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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic G2/M transition checkpoint
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Accession:GO:0044818 term browser browse the term
Definition:A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.


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mitotic G2/M transition checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase involved_in ISO (PMID:30139873) UniProt PMID:30139873 NCBI chrNW_004955508:3,337,036...3,440,313
Ensembl chrNW_004955508:3,337,432...3,440,257
JBrowse link
G Brca1 BRCA1 DNA repair associated acts_upstream_of_or_within ISO (PMID:15254237) MGI PMID:15254237 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:19223857) UniProt PMID:19223857 NCBI chrNW_004955451:13,160,811...13,170,012
Ensembl chrNW_004955451:13,120,761...13,170,073
JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:33108758)
(PMID:9278511)
UniProt PMID:9278511 PMID:33108758 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:18172500), (PMID:19182791) UniProt PMID:18172500 PMID:19182791 NCBI chrNW_004955482:233,485...267,064
Ensembl chrNW_004955482:233,486...267,064
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:30139873) UniProt PMID:30139873 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007
JBrowse link
G Inip INTS3 and NABP interacting protein involved_in ISO (PMID:19683501) ComplexPortal PMID:19683501 NCBI chrNW_004955419:14,729,275...14,732,971
Ensembl chrNW_004955419:14,728,816...14,732,971
JBrowse link
G Ints3 integrator complex subunit 3 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955545:352,170...394,751
Ensembl chrNW_004955545:351,872...396,052
JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955403:7,603,002...7,610,925
Ensembl chrNW_004955403:7,604,144...7,611,042
JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955458:3,835,205...3,836,841
Ensembl chrNW_004955458:3,835,205...3,840,634
JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO (PMID:33108758) UniProt PMID:33108758 NCBI chrNW_004955434:4,250,105...4,251,508 JBrowse link
mitotic DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clspn claspin involved_in ISO (PMID:16885022) UniProt PMID:16885022 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039
JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 involved_in ISO (PMID:10722740) UniProt PMID:10722740 NCBI chrNW_004955433:23,333,797...23,358,255
Ensembl chrNW_004955433:23,333,742...23,358,579
JBrowse link
G Znf830 zinc finger protein 830 involved_in ISO (PMID:21191184) UniProt PMID:21191184 NCBI chrNW_004955481:9,661,791...9,663,326
Ensembl chrNW_004955481:9,661,830...9,662,918
JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004955474:6,252,321...6,265,518
Ensembl chrNW_004955474:6,252,321...6,265,286
JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:15149599) BHF-UCL PMID:15149599 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISO (PMID:19261746), (PMID:19261748), (PMID:19261749) UniProt PMID:19261746 PMID:19261748 PMID:19261749 NCBI chrNW_004955524:939,250...944,457
Ensembl chrNW_004955524:937,815...944,456
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO (PMID:19261748) UniProt PMID:19261748 NCBI chrNW_004955469:9,831,488...10,246,631
Ensembl chrNW_004955469:9,831,488...10,246,899
JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) UniProt PMID:11309417 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687
JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProt PMID:17525341 PMID:19261746 PMID:19261748 NCBI chrNW_004955594:551,407...613,772
Ensembl chrNW_004955594:554,081...613,661
JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO (PMID:15150265) UniProt PMID:15150265 NCBI chrNW_004955567:924,728...943,092
Ensembl chrNW_004955567:924,734...943,701
JBrowse link
G Ccng1 cyclin G1 ISO RGD PMID:9464250 RGD:2316029 NCBI chrNW_004955408:16,846,050...16,850,365 JBrowse link
G Cdc14b cell division cycle 14B involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955422:23,303,472...23,445,785
Ensembl chrNW_004955422:23,303,250...23,322,493
JBrowse link
G Cdk1 cyclin dependent kinase 1 acts_upstream_of_or_within ISO (PMID:12937170) MGI PMID:12937170 NCBI chrNW_004955425:14,210,681...14,226,474
Ensembl chrNW_004955425:14,210,680...14,226,474
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:15790566) UniProt PMID:15790566 NCBI chrNW_004955451:13,160,811...13,170,012
Ensembl chrNW_004955451:13,120,761...13,170,073
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) UniProt PMID:23213251 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479
JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:20932473) UniProt PMID:20932473 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Clspn claspin involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955422:1,702,131...1,734,603
Ensembl chrNW_004955422:1,700,692...1,734,773
JBrowse link
G CUNH10orf90 chromosome unknown C10orf90 homolog involved_in ISO (PMID:20154723) UniProt PMID:20154723 NCBI chrNW_004955477:4,299,277...4,510,702
Ensembl chrNW_004955477:4,297,588...4,510,959
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO (PMID:17085480) UniProt PMID:17085480 NCBI chrNW_004955406:5,256,057...5,299,573
Ensembl chrNW_004955406:5,254,558...5,299,573
JBrowse link
G Foxn3 forkhead box N3 involved_in ISO (PMID:9154802) UniProt PMID:9154802 NCBI chrNW_004955438:11,720,563...12,126,185
Ensembl chrNW_004955438:11,720,570...12,126,185
JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within ISO (PMID:12048180) MGI PMID:12048180 NCBI chrNW_004955475:10,666,024...10,673,717
Ensembl chrNW_004955475:10,665,987...10,674,110
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955495:5,481,914...5,503,690
Ensembl chrNW_004955495:5,481,916...5,505,521
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:20467439) MGI PMID:20467439 NCBI chrNW_004955583:730,353...731,301
Ensembl chrNW_004955583:730,289...731,260
JBrowse link
G Mbd4 methyl-CpG binding domain 4, DNA glycosylase acts_upstream_of_or_within ISO (PMID:14614141) MGI PMID:14614141 NCBI chrNW_004955429:17,858,656...17,868,111
Ensembl chrNW_004955429:17,858,937...17,869,262
JBrowse link
G Mbtps1 membrane bound transcription factor peptidase, site 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955564:176,230...226,555
Ensembl chrNW_004955564:176,230...228,587
JBrowse link
G Mbtps2 membrane bound transcription factor peptidase, site 2 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955509:2,185,054...2,222,497
Ensembl chrNW_004955509:2,184,522...2,222,505
JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chrNW_004955408:726,124...758,851 JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within
ISO (PMID:11438675)
(PMID:18614044)
UniProt
MGI
PMID:11438675 PMID:18614044 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) UniProt PMID:21741933 NCBI chrNW_004955574:1,505,997...1,514,680
Ensembl chrNW_004955574:1,506,022...1,517,130
JBrowse link
G Plk1 polo like kinase 1 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955493:2,206,353...2,217,231
Ensembl chrNW_004955493:2,206,353...2,217,231
JBrowse link
G Rint1 RAD50 interactor 1 involved_in ISO (PMID:11096100) BHF-UCL PMID:11096100 NCBI chrNW_004955410:10,121,322...10,144,748
Ensembl chrNW_004955410:10,121,219...10,144,748
JBrowse link
G Syf2 SYF2 pre-mRNA splicing factor acts_upstream_of_or_within ISO (PMID:22448250) MGI PMID:22448250 NCBI chrNW_004955452:4,850,049...4,856,647
Ensembl chrNW_004955452:4,848,659...4,857,114
JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955481:3,698,686...3,836,209
Ensembl chrNW_004955481:3,705,202...3,772,116
JBrowse link
G Taok2 TAO kinase 2 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955493:6,968,537...6,986,608
Ensembl chrNW_004955493:6,969,096...6,985,878
JBrowse link
G Taok3 TAO kinase 3 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955455:13,020,618...13,207,539
Ensembl chrNW_004955455:13,103,357...13,211,315
JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 NCBI chrNW_004955408:29,154,373...29,274,817
Ensembl chrNW_004955408:29,154,629...29,274,856
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      cell cycle process 1065
        mitotic cell cycle process 604
          mitotic cell cycle checkpoint signaling 118
            mitotic G2/M transition checkpoint 46
              mitotic DNA replication checkpoint signaling 4
              mitotic G2 DNA damage checkpoint signaling 36
Path 2
Term Annotations click to browse term
  biological_process 12572
    biological regulation 9067
      regulation of biological process 8766
        regulation of cellular process 8474
          regulation of cell cycle 912
            regulation of cell cycle process 637
              negative regulation of cell cycle process 256
                negative regulation of cell cycle phase transition 210
                  cell cycle checkpoint signaling 156
                    mitotic cell cycle checkpoint signaling 118
                      mitotic G2/M transition checkpoint 46
                        mitotic DNA replication checkpoint signaling 4
                        mitotic G2 DNA damage checkpoint signaling 36
paths to the root