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Pathways

EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS


Term:goiter
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Accession:EFO:0004283 term browser browse the term
Definition:Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency ( HYPOTHYROIDISM), or hormone overproduction ( HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic ( GOITER, ENDEMIC). Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.
Synonyms:exact_synonym: Thyromegaly;   goiter (disease);   goitre (disease)
 xref: DOID:12176;   HP:0000853;   ICD10:E04;   ICD9:240.9;   MEDGEN:42270;   MESH:D006042;   MONDO:0005397;   MP:0005355;   MedDRA:10018491;   MedDRA:10018496;   MedDRA:10018497;   NCI:C26785;   SCTID:3716002;   SNOMEDCT:3716002;   UMLS:C0018021



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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          endocrine system disease 0
            thyroid disease 0
              goiter 0
                endemic goiter 0
                lingual goiter 0
                nodular goiter + 0
                nontoxic goiter 0
                substernal goiter 0
                toxic diffuse goiter + 0
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