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ONTOLOGY REPORT - ANNOTATIONS

Term:Notch signaling pathway
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Accession:GO:0007219 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: N signaling pathway;   N signalling pathway;   Notch receptor signaling pathway;   Notch receptor signalling pathway;   Notch signalling pathway
 alt_id: GO:0030179
 xref: Wikipedia:Notch_signaling_pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi


show annotations for term's descendants           Sort by:
Notch signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 involved_in IEA Ensembl
UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr15:37,562,930...37,717,175
Ensembl chr15:55,873,606...56,027,188 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000118 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G AGXT alanine--glyoxylate aminotransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr2B:128,125,289...128,137,091
Ensembl chr2B:246,928,784...246,939,837 		JBrowse link
G ANGPT4 angiopoietin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr20:1,045,581...1,086,669
Ensembl chr20:815,894...854,235 		JBrowse link
G ANXA4 annexin A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr2A:69,686,651...69,869,340
Ensembl chr2A:70,902,260...70,986,917 		JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:125,610,649...125,614,261
Ensembl chr 1:129,262,002...129,265,810 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr15:42,224,593...42,256,202
Ensembl chr15:60,520,031...60,551,599 		JBrowse link
G APP amyloid beta precursor protein involved_in IEA UniProt GO_REF:0000043 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11073877)
(PMID:15976074)		 Ensembl
MGI		 PMID:11073877 PMID:15976074 GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
G ATOH1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr 4:86,188,534...86,191,301
Ensembl chr 4:96,863,762...96,864,832 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16314491) Ensembl
MGI		 PMID:16314491 GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G CCDC85C coiled-coil domain containing 85C acts_upstream_of_or_within ISO (PMID:37352102) MGI PMID:37352102 NCBI chr14:80,134,889...80,229,717 JBrowse link
G CDH6 cadherin 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr 5:79,013,970...79,152,645
Ensembl chr 5:84,398,474...84,456,013 		JBrowse link
G CDK6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (PMID:21508411) MGI PMID:21508411 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha acts_upstream_of_or_within ISO (PMID:25446530) MGI PMID:25446530 NCBI chr19:30,223,567...30,226,204 JBrowse link
G CFAP58 cilia and flagella associated protein 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:100,905,434...101,056,560
Ensembl chr10:104,412,171...104,514,920 		JBrowse link
G CFD complement factor D ISO RGD PMID:12949072 RGD:1298875
G CTBP1 C-terminal binding protein 1 acts_upstream_of_or_within ISO (PMID:34435359) MGI PMID:34435359 NCBI chr 4:1,354,806...1,393,244
Ensembl chr 4:1,238,984...1,266,822 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:81,348,380...81,356,607
Ensembl chr14:100,654,965...100,668,019 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24667410) InterPro
MGI
UniProt
Ensembl		 PMID:24667410 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471 		JBrowse link
G DLX1 distal-less homeobox 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23042297) Ensembl
MGI		 PMID:23042297 GO_REF:0000107 NCBI chr2B:59,382,156...59,387,100
Ensembl chr2B:176,839,721...176,843,909 		JBrowse link
G DLX2 distal-less homeobox 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23042297) Ensembl
MGI		 PMID:23042297 GO_REF:0000107 NCBI chr2B:59,396,841...59,400,297
Ensembl chr2B:176,853,913...176,857,079 		JBrowse link
G DNER delta/notch like EGF repeat containing involved_in IEA UniProt GO_REF:0000043 NCBI chr2B:116,604,193...116,963,026
Ensembl chr2B:235,409,108...235,642,161 		JBrowse link
G DTX1 deltex E3 ubiquitin ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11226752)
(PMID:15965470)		 InterPro
MGI
Ensembl
UniProt		 PMID:11226752 PMID:15965470 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr12:110,661,247...110,702,780
Ensembl chr12:114,046,700...114,085,372 		JBrowse link
G DTX2 deltex E3 ubiquitin ligase 2 acts_upstream_of_or_within ISO (PMID:11226752) MGI PMID:11226752 NCBI chr 7:67,509,102...67,537,030 JBrowse link
G DTX3 deltex E3 ubiquitin ligase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11226752) InterPro
MGI		 PMID:11226752 GO_REF:0000002 NCBI chr12:31,316,968...31,322,340
Ensembl chr12:31,577,001...31,579,669 		JBrowse link
