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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:type 2 diabetes mellitus
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Accession:DOID:9352 term browser browse the term
Definition:A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. (DO)
Synonyms:exact_synonym: Diabetes Mellitus, Type II;   Diabetes mellitus with hyperinsulinemia;   Diabetes mellitus, noninsulin-dependent, late-onset;   Ketosis-Resistant Diabetes Mellitus;   Maturity Onset Diabetes Mellitus;   Maturity-Onset Diabetes;   NIDDM;   Non-Insulin-Dependent Diabetes Mellitus;   Noninsulin-Dependent Diabetes Mellitus;   T2D;   adult-onset diabetes mellitus;   insulin-resistant diabetes mellitus;   slow-onset diabetes mellitus;   stable diabetes mellitus;   type 2 diabetes
 narrow_synonym: DIABETES MELLITUS, NONINSULIN-DEPENDENT, MATERNALLY TRANSMITTED;   DIABETES MELLITUS, NONINSULIN-DEPENDENT, WITH ACANTHOSIS NIGRICANS AND HYPERTENSION;   DIABETES MELLITUS, TYPE II, DIGENIC;   INSULIN RESISTANCE, SEVERE, DIGENIC
 related_synonym: DIABETES MELLITUS TYPE 2, SUSCEPTIBILITY TO;   DIABETES MELLITUS, TYPE II, SUSCEPTIBILITY TO;   HYPERTENSION, INSULIN RESISTANCE-RELATED, SUSCEPTIBILITY TO;   MATURITY-ONSET DIABETES INSULIN RESISTANCE, SUSCEPTIBILITY TO;   NEUROD1-RELATED CONDITION;   UCP3 polymorphism G/A;   diabetes mellitus type 2, protection against;   noninsulin-dependent diabetes mellitus, association with
 primary_id: MESH:D003924
 alt_id: MIM:125853
 xref: EFO:0001360;   EFO:0010164;   ICD10CM:E11;   MONDO:0005148;   NCI:C26747


show annotations for term's descendants           Sort by:
type 2 diabetes mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AANAT aralkylamine N-acetyltransferase ISO mRNA, protein:increased expression, decreased activity:pineal gland RGD PMID:16441550 RGD:2301037 NCBI chr17:76,453,351...76,470,117
Ensembl chr17:76,453,351...76,470,117 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 onset IAGP DNA:SNP:exon:p.R230C (rs9282541) (human) RGD PMID:18003760 RGD:2312576 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 IAGP DNA:polymorphism:exon (human) RGD PMID:19470683 RGD:2312331 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO mRNA: decreased expression: liver
protein: increased expression
mRNA:decreased expression:liver		 RGD PMID:15319330 PMID:18189363 PMID:25152023 RGD:2312736, RGD:2312726, RGD:14700811 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 susceptibility IAGP
EXP		 DNA:missense mutation::A1369S
DNA:polymorphism: :p.S1369A (human)
DNA:polymorphism:exon:
DNA:missense mutations: :p.R248Q, p.K1521N, p.Y356C (human)
DNA:polymorphism:intron:IVS16-3T>C (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset | ClinVar Annotator: match by term: Type 2 diabetes mellitus | ClinVar Annotator: match by term: Type II diabetes mellitus		 ClinVar
OMIM
CTD
RGD		 PMID:1021286 PMID:3202066 PMID:7716548 PMID:8650576 PMID:8751851 More... RGD:2313628, RGD:1598640, RGD:2301898, RGD:737749, RGD:2301901, RGD:2301897 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) ISO mRNA:decreased expression:liver RGD PMID:25152023 RGD:14700811 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ACADS acyl-CoA dehydrogenase short chain IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:18523805 PMID:25741868 PMID:28492532 NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008 		JBrowse link
G ACE angiotensin I converting enzyme susceptibility IEA
IAGP		 DNA:deletion:intron:IVS16+1464-1751del (human) GAD
RGD		 PMID:15118671 PMID:24452036 RGD:1331525, RGD:8142353 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACOT2 acyl-CoA thioesterase 2 ISO RGD PMID:16979414 RGD:1625728 NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658 		JBrowse link
