMID:23212096 RGD:1625344, RGD:7244285 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aif1 allograft inflammatory factor 1 involved_in IMP
ISS
ISO		 GO_REF:0000024
(PMID:15117732), (PMID:22116621)		 UniProt
RGD		 PMID:15117732 PMID:22116621 PMID:18779232 GO_REF:0000024, RGD:2313013 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 IMP RGD PMID:16648138 RGD:1626091 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:21321938)
GO_REF:0000107		 RGD
Ensembl		 PMID:21321938 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:16199435 RGD:5509792 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17600318)		 Ensembl
RGD		 PMID:17600318 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G C3ar1 complement C3a receptor 1 IMP RGD PMID:22089112 RGD:7411627 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:21297082) RGD PMID:21297082 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:23807044 RGD:10003107 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Cdh13 cadherin 13 involved_in ISO (PMID:15364621) RGD PMID:15364621 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IDA PMID:12729461 RGD
ARUK-UCL		 PMID:17182651 PMID:12729461 RGD:4891893, RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cyba cytochrome b-245 alpha chain IMP RGD PMID:15036821 RGD:8693734 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:10393673) RGD PMID:10393673 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:15486316 RGD:1581908 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 IMP RGD PMID:23973488 RGD:10395311 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elane elastase, neutrophil expressed involved_in ISO (PMID:15010259) RGD PMID:15010259 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Ereg epiregulin involved_in IMP
IDA		 PMID:9990076 RGD
UniProt		 PMID:14570897 PMID:9990076 RGD:2316285, RGD:632743 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:9854551 RGD:8655666 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IDA RGD PMID:12062723 RGD:1582498 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:24023716) RGD PMID:24023716 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:21557011 RGD:10045551 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in ISO (PMID:1840698) RGD PMID:1840698 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hdac1 histone deacetylase 1 involved_in IGI PMID:28867608 BHF-UCL PMID:28867608 RGD:150521633 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO
ISS		 UniProtKB:Q61982 (PMID:19855400)
GO_REF:0000024		 RGD
UniProt		 PMID:19855400 GO_REF:0000024 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:16489407 RGD:1626319 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:18413661 RGD:5508694 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA		 (PMID:17600318)
GO_REF:0000107		 RGD
Ensembl		 PMID:17600318 GO_REF:0000107 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18474814)		 UniProt
RGD		 PMID:18474814 GO_REF:0000024 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:10766744), (PMID:16942485) RGD PMID:10766744 PMID:16942485 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:21854769 RGD:10046007 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20045483 RGD:4145470 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:21321938)		 Ensembl
RGD		 PMID:21321938 PMID:22636674 GO_REF:0000107, RGD:8655954 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:10510402) RGD PMID:10510402 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO
IEA		 (PMID:10510402)
GO_REF:0000107		 RGD
Ensembl		 PMID:10510402 GO_REF:0000107 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IMP RGD PMID:15890643 RGD:1579817 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Itga2 integrin subunit alpha 2 IMP RGD PMID:19239475 RGD:2307394 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:19723557 RGD:4892625 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA pulmonary artery smooth muscle cells RGD PMID:11571252 RGD:2290591 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:24312257 RGD:401700379 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Mmp2 matrix metallopeptidase 2 acts_upstream_of_or_within ISO (PMID:17561096) RGD PMID:17561096 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase IMP RGD PMID:10026172 RGD:2308868 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:19589861 RGD:10003166 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myb MYB proto-oncogene, transcription factor IMP RGD PMID:8665409 RGD:11532682 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:8113414 RGD:10059612 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IMP RGD PMID:15890643 RGD:1579817 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IMP RGD PMID:18952695 RGD:2311234 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Notch3 notch receptor 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19855400)		 Ensembl
RGD		 PMID:19855400 GO_REF:0000107 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nox1 NADPH oxidase 1 involved_in IMP PMID:10485709 BHF-UCL PMID:10485709 RGD:633401 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:12710532 RGD:1625500 NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16945922)		 UniProt
RGD		 PMID:16945922 GO_REF:0000024 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Orc1 origin recognition complex, subunit 1 IMP RGD PMID:18499104 RGD:9588277 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Pde4d phosphodiesterase 4D IMP RGD PMID:21776361 RGD:7327157 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IMP
ISO
ISS		 (PMID:10375497), (PMID:28867608)
GO_REF:0000024
(PMID:21321938)		 RGD
ARUK-UCL		 PMID:10375497 PMID:21321938 PMID:28867608 PMID:17449016 GO_REF:0000024, RGD:2292197 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfd platelet derived growth factor D IDA RGD PMID:15752751 RGD:9854640 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO
IEA
ISS		 (PMID:21679854)
(PMID:10375497)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:10375497 PMID:21679854 GO_REF:0000024 GO_REF:0000107 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Phb1 prohibitin 1 involved_in IMP PMID:32173312 UniProt PMID:32173312 RGD:30309944 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IMP RGD PMID:25908763 RGD:13207417 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21321938)		 Ensembl