G DTX3L deltex E3 ubiquitin ligase 3L involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:119,654,019...119,664,918
Ensembl chr 3:126,558,924...126,569,807 		JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:54,389,228...54,425,655
Ensembl chr11:57,839,228...57,874,337 		JBrowse link
G EPN1 epsin 1 acts_upstream_of_or_within ISO (PMID:19666558) MGI PMID:19666558 NCBI chr19:52,722,107...52,743,321
Ensembl chr19:61,408,695...61,427,647 		JBrowse link
G EPN2 epsin 2 acts_upstream_of_or_within ISO (PMID:19666558) MGI PMID:19666558 NCBI chr17:31,777,430...31,874,469
Ensembl chr17:36,942,381...37,038,509 		JBrowse link
G ETV2 ETS variant transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18462699) Ensembl
MGI		 PMID:18462699 GO_REF:0000107 NCBI chr19:32,571,829...32,575,083
Ensembl chr19:41,307,864...41,311,004 		JBrowse link
G FAT4 FAT atypical cadherin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26116661) Ensembl
MGI		 PMID:26116661 GO_REF:0000107 NCBI chr 4:117,494,842...117,674,382
Ensembl chr 4:128,637,516...128,814,407 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11425854) Ensembl
MGI		 PMID:11425854 GO_REF:0000107 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351 		JBrowse link
G FOXA1 forkhead box A1 acts_upstream_of_or_within ISO (PMID:25446530) MGI PMID:25446530 NCBI chr14:18,347,284...18,352,705 JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:25446530) MGI PMID:25446530 NCBI chr20:22,519,942...22,524,262 JBrowse link
G FOXC1 forkhead box C1 acts_upstream_of_or_within ISO (PMID:11562355) MGI PMID:11562355 NCBI chr 6:1,429,051...1,433,180 JBrowse link
G FOXC2 forkhead box C2 acts_upstream_of_or_within ISO (PMID:11562355) MGI PMID:11562355 NCBI chr16:67,237,476...67,239,545 JBrowse link
G GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 acts_upstream_of ISO (PMID:21943603) MGI PMID:21943603 NCBI chr11:70,494,185...70,585,921
Ensembl chr11:73,796,347...73,885,996 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178 		JBrowse link
G GRIP2 glutamate receptor interacting protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr 3:14,411,825...14,525,388
Ensembl chr 3:14,756,638...14,804,952 		JBrowse link
G GSX2 GS homeobox 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23042297) Ensembl
MGI		 PMID:23042297 GO_REF:0000107 NCBI chr 4:69,837,643...69,840,101
Ensembl chr 4:76,397,180...76,399,715 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:19682396), (PMID:19855400)
(PMID:17331197)
(PMID:25535395)		 UniProt
MGI		 PMID:17331197 PMID:19682396 PMID:19855400 PMID:25535395 NCBI chr 1:1,261,260...1,263,128 JBrowse link
G HES7 hes family bHLH transcription factor 7 acts_upstream_of_or_within ISO (PMID:11260262) MGI PMID:11260262 NCBI chr17:43,530,919...43,537,999 JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO
IEA		 RGD
UniProt
Ensembl		 PMID:11741889 GO_REF:0000043 GO_REF:0000107 RGD:70528 NCBI chr 8:76,286,433...76,290,507
Ensembl chr 8:77,913,761...77,921,201 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:11741889 GO_REF:0000107 RGD:70528 NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056 		JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:38,913,549...38,929,798
Ensembl chr 1:40,240,118...40,256,933 		JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (PMID:25446530) MGI PMID:25446530 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863 		JBrowse link
G HOXD3 homeobox D3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:63,432,720...63,452,816
Ensembl chr2B:181,141,538...181,161,604 		JBrowse link
G IFT172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21703454) Ensembl
MGI		 PMID:21703454 GO_REF:0000107 NCBI chr2A:27,448,139...27,492,302
Ensembl chr2A:27,536,534...27,580,406 		JBrowse link
G IFT74 intraflagellar transport 74 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21703454) Ensembl
MGI		 PMID:21703454 GO_REF:0000107 NCBI chr 9:26,802,459...26,912,292
Ensembl chr 9:27,415,565...27,514,558 		JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (PMID:21703454) MGI PMID:21703454 NCBI chr13:1,893,102...2,017,771
Ensembl chr13:20,206,471...20,331,204 		JBrowse link
G IL17A interleukin 17A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:21508411) MGI PMID:21508411 NCBI chr10:6,053,549...6,103,863 JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:25406395)
(PMID:15574878), (PMID:15845452), (PMID:24667410), (PMID:25446530)		 RGD
UniProt
TreeGrafter
MGI
Ensembl
InterPro		 PMID:15057910 PMID:15574878 PMID:15845452 PMID:24667410 PMID:25406395 More... GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:1334443 NCBI chr20:10,582,234...10,618,507
Ensembl chr20:10,582,094...10,618,383 		JBrowse link
