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ONTOLOGY REPORT - ANNOTATIONS
Term:fatty liver disease
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Accession:DOID:9452 term browser browse the term
Definition:Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
Synonyms:exact_synonym: Fatty change of liver;   Liver Steatosis;   Steatohepatitides;   Steatohepatitis;   Steatosis of Liver;   Visceral Steatoses;   fatty liver;   hepatic lipidosis;   hepatosteatosis;   liver steatoses;   visceral steatosis
 primary_id: MESH:D005234
 alt_id: RDO:0001271
 xref: ICD10CM:K70.0;   ICD9CM:571.0
For additional species annotation, visit the Alliance of Genome Resources.

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fatty liver disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:1598534
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:1598602
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:2301064
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:1625727
G Acacb acetyl-CoA carboxylase beta JBrowse link 12 48,127,149 48,238,969 RGD:1625727
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1599139
RGD:5686883
RGD:5686674
G Adk adenosine kinase JBrowse link 15 3,033,535 3,435,888 RGD:13592920
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1559320
G Akp3 alkaline phosphatase 3, intestine, not Mn requiring JBrowse link 9 94,228,960 94,232,001 RGD:14349048
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:1601177
G Angptl4 angiopoietin-like 4 JBrowse link 7 18,627,814 18,634,043 RGD:1625354
RGD:11554173
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:2325770
RGD:11554173
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:13703129
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:11554173
G Atp5if1 ATP synthase inhibitory factor subunit 1 JBrowse link 5 150,719,570 150,723,287 RGD:11554173
G Atp7b ATPase copper transporting beta JBrowse link 16 74,865,516 74,944,935 RGD:11554173
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:11554173
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:11554173
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:5130871
RGD:11554173
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8548844
RGD:11554173
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:14995306
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893500
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:11554173
G Cndp2 carnosine dipeptidase 2 JBrowse link 18 81,521,966 81,539,065 RGD:11554173
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:11554173
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:4144089
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:734818
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:2315513
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:11554173
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:11554173
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:11554173
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:4892244
RGD:11554173
RGD:1626302
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:11554173
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:11554173
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:10400884
G Dhrs7 dehydrogenase/reductase 7 JBrowse link 6 95,522,577 95,541,393 RGD:11554173
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:734934
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:11554173
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:11554173
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1626440
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:11554173
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:12453042
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:11554173
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:14695544
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:7488945
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:14747016
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like JBrowse link 8 122,957,570 122,987,236 RGD:11554173
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:11554173
RGD:14975167
G Gpt2 glutamic--pyruvic transaminase 2 JBrowse link 19 22,599,003 22,633,529 RGD:14975241
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:11554173
G Gpx4 glutathione peroxidase 4 JBrowse link 7 12,516,357 12,519,154 RGD:11554173
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha JBrowse link 6 27,589,840 27,628,921 RGD:1599882
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta JBrowse link 6 27,555,408 27,589,539 RGD:11554173
G Has3 hyaluronan synthase 3 JBrowse link 19 39,063,298 39,077,745 RGD:11554173
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1601460
RGD:1601452
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:11554173
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:11354957
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:13592920
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:2308948
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:4145478
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889416
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1626661
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2307258
RGD:2307264
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:2311137
RGD:11554173
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:2308857
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:2308857
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:14700926
RGD:14701028
RGD:14700935
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6483019
G Keap1 Kelch-like ECH-associated protein 1 JBrowse link 8 22,250,518 22,259,868 RGD:6893372
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:11554173
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:11554173
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:11554173
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:13592920
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:13592920
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:9585751
G Mat1a methionine adenosyltransferase 1A JBrowse link 16 18,690,649 18,709,135 RGD:11554173
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:13592920
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12453042
G Mir10b microRNA 10b JBrowse link 3 61,647,978 61,648,086 RGD:11554173
G Mir134 microRNA 134 JBrowse link 6 133,884,547 133,884,619 RGD:11554173
G Mir139 microRNA 139 JBrowse link 1 166,589,545 166,589,612 RGD:11554173
G Mir148b microRNA 148b JBrowse link 7 144,912,038 144,912,134 RGD:11554173
