Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:lamellipodium assembly
go back to main search page
Accession:GO:0030032 term browser browse the term
Definition:Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:exact_synonym: lamellipodium biosynthesis;   lamellipodium formation
 related_synonym: lamellipodium biogenesis


show annotations for term's descendants           Sort by:
lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABLIM1 actin binding LIM protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22684256) MGI
TreeGrafter
Ensembl		 PMID:22684256 GO_REF:0000107 GO_REF:0000118 NCBI chr10:111,030,953...111,360,527
Ensembl chr10:114,465,838...114,712,561 		JBrowse link
G ABLIM2 actin binding LIM protein family member 2 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 4:8,031,074...8,224,912 JBrowse link
G ABLIM3 actin binding LIM protein family member 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22684256) MGI
TreeGrafter
Ensembl		 PMID:22684256 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:144,568,394...144,686,983
Ensembl chr 5:150,576,604...150,697,271 		JBrowse link
G AJUBA ajuba LIM protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728191) Ensembl
MGI		 PMID:15728191 GO_REF:0000107 NCBI chr14:3,791,309...3,802,763
Ensembl chr14:21,889,443...21,900,700 		JBrowse link
G ARHGEF4 Rho guanine nucleotide exchange factor 4 involved_in ISO (PMID:17599059) UniProt PMID:17599059 NCBI chr2B:29,583,389...29,716,630
Ensembl chr2B:131,594,345...131,800,705 		JBrowse link
G ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor 6 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:125,794,158...125,909,809
Ensembl chr  X:136,058,879...136,176,110 		JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:92,246,107...92,436,173
Ensembl chr13:111,427,905...111,545,413 		JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15294161) Ensembl
MGI		 PMID:15294161 GO_REF:0000107 NCBI chr 1:18,297,434...18,444,011
Ensembl chr 1:19,344,154...19,488,133 		JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092 		JBrowse link
G CCDC88A coiled-coil domain containing 88A involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:55,445,060...55,576,479
Ensembl chr2A:56,589,221...56,715,362 		JBrowse link
G CDH13 cadherin 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,255,482...64,418,053
Ensembl chr16:82,883,184...83,808,996 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14765121) Ensembl
MGI		 PMID:14765121 GO_REF:0000107 Ensembl chr15:20,462,811...20,573,684 JBrowse link
G DMTN dematin actin binding protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 acts_upstream_of_or_within ISO (PMID:11527409) MGI PMID:11527409 NCBI chr12:53,574,573...53,822,971
Ensembl chr12:56,181,565...56,421,810 		JBrowse link
G GOLPH3 golgi phosphoprotein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:78,157,724...78,215,933
Ensembl chr 5:83,536,242...83,596,639 		JBrowse link
G ITGB1 integrin subunit beta 1 involved_in ISO PMID:20091784 ARUK-UCL PMID:20091784 RGD:6480646 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12808099) Ensembl
MGI		 PMID:12808099 GO_REF:0000107 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12808099) Ensembl
MGI		 PMID:12808099 GO_REF:0000107 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363 		JBrowse link
G NCKAP1 NCK associated protein 1 acts_upstream_of_or_within ISO (PMID:16831833)
(PMID:14765121)		 MGI PMID:14765121 PMID:16831833 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710 		JBrowse link
G NUP85 nucleoporin 85 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15995708) Ensembl
MGI		 PMID:15995708 GO_REF:0000107 NCBI chr17:69,152,452...69,182,688
Ensembl chr17:74,708,654...74,735,628 		JBrowse link
G P2RY12 purinergic receptor P2Y12 involved_in ISO PMID:20091784 ARUK-UCL PMID:20091784 RGD:6480646 NCBI chr 3:148,364,151...148,412,231 JBrowse link
G PARVB parvin beta involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:24,913,710...25,061,603
Ensembl chr22:43,079,786...43,245,932 		JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (PMID:25429154) MGI PMID:25429154 NCBI chr17:36,389,549...36,425,161
Ensembl chr17:41,038,302...41,073,872 		JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,329,314...15,594,787
Ensembl chr12:15,725,917...15,990,532 		JBrowse link
G PXN paxillin acts_upstream_of_or_within ISO (PMID:14636584) MGI PMID:14636584 NCBI chr12:117,785,614...117,840,816
Ensembl chr12:121,160,295...121,176,667 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:9312003)
(PMID:15728191)		 UniProt
MGI		 PMID:9312003 PMID:15728191 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RHOD ras homolog family member D involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,418,466...62,433,453
Ensembl chr11:65,736,668...65,754,761 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987 		JBrowse link
G SH2B1 SH2B adaptor protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11786545) Ensembl
MGI		 PMID:11786545 GO_REF:0000107 Ensembl chr16:29,249,597...29,263,334 JBrowse link
G SPATA13 spermatogenesis associated 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:5,298,466...5,626,162
Ensembl chr13:23,837,412...23,921,025 		JBrowse link
G SPEF1 sperm flagellar 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,858,548...3,863,150
Ensembl chr20:3,615,358...3,619,390 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728722) Ensembl
MGI		 PMID:15728722 GO_REF:0000107 NCBI chr 9:104,883,197...105,115,143
Ensembl chr 9:133,494,481...133,668,036 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728722) Ensembl
MGI		 PMID:15728722 GO_REF:0000107 NCBI chr 1:110,101,651...110,531,294
Ensembl chr 1:109,210,813...109,617,658 		JBrowse link
G VCL vinculin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12473693) Ensembl
MGI		 PMID:12473693 GO_REF:0000107 NCBI chr10:70,521,259...70,641,917
Ensembl chr10:73,191,375...73,311,296 		JBrowse link
G WASF2 WASP family member 2 acts_upstream_of_or_within ISO (PMID:12879075) MGI PMID:12879075 NCBI chr 1:26,665,853...26,750,618
Ensembl chr 1:27,717,538...27,737,316 		JBrowse link
G WASF3 WASP family member 3 acts_upstream_of_or_within ISO (PMID:16723544) MGI PMID:16723544 NCBI chr13:7,849,687...7,980,979