G JAG2 jagged canonical Notch ligand 2 involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr14:85,785,586...85,812,056
Ensembl chr14:105,569,837...105,585,878 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 acts_upstream_of_or_within ISO (PMID:23117660) MGI PMID:23117660 NCBI chr12:5,165,057...5,168,307 JBrowse link
G KRT19 keratin 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr17:15,788,355...15,793,127
Ensembl chr17:16,006,608...16,010,782 		JBrowse link
G MAML1 mastermind like transcriptional coactivator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15019995) Ensembl
MGI		 PMID:15019995 GO_REF:0000107 NCBI chr 5:174,886,694...174,931,153
Ensembl chr 5:182,230,351...182,242,296 		JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 NCBI chr11:90,982,013...91,350,289
Ensembl chr11:94,511,873...94,873,977 		JBrowse link
G MAML3 mastermind like transcriptional coactivator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:132,082,120...132,518,928
Ensembl chr 4:143,391,606...143,562,699 		JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO (PMID:30560934) MGI PMID:30560934 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854 		JBrowse link
G MESP2 mesoderm posterior bHLH transcription factor 2 acts_upstream_of_or_within ISO (PMID:20346937)
(PMID:15902259)		 MGI PMID:15902259 PMID:20346937 NCBI chr15:68,470,528...68,473,209 JBrowse link
G MIB1 MIB E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16000382) Ensembl
TreeGrafter
MGI
UniProt		 PMID:16000382 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr18:14,944,432...15,113,313
Ensembl chr18:18,641,135...18,740,813 		JBrowse link
G MIB2 MIB E3 ubiquitin protein ligase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:379,326...395,041
Ensembl chr 1:1,539,634...1,557,517 		JBrowse link
G NCSTN nicastrin involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911 		JBrowse link
G NEUROD4 neuronal differentiation 4 acts_upstream_of_or_within ISO (PMID:15976074) MGI PMID:15976074 NCBI chr12:33,719,986...33,730,012 JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15845452) Ensembl
MGI		 PMID:15845452 GO_REF:0000107 NCBI chr14:16,155,331...16,158,588 JBrowse link
G NLE1 notchless homolog 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23231322)
(PMID:16611995)		 Ensembl
TreeGrafter
MGI		 PMID:16611995 PMID:23231322 GO_REF:0000107 GO_REF:0000118 NCBI chr17:21,643,865...21,654,169
Ensembl chr17:21,935,800...21,946,049 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:19154718)
(PMID:21419176)		 RGD
TreeGrafter
MGI
InterPro
UniProt
Ensembl		 PMID:15057910 PMID:19154718 PMID:21419176 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:1334443 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:34635817) UniProt
TreeGrafter
MGI
Ensembl
InterPro		 PMID:34635817 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840 		JBrowse link
G NOTCH3 notch receptor 3 involved_in ISO
IEA		 RGD
InterPro		 PMID:11925448 GO_REF:0000002 RGD:632418 NCBI chr19:14,692,571...14,733,758
Ensembl chr19:15,678,674...15,715,080 		JBrowse link
G NOTCH4 notch receptor 4 involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:31,842,233...31,871,412
Ensembl chr 6:32,722,112...32,750,978 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr 1:26,174,055...26,176,689
Ensembl chr 1:27,230,362...27,232,942 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
G NRARP NOTCH regulated ankyrin repeat protein involved_in
acts_upstream_of		 ISO (PMID:25985737)
(PMID:21998026)		 UniProt
MGI		 PMID:21998026 PMID:25985737 NCBI chr 9:108,358,959...108,361,586 JBrowse link
G NRIP2 nuclear receptor interacting protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr12:2,945,844...2,956,155
Ensembl chr12:2,879,690...2,887,722 		JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO (PMID:23117660) MGI PMID:23117660 NCBI chr 6:135,845,845...135,863,603
Ensembl chr 6:139,931,031...139,947,792 		JBrowse link
G PGAM2 phosphoglycerate mutase 2 acts_upstream_of_or_within ISO (PMID:23117660) MGI PMID:23117660 NCBI chr 7:44,776,722...44,780,248
Ensembl chr 7:44,843,067...44,845,984 		JBrowse link
G PLN phospholamban involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
G POFUT1 protein O-fucosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12697902) InterPro
UniProt
MGI
Ensembl		 PMID:12697902 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr20:28,496,987...28,527,817
Ensembl chr20:29,625,481...29,655,722 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10821758), (PMID:16715081)
(PMID:17698590)
(PMID:11262239)		 Ensembl
TreeGrafter
MGI
UniProt		 PMID:10821758 PMID:11262239 PMID:16715081 PMID:17698590 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17698590) UniProt
TreeGrafter