G Mir150 microRNA 150 JBrowse link 1 101,115,974 101,116,058 RGD:11554173
G Mir154 microRNA 154 JBrowse link 6 133,888,586 133,888,669 RGD:11554173
G Mir17 microRNA 17 JBrowse link 15 100,179,879 100,179,962 RGD:11554173
G Mir183 microRNA 183 JBrowse link 4 57,463,569 57,463,678 RGD:11554173
G Mir219a1 microRNA 219a-1 JBrowse link 20 3,816,158 3,816,267 RGD:11554173
G Mir224 microRNA 224 JBrowse link X 152,223,754 152,223,835 RGD:18182925
G Mir320a microRNA 320a JBrowse link 15 52,134,276 52,134,357 RGD:11554173
G Mir34a microRNA 34a JBrowse link 5 167,092,491 167,092,592 RGD:11554173
G Mir410 microRNA 410 JBrowse link 6 133,893,997 133,894,072 RGD:11554173
G Mir449c microRNA 449c JBrowse link 2 44,896,066 44,896,164 RGD:11554173
G Mir503 microRNA 503 JBrowse link X 158,148,476 158,148,546 RGD:11554173
G Mir542 microRNA 542 JBrowse link X 158,152,146 158,152,224 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:1580580
G Mttp microsomal triglyceride transfer protein JBrowse link 2 243,366,181 243,407,608 RGD:1625483
RGD:11554173
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:11554173
G Neil1 nei-like DNA glycosylase 1 JBrowse link 8 61,817,258 61,824,023 RGD:11554173
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6893372
RGD:11554173
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:5135028
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:5133249
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:11554173
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:11554173
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:11554173
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:11554173
RGD:15045573
RGD:14696795
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:11554173
G Nrep neuronal regeneration related protein JBrowse link 18 26,183,753 26,212,796 RGD:11554173
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:12453042
G Otc ornithine carbamoyltransferase JBrowse link X 13,524,804 13,601,074 RGD:4144061
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:13592920
G Plin2 perilipin 2 JBrowse link 5 104,984,413 105,010,863 RGD:1625752
RGD:11554173
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:11554173
RGD:14981590
RGD:11055420
RGD:14981585
RGD:14981583
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:11554173
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:11554173
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:5509939
RGD:15042851
RGD:11554173
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:11554173
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1580685
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:7241844
RGD:7242179
RGD:7242012
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6484544
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1642523
G Psma5 proteasome 20S subunit alpha 5 JBrowse link 2 211,050,344 211,073,706 RGD:11554173
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2292522
RGD:11554173
RGD:1302555
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135028
G Ptma prothymosin alpha JBrowse link 9 93,545,396 93,549,436 RGD:11554173
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:5135028
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:11554173
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:11554173
G Serpina6 serpin family A member 6 JBrowse link 6 127,523,948 127,534,178 RGD:11554173
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:11554173
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:1642523
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9585751
RGD:11554173
G Sirt7 sirtuin 7 JBrowse link 10 109,796,046 109,802,821 RGD:11554173
G Slc13a5 solute carrier family 13 member 5 JBrowse link 10 58,806,581 58,835,549 RGD:11554173
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:11554173
G Slc27a4 solute carrier family 27 member 4 JBrowse link 3 8,363,937 8,376,858 RGD:1625640
G Slc2a2 solute carrier family 2 member 2 JBrowse link 2 114,413,427 114,445,418 RGD:11554173
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:1598602
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1625677
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:1625677
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:11554173
G Sts steroid sulfatase JBrowse link X 45,420,418 45,428,748 RGD:11554173
G Suox sulfite oxidase JBrowse link 7 3,098,228 3,102,179 RGD:1600114
G Tf transferrin JBrowse link 8 111,694,570 111,721,275 RGD:11554173
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:2306156
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:7204423
RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:14402029
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:11554173
Alcoholic Fatty Liver term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686674
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:1599041
RGD:15036811
RGD:15036805
RGD:14696776
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:14995489
G Ccr2 C-C motif chemokine receptor 2 RGD:14995489
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:14401742
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:11041117
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491781
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:2315516
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:11554173
RGD:14700884
RGD:14700870
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:9588654
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:11041633
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link 10 46,339,821 46,404,640 RGD:1642369
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:11554173
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:11075083
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:2312349
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1625694
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:7207884
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:14697697
RGD:14700554
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:14995434
Congenital Visceral Steatosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adk adenosine kinase JBrowse link 15 3,033,535 3,435,888 RGD:1300259
non-alcoholic fatty liver term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:14995335
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:14747013
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:14975250
G Gpt2 glutamic--pyruvic transaminase 2 JBrowse link 19 22,599,003 22,633,529 RGD:14975250
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:14985251
RGD:14985252
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:15045573
