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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidylinositol-3,4,5-trisphosphate binding
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Accession:GO:0005547 term browser browse the term
Definition:Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
Synonyms:exact_synonym: PIP3 binding


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phosphatidylinositol-3,4,5-trisphosphate binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adap1 ArfGAP with dual PH domains 1 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9748531 GO_REF:0000033, RGD:632412 NCBI chr12:15,323,913...15,376,110
Ensembl chr12:15,324,209...15,380,831 		JBrowse link
G Adap2 ArfGAP with dual PH domains 2 enables ISO
IDA
IBA		 (PMID:14690521)
PMID:12018390
GO_REF:0000033		 RGD
GO_Central		 PMID:14690521 PMID:12018390 GO_REF:0000033, RGD:1299471 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 enables ISO
IEA		 (PMID:19203586)
GO_REF:0000107		 RGD
Ensembl		 PMID:19203586 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Anxa8 annexin A8 enables ISO (PMID:16638567) RGD PMID:16638567 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 enables ISO
IBA		 (PMID:11804589)
GO_REF:0000033		 RGD
GO_Central		 PMID:11804589 GO_REF:0000033 NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184 		JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 enables ISO
IBA		 (PMID:11804589)
GO_REF:0000033		 RGD
GO_Central		 PMID:11804589 GO_REF:0000033 NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154 		JBrowse link
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 enables ISO
IBA		 (PMID:11804589)
GO_REF:0000033		 RGD
GO_Central		 PMID:11804589 GO_REF:0000033 NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555 		JBrowse link
G Arhgap9 Rho GTPase activating protein 9 enables ISO (PMID:17339315) RGD PMID:17339315 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 enables IEA
ISO		 GO_REF:0000107
(PMID:10734117)		 Ensembl
RGD		 PMID:10734117 GO_REF:0000107 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754 		JBrowse link
G Btk Bruton tyrosine kinase enables ISO (PMID:17823121) RGD PMID:17823121 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Commd1 copper metabolism domain containing 1 enables ISO (PMID:18940794) RGD PMID:18940794 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501 		JBrowse link
G Cyth3 cytohesin 3 enables ISO
IEA
ISS		 (PMID:23940353), (PMID:9742223)
GO_REF:0000107
GO_REF:0000024
(PMID:11001876), (PMID:9072969)		 RGD
Ensembl
UniProt		 PMID:9072969 PMID:9742223 PMID:11001876 PMID:23940353 GO_REF:0000024 GO_REF:0000107 NCBI chr12:10,840,137...10,933,792
Ensembl chr12:10,840,157...10,933,812 		JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 enables ISO (PMID:11001876) RGD PMID:11001876 NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423 		JBrowse link
G Dnm1 dynamin 1 enables IEA
ISO		 GO_REF:0000107
(PMID:9765310)		 Ensembl
RGD		 PMID:9765310 GO_REF:0000107 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Fchsd2 FCH and double SH3 domains 2 enables ISO (PMID:29887380) RGD PMID:29887380 NCBI chr 1:155,444,471...155,685,350
Ensembl chr 1:155,444,460...155,685,539 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 enables ISO (PMID:21325030), (PMID:22030399) RGD PMID:21325030 PMID:22030399 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Fundc2 FUN14 domain containing 2 enables ISO (PMID:29786068) RGD PMID:29786068 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345 		JBrowse link
G Gab2 GRB2-associated binding protein 2 enables ISS
ISO		 GO_REF:0000024
(PMID:16456001)		 UniProt
RGD		 PMID:16456001 GO_REF:0000024 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 enables ISO (PMID:22573891) RGD PMID:22573891 NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IDA RGD PMID:22948144 RGD:9686140 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hip1r huntingtin interacting protein 1 related enables ISO (PMID:14732715) RGD PMID:14732715 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IDA RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 enables ISO (PMID:22493426) RGD PMID:22493426 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 enables ISO (PMID:22493426) RGD PMID:22493426 NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279 		JBrowse link