MGI		 PMID:17698590 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in IEA UniProt GO_REF:0000043 NCBI chr19:32,675,331...32,677,285
Ensembl chr19:41,409,662...41,411,089 		JBrowse link
G PTP4A3 protein tyrosine phosphatase 4A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr 8:138,062,418...138,108,281
Ensembl chr 8:141,166,898...141,188,314 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25406395)
(PMID:14701881)
(PMID:19154718)
(PMID:19124651)		 Ensembl
MGI
UniProt		 PMID:14701881 PMID:19124651 PMID:19154718 PMID:25406395 GO_REF:0000043 GO_REF:0000107 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683 		JBrowse link
G RCAN2 regulator of calcineurin 2 acts_upstream_of_or_within ISO (PMID:23117660) MGI PMID:23117660 NCBI chr 6:45,801,389...46,074,620
Ensembl chr 6:47,074,850...47,312,149 		JBrowse link
G RIPPLY1 ripply transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:20346937) MGI PMID:20346937 NCBI chr  X:95,998,718...96,003,843
Ensembl chr  X:106,377,932...106,381,193 		JBrowse link
G RIPPLY2 ripply transcriptional repressor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20346937) Ensembl
MGI		 PMID:20346937 GO_REF:0000107 NCBI chr 6:81,748,370...81,754,129
Ensembl chr 6:85,022,737...85,027,930 		JBrowse link
G RITA1 RBPJ interacting and tubulin associated 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr12:110,790,401...110,797,343
Ensembl chr12:114,173,173...114,180,288 		JBrowse link
G RPS19 ribosomal protein S19 acts_upstream_of_or_within ISO (PMID:25446530) MGI PMID:25446530 NCBI chr19:38,748,604...38,760,055
Ensembl chr19:47,254,157...47,264,953 		JBrowse link
G S1PR3 sphingosine-1-phosphate receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr 9:60,080,189...60,094,311
Ensembl chr 9:88,126,476...88,137,333 		JBrowse link
G SIX1 SIX homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,250,512...41,256,567
Ensembl chr14:59,515,324...59,527,494 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,321,075...46,328,865
Ensembl chr20:47,384,818...47,390,733 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904 		JBrowse link
G SNED1 sushi, nidogen and EGF like domains 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr2B:128,253,888...128,351,819
Ensembl chr2B:247,085,509...247,144,421 		JBrowse link
G SORBS2 sorbin and SH3 domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23117660) MGI
TreeGrafter		 PMID:23117660 GO_REF:0000118 NCBI chr 4:177,751,089...178,125,937
Ensembl chr 4:189,965,729...190,070,543 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of ISO (PMID:16631155) MGI PMID:16631155 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:25446530) MGI PMID:25446530 NCBI chr17:66,028,737...66,034,122 JBrowse link
G SUSD5 sushi domain containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
TreeGrafter
MGI		 PMID:23117660 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:33,078,312...33,142,135
Ensembl chr 3:33,380,733...33,443,438 		JBrowse link
G TBX2 T-box transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr17:55,501,932...55,511,537
Ensembl chr17:60,622,098...60,630,189 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25446530) Ensembl
MGI		 PMID:25446530 GO_REF:0000107 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23117660) Ensembl
MGI		 PMID:23117660 GO_REF:0000107 NCBI chr 3:12,079,195...12,087,485
Ensembl chr 3:12,425,429...12,433,192 		JBrowse link
G TMEM100 transmembrane protein 100 acts_upstream_of_or_within ISO (PMID:22783020) MGI PMID:22783020 NCBI chr17:49,802,649...49,808,568 JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22274697) Ensembl
MGI		 PMID:22274697 GO_REF:0000107 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104 		JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:1,013,831...1,036,486
Ensembl chr16:2,266,194...2,279,031 		JBrowse link
G TSPEAR thrombospondin type laminin G domain and EAR repeats involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27736875) Ensembl
MGI		 PMID:27736875 GO_REF:0000107 NCBI chr21:30,791,051...31,005,330
Ensembl chr21:44,087,591...44,299,041 		JBrowse link
G TTYH1 tweety family member 1 acts_upstream_of_or_within ISO (PMID:31079925) MGI PMID:31079925 NCBI chr19:51,362,145...51,383,512
Ensembl chr19:60,202,250...60,222,789 		JBrowse link
G WDR12 WD repeat domain 12 acts_upstream_of_or_within ISO (PMID:11827460) MGI PMID:11827460 NCBI chr2B:90,112,037...90,145,520
Ensembl chr2B:208,260,696...208,291,783 		JBrowse link
G XIRP1 xin actin binding repeat containing 1 acts_upstream_of_or_within ISO (PMID:23117660) MGI PMID:23117660 NCBI chr 3:39,079,712...39,089,098 JBrowse link
G ZNF423 zinc finger protein 423 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:29,748,405...30,118,999
