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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of low-density lipoprotein particle clearance
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Accession:GO:0010989 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


show annotations for term's descendants           Sort by:
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23828271 RGD:12792253 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IBA		 (PMID:15778093)
GO_REF:0000033		 RGD
GO_Central		 PMID:15778093 GO_REF:0000033 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Il19 interleukin 19 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO RNAcentral:URS00004176D4_9606 (PMID:26523989) RGD PMID:26523989 NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO
IEA		 (PMID:17452316)
GO_REF:0000107		 RGD
Ensembl		 PMID:17452316 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365) RGD PMID:26437365 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) RGD PMID:23285084 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of
involved_in		 ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:24296663)
(PMID:26523989)		 RGD PMID:24296663 PMID:26523989 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:26163491) RGD PMID:26163491 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:26318398) RGD PMID:26318398 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) RGD PMID:26520906 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180 		JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (PMID:19520913) RGD PMID:19520913 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821), (PMID:22848640) RGD PMID:17328821 PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    multicellular organismal process 8904
      plasma lipoprotein particle clearance 48
        low-density lipoprotein particle clearance 33
          negative regulation of low-density lipoprotein particle clearance 16
Path 2
Term Annotations click to browse term
  biological_process 20075
    biological regulation 13559
      regulation of biological process 13136
        regulation of plasma lipoprotein particle levels 80
          plasma lipoprotein particle clearance 48
            low-density lipoprotein particle clearance 33
              regulation of low-density lipoprotein particle clearance 24
                negative regulation of low-density lipoprotein particle clearance 16
paths to the root