G ACP1 acid phosphatase 1 IAGP RGD PMID:15281007 RGD:2313183 NCBI chr 2:264,947...278,283
Ensembl chr 2:264,140...278,283 		JBrowse link
G ACP7 acid phosphatase 7, tartrate resistant (putative) IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,083,788...39,111,493
Ensembl chr19:39,083,913...39,111,493 		JBrowse link
G ACTN4 actinin alpha 4 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589 		JBrowse link
G ADA adenosine deaminase IEP protein:increased expression:serum RGD PMID:15168879 RGD:2313539 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 IDA protein:increased activity:skeletal muscle tissue
protein:increased activity:artery smooth muscle		 RGD PMID:19633828 PMID:19581416 RGD:2312470, RGD:2313250 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18372903 PMID:23967108 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADCY5 adenylate cyclase 5 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20081858 PMID:23202124 PMID:12607610 RGD:13464136 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing IDA
ISO
IEP
IAGP
EXP		 protein:decreased expression:plasma, myocardium:
associated with myocardial infarction;protein:decreased expression: :
DNA:SNP: :g.45T>G (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12114044 PMID:12354786 PMID:15734870 PMID:19622782 PMID:19708766 More... RGD:2313238, RGD:2313230, RGD:5686359, RGD:5686752, RGD:5686807, RGD:8694412, RGD:14975146 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADIPOR2 adiponectin receptor 2 no_association IAGP
IDA		 Allele A of +33371 A/G polymorphism for ADIPOR2 confers increased risk of T2DM in a Chinese population
Reduced expression of ADIPOR2 mRNA in muscle, which may contribute to insulin resistance
Russian population, 129 cases, 117 controls
985 T2DM cases and 1050 controls, Chinese population, SNP association study		 RGD PMID:18075289 PMID:18363889 PMID:18548168 PMID:19631916 RGD:2312490, RGD:2312486, RGD:2312480, RGD:2312476 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674 		JBrowse link
G ADM adrenomedullin IEP protein:increased expression:plasma RGD PMID:17557032 RGD:2313313 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADRA2A adrenoceptor alpha 2A susceptibility IAGP
ISO		 DNA:SNP:3' utr:rs553668 (human)
mRNA, protein:increased expression:pancreatic islet 		RGD PMID:19965390 PMID:19965390 RGD:2316628, RGD:2316628 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G ADRA2B adrenoceptor alpha 2B onset IAGP DNA:polymorphism (human) RGD PMID:17039423 PMID:17277585 RGD:2313544, RGD:2313543 NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571 		JBrowse link
G ADRB2 adrenoceptor beta 2 no_association IAGP
IEA		 DNA:polymorphisms: :p.R16G, p.Q27E RGD
GAD		 PMID:17221209 PMID:15118671 RGD:1601119, RGD:1331525 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 onset
susceptibility
no_association		 IAGP DNA:missense mutation: :p.I62M (human)
DNA:polymorphism: :p.W64R (human)
DNA:missense mutation:cds:p.W64R rs4994 (human)		 RGD PMID:16444766 PMID:17727676 PMID:19659999 RGD:2313163, RGD:2313149, RGD:2313148 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO RGD PMID:20068140 RGD:13838849 NCBI chr12:57,723,761...57,742,161
Ensembl chr12:57,723,761...57,742,157 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
no_association		 ISO
IAGP		 protein:increased expression:jejunum, intestinal villi (rat)
DNA:SNPs:promoter:-374T>A, -429T/C (human)
DNA:polymorphisms, deletion:promoter, :-374T>A, -429T>C (human)
DNA:SNP: :2245A>G (human)
DNA:SNP: :1704G>T, 2184A>G (human)
DNA:SNP: :557G>A (rs2070600, p.G82S) (human)		 RGD PMID:23630304 PMID:19735169 PMID:23403079 PMID:22154374 PMID:15896660 More... RGD:7243184, RGD:7244245, RGD:7244262, RGD:8695962, RGD:8695969, RGD:8695991, RGD:8695991, RGD:8548676 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGRP agouti related neuropeptide IAGP