Ensembl chr16:48,639,118...48,969,727 		JBrowse link
negative regulation of Notch signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ARRDC1 arrestin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,711,276...108,720,942
Ensembl chr 9:137,664,787...137,668,688 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23160044) Ensembl
MGI		 PMID:23160044 GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G BEND6 BEN domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23571214) Ensembl
TreeGrafter
MGI
InterPro		 PMID:23571214 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:56,513,496...56,586,227
Ensembl chr 6:58,144,948...58,216,965 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16324690) Ensembl
MGI		 PMID:16324690 GO_REF:0000107 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021 		JBrowse link
G CBFA2T2 CBFA2/RUNX1 partner transcriptional co-repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:29,780,902...29,937,398
Ensembl chr20:31,002,486...31,072,929 		JBrowse link
G CCNC cyclin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:97,383,290...97,410,068
Ensembl chr 6:101,265,499...101,292,233 		JBrowse link
G CDK3 cyclin dependent kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:69,947,125...69,952,567
Ensembl chr17:75,498,134...75,503,448 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,895,554...19,898,672
Ensembl chr15:38,145,730...38,148,698 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21419176) Ensembl
MGI		 PMID:21419176 GO_REF:0000107 NCBI chr14:81,348,380...81,356,607
Ensembl chr14:100,654,965...100,668,019 		JBrowse link
G DLK2 delta like non-canonical Notch ligand 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21419176) Ensembl
MGI		 PMID:21419176 GO_REF:0000107 NCBI chr 6:43,042,368...43,048,661
Ensembl chr 6:44,333,540...44,339,963 		JBrowse link
G DLL3 delta like canonical Notch ligand 3 ISO RGD PMID:16144902 RGD:1599776 NCBI chr19:36,597,420...36,607,021 JBrowse link
G DLL4 delta like canonical Notch ligand 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471 		JBrowse link
G DLX1 distal-less homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23042297) Ensembl
MGI		 PMID:23042297 GO_REF:0000107 NCBI chr2B:59,382,156...59,387,100
Ensembl chr2B:176,839,721...176,843,909 		JBrowse link
G DLX2 distal-less homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23042297) Ensembl
MGI		 PMID:23042297 GO_REF:0000107 NCBI chr2B:59,396,841...59,400,297
Ensembl chr2B:176,853,913...176,857,079 		JBrowse link
G EGFL7 EGF like domain multiple 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20947685) MGI
Ensembl		 PMID:20947685 GO_REF:0000107 NCBI chr 9:107,735,192...107,748,729
Ensembl chr 9:136,708,783...136,722,448 		JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16672344) MGI
Ensembl		 PMID:16672344 GO_REF:0000107 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035 		JBrowse link
G GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 acts_upstream_of_or_within
involved_in		 ISO (PMID:21943603), (PMID:22951639) MGI
CACAO		 PMID:21943603 PMID:22951639 NCBI chr11:70,494,185...70,585,921
Ensembl chr11:73,796,347...73,885,996 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:76,286,433...76,290,507
Ensembl chr 8:77,913,761...77,921,201 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056 		JBrowse link
G HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:97,135,751...97,148,378
Ensembl chr10:100,616,208...100,628,470 		JBrowse link
G KCTD10 potassium channel tetramerization domain containing 10 acts_upstream_of_or_within ISO (PMID:25401743) MGI PMID:25401743 NCBI chr12:107,025,380...107,054,118
Ensembl chr12:110,419,859...110,448,773 		JBrowse link
G LOC100976978 E3 ubiquitin-protein ligase HERC2 acts_upstream_of_or_within ISO (PMID:26355680) MGI PMID:26355680 NCBI chr15:1,590,558...1,800,023
Ensembl chr15:25,536,483...25,746,074 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26355680) MGI
Ensembl		 PMID:26355680 GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MAGEA1 MAGE family member A1 involved_in ISO (PMID:15316101) UniProt PMID:15316101 NCBI chr  X:142,727,982...142,732,563 JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G NEURL1 neuralized E3 ubiquitin protein ligase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:100,093,614...100,192,485 JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15845452) Ensembl
MGI		 PMID:15845452 GO_REF:0000107 NCBI chr14:16,155,331...16,158,588 JBrowse link
G NOTCH4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) MGI PMID:24667410 NCBI chr 6:31,842,233...31,871,412
Ensembl chr 6:32,722,112...32,750,978 		JBrowse link
G NRARP NOTCH regulated ankyrin repeat protein acts_upstream_of_or_within ISO (PMID:19154719)