G Irgm immunity-related GTPase M enables ISO (PMID:19620982) RGD PMID:19620982 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Jph2 junctophilin 2 enables ISO
ISS		 (PMID:24001019)
GO_REF:0000024		 RGD
UniProt		 PMID:24001019 GO_REF:0000024 NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904 		JBrowse link
G Kif16b kinesin family member 16B enables ISO (PMID:15882625), (PMID:17641687) RGD PMID:15882625 PMID:17641687 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019 		JBrowse link
G Mapkap1 MAPK associated protein 1 enables ISO
ISS		 (PMID:17303383), (PMID:26293922)
GO_REF:0000024		 RGD
UniProt		 PMID:17303383 PMID:26293922 GO_REF:0000024 NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384 		JBrowse link
G Myo10 myosin X enables ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030 		JBrowse link
G Myo1b myosin Ib enables IDA PMID:20610386 UniProt PMID:20610386 RGD:8554686 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Myo1g myosin IG enables ISO (PMID:23038771) RGD PMID:23038771 NCBI chr14:81,386,701...81,401,843
Ensembl chr14:81,386,701...81,401,843 		JBrowse link
G Npm1 nucleophosmin 1 IPI RGD PMID:15893727 RGD:1600871 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645 		JBrowse link
G Nrgn neurogranin IDA RGD PMID:8995284 RGD:9835428 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516 		JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF enables ISO (PMID:28826662) RGD PMID:28826662 NCBI chr10:43,774,113...43,919,718
Ensembl chr10:43,789,293...43,919,723 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase enables ISO
ISS
IEA		 (PMID:18288188)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18288188 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Pard3 par-3 family cell polarity regulator enables IDA PMID:18082612 UniProt PMID:18082612 RGD:8553352 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 enables ISO
ISS		 (PMID:19203586)
GO_REF:0000024		 RGD
UniProt		 PMID:19203586 GO_REF:0000024 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels enables ISO (PMID:18455988) RGD PMID:18455988 NCBI chr10:51,613,202...51,628,108
Ensembl chr10:51,613,126...51,632,264 		JBrowse link
G Pla2g4e phospholipase A2, group IVE enables ISO (PMID:24413173) RGD PMID:24413173 NCBI chr 3:107,132,540...107,198,609
Ensembl chr 3:107,132,541...107,198,233 		JBrowse link
G Plekhb2 pleckstrin homology domain containing B2 enables ISO (PMID:11001876) RGD PMID:11001876 NCBI chr 9:37,049,580...37,082,231
Ensembl chr 9:37,038,751...37,082,231 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 enables ISO (PMID:23235882) RGD PMID:23235882 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831 		JBrowse link
G Rag2 recombination activating 2 enables ISO (PMID:15964836) RGD PMID:15964836 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066 		JBrowse link
G Rs1 retinoschisin 1 enables ISO (PMID:17325137) RGD PMID:17325137 NCBI chr  X:33,962,440...33,992,203
Ensembl chr  X:33,963,657...33,992,115 		JBrowse link
G Washc2c WASH complex subunit 2C enables ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851 		JBrowse link
G Zfyve1 zinc finger FYVE-type containing 1 enables ISO
IBA		 (PMID:11804589)
GO_REF:0000033		 RGD
GO_Central		 PMID:11804589 GO_REF:0000033 NCBI chr 6:103,184,938...103,234,111
Ensembl chr 6:103,184,938...103,234,039 		JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 enables ISO (PMID:11433298) RGD PMID:11433298 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20807
    binding 17844
      small molecule binding 6267
        ion binding 5988
          anion binding 2605
            phosphatidylinositol-3,4,5-trisphosphate binding 46
Path 2
Term Annotations click to browse term
  molecular_function 20807
    binding 17844
      lipid binding 891
        phospholipid binding 510
          phosphatidylinositol binding 294
            phosphatidylinositol phosphate binding 195
              phosphatidylinositol-3,4,5-trisphosphate binding 46
paths to the root