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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of toll-like receptor signaling pathway
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Accession:GO:0034121 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms:exact_synonym: regulation of TLR signaling pathway;   regulation of toll-like receptor signalling pathway

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regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO (PMID:22659029) MGI PMID:22659029 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:20547752) UniProt PMID:20547752 NCBI chrNW_004955423:2,024,084...2,032,530
Ensembl chrNW_004955423:2,022,417...2,033,149 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:20616063) UniProt PMID:20616063 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,596,406...1,610,479
Ensembl chrNW_004955553:1,488,501...1,610,555 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (PMID:16378096) UniProt PMID:16378096 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004955495:5,561,359...5,571,945
Ensembl chrNW_004955495:5,561,979...5,571,682 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISO (PMID:30332431) UniProt PMID:30332431 NCBI chrNW_004955495:2,782,549...2,789,470
Ensembl chrNW_004955495:2,782,606...2,789,815 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) UniProt PMID:28039360 NCBI chrNW_004955467:9,600,829...9,604,148
Ensembl chrNW_004955467:9,600,829...9,603,606 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:12150927) BHF-UCL PMID:12150927 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chrNW_004955465:12,497,534...12,512,529
Ensembl chrNW_004955465:12,497,462...12,513,106 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (PMID:23589304) UniProt PMID:23589304 NCBI chrNW_004955476:6,611,102...6,629,294
Ensembl chrNW_004955476:6,610,103...6,629,264 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO (PMID:27426725) UniProt PMID:27426725 NCBI chrNW_004955454:3,142,621...3,146,470
Ensembl chrNW_004955454:3,142,636...3,146,470 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004955437:90,623...100,918
Ensembl chrNW_004955437:90,577...100,918 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:22763455) MGI PMID:22763455 NCBI chrNW_004955476:11,755,489...11,762,781 JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO (PMID:29395066) UniProt PMID:29395066 NCBI chrNW_004955428:1,062,998...1,108,711
Ensembl chrNW_004955428:1,062,998...1,115,415 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:20584979) UniProt PMID:20584979 NCBI chrNW_004955442:14,685,089...14,772,870
Ensembl chrNW_004955442:14,685,153...14,772,870 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955568:263,302...349,192
Ensembl chrNW_004955568:263,302...349,192 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B involved_in ISO (PMID:26095358) UniProt PMID:26095358 NCBI chrNW_004955452:7,114,746...7,138,924
Ensembl chrNW_004955452:7,115,204...7,139,370 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISO (PMID:18083102) UniProt PMID:18083102 NCBI chrNW_004955416:8,361,722...8,377,629
Ensembl chrNW_004955416:8,359,207...8,377,692 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955481:1,752,778...1,805,700
Ensembl chrNW_004955481:1,752,778...1,808,583 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955580:935,021...941,081
Ensembl chrNW_004955580:934,798...941,081 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (PMID:16449650) UniProt PMID:16449650 NCBI chrNW_004955573:315,764...327,833
Ensembl chrNW_004955573:315,766...331,477 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISO (PMID:17018642) UniProt PMID:17018642 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:15800576) UniProt PMID:15800576 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:15800576) UniProt PMID:15800576 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      signal transduction 4021
        regulation of signal transduction 2715
          regulation of pattern recognition receptor signaling pathway 164
            regulation of toll-like receptor signaling pathway 28
              negative regulation of toll-like receptor signaling pathway + 19
              positive regulation of toll-like receptor signaling pathway + 3
              regulation of MyD88-dependent toll-like receptor signaling pathway + 4
              regulation of MyD88-independent toll-like receptor signaling pathway + 1
              regulation of toll-like receptor 21 signaling pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 12572
    response to stimulus 6771
      response to external stimulus 2040
        response to external biotic stimulus 1274
          response to other organism 1271
            defense response to other organism 857
              defense response to symbiont 697
                innate immune response 639
                  regulation of innate immune response 395
                    positive regulation of innate immune response 324
                      activation of innate immune response 262
                        innate immune response-activating signaling pathway 248
                          pattern recognition receptor signaling pathway 247
                            toll-like receptor signaling pathway 63
                              regulation of toll-like receptor signaling pathway 28
                                negative regulation of toll-like receptor signaling pathway + 19
                                positive regulation of toll-like receptor signaling pathway + 3
                                regulation of MyD88-dependent toll-like receptor signaling pathway + 4
                                regulation of MyD88-independent toll-like receptor signaling pathway + 1
                                regulation of toll-like receptor 21 signaling pathway + 0
paths to the root