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Term:irritable bowel syndrome
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Accession:DOID:9778 term browser browse the term
Definition:A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
Synonyms:exact_synonym: IBD;   Irritable Bowel Syndromes;   Irritable Colon;   Mucous Colitides;   Mucous Colitis
 related_synonym: Psychogenic IBS
 primary_id: MESH:D043183;   RDO:0007507
 xref: ICD10CM:K58;   ICD10CM:K58.9;   ICD9CM:564.1;   NCI:C82343
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irritable bowel syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:8655978
G Cldn1 claudin 1 JBrowse link 11 77,815,216 77,830,373 RGD:11344877
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:5130948
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5130948
G Htr3a 5-hydroxytryptamine receptor 3A JBrowse link 8 53,211,436 53,223,878 RGD:6480659
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480673
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:12791275
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11554173
G Mlxipl MLX interacting protein-like JBrowse link 12 24,590,645 24,619,639 RGD:13592920
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:7771566
G Pdia3 protein disulfide isomerase family A, member 3 JBrowse link 3 113,376,983 113,400,707 RGD:9999158
G Rpsa ribosomal protein SA JBrowse link 8 128,806,053 128,809,987 RGD:5686874
G Tpsab1 tryptase alpha/beta 1 JBrowse link 10 14,701,253 14,703,668 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    syndrome 5215
      irritable bowel syndrome 13
Path 2
Term Annotations click to browse term
  disease 15603
    disease of anatomical entity 14934
      gastrointestinal system disease 4392
        Gastrointestinal Diseases 2318
          intestinal disease 1387
            colonic disease 943
              functional colonic disease 13
                irritable bowel syndrome 13
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.