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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of microtubule depolymerization
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Accession:GO:0007026 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
Synonyms:exact_synonym: down regulation of microtubule depolymerization;   downregulation of microtubule depolymerization;   microtubule stabilization;   negative regulation of microtubule disassembly
 narrow_synonym: inhibition of microtubule depolymerization;   microtubule rescue;   negative regulation of microtubule catastrophe



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negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within
IEA
ISS
ISO
IBA
GO_REF:0000107
GO_REF:0000024
(PMID:11166179)
(PMID:17192415)
GO_REF:0000033
(PMID:16525027)
Ensembl
UniProt
RGD
GO_Central
PMID:11166179 PMID:16525027 PMID:17192415 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO
IEA
ISS
(PMID:11912491)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11912491 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Atxn7 ataxin 7 involved_in ISO (PMID:22100762) RGD PMID:22100762 NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106
JBrowse link
G Bbof1 basal body orientation factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:37494937)
GO_REF:0000107
RGD
Ensembl
PMID:37494937 GO_REF:0000107 NCBI chr 6:104,055,246...104,081,036
Ensembl chr 6:104,055,241...104,082,071
JBrowse link
G Bmerb1 bMERB domain containing 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:25099998)
GO_Central
RGD
PMID:25099998 GO_REF:0000033 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575
JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:8,746,176...8,806,067
Ensembl chr 3:8,746,176...8,806,072
JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:47,723,251...47,802,606
Ensembl chr13:47,723,121...47,802,597
JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685
JBrowse link
G Ccdc88c coiled-coil domain containing 88C acts_upstream_of_or_within ISO (PMID:33929515) RGD PMID:33929515 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO
ISS
IEA
(PMID:21215777)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:21215777 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Ckap2 cytoskeleton associated protein 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:16061649)
GO_Central
RGD
PMID:16061649 GO_REF:0000033 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within
ISO UniProtKB:O75122 (PMID:15631994), (PMID:16866869)
(PMID:11290329)
RGD PMID:11290329 PMID:15631994 PMID:16866869 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within IDA
ISO
MGI:3693618 (PMID:11290329), (PMID:17113391) RGD PMID:11290329 PMID:17113391 PMID:11290329 RGD:68300 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 involved_in NAS PMID:11290329 UniProt PMID:11290329 RGD:68300 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
JBrowse link
G Diaph3 diaphanous-related formin 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18458159)
Ensembl
RGD
PMID:18458159 GO_REF:0000107 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (PMID:17196341) RGD PMID:17196341 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISS
ISO
GO_REF:0000024
(PMID:22726441)
UniProt
RGD
PMID:22726441 GO_REF:0000024 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 involved_in ISO
ISS
(PMID:12584248) RGD PMID:12584248 PMID:12584248 RGD:12790645 NCBI chr14:79,955,350...79,961,830
Ensembl chr14:79,950,555...79,961,438
JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12584248)
UniProt
RGD
PMID:12584248 GO_REF:0000024 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881
JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO (PMID:12486003) RGD PMID:12486003 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:19237540)
UniProt
RGD
PMID:19237540 GO_REF:0000024 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650
JBrowse link
G Map1a microtubule-associated protein 1A IDA RGD PMID:11896150 RGD:71122 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map1b microtubule-associated protein 1B IDA RGD PMID:11896150 RGD:71122 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2 microtubule-associated protein 2 involved_in IMP PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map6d1 MAP6 domain containing 1 acts_upstream_of_or_within ISO (PMID:16837464) RGD PMID:16837464 NCBI chr11:80,734,148...80,740,377
Ensembl chr11:80,734,148...80,740,377
JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within ISO MGI:1915291 (PMID:15070402) RGD PMID:15070402 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353
JBrowse link
G Mid1ip1 MID1 interacting protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1100537 (PMID:15070402)
UniProt
RGD
PMID:15070402 GO_REF:0000024 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774
JBrowse link
G Nav3 neuron navigator 3 involved_in ISO (PMID:25678558) RGD PMID:25678558 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO (PMID:21703590) RGD PMID:21703590 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665
JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (PMID:16206169) RGD PMID:16206169 NCBI chr 3:118,390,659...118,396,842
Ensembl chr 3:118,390,575...118,394,531
JBrowse link
G Stmn2 stathmin 2 involved_in ISO
IEA
(PMID:18452648)
GO_REF:0000107
RGD
Ensembl
PMID:18452648 GO_REF:0000107 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:12639963) RGD PMID:12639963 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO (PMID:26414402) RGD PMID:26414402 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Trim54 tripartite motif-containing 54 acts_upstream_of_or_within ISO (PMID:10953002) RGD PMID:10953002 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) RGD PMID:26323690 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
JBrowse link
G Wdr47 WD repeat domain 47 acts_upstream_of_or_within ISO MGI:6102912 (PMID:29078390) RGD PMID:29078390 NCBI chr 2:196,226,757...196,287,739
Ensembl chr 2:196,205,238...196,287,739
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      negative regulation of cellular process 5533
        negative regulation of cellular component organization 805
          negative regulation of supramolecular fiber organization 192
            negative regulation of microtubule depolymerization 38
              negative regulation of astral microtubule depolymerization 0
              negative regulation of axonemal microtubule depolymerization 0
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      cellular component organization or biogenesis 7178
        cellular component organization 6924
          organelle organization 3702
            cytoskeleton organization 1548
              microtubule cytoskeleton organization 683
                microtubule polymerization or depolymerization 146
                  regulation of microtubule polymerization or depolymerization 101
                    negative regulation of microtubule polymerization or depolymerization 51
                      negative regulation of microtubule depolymerization 38
                        negative regulation of astral microtubule depolymerization 0
                        negative regulation of axonemal microtubule depolymerization 0
paths to the root