Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of Notch signaling pathway
go back to main search page
Accession:GO:0045747 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
Synonyms:exact_synonym: positive regulation of N signaling pathway;   positive regulation of N signalling pathway;   positive regulation of Notch signalling pathway;   up regulation of Notch signaling pathway;   upregulation of Notch signaling pathway
 narrow_synonym: activation of Notch signaling pathway;   stimulation of Notch signaling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi


show annotations for term's descendants           Sort by:
positive regulation of Notch signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aak1 AP2 associated kinase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21464124)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21464124 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:119,300,128...119,451,834
Ensembl chr 4:119,295,257...119,450,969 		JBrowse link
G Acvrl1 activin A receptor like type 1 acts_upstream_of ISO UniProtKB:Q9UK05 (PMID:32561494) RGD PMID:32561494 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857470 (PMID:11073877) RGD PMID:11073877 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Bmp2k BMP-2 inducible kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12050162), (PMID:20139355)		 UniProt
RGD		 PMID:12050162 PMID:20139355 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Cntn6 contactin 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:25074942)		 Ensembl
RGD		 PMID:25074942 GO_REF:0000107 NCBI chr 4:137,354,886...137,751,712
Ensembl chr 4:137,355,367...137,751,119 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in
acts_upstream_of_or_within		 ISS
IEA
IDA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:22658936
(PMID:15574878)
(PMID:10958687), (PMID:18676613), (PMID:19144989), (PMID:19389377), (PMID:21915337), (PMID:26114479)		 UniProt
Ensembl
RGD		 PMID:10958687 PMID:15574878 PMID:18676613 PMID:19144989 PMID:19389377 More... GO_REF:0000024 GO_REF:0000107, RGD:10402035 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26114479)		 Ensembl
RGD		 PMID:26114479 GO_REF:0000107 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Enho energy homeostasis associated involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25074942)		 GO_Central
RGD		 PMID:25074942 GO_REF:0000033 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777 		JBrowse link
G Epn2 epsin 2 involved_in ISO
IEA		 (PMID:28717225)
GO_REF:0000107		 RGD
Ensembl		 PMID:28717225 GO_REF:0000107 NCBI chr10:46,197,785...46,259,673
Ensembl chr10:46,197,785...46,259,642 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:103302 (PMID:16324690) RGD PMID:16324690 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (PMID:21633169) RGD PMID:21633169 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Gdf2 growth differentiation factor 2 acts_upstream_of ISO (PMID:32561494) RGD PMID:32561494 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Gsx2 GS homeobox 2 acts_upstream_of_or_within ISO (PMID:23042297) RGD PMID:23042297 NCBI chr14:33,123,799...33,126,151
Ensembl chr14:33,124,381...33,126,105 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12208538)		 Ensembl
RGD		 PMID:12208538 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO (PMID:12208538) RGD PMID:12208538 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO
IEA		 (PMID:25731159)
GO_REF:0000107		 RGD
Ensembl		 PMID:25731159 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:10958687)		 UniProt
Ensembl
RGD		 PMID:10958687 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:10958687)		 UniProt
Ensembl
RGD		 PMID:10958687 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:15302600 RGD:2292509 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15574878)		 Ensembl
RGD		 PMID:15574878 GO_REF:0000107 NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (PMID:18593560) RGD PMID:18593560 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISO (PMID:15574878) RGD PMID:15574878 NCBI chr 7:110,310,810...110,328,653
Ensembl chr 7:110,310,812...110,328,653 		JBrowse link
G Mir212 microRNA 212 involved_in ISO (PMID:25217442) RGD PMID:25217442 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Nepro nucleolus and neural progenitor protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:19906856)		 GO_Central
RGD		 PMID:19906856 GO_REF:0000033 NCBI chr11:55,958,265...55,970,432
Ensembl chr11:55,958,267...55,970,432 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:21156799) RGD PMID:21156799 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (PMID:24667410) RGD PMID:24667410 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA		 (PMID:23388056)
GO_REF:0000107		 RGD
Ensembl		 PMID:23388056 GO_REF:0000107 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Poglut1 protein O-glucosyltransferase 1 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:27807076)
GO_REF:0000033
(PMID:26496195)		 UniProt
Ensembl
RGD
GO_Central		 PMID:26496195 PMID:27807076 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:62,198,600...62,226,446
Ensembl chr11:62,198,513...62,226,434 		JBrowse link
G Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15574878)		 Ensembl
RGD		 PMID:15574878 GO_REF:0000107 NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:25691540) RGD PMID:25691540 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (PMID:25691540) RGD PMID:25691540 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Slc35c2 solute carrier family 35 member C2 acts_upstream_of_or_within ISO (PMID:20837470) RGD PMID:20837470 NCBI chr 3:154,012,262...154,023,549
Ensembl chr 3:154,012,416...154,023,488 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:16631155) RGD PMID:16631155 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:25731159) RGD PMID:25731159 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15156153)		 UniProt
Ensembl
RGD		 PMID:15156153 GO_REF:0000024 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
IEA		 (PMID:25217442)
GO_REF:0000107		 RGD
Ensembl		 PMID:25217442 GO_REF:0000107 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tp63 tumor protein p63 involved_in
acts_upstream_of_or_within		 ISO (PMID:11641404)
MGI:5140823 (PMID:22274697)		 RGD PMID:11641404 PMID:22274697 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tspan14 tetraspanin 14 involved_in ISO (PMID:23091066) RGD PMID:23091066 NCBI chr16:16,784,242...16,841,368
Ensembl chr16:16,783,234...16,841,400 		JBrowse link
G Tspan5 tetraspanin 5 involved_in ISO (PMID:23091066) RGD PMID:23091066 NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in IEA
ISO		 GO_REF:0000107
(PMID:25731159)		 Ensembl
RGD		 PMID:25731159 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:26522984) RGD PMID:26522984 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    response to stimulus 10793
      positive regulation of response to stimulus 2530
        positive regulation of signal transduction 1748
          positive regulation of Notch signaling pathway 44
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of biological process 13131
        signaling 7741
          signal transduction 7181
            cell surface receptor signaling pathway 2842
              Notch signaling pathway 194
                regulation of Notch signaling pathway 96
                  positive regulation of Notch signaling pathway 44
paths to the root