(PMID:21795391)
(PMID:21998026)
(PMID:12794108)		 MGI PMID:12794108 PMID:19154719 PMID:21795391 PMID:21998026 NCBI chr 9:108,358,959...108,361,586 JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr20:17,983,277...18,019,441
Ensembl chr20:17,962,123...17,994,486 		JBrowse link
G RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ISO RGD PMID:11165380 RGD:633801 NCBI chr17:76,452,440...76,456,462 JBrowse link
G RITA1 RBPJ interacting and tubulin associated 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:110,790,401...110,797,343
Ensembl chr12:114,173,173...114,180,288 		JBrowse link
G SLC35C1 solute carrier family 35 member C1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20837470) Ensembl
MGI		 PMID:20837470 GO_REF:0000107 NCBI chr11:45,758,274...45,766,991
Ensembl chr11:46,250,488...46,259,409 		JBrowse link
G TCIM transcriptional and immune response regulator involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:39,347,441...39,348,795
Ensembl chr 8:36,855,045...36,855,365 		JBrowse link
G TSPAN15 tetraspanin 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:65,919,622...65,976,449
Ensembl chr10:68,450,318...68,507,151 		JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:3,066,554...3,090,285 JBrowse link
negative regulation of Notch signaling pathway involved in somitogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:23072809) UniProt PMID:23072809 NCBI chr 7:2,781,493...2,790,936 JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19620969) Ensembl
MGI		 PMID:19620969 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
positive regulation of Notch signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AAK1 AP2 associated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:69,506,651...69,686,765
Ensembl chr2A:70,638,470...70,804,579 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:32561494) Ensembl
BHF-UCL		 PMID:32561494 GO_REF:0000107 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691 		JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11073877) Ensembl
MGI		 PMID:11073877 GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:116,105,935...116,114,241
Ensembl chr 8:118,855,445...118,865,039 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15574878) Ensembl
MGI		 PMID:15574878 GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471 		JBrowse link
G ENHO energy homeostasis associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25074942) Ensembl
TreeGrafter
MGI		 PMID:25074942 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:34,357,384...34,359,369
Ensembl chr 9:35,167,934...35,168,164 		JBrowse link
G EPN2 epsin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,777,430...31,874,469
Ensembl chr17:36,942,381...37,038,509 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16324690) Ensembl
MGI		 PMID:16324690 GO_REF:0000107 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G GAK cyclin G associated kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:952,474...1,049,612
Ensembl chr 4:883,096...967,473 		JBrowse link
G GATA5 GATA binding protein 5 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr20:60,148,359...60,158,886 JBrowse link
G GDF2 growth differentiation factor 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:32561494) Ensembl
BHF-UCL		 PMID:32561494 GO_REF:0000107 NCBI chr10:46,520,808...46,526,414 JBrowse link
G GSX2 GS homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23042297) Ensembl
MGI		 PMID:23042297 GO_REF:0000107 NCBI chr 4:69,837,643...69,840,101
Ensembl chr 4:76,397,180...76,399,715 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in ISO (PMID:12208538) UniProt PMID:12208538 NCBI chr 1:1,261,260...1,263,128 JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817 		JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:10,582,234...10,618,507
Ensembl chr20:10,582,094...10,618,383 		JBrowse link
G JAG2 jagged canonical Notch ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,785,586...85,812,056
Ensembl chr14:105,569,837...105,585,878 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:15302600 RGD:2292509 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISO (PMID:15574878) MGI PMID:15574878 NCBI chr 7:2,781,493...2,790,936 JBrowse link
G LOC100990608 contactin-6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25074942) Ensembl
MGI		 PMID:25074942 GO_REF:0000107 NCBI chr 3:1,021,854...1,339,952
Ensembl chr 3:1,133,190...1,442,622 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210 		JBrowse link
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15574878) Ensembl
MGI		 PMID:15574878 GO_REF:0000107 NCBI chr22:18,385,664...18,407,056
Ensembl chr22:36,218,403...36,239,804 		JBrowse link