ISO		 DNA:polymorphism:promoter:-38C>T (human)
mRNA:decreased expression:hypothalamus		 RGD PMID:11554767 PMID:18001323 RGD:2314000, RGD:2311538 NCBI chr16:67,482,571...67,483,547
Ensembl chr16:67,482,571...67,483,547 		JBrowse link
G AGT angiotensinogen no_association IEP
IAGP		 mRNA, protein:increased expression:smooth muscle cell, carotid artery
DNA:polymorphism: :p.T174M, p.M235T (human)		 RGD PMID:17170378 PMID:9258285 RGD:1601138, RGD:8548863 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:aorta RGD PMID:18463192 RGD:2313550 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AHI1 Abelson helper integration site 1 IEP mRNA:increased expression:vastus lateralis RGD PMID:20045148 RGD:11537398 NCBI chr 6:135,283,532...135,497,740
Ensembl chr 6:135,283,407...135,498,434 		JBrowse link
G AHSG alpha 2-HS glycoprotein susceptibility IAGP
IEP		 DNA:polymorphism: :-469T>G (rs2077119) (human) RGD PMID:18316360 PMID:18633113 RGD:2313812, RGD:2313811 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318 		JBrowse link
G AK1 adenylate kinase 1 ISO protein:increased expression:gastrocnemius muscle (rat) RGD PMID:20127051 RGD:5134362 NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B susceptibility IAGP DNA:repeat, snp:promoter:g.(AC)n, g.-106C>T (human) RGD PMID:15569136 RGD:8548678 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 treatment ISO
EXP		 protein:increased serine phosphorylation:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:31626838 PMID:19289493 PMID:19052261 PMID:24735788 RGD:2311130, RGD:2313556, RGD:39128151 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 IDA
IEP
ISO
IAGP
EXP
ISS		 protein:decreased activity, phosphorylation:vastus lateralis (human)
DNA:missense mutation:cds:p.R274H (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 ClinVar
OMIM
CTD
MouseDO
RGD		 PMID:9536098 PMID:15166380 PMID:16722806 PMID:17327441 PMID:17576681 More... RGD:2307342, RGD:2313405, RGD:2311130, RGD:2313408, RGD:734545 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member IAGP RGD PMID:15563966 RGD:2311149 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO
IAGP		 mRNA:decreased expression:soleus (rat)
DNA:SNP:intron: (human)		 RGD PMID:19106228 PMID:12646233 RGD:2313414, RGD:2313434 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664 		JBrowse link
G ALMS1 ALMS1 centrosome and basal body associated protein no_association IAGP DNA:SNPs: :rs1320374, rs1881245, rs3820700 (human) RGD PMID:16601972 RGD:8696017 NCBI chr 2:73,385,758...73,609,919
Ensembl chr 2:73,385,758...73,625,166 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type IEP protein:decreased activity:platelet (human) RGD PMID:9500559 RGD:2313877 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754 		JBrowse link
G ANGPT2 angiopoietin 2 IEP protein:increased expression:plasma RGD PMID:15823283 RGD:2313815 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G ANGPTL3 angiopoietin like 3 ISO protein:increased expression:liver RGD PMID:15094378 RGD:2314234 NCBI chr 1:62,597,520...62,606,313
Ensembl chr 1:62,597,520...62,606,313 		JBrowse link
G ANKRD23 ankyrin repeat domain 23 ISO RNA:altered expression:heart, brown adipose tissue, skeletal muscle tissue RGD PMID:12456686 RGD:2314859 NCBI chr 2:96,837,912...96,844,021
Ensembl chr 2:96,824,526...96,857,934 		JBrowse link
G AOC3 amine oxidase copper containing 3 ISO
IEP		 protein:increased expression:serum RGD PMID:12663473 PMID:14656718 PMID:19336232 RGD:2313823, RGD:2313822, RGD:2313820 NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130 		JBrowse link
G AP3S2 adaptor related protein complex 3 subunit sigma 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21874001 NCBI chr15:89,830,599...89,893,994
Ensembl chr15:89,830,599...89,894,638 		JBrowse link
