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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear DNA replication
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Accession:GO:0033260 term browser browse the term
Definition:The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
Synonyms:exact_synonym: DNA replication involved in S phase;   nuclear cell cycle DNA replication
 related_synonym: DNA replication during S phase
 only_in_taxon: NCBITaxon:2759 ! Eukaryota



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nuclear DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:40,869,778...40,917,976
Ensembl chr 9:40,870,924...40,915,629
JBrowse link
G ZNF830 zinc finger protein 830 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21191184) Ensembl
MGI
PMID:21191184 GO_REF:0000107 NCBI chr 9:38,382,508...38,384,060
Ensembl chr 9:38,382,900...38,384,015
JBrowse link
DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 5:64,566,035...64,570,361
Ensembl chr 5:64,566,043...64,570,748
JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:22,796,558...22,805,961
Ensembl chr35:22,798,386...22,805,959
JBrowse link
DNA synthesis involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:15696186 RGD:2301349 NCBI chr10:300,863...306,546
Ensembl chr10:300,903...305,438
JBrowse link
G TK1 thymidine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:2,959,450...2,970,908
Ensembl chr 9:2,959,488...2,971,064
JBrowse link
mitotic DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:20,227,808...20,537,893
Ensembl chr  X:20,227,886...20,537,902
JBrowse link
mitotic DNA replication termination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTF2 replication termination factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr24:41,665,259...41,706,348
Ensembl chr24:41,665,294...41,706,348
JBrowse link
mitotic DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RECQL5 RecQ like helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,902,753...4,940,442
Ensembl chr 9:4,903,477...4,940,436
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
G RAD51 RAD51 recombinase involved_in IEA InterPro GO_REF:0000002 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606
JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:19,626,001...19,683,819
Ensembl chr 4:19,626,977...19,684,660
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:16,478,774...16,485,992
Ensembl chr24:16,478,769...16,484,992
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:24115439) BHF-UCL PMID:24115439 NCBI chr24:47,219,977...47,248,791 JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:2161540) Ensembl
MGI
PMID:2161540 GO_REF:0000107 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:59,772,067...60,107,016
Ensembl chr  X:59,774,585...60,106,980
JBrowse link
G CDC7 cell division cycle 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:57,336,165...57,362,478
Ensembl chr 6:57,337,407...57,362,757
JBrowse link
G DBF4B DBF4B-CDC7 kinase regulatory subunit involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chr 9:18,734,678...18,768,128 JBrowse link
G INO80 INO80 complex ATPase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:8,100,536...8,229,868
Ensembl chr30:8,101,934...8,202,025
JBrowse link
G WIZ WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chr20:46,746,991...46,773,065
Ensembl chr20:46,747,062...46,817,240
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15980864) Ensembl
MGI
PMID:15980864 GO_REF:0000107 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160
JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789
JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (PMID:11850834) MGI PMID:11850834 NCBI chr 5:64,566,035...64,570,361
Ensembl chr 5:64,566,043...64,570,748
JBrowse link
G DACH1 dachshund family transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:25,690,700...25,934,449
Ensembl chr22:25,726,597...25,934,550
JBrowse link
G ILKAP ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chr25:48,666,850...48,689,405
Ensembl chr25:48,666,849...48,689,381
JBrowse link
G NUGGC nuclear GTPase, germinal center associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:29,507,198...29,561,565
Ensembl chr25:29,520,921...29,561,349
JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UPF1 UPF1 RNA helicase and ATPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,234,411...44,271,129
Ensembl chr20:44,236,264...44,270,916
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17101
    cellular process 16595
      cell cycle process 1196
        cell cycle DNA replication 31
          nuclear DNA replication 26
            DNA replication preinitiation complex assembly + 2
            DNA strand elongation involved in nuclear cell cycle DNA replication + 0
            mitotic DNA replication + 9
            negative regulation of nuclear cell cycle DNA replication + 0
            nuclear DNA replication DNA duplex unwinding + 0
            nuclear DNA replication DNA ligation + 0
            nuclear DNA replication termination + 1
            nuclear cell cycle DNA replication initiation + 1
            positive regulation of nuclear cell cycle DNA replication + 6
            pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 0
            premeiotic DNA replication + 0
            regulation of nuclear cell cycle DNA replication + 12
            telomere maintenance via semi-conservative replication + 4
Path 2
Term Annotations click to browse term
  biological_process 17101
    cellular process 16595
      metabolic process 10708
        primary metabolic process 9413
          nucleobase-containing compound metabolic process 5142
            nucleic acid metabolic process 4583
              DNA metabolic process 888
                DNA replication 256
                  DNA-templated DNA replication 143
                    cell cycle DNA replication 31
                      nuclear DNA replication 26
                        DNA replication preinitiation complex assembly + 2
                        DNA strand elongation involved in nuclear cell cycle DNA replication + 0
                        mitotic DNA replication + 9
                        negative regulation of nuclear cell cycle DNA replication + 0
                        nuclear DNA replication DNA duplex unwinding + 0
                        nuclear DNA replication DNA ligation + 0
                        nuclear DNA replication termination + 1
                        nuclear cell cycle DNA replication initiation + 1
                        positive regulation of nuclear cell cycle DNA replication + 6
                        pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 0
                        premeiotic DNA replication + 0
                        regulation of nuclear cell cycle DNA replication + 12
                        telomere maintenance via semi-conservative replication + 4
paths to the root