Ensembl chr13:26,250,171...26,328,553 		JBrowse link
G WHAMM WASP homolog associated with actin, golgi membranes and microtubules involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:62,763,534...62,788,639
Ensembl chr15:80,706,760...80,730,006 		JBrowse link
lamellipodium assembly involved in ameboidal cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:181,808,318...182,064,583
Ensembl chr 1:186,092,113...186,346,019 		JBrowse link
negative regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI3 ABI family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,381,551...8,394,537
Ensembl chr17:8,364,561...8,376,930 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24093776 RGD:11570550 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806 		JBrowse link
G HRG histidine rich glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,701,069...183,712,365
Ensembl chr 3:192,168,299...192,180,539 		JBrowse link
G PLXNB3 plexin B3 involved_in ISO PMID:20696765 UniProt PMID:20696765 RGD:8554409 NCBI chr  X:143,314,794...143,330,066
Ensembl chr  X:153,200,971...153,215,909 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656 		JBrowse link
positive regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) ARUK-UCL PMID:21107423 NCBI chr2B:90,561,708...90,663,072
Ensembl chr2B:208,702,092...208,797,499 		JBrowse link
G ACTR2 actin related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:65,289,675...65,333,219
Ensembl chr2A:66,413,011...66,456,857 		JBrowse link
G ACTR3 actin related protein 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18256280 GO_REF:0000107 RGD:2306202 NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729 		JBrowse link
G AKIRIN1 akirin 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:38,269,096...38,283,920
Ensembl chr 1:39,616,036...39,629,300 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:19539607 RGD:2316079 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15252126 GO_REF:0000107 RGD:2306210 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:20671235 RGD:11341707 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756 		JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 involved_in ISO (PMID:25533347) UniProt PMID:25533347 NCBI chr 7:64,822,964...66,015,831
Ensembl chr 7:77,495,909...78,686,763 		JBrowse link
G AVIL advillin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,108,569...31,129,307
Ensembl chr12:31,369,872...31,389,847 		JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,051,054...10,062,364
Ensembl chr 3:10,403,896...10,415,545 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709 		JBrowse link
G CDC42 cell division cycle 42 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806 		JBrowse link
G CLRN1 clarin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19423712) MGI
Ensembl		 PMID:19423712 GO_REF:0000107 NCBI chr 3:147,954,124...148,000,895
Ensembl chr 3:155,526,011...155,573,684 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:20,462,811...20,573,684 JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14617821 RGD:9685179 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478 		JBrowse link
G FRMD7 FERM domain containing 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23967341) Ensembl
MGI		 PMID:23967341 GO_REF:0000107 NCBI chr  X:121,208,961...121,259,708
Ensembl chr  X:131,516,484...131,567,394 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in ISO (PMID:9571235) UniProt PMID:9571235 NCBI chr 7:5,848,902...5,862,756 JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:15302889 RGD:2316937 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723 		JBrowse link
G LOC100986336 twinfilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743 		JBrowse link
G MSTN myostatin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15467718) Ensembl
MGI		 PMID:15467718 GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
G NCKAP1 NCK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710 		JBrowse link
G OCLN occludin involved_in ISO (PMID:20152177) ARUK-UCL PMID:20152177 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960 		JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:90,731,695...91,065,846
Ensembl chr10:94,278,550...94,575,024 		JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:15467718)
(PMID:19625648), (PMID:8625410)		 RGD
MGI
UniProt		 PMID:8625410 PMID:12105187 PMID:15467718 PMID:19625648 RGD:1299247 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026 		JBrowse link
G WASF2 WASP family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,665,853...26,750,618
Ensembl chr 1:27,717,538...27,737,316 		JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583 		JBrowse link
regulation of lamellipodium assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN3 bridging integrator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23872330) Ensembl
MGI		 PMID:23872330 GO_REF:0000107 NCBI chr 8:21,870,784...21,919,077
Ensembl chr 8:18,809,582...18,858,912 		JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:18,297,434...18,444,011
Ensembl chr 1:19,344,154...19,488,133 		JBrowse link
G CDC42 cell division cycle 42 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G DMTN dematin actin binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229 		JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787 		JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:104,099,620...104,548,077
Ensembl chr 5:109,964,823...110,350,576 		JBrowse link
G LOC100986336 twinfilin-2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404 		JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      cellular component organization or biogenesis 6716
        cellular component organization 6518
          cell projection organization 1792
            plasma membrane bounded cell projection organization 1764
              lamellipodium organization 95
                lamellipodium assembly 75
                  lamellipodium assembly involved in ameboidal cell migration + 1
                  negative regulation of lamellipodium assembly 5
                  positive regulation of lamellipodium assembly 31
                  regulation of lamellipodium assembly + 42
paths to the root