G APLN apelin IEP protein:decreased expression:plasma RGD PMID:18484561 RGD:2313944 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956 		JBrowse link
G APLNR apelin receptor ISO protein:decreased expression:renal artery RGD PMID:17692936 RGD:2313945 NCBI chr11:57,233,591...57,237,250
Ensembl chr11:57,233,577...57,237,250 		JBrowse link
G APOA1 apolipoprotein A1 IEP protein:altered localization:plasma lipoprotein particle
protein:increased expression, increased glycation:plasma		 RGD PMID:9649952 PMID:18079481 RGD:2313961, RGD:7241576 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 IEP protein:altered localization:plasma lipoprotein particle
protein:decreased expression:serum		 RGD PMID:9649952 PMID:19817643 RGD:2313961, RGD:2313955 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOA5 apolipoprotein A5 no_association IAGP
IEP		 DNA:polymorphism: :-1131T>C (human)
DNA:polymorphism: :c.553G>T (human)		 RGD PMID:17548321 PMID:16039297 PMID:17087641 RGD:2313318, RGD:2313321, RGD:2313319 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420 		JBrowse link
G APOB apolipoprotein B treatment IEP
IDA		 RGD PMID:18945923 PMID:15161783 RGD:2313981, RGD:11354945 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOC1 apolipoprotein C1 IEP protein:decreased expression:plasma RGD PMID:3757210 RGD:2313953 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC2 apolipoprotein C2 IEP protein:increased expression:plasma RGD PMID:12733353 PMID:3757210 RGD:2313966, RGD:2313953 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G APOD apolipoprotein D IEP
IAGP		 DNA:polymorphism RGD PMID:15369805 PMID:7895459 RGD:2311177, RGD:2311178 NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033 		JBrowse link
G APOE apolipoprotein E IEP
IEA		 protein:increased expression:pancreatic islet RGD
GAD		 PMID:18950899 PMID:15118671 RGD:2317556, RGD:1331525 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APOH apolipoprotein H IEP RGD PMID:16126948 RGD:2313984 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525 		JBrowse link
G APOM apolipoprotein M susceptibility IAGP DNA:SNP:promoter:g.-778T>C(rs805296)(human) RGD PMID:16572495 RGD:2314248 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210 		JBrowse link
G AQP7 aquaporin 7 IEP protein:increased expression:skeletal muscle: RGD PMID:29783856 RGD:13782361 NCBI chr 9:33,383,191...33,402,568
Ensembl chr 9:33,383,179...33,402,682 		JBrowse link
G AR androgen receptor ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator IEP mRNA:decreased expression:pancreatic islet RGD PMID:16096055 RGD:2313995 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ARRB2 arrestin beta 2 treatment ISO RGD PMID:24337852 RGD:13506901 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ARX aristaless related homeobox ISO RGD PMID:16772326 RGD:1599258 NCBI chr  X:25,003,694...25,015,965
Ensembl chr  X:25,003,694...25,016,420 		JBrowse link
G ASIP agouti signaling protein IEP
ISO
ISS		 mRNA:increased expression:adipose tissue
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
MouseDO
RGD		 PMID:8146154 PMID:14633851 RGD:2313999 NCBI chr20:34,186,493...34,269,344
Ensembl chr20:34,194,569...34,269,344 		JBrowse link
G ASL argininosuccinate lyase IEP mRNA:increased expression:leukocyte RGD PMID:16121806 RGD:2314010 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697 		JBrowse link
G ATF3 activating transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:22009485 RGD:6771327 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO
EXP		 mRNA:decreased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16123366 PMID:21216827 PMID:22009485 PMID:27222135 RGD:6892953, RGD:6771327, RGD:13782085 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,870...3,964,464 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta ISO protein:decreased expression:islet of Langerhans (rat) RGD PMID:21117707 RGD:13792619 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984 		JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr 7:69,598,475...70,793,506
