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ONTOLOGY REPORT - ANNOTATIONS

Term:Slx1-Slx4 complex
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Accession:GO:0033557 term browser browse the term
Definition:A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.


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Slx1-Slx4 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit part_of ISO
IEA
IBA		 (PMID:19595721), (PMID:19596235), (PMID:19596236)
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:19595721 PMID:19596235 PMID:19596236 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit part_of ISO
IBA		 (PMID:19595721), (PMID:19596235), (PMID:19596236)
GO_REF:0000033		 RGD
GO_Central		 PMID:19595721 PMID:19596235 PMID:19596236 GO_REF:0000033 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20827
    protein-containing complex 6555
      nuclear protein-containing complex 1275
        Slx1-Slx4 complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20827
    cellular anatomical structure 20627
      organelle 13970
        intracellular organelle 13564
          intracellular membrane-bounded organelle 12005
            nucleus 7451
              nuclear lumen 4053
                nuclear chromosome 226
                  Slx1-Slx4 complex 2
paths to the root