non-alcoholic fatty liver disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11040992
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:11040992
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:11554173
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:11554173
RGD:14700775
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:11040992
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 6 7,935,771 7,961,207 RGD:15045604
RGD:15045610
G Abcg8 ATP binding cassette subfamily G member 8 JBrowse link 6 7,961,413 7,980,708 RGD:15045604
RGD:15045610
G Acadm acyl-CoA dehydrogenase medium chain JBrowse link 2 260,124,418 260,148,589 RGD:10047124
G Acadvl acyl-CoA dehydrogenase, very long chain JBrowse link 10 56,619,321 56,624,468 RGD:10047121
RGD:10047124
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:11541090
G Actb actin, beta JBrowse link 12 13,715,843 13,718,813 RGD:11541097
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 JBrowse link 3 5,519,921 5,558,390 RGD:2315953
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 2 243,702,035 243,720,063 RGD:11554173
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5685373
RGD:14401719
RGD:11076260
RGD:14401717
RGD:11554173
RGD:5686841
RGD:5686810
RGD:5686660
RGD:5686355
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:5684892
G Ahcy adenosylhomocysteinase JBrowse link 3 150,587,833 150,603,057 RGD:11554173
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:11554173
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:11554173
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 JBrowse link 5 61,382,351 61,387,359 RGD:11554173
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:11554173
RGD:15042863
RGD:11536476
RGD:15036808
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 JBrowse link 5 158,090,238 158,115,725 RGD:11554173
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:5509622
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6904141
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link 18 74,156,553 74,164,490 RGD:13703054
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:11554173
G B3gat1 beta-1,3-glucuronyltransferase 1 JBrowse link 8 27,777,024 27,804,368 RGD:11554173
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:11554173
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:14995922
RGD:14995928
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:14995335
G Ccr2 C-C motif chemokine receptor 2 RGD:14995492
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:11554173
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893543
RGD:11041117
G Cideb cell death-inducing DFFA-like effector b JBrowse link 15 34,439,844 34,444,244 RGD:15045610
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:8552713
RGD:2308807
G Cpt1a carnitine palmitoyltransferase 1A JBrowse link 1 218,568,157 218,629,679 RGD:14747028
RGD:11554173
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:11554173
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:11554173
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:11554173
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:11554173
RGD:11573192
RGD:14700881
RGD:14700871
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 JBrowse link 8 130,548,418 130,550,388 RGD:15045610
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:10400900
RGD:10401056
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 JBrowse link 12 12,749,026 12,782,078 RGD:11554173
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:9588320
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:11554173
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:11554173
G Folr2 folate receptor beta JBrowse link 1 166,915,045 166,933,377 RGD:11554173
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:14401598
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:14695535
RGD:14695545
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449177
G Gnmt glycine N-methyltransferase JBrowse link 9 16,565,274 16,568,626 RGD:11554173
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:14975160
RGD:14975251
G Gpt2 glutamic--pyruvic transaminase 2 JBrowse link 19 22,599,003 22,633,529 RGD:14975251
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:11352823
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401873
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:11554173
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:11554173
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:11554173
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha JBrowse link 6 27,589,840 27,628,921 RGD:14694831
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:15042878
RGD:15042880
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:8694420
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:5508690
RGD:15045610
RGD:15045604
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:9491781
G Ide insulin degrading enzyme JBrowse link 1 255,914,465 256,014,168 RGD:13792804
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:12904726
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:12904726
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:14975151
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145478
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655964
RGD:14696674
RGD:14696664
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:14975293
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:14401582
G Il3 interleukin 3 JBrowse link 10 39,620,535 39,622,973 RGD:11554173
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:7829808
RGD:14975293
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:14700929
RGD:14700932
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:6483014
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:6483014
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6483030
RGD:11554173
G Klb klotho beta JBrowse link 14 44,529,523 44,614,093 RGD:11554173
G Lama1 laminin subunit alpha 1 JBrowse link 9 115,916,907 116,042,123 RGD:11554173
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:11554173
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:2311137
RGD:11554173
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:14696694
RGD:13592920
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:11554173
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:13793398
RGD:13794377
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:13506784
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:14694829
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:13204743