Ensembl chr 7:69,598,296...70,793,506 		JBrowse link
G AVP arginine vasopressin ISO protein:increased expression:hypothalamus RGD PMID:17940875 RGD:2301922 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724 		JBrowse link
G AXL AXL receptor tyrosine kinase IMP RGD PMID:10528229 RGD:2325834 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766 		JBrowse link
G B2M beta-2-microglobulin IEP protein:increased expression:serum RGD PMID:15127324 RGD:2311236 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BACE2 beta-secretase 2 treatment ISO RGD PMID:28337562 RGD:13782177 NCBI chr21:41,168,160...41,282,530
Ensembl chr21:41,167,801...41,282,530 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO RGD PMID:23032698 RGD:10053698 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:31626838 PMID:22543177 RGD:10054139 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCHE butyrylcholinesterase susceptibility IAGP
IEA
IDA		 DNA:polymorphism: :p.A539T (human) RGD
GAD		 PMID:11793025 PMID:15118671 PMID:16442234 RGD:2306782, RGD:1331525, RGD:2306780 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16959961 PMID:31626838 PMID:23032698 RGD:10053698 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16959961 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L11 BCL2 like 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G BDNF brain derived neurotrophic factor IEP protein:decreased expression:plasma RGD PMID:17151862 RGD:10059350 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BECN1 beclin 1 treatment ISO RGD PMID:21820301 RGD:11561956 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEP protein:decreased expression:serum: RGD PMID:15747054 RGD:7207410 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23665415 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288 		JBrowse link
G BMAL2 basic helix-loop-helix ARNT like 2 IAGP DNA:SNPs: :rs7950226, rs11022775(human) RGD PMID:17728404 RGD:2314371 NCBI chr12:27,332,836...27,425,286
Ensembl chr12:27,332,836...27,425,289 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin no_association ISO RGD PMID:12584444 RGD:1600600 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845 		JBrowse link
G BTC betacellulin susceptibility IAGP DNA:polymorphism:exon:p.C7G (human)
DNA:polymorphism:promoter:-226A/G (human)		 RGD PMID:15793259 PMID:16306376 RGD:2306973, RGD:2306967 NCBI chr 4:74,744,759...74,794,523
Ensembl chr 4:74,744,759...74,794,523 		JBrowse link
G C10orf67 chromosome 10 open reading frame 67 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar NCBI chr10:23,201,916...23,344,797
Ensembl chr10:23,202,696...23,344,845 		JBrowse link
G C12orf43 chromosome 12 open reading frame 43 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:25057215 NCBI chr12:121,000,486...121,016,487
Ensembl chr12:121,000,486...121,016,502 		JBrowse link
G C19orf47 chromosome 19 open reading frame 47 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:40,292,954...40,348,527
Ensembl chr19:40,319,536...40,348,527 		JBrowse link
G C2CD4A C2 calcium dependent domain containing 4A EXP CTD Direct Evidence: marker/mechanism CTD PMID:20818381 NCBI chr15:62,066,977...62,070,917
Ensembl chr15:62,066,977...62,070,917 		JBrowse link
G C2CD4B C2 calcium dependent domain containing 4B EXP CTD Direct Evidence: marker/mechanism CTD PMID:20818381 NCBI chr15:62,163,535...62,165,285
Ensembl chr15:62,163,535...62,165,285 		JBrowse link
G C3 complement C3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20504758 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D susceptibility IAGP
IEP