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ONTOLOGY REPORT - ANNOTATIONS

Term:core promoter sequence-specific DNA binding
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Accession:GO:0001046 term browser browse the term
Definition:Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
Synonyms:narrow_synonym: bacterial-type RNA polymerase core promoter sequence-specific DNA binding;   eubacterial-type RNA polymerase core promoter sequence-specific DNA binding
 related_synonym: core promoter binding
 alt_id: GO:0000985;   GO:0001047


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core promoter sequence-specific DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago1 argonaute RISC component 1 enables ISO (PMID:25336585) RGD PMID:25336585 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 enables IEA
ISO		 GO_REF:0000107
(PMID:25336585)		 Ensembl
RGD		 PMID:25336585 GO_REF:0000107 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Drap1 Dr1 associated protein 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425 		JBrowse link
G Fendrr FOXF1 adjacent non-coding developmental regulatory RNA enables ISO (PMID:23369715) RGD PMID:23369715 NCBI chr19:49,127,225...49,152,780
Ensembl chr19:49,121,214...49,153,240 		JBrowse link
G Foxp1 forkhead box P1 enables ISO (PMID:28218735) RGD PMID:28218735 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Hdac1 histone deacetylase 1 enables ISO (PMID:23629966) RGD PMID:23629966 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Isl1 ISL LIM homeobox 1 IDA RGD PMID:11043578 RGD:8554127 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Jph2 junctophilin 2 enables ISS
ISO		 GO_REF:0000024
(PMID:30409805)		 UniProt
RGD		 PMID:30409805 GO_REF:0000024 NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904 		JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 enables ISO (PMID:15746104) RGD PMID:15746104 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556 		JBrowse link
G Klf10 KLF transcription factor 10 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:20070857)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20070857 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994 		JBrowse link
G Mmp12 matrix metallopeptidase 12 enables IEA
ISO		 GO_REF:0000107
(PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor enables ISO (PMID:30873824) RGD PMID:30873824 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nkx2-1 NK2 homeobox 1 enables IMP PMID:9425125 CAFA PMID:9425125 RGD:12792996 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Npm1 nucleophosmin 1 enables ISO (PMID:19160485) RGD PMID:19160485 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 enables ISO
IEA		 (PMID:17081986)
GO_REF:0000107		 RGD
Ensembl		 PMID:17081986 GO_REF:0000107 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Polr2a RNA polymerase II subunit A enables ISO (PMID:22723415) RGD PMID:22723415 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455 		JBrowse link
G Snapc3 small nuclear RNA activating complex, polypeptide 3 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:97,817,827...97,868,494
Ensembl chr 5:97,817,947...97,844,650 		JBrowse link
G Taf4 TATA-box binding protein associated factor 4 contributes_to ISO (PMID:15601843) RGD PMID:15601843 NCBI chr 3:167,017,992...167,083,413
Ensembl chr 3:167,017,993...167,083,356 		JBrowse link
G Tbp TATA box binding protein enables ISO (PMID:9841876) RGD PMID:9841876 NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016 		JBrowse link
G Tp53 tumor protein p53 enables ISO
IEA		 (PMID:23629966)
GO_REF:0000107		 RGD
Ensembl		 PMID:23629966 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Zbtb17 zinc finger and BTB domain containing 17 enables ISO (PMID:19160485) RGD PMID:19160485 NCBI chr 5:153,753,508...153,774,613
Ensembl chr 5:153,753,569...153,774,609 		JBrowse link
RNA polymerase I core promoter sequence-specific DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz2a bromodomain adjacent to zinc finger domain, 2A contributes_to ISO (PMID:22368283) RGD PMID:22368283 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor enables ISO (PMID:22368283) RGD PMID:22368283 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 contributes_to
enables		 ISO
IEA		 (PMID:22368283)
GO_REF:0000107		 RGD
Ensembl		 PMID:22368283 GO_REF:0000107 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 contributes_to ISO (PMID:22368283) RGD PMID:22368283 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Taf1b TATA-box binding protein associated factor, RNA polymerase I subunit B enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:21921198), (PMID:21921199)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:21921198 PMID:21921199 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:41,116,980...41,194,593
Ensembl chr 6:41,117,420...41,194,593 		JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C enables ISO
IBA		 (PMID:22368283)
GO_REF:0000033		 RGD
GO_Central		 PMID:22368283 GO_REF:0000033 NCBI chr19:47,652,451...47,658,971
Ensembl chr19:47,652,452...47,658,971 		JBrowse link
