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ONTOLOGY REPORT - ANNOTATIONS


Term:mast cell homeostasis
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Accession:GO:0033023 term browser browse the term
Definition:The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Comment:Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus.


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mast cell homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:29155995) UniProt PMID:29155995 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173
JBrowse link
mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034
JBrowse link
G Kitlg KIT ligand acts_upstream_of ISO (PMID:12714518) MGI PMID:12714518 NCBI chrNW_004624837:7,456,116...7,541,764
Ensembl chrNW_004624837:7,456,120...7,541,730
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of ISO (PMID:15039234) MGI PMID:15039234 NCBI chrNW_004624875:3,636,762...3,959,991
Ensembl chrNW_004624875:3,636,924...3,956,576
JBrowse link
negative regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (PMID:12714518) MGI PMID:12714518 NCBI chrNW_004624837:7,456,116...7,541,764
Ensembl chrNW_004624837:7,456,120...7,541,730
JBrowse link
positive regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:15039234) MGI PMID:15039234 NCBI chrNW_004624875:3,636,762...3,959,991
Ensembl chrNW_004624875:3,636,924...3,956,576
JBrowse link
regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:14625290) BHF-UCL PMID:14625290 NCBI chrNW_004624969:212,089...254,532
Ensembl chrNW_004624969:212,321...253,328
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15135
    immune system process 2155
      leukocyte homeostasis 123
        mast cell homeostasis 5
          mast cell apoptotic process + 4
Path 2
Term Annotations click to browse term
  biological_process 15135
    homeostatic process 1788
      multicellular organismal-level homeostasis 880
        homeostasis of number of cells 390
          leukocyte homeostasis 123
            mast cell homeostasis 5
              mast cell apoptotic process + 4
paths to the root