G Mir200b microRNA 200b JBrowse link 5 173,490,144 173,490,238 RGD:14928332
RGD:14974031
G Mir34a microRNA 34a JBrowse link 5 167,092,491 167,092,592 RGD:11533145
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:14696706
RGD:14696748
G Mttp microsomal triglyceride transfer protein JBrowse link 2 243,366,181 243,407,608 RGD:1581245
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:10412712
RGD:11554173
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:13592920
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:5509578
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:13434914
RGD:11554173
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:15045610
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:11554173
RGD:15090799
RGD:15045610
RGD:15045604
RGD:14701033
RGD:14696797
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 JBrowse link 13 53,750,470 53,870,288 RGD:11554173
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:11554173
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link 10 46,339,821 46,404,640 RGD:11554173
G Pgrmc1 progesterone receptor membrane component 1 JBrowse link X 123,205,869 123,213,880 RGD:13592920
G Phyh phytanoyl-CoA 2-hydroxylase JBrowse link 17 77,287,580 77,304,482 RGD:13831310
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:6482771
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:11554173
RGD:8554872
RGD:14981596
RGD:14981593
RGD:13463463
G Pon2 paraoxonase 2 JBrowse link 4 30,344,705 30,380,119 RGD:8661257
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:11554173
RGD:14747028
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:11554173
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6484527
RGD:7241847
G Prf1 perforin 1 JBrowse link 20 30,915,294 30,920,804 RGD:11554173
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:11554173
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:11554173
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:11554173
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:11554173
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11086779
G Rag2 recombination activating 2 JBrowse link 3 91,191,837 91,200,134 RGD:11554173
G Rarres2 retinoic acid receptor responder 2 JBrowse link 4 78,205,809 78,208,956 RGD:15036822
G Rdx radixin JBrowse link 8 56,570,728 56,612,851 RGD:11554173
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:7207249
G Samm50 SAMM50 sorting and assembly machinery component JBrowse link 7 125,058,966 125,082,506 RGD:13463463
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:11554173
G Serpinb2 serpin family B member 2 JBrowse link 13 27,449,907 27,463,015 RGD:11554173
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208545
G Sidt2 SID1 transmembrane family, member 2 JBrowse link 8 50,230,335 50,246,979 RGD:13592920
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9585663
RGD:11554173
RGD:9586021
RGD:9585746
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:9586049
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:9586049
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:9586052
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:6484527
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1581245
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6483030
G Stc2 stanniocalcin 2 JBrowse link 10 16,542,909 16,552,675 RGD:11554173
G Tff3 trefoil factor 3 JBrowse link 20 9,850,800 9,855,481 RGD:14747028
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:11541090
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:11554173
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7777122
RGD:14700658
RGD:14700656
G Tm6sf2 transmembrane 6 superfamily member 2 JBrowse link 16 21,092,483 21,099,695 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10450574
RGD:14995482
RGD:14975151
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:11554173
G Trib3 tribbles pseudokinase 3 JBrowse link 3 147,814,056 147,819,650 RGD:11554173
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:7175312
RGD:7204435
RGD:7204434
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:14401753
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:11554173
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:11554173
non-alcoholic steatohepatitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:14975280
RGD:14995462
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:14995335
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:15045601
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:15045601
RGD:15092090
G Gpbar1 G protein-coupled bile acid receptor 1 JBrowse link 9 81,555,914 81,560,931 RGD:15092090
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:14975143
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:14975143
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:15092090
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:15045601
RGD:15092090
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:15092090
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:15092090
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:15090806
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:15090806
Reye syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:14694843
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:13592920
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15553
    disease of anatomical entity 14837
      endocrine system disease 4808
        liver disease 2334
          fatty liver disease 265
            Acute Fatty Liver of Pregnancy 0
            Alcoholic Fatty Liver 20
            Congenital Visceral Steatosis 1
            Lipoatrophy with Diabetes, Hepatic Steatosis, Cardiomyopathy, and Leukomelanodermic Papules 0
            Reye syndrome 2
            non-alcoholic fatty liver disease + 161
Path 2
Term Annotations click to browse term
  disease 15553
    Developmental Diseases 8823
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 7613
        genetic disease 7096
          inherited metabolic disorder 1884
            lipid metabolism disorder 741
              lipid storage disease 364
                fatty liver disease 265
                  Acute Fatty Liver of Pregnancy 0
                  Alcoholic Fatty Liver 20
                  Congenital Visceral Steatosis 1
                  Lipoatrophy with Diabetes, Hepatic Steatosis, Cardiomyopathy, and Leukomelanodermic Papules 0
                  Reye syndrome 2
                  non-alcoholic fatty liver disease + 161
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.