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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of appetite by leptin-mediated signaling pathway
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Accession:GO:0038108 term browser browse the term
Definition:The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.
Synonyms:exact_synonym: inhibition of appetite by leptin signaling;   negative regulation of appetite by leptin-mediated signalling pathway;   reduction of appetite by leptin-mediated signaling;   suppression of appetite by leptin-mediated signaling pathway


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negative regulation of appetite by leptin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbs2 Bardet-Biedl syndrome 2 involved_in ISO (PMID:19150989) RGD PMID:19150989 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 involved_in ISO (PMID:19150989) RGD PMID:19150989 NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607 		JBrowse link
G Lep leptin involved_in IDA
IBA		 PMID:11677594
GO_REF:0000033		 GO_Central PMID:11677594 GO_REF:0000033, RGD:10448951 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mkks MKKS centrosomal shuttling protein involved_in ISO (PMID:19150989) RGD PMID:19150989 NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    response to stimulus 10793
      response to nutrient levels 841
        regulation of appetite 30
          negative regulation of appetite 16
            negative regulation of appetite by leptin-mediated signaling pathway 4
Path 2
Term Annotations click to browse term
  biological_process 20075
    biological regulation 13559
      regulation of biological process 13136
        regulation of response to stimulus 4297
          regulation of response to nutrient levels 42
            regulation of response to food 25
              negative regulation of response to food 17
                negative regulation of appetite 16
                  negative regulation of appetite by leptin-mediated signaling pathway 4
paths to the root