G NEPRO nucleolus and neural progenitor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19906856) Ensembl
TreeGrafter
MGI		 PMID:19906856 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:110,152,415...110,169,736
Ensembl chr 3:117,076,649...117,094,041 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24667410) Ensembl
MGI		 PMID:24667410 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G PDCD10 programmed cell death 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:164,703,909...164,755,085
Ensembl chr 3:172,760,923...172,811,430 		JBrowse link
G POGLUT1 protein O-glucosyltransferase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:116,591,271...116,617,382
Ensembl chr 3:123,503,899...123,529,919 		JBrowse link
G RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15574878) Ensembl
MGI		 PMID:15574878 GO_REF:0000107 NCBI chr17:76,452,440...76,456,462 JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in ISO (PMID:25691540) BHF-UCL PMID:25691540 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308 		JBrowse link
G ROBO2 roundabout guidance receptor 2 involved_in ISO (PMID:25691540) BHF-UCL PMID:25691540 NCBI chr 3:76,013,780...77,764,156
Ensembl chr 3:79,030,223...79,632,309 		JBrowse link
G SLC35C2 solute carrier family 35 member C2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20837470) Ensembl
MGI		 PMID:20837470 GO_REF:0000107 NCBI chr20:42,686,735...42,701,321
Ensembl chr20:43,772,681...43,780,671 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:16631155) MGI PMID:16631155 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22274697) Ensembl
MGI		 PMID:22274697 GO_REF:0000107 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104 		JBrowse link
G TSPAN14 tetraspanin 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:76,854,589...76,922,144
Ensembl chr10:80,464,131...80,521,771 		JBrowse link
G TSPAN5 tetraspanin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:90,872,988...91,052,345
Ensembl chr 4:101,536,950...101,717,228 		JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,061,367...97,186,961
Ensembl chr11:100,552,424...100,681,301 		JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:75,581,794...75,829,748
Ensembl chr10:78,294,867...78,492,475 		JBrowse link
positive regulation of transcription of Notch receptor target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAML1 mastermind like transcriptional coactivator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23160044) Ensembl
TreeGrafter
MGI
InterPro		 PMID:23160044 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:174,886,694...174,931,153
Ensembl chr 5:182,230,351...182,242,296 		JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr11:90,982,013...91,350,289
Ensembl chr11:94,511,873...94,873,977 		JBrowse link
G MAML3 mastermind like transcriptional coactivator 3 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 4:132,082,120...132,518,928
Ensembl chr 4:143,391,606...143,562,699 		JBrowse link
G NOTCH1 notch receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23160044)
(PMID:12794108)		 RGD
MGI
Ensembl		 PMID:12794108 PMID:12853432 PMID:23160044 GO_REF:0000107 RGD:1358543 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G RBM15 RNA binding motif protein 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17283045) Ensembl
MGI		 PMID:17283045 GO_REF:0000107 NCBI chr 1:112,987,871...112,996,054
Ensembl chr 1:127,320,147...127,354,537 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12794108) Ensembl
MGI		 PMID:12794108 GO_REF:0000107 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683 		JBrowse link
regulation of Notch signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:37,562,930...37,717,175
Ensembl chr15:55,873,606...56,027,188 		JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19191219) Ensembl
MGI		 PMID:19191219 GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
G CC2D1A coiled-coil and C2 domain containing 1A NOT|acts_upstream_of_or_within ISO (PMID:26720614) MGI PMID:26720614 NCBI chr19:13,468,650...13,493,308 JBrowse link
G CC2D1B coiled-coil and C2 domain containing 1B NOT|acts_upstream_of_or_within ISO (PMID:26720614) MGI PMID:26720614 NCBI chr 1:51,608,126...51,623,748
Ensembl chr 1:53,218,432...53,231,795 		JBrowse link
G CD46 CD46 molecule involved_in ISO (PMID:23086448) UniProt PMID:23086448 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046 		JBrowse link
G DTX1 deltex E3 ubiquitin ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,661,247...110,702,780
Ensembl chr12:114,046,700...114,085,372 		JBrowse link
G GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:143,604,679...143,702,239
Ensembl chr 7:155,804,409...155,848,176 		JBrowse link
