Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of G2/M transition of mitotic cell cycle
go back to main search page
Accession:GO:0010972 term browser browse the term
Definition:Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
Synonyms:exact_synonym: negative regulation of mitotic entry

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
negative regulation of G2/M transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 ISO RGD PMID:11278490 RGD:2316109 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Fhl1 four and a half LIM domains 1 involved_in ISO (PMID:21702045) UniProt PMID:21702045 NCBI chrNW_004955489:8,888,845...8,944,778
Ensembl chrNW_004955489:8,888,779...8,901,970 		JBrowse link
G Gpr132 G protein-coupled receptor 132 involved_in ISO (PMID:9770487) CACAO PMID:9770487 NCBI chrNW_004955538:3,366,333...3,382,778 JBrowse link
G Pinx1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:11701125) BHF-UCL PMID:11701125 NCBI chrNW_004955403:52,284,378...52,361,924
Ensembl chrNW_004955403:52,284,166...52,362,206 		JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 involved_in ISO (PMID:9268380) UniProt PMID:9268380 NCBI chrNW_004955442:14,368,110...14,372,365
Ensembl chrNW_004955442:14,364,031...14,372,365 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in ISO (PMID:10375619) CAFA PMID:10375619 NCBI chrNW_004955417:22,941,549...22,966,395
Ensembl chrNW_004955417:22,941,479...22,966,837 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 involved_in ISO (PMID:19966869) UniProt PMID:19966869 NCBI chrNW_004955414:27,357,602...27,462,481
Ensembl chrNW_004955414:27,357,602...27,462,731 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase involved_in ISO (PMID:7743995), (PMID:8348613), (PMID:8428596) UniProt PMID:7743995 PMID:8348613 PMID:8428596 NCBI chrNW_004955414:25,281,725...25,299,242
Ensembl chrNW_004955414:25,281,689...25,298,096 		JBrowse link
mitotic cytokinesis checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp4c charged multivesicular body protein 4C involved_in ISO (PMID:22422861), (PMID:24814515) UniProt PMID:22422861 PMID:24814515 NCBI chrNW_004955417:96,674...135,601
Ensembl chrNW_004955417:96,865...137,739 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:24814515) UniProt PMID:24814515 NCBI chrNW_004955484:7,368,938...7,375,964
Ensembl chrNW_004955484:7,368,938...7,375,969 		JBrowse link
G Zfyve19 zinc finger FYVE-type containing 19 involved_in ISO (PMID:24814515) UniProt PMID:24814515 NCBI chrNW_004955416:7,672,499...7,679,851
Ensembl chrNW_004955416:7,672,592...7,679,632 		JBrowse link
mitotic DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clspn claspin involved_in ISO (PMID:16885022) UniProt PMID:16885022 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 involved_in ISO (PMID:10722740) UniProt PMID:10722740 NCBI chrNW_004955433:23,333,797...23,358,255
Ensembl chrNW_004955433:23,333,742...23,358,579 		JBrowse link
G Znf830 zinc finger protein 830 involved_in ISO (PMID:21191184) UniProt PMID:21191184 NCBI chrNW_004955481:9,661,791...9,663,326
Ensembl chrNW_004955481:9,661,830...9,662,918 		JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004955474:6,252,321...6,265,518
Ensembl chrNW_004955474:6,252,321...6,265,286 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:15149599) BHF-UCL PMID:15149599 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISO (PMID:19261746), (PMID:19261748), (PMID:19261749) UniProt PMID:19261746 PMID:19261748 PMID:19261749 NCBI chrNW_004955524:939,250...944,457
Ensembl chrNW_004955524:937,815...944,456 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO (PMID:19261748) UniProt PMID:19261748 NCBI chrNW_004955469:9,831,488...10,246,631
Ensembl chrNW_004955469:9,831,488...10,246,899 		JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) UniProt PMID:11309417 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProt PMID:17525341 PMID:19261746 PMID:19261748 NCBI chrNW_004955594:551,407...613,772
Ensembl chrNW_004955594:554,081...613,661 		JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO (PMID:15150265) UniProt PMID:15150265 NCBI chrNW_004955567:924,728...943,092
Ensembl chrNW_004955567:924,734...943,701 		JBrowse link
G Ccng1 cyclin G1 ISO RGD PMID:9464250 RGD:2316029 NCBI chrNW_004955408:16,846,050...16,850,365 JBrowse link
G Cdc14b cell division cycle 14B involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955422:23,303,472...23,445,785
Ensembl chrNW_004955422:23,303,250...23,322,493 		JBrowse link
G Cdk1 cyclin dependent kinase 1 acts_upstream_of_or_within ISO (PMID:12937170) MGI PMID:12937170 NCBI chrNW_004955425:14,210,681...14,226,474
Ensembl chrNW_004955425:14,210,680...14,226,474 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:15790566) UniProt PMID:15790566 NCBI chrNW_004955451:13,160,811...13,170,012
Ensembl chrNW_004955451:13,120,761...13,170,073 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) UniProt PMID:23213251 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:20932473) UniProt PMID:20932473 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Clspn claspin involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955452:13,801,073...13,842,387
Ensembl chrNW_004955452:13,802,285...13,833,735 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955422:1,702,131...1,734,603
Ensembl chrNW_004955422:1,700,692...1,734,773 		JBrowse link
G CUNH10orf90 chromosome unknown C10orf90 homolog involved_in ISO (PMID:20154723) UniProt PMID:20154723 NCBI chrNW_004955477:4,299,277...4,510,702
Ensembl chrNW_004955477:4,297,588...4,510,959 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO (PMID:17085480) UniProt PMID:17085480 NCBI chrNW_004955406:5,256,057...5,299,573
Ensembl chrNW_004955406:5,254,558...5,299,573 		JBrowse link
G Foxn3 forkhead box N3 involved_in ISO (PMID:9154802) UniProt PMID:9154802 NCBI chrNW_004955438:11,720,563...12,126,185