RGD		 PMID:21321938 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Prkca protein kinase C, alpha IMP RGD PMID:17908462 RGD:2292473 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:8216700 RGD:10043166 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:17645304 RGD:1642591 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IMP RGD PMID:15208331 RGD:2292605 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family IMP vascular smooth muscle cells RGD PMID:21125971 RGD:4892313 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IMP RGD PMID:15247148 RGD:2306423 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Retn resistin IMP RGD PMID:20795947 RGD:7207234 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IMP RGD PMID:16148030 RGD:1643021 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:11557736 RGD:1581747 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:18436805) RGD PMID:18436805 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Shc1 SHC adaptor protein 1 IMP RGD PMID:12837289 RGD:1304398 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Skp2 S-phase kinase associated protein 2 IMP RGD PMID:19878790 RGD:2315048 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17561096)		 Ensembl
RGD		 PMID:17561096 GO_REF:0000107 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IMP RGD PMID:17293493 RGD:1600088 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IMP RGD PMID:16527988 RGD:1601384 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Sulf1 sulfatase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IMP RGD PMID:11178962 RGD:1601605 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgm2 transglutaminase 2 IDA RGD PMID:14970202 RGD:1579990 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:24615654) RGD PMID:24615654 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21880694)		 Ensembl
RGD		 PMID:21880694 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:16518841) RGD PMID:16518841 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf6 TNF receptor associated factor 6 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Vegfa vascular endothelial growth factor A IMP RGD PMID:14693680 RGD:1580560 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Zfp143 zinc finger protein 143 IMP RGD PMID:21352097 RGD:9743924 NCBI chr 1:164,109,041...164,144,902
Ensembl chr 1:164,109,116...164,144,902 		JBrowse link
positive regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 involved_in ISO
IEA		 RNAcentral:URS00003A19A3_9606 (PMID:28890348)
GO_REF:0000107		 RGD
Ensembl		 PMID:28890348 GO_REF:0000107 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Agt angiotensinogen IDA RGD PMID:24595849 RGD:11039416 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a acts_upstream_of_or_within ISO MGI:1857147 (PMID:19508861) RGD PMID:19508861 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18667463) RGD PMID:18667463 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Calcrl calcitonin receptor like receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16537897)		 Ensembl
RGD		 PMID:16537897 GO_REF:0000107 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:17267544 RGD:2303063 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:16087782 RGD:150429767 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:23246467 RGD:10401139 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA		 (PMID:27021683)
GO_REF:0000107		 RGD
Ensembl		 PMID:27021683 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Edn1 endothelin 1 involved_in IDA PMID:28484848 BHF-UCL PMID:28484848 RGD:13601996 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO UniProtKB:Q9ULZ1 (PMID:23263626) RGD PMID:23263626 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf9 fibroblast growth factor 9 involved_in ISO
IEA
IMP		 RNAcentral:URS0000355E82_9606 (PMID:29118903)
GO_REF:0000107
PMID:28259995		 RGD
Ensembl		 PMID:29118903 PMID:28259995 GO_REF:0000107, RGD:13601993 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IMP RGD PMID:15292181 RGD:2289848 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Foxj2 forkhead box J2 involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 4:156,047,043...156,073,540
Ensembl chr 4:156,046,969...156,073,518 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in IMP PMID:28947594 BHF-UCL PMID:28947594 RGD:13524616 NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of ISO (PMID:28342807) RGD PMID:28342807 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:27773680 PMID:24018045 RGD:13513992, RGD:13792711 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase IMP RGD PMID:24657469 RGD:11667099 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (PMID:25871906) RGD PMID:25871906 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:26166810)
GO_REF:0000107		 RGD
Ensembl		 PMID:26166810 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 involved_in ISO RNAcentral:URS00001E3523_9606 (PMID:29016699) RGD PMID:29016699 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:23516544 RGD:10403075 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:28701355) RGD PMID:28701355 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO
IEA		 (PMID:28257760)
GO_REF:0000107		 RGD
Ensembl		 PMID:28257760 GO_REF:0000107 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IMP RGD PMID:14638553 RGD:10412321 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IMP RGD PMID:35078016 RGD:155804282 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mdm2 MDM2 proto-oncogene IMP RGD PMID:21498419 RGD:10412065 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mef2d myocyte enhancer factor 2D involved_in ISO
IEA		 RNAcentral:URS0000355E82_9606 (PMID:29118903)
GO_REF:0000107		 RGD
Ensembl		 PMID:29118903 GO_REF:0000107 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Mfn2 mitofusin 2 involved_in ISO
IEA		 (PMID:27640178)
GO_REF:0000107		 RGD