G GAS2 growth arrest specific 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27734842) Ensembl
MGI		 PMID:27734842 GO_REF:0000107 NCBI chr11:22,639,677...22,822,208
Ensembl chr11:22,583,367...22,729,243 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12629177) Ensembl
MGI		 PMID:12629177 GO_REF:0000107 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817 		JBrowse link
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:16385447)
(PMID:28089369)		 UniProt PMID:16385447 PMID:28089369 NCBI chr 7:2,781,493...2,790,936 JBrowse link
G LLGL1 LLGL scribble cell polarity complex component 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:32,770,511...32,789,756
Ensembl chr17:37,966,100...37,985,103 		JBrowse link
G LLGL2 LLGL scribble cell polarity complex component 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:69,474,804...69,524,797
Ensembl chr17:75,025,235...75,075,240 		JBrowse link
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,385,664...18,407,056
Ensembl chr22:36,218,403...36,239,804 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24667410) Ensembl
MGI		 PMID:24667410 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NOTCH4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) MGI PMID:24667410 NCBI chr 6:31,842,233...31,871,412
Ensembl chr 6:32,722,112...32,750,978 		JBrowse link
G POFUT1 protein O-fucosyltransferase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:28,496,987...28,527,817
Ensembl chr20:29,625,481...29,655,722 		JBrowse link
G POGLUT1 protein O-glucosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21490058) Ensembl
MGI		 PMID:21490058 GO_REF:0000107 NCBI chr 3:116,591,271...116,617,382
Ensembl chr 3:123,503,899...123,529,919 		JBrowse link
G POSTN periostin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19723774) Ensembl
MGI		 PMID:19723774 GO_REF:0000107 NCBI chr13:18,779,297...18,815,207
Ensembl chr13:37,368,030...37,407,212 		JBrowse link
G PRAG1 PEAK1 related, kinase-activating pseudokinase 1 involved_in ISO (PMID:25038227) UniProt PMID:25038227 NCBI chr 8:10,824,887...10,896,058 JBrowse link
G RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:76,452,440...76,456,462 JBrowse link
G SYNJ2BP synaptojanin 2 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:50,958,861...51,009,395
Ensembl chr14:69,835,548...69,879,537 		JBrowse link
G TSPAN15 tetraspanin 15 NOT|involved_in ISO (PMID:23091066) UniProt PMID:23091066 NCBI chr10:65,919,622...65,976,449
Ensembl chr10:68,450,318...68,507,151 		JBrowse link
G TSPEAR thrombospondin type laminin G domain and EAR repeats involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,791,051...31,005,330
Ensembl chr21:44,087,591...44,299,041 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      signal transduction 5476
        cell surface receptor signaling pathway 2651
          Notch signaling pathway 183
            Notch receptor processing, ligand-dependent 0
            Notch signaling involved in heart development + 1
            Notch signaling pathway involved in arterial endothelial cell fate commitment 1
            Notch signaling pathway involved in camera-type eye photoreceptor fate commitment 0
            Notch signaling pathway involved in forebrain neuroblast division 0
            Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment 0
            Notch signaling pathway involved in somitogenesis + 1
            negative regulation of Notch signaling pathway + 38
            positive regulation of Notch signaling pathway 43
            positive regulation of transcription of Notch receptor target 6
            regulation of Notch signaling pathway + 92
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        signaling 5975
          signal transduction 5476
            cell surface receptor signaling pathway 2651
              Notch signaling pathway 183
                Notch receptor processing, ligand-dependent 0
                Notch signaling involved in heart development + 1
                Notch signaling pathway involved in arterial endothelial cell fate commitment 1
                Notch signaling pathway involved in camera-type eye photoreceptor fate commitment 0
                Notch signaling pathway involved in forebrain neuroblast division 0
                Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment 0
                Notch signaling pathway involved in somitogenesis + 1
                negative regulation of Notch signaling pathway + 38
                positive regulation of Notch signaling pathway 43
                positive regulation of transcription of Notch receptor target 6
                regulation of Notch signaling pathway + 92
paths to the root