Ensembl chrNW_004955438:11,720,570...12,126,185 		JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within ISO (PMID:12048180) MGI PMID:12048180 NCBI chrNW_004955475:10,666,024...10,673,717
Ensembl chrNW_004955475:10,665,987...10,674,110 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955495:5,481,914...5,503,690
Ensembl chrNW_004955495:5,481,916...5,505,521 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:20467439) MGI PMID:20467439 NCBI chrNW_004955583:730,353...731,301
Ensembl chrNW_004955583:730,289...731,260 		JBrowse link
G Mbd4 methyl-CpG binding domain 4, DNA glycosylase acts_upstream_of_or_within ISO (PMID:14614141) MGI PMID:14614141 NCBI chrNW_004955429:17,858,656...17,868,111
Ensembl chrNW_004955429:17,858,937...17,869,262 		JBrowse link
G Mbtps1 membrane bound transcription factor peptidase, site 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955564:176,230...226,555
Ensembl chrNW_004955564:176,230...228,587 		JBrowse link
G Mbtps2 membrane bound transcription factor peptidase, site 2 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chrNW_004955509:2,185,054...2,222,497
Ensembl chrNW_004955509:2,184,522...2,222,505 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chrNW_004955408:726,124...758,851 JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within		 ISO (PMID:11438675)
(PMID:18614044)		 UniProt
MGI		 PMID:11438675 PMID:18614044 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) UniProt PMID:21741933 NCBI chrNW_004955574:1,505,997...1,514,680
Ensembl chrNW_004955574:1,506,022...1,517,130 		JBrowse link
G Plk1 polo like kinase 1 involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chrNW_004955493:2,206,353...2,217,231
Ensembl chrNW_004955493:2,206,353...2,217,231 		JBrowse link
G Rint1 RAD50 interactor 1 involved_in ISO (PMID:11096100) BHF-UCL PMID:11096100 NCBI chrNW_004955410:10,121,322...10,144,748
Ensembl chrNW_004955410:10,121,219...10,144,748 		JBrowse link
G Syf2 SYF2 pre-mRNA splicing factor acts_upstream_of_or_within ISO (PMID:22448250) MGI PMID:22448250 NCBI chrNW_004955452:4,850,049...4,856,647
Ensembl chrNW_004955452:4,848,659...4,857,114 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955481:3,698,686...3,836,209
Ensembl chrNW_004955481:3,705,202...3,772,116 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955493:6,968,537...6,986,608
Ensembl chrNW_004955493:6,969,096...6,985,878 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO (PMID:17396146) UniProt PMID:17396146 NCBI chrNW_004955455:13,020,618...13,207,539
Ensembl chrNW_004955455:13,103,357...13,211,315 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 NCBI chrNW_004955408:29,154,373...29,274,817
Ensembl chrNW_004955408:29,154,629...29,274,856 		JBrowse link
mitotic G2/M transition checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase involved_in ISO (PMID:30139873) UniProt PMID:30139873 NCBI chrNW_004955508:3,337,036...3,440,313
Ensembl chrNW_004955508:3,337,432...3,440,257 		JBrowse link
G Brca1 BRCA1 DNA repair associated acts_upstream_of_or_within ISO (PMID:15254237) MGI PMID:15254237 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:19223857) UniProt PMID:19223857 NCBI chrNW_004955451:13,160,811...13,170,012
Ensembl chrNW_004955451:13,120,761...13,170,073 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:33108758)
(PMID:9278511)		 UniProt PMID:9278511 PMID:33108758 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:18172500), (PMID:19182791) UniProt PMID:18172500 PMID:19182791 NCBI chrNW_004955482:233,485...267,064
Ensembl chrNW_004955482:233,486...267,064 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:30139873) UniProt PMID:30139873 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007 		JBrowse link
G Inip INTS3 and NABP interacting protein involved_in ISO (PMID:19683501) ComplexPortal PMID:19683501 NCBI chrNW_004955419:14,729,275...14,732,971
Ensembl chrNW_004955419:14,728,816...14,732,971 		JBrowse link
G Ints3 integrator complex subunit 3 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955545:352,170...394,751
Ensembl chrNW_004955545:351,872...396,052 		JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955403:7,603,002...7,610,925
Ensembl chrNW_004955403:7,604,144...7,611,042 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO (PMID:19683501) UniProt PMID:19683501 NCBI chrNW_004955458:3,835,205...3,836,841
Ensembl chrNW_004955458:3,835,205...3,840,634 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO (PMID:33108758) UniProt PMID:33108758 NCBI chrNW_004955434:4,250,105...4,251,508 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      cell cycle process 1065
        cell cycle phase transition 444
          mitotic cell cycle phase transition 353
            G2/M transition of mitotic cell cycle 119
              negative regulation of G2/M transition of mitotic cell cycle 56
                mitotic G2 cell size control checkpoint signaling 0
                mitotic G2/M transition checkpoint + 46
                mitotic cytokinesis checkpoint signaling 3
Path 2
Term Annotations click to browse term
  biological_process 12572
    biological regulation 9067
      regulation of biological process 8766
        regulation of cellular process 8474
          regulation of cell cycle 912
            regulation of cell cycle process 637
              regulation of cell cycle phase transition 348
                regulation of mitotic cell cycle phase transition 265
                  regulation of G2/M transition of mitotic cell cycle 88
                    negative regulation of G2/M transition of mitotic cell cycle 56
                      mitotic G2 cell size control checkpoint signaling 0
                      mitotic G2/M transition checkpoint + 46
                      mitotic cytokinesis checkpoint signaling 3
paths to the root