Ensembl		 PMID:27640178 GO_REF:0000107 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir125a microRNA 125a IMP RGD PMID:30156956 RGD:26884369 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir130a microRNA 130a involved_in ISO (PMID:24960162), (PMID:25681685) RGD PMID:24960162 PMID:25681685 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir135b microRNA 135b involved_in ISO (PMID:26184978) RGD PMID:26184978 NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953 		JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:30779466) RGD PMID:30779466 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:22161164), (PMID:27640178) RGD PMID:22161164 PMID:27640178 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22450430), (PMID:25447536) RGD PMID:22450430 PMID:25447536 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:20693317), (PMID:21817107), (PMID:22034194), (PMID:26208095), (PMID:28522568) RGD PMID:20693317 PMID:21817107 PMID:22034194 PMID:26208095 PMID:28522568 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir214 microRNA 214 involved_in ISO (PMID:27144530), (PMID:28684904) RGD PMID:27144530 PMID:28684904 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19088079) RGD PMID:19088079 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 IMP RGD PMID:28854428 RGD:152025191 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:20857419) RGD PMID:20857419 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir301a microRNA 301a involved_in ISO (PMID:25681685) RGD PMID:25681685 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435 		JBrowse link
G Mir448 microRNA 448 involved_in ISO (PMID:28799067) RGD PMID:28799067 NCBI chr  X:110,829,918...110,830,029
Ensembl chr  X:110,829,918...110,830,029 		JBrowse link
G Mir499a microRNA 499a involved_in ISO (PMID:26184978) RGD PMID:26184978 NCBI chr 3:144,110,469...144,110,533
Ensembl chr 3:144,110,469...144,110,533 		JBrowse link
G Mmp2 matrix metallopeptidase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18667463)		 Ensembl
RGD		 PMID:18667463 GO_REF:0000107 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18667463)		 Ensembl
RGD		 PMID:18667463 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97528 (PMID:16644864)		 Ensembl
RGD		 PMID:16644864 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:34843718 PMID:23706097 RGD:329955360, RGD:329955579 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 IMP RGD PMID:22508052 RGD:11073699 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISO RNAcentral:URS000075DB2F_9606 (PMID:23554459) RGD PMID:23554459 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:19901155 RGD:11533949 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97306 (PMID:16644864)
(PMID:12070119), (PMID:19088079), (PMID:23554459)		 Ensembl
RGD		 PMID:12070119 PMID:16644864 PMID:19088079 PMID:23554459 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP in response to hypoxia RGD PMID:22527940 RGD:7242177 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:9227431 RGD:150521729 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tert telomerase reverse transcriptase IMP RGD PMID:24376652 RGD:11038675 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:26808574) RGD PMID:26808574 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in
NOT|involved_in		 ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
regulation of smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (PMID:15800000) RGD PMID:15800000 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS		 (PMID:17122440)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17122440 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:26439051 RGD:401794572 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Nppc natriuretic peptide C IEP RGD PMID:11742834 RGD:70639 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISO
ISS		 (PMID:25852083)
GO_REF:0000024		 RGD
UniProt		 PMID:25852083 GO_REF:0000024 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Pde1a phosphodiesterase 1A IMP RGD PMID:16514069 RGD:2312521 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:25852083) RGD PMID:25852083 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:21777465 RGD:5147661 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:17122440) RGD PMID:17122440 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:25852083) RGD PMID:25852083 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:25852083) RGD PMID:25852083 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857556 (PMID:15849236)		 Ensembl
RGD		 PMID:15849236 GO_REF:0000107 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of ISO MGI:2183545 (PMID:8675666) RGD PMID:8675666 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a acts_upstream_of ISO MGI:1857147 (PMID:19508861) RGD PMID:19508861 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Calcrl calcitonin receptor like receptor involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:16537897)		 Ensembl
RGD		 PMID:16537897 GO_REF:0000107 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISO MGI:2654034 (PMID:24530784) RGD PMID:24530784 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:2385534 (PMID:24530784) RGD PMID:24530784 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IEP RGD PMID:21463632 RGD:401794561 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Mir504 microRNA 504 acts_upstream_of_or_within_positive_effect ISO (PMID:26941017) RGD PMID:26941017 NCBI chr  X:137,318,540...137,318,616
Ensembl chr  X:137,318,540...137,318,616 		JBrowse link
G Ndrg2 NDRG family member 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:16520977)		 Ensembl
RGD		 PMID:16520977 GO_REF:0000107 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:97528 (PMID:16644864)		 Ensembl
RGD		 PMID:16644864 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 IEP RGD PMID:11181735 RGD:11556237 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
G Pdgfb platelet derived growth factor subunit B acts_upstream_of ISO MGI:97306 (PMID:16644864) RGD PMID:16644864 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 IMP RGD PMID:30237457 RGD:124713557 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605 		JBrowse link
G Rbm10 RNA binding motif protein 10 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:87964 (PMID:19508861)		 Ensembl
RGD		 PMID:19508861 GO_REF:0000107 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Spon2 spondin 2 IMP RGD PMID:25751394 RGD:329328927 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      cell population proliferation 2267
        muscle cell proliferation 315
          smooth muscle cell proliferation 233
            negative regulation of smooth muscle cell proliferation + 85
            positive regulation of smooth muscle cell proliferation + 137
            regulation of smooth muscle cell proliferation + 222
            vascular associated smooth muscle cell proliferation + 112
paths to the root