G Tbp TATA box binding protein enables ISO (PMID:11250903) RGD PMID:11250903 NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016 		JBrowse link
G Ubtf upstream binding transcription factor enables ISO
IBA		 (PMID:22368283)
GO_REF:0000033		 RGD
GO_Central		 PMID:22368283 GO_REF:0000033 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969 		JBrowse link
RNA polymerase II core promoter sequence-specific DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor enables ISO
IEA		 (PMID:27959439)
GO_REF:0000107		 RGD
Ensembl		 PMID:27959439 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta enables IEA
ISO		 GO_REF:0000107
(PMID:25472717)		 Ensembl
RGD		 PMID:25472717 GO_REF:0000107 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Egr1 early growth response 1 IDA RGD PMID:21451041 RGD:5131648 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit enables ISO (PMID:16717091), (PMID:20798045) RGD PMID:16717091 PMID:20798045 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit enables ISO (PMID:10704222) RGD PMID:10704222 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gbx2 gastrulation brain homeobox 2 enables ISO (PMID:23144817) RGD PMID:23144817 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212 		JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 enables ISO (PMID:29111974) RGD PMID:29111974 NCBI chr 6:110,488,891...110,521,502
Ensembl chr 6:110,488,931...110,521,511 		JBrowse link
G Gtf2b general transcription factor IIB enables ISO
IBA
IEA
ISS		 (PMID:10619841), (PMID:16230532), (PMID:7675079), (PMID:9420329)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:7675079 PMID:9420329 PMID:10619841 PMID:16230532 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651 		JBrowse link
G H2az1 H2A.Z variant histone 1 enables ISO (PMID:19633671), (PMID:23637611) RGD PMID:19633671 PMID:23637611 NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485 		JBrowse link
G H3f3a H3.3 histone A enables ISO (PMID:19633671) RGD PMID:19633671 NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908 		JBrowse link
G H3f3b H3.3 histone B enables ISO (PMID:19633671) RGD PMID:19633671 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hdac1 histone deacetylase 1 enables ISO (PMID:19057576) RGD PMID:19057576 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hmga1 high mobility group AT-hook 1 enables ISO (PMID:15713121) RGD PMID:15713121 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Pax6 paired box 6 enables IEA
ISO		 GO_REF:0000107
(PMID:16407227)		 Ensembl
RGD		 PMID:16407227 GO_REF:0000107 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 enables ISO
IEA		 (PMID:10541551)
GO_REF:0000107		 RGD
Ensembl		 PMID:10541551 GO_REF:0000107 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma enables ISO (PMID:25921091) RGD PMID:25921091 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit enables ISO (PMID:21343296) RGD PMID:21343296 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rest RE1-silencing transcription factor enables ISO (PMID:29024663) RGD PMID:29024663 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Rfx7 regulatory factor X, 7 enables ISO (PMID:29967452) RGD PMID:29967452 NCBI chr 8:73,254,051...73,339,209
Ensembl chr 8:73,254,051...73,339,209 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 enables ISO (PMID:23637611) RGD PMID:23637611 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 enables ISO (PMID:23386060), (PMID:28753426) RGD PMID:23386060 PMID:28753426 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 enables ISO (PMID:25412659) RGD PMID:25412659 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Tbp TATA box binding protein enables ISO (PMID:29111974) RGD PMID:29111974 NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016 		JBrowse link
G Tbpl1 TATA-box binding protein like 1 enables ISO (PMID:15767669) RGD PMID:15767669 NCBI chr 1:22,777,892...22,803,305
Ensembl chr 1:22,778,459...22,803,122
Ensembl chr 1:22,778,459...22,803,122 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20626
    binding 17717
      organic cyclic compound binding 6134
        nucleic acid binding 3844
          transcription regulatory region nucleic acid binding 1301
            transcription cis-regulatory region binding 1296
              core promoter sequence-specific DNA binding 50
                RNA polymerase I core promoter sequence-specific DNA binding 8
                RNA polymerase II core promoter sequence-specific DNA binding 24
Path 2
Term Annotations click to browse term
  molecular_function 20626
    binding 17717
      organic cyclic compound binding 6134
        nucleic acid binding 3844
          DNA binding 2276
            double-stranded DNA binding 1452
              sequence-specific double-stranded DNA binding 1359
                transcription cis-regulatory region binding 1296
                  core promoter sequence-specific DNA binding 50
                    RNA polymerase I core promoter sequence-specific DNA binding 8
                    RNA polymerase II core promoter sequence-specific DNA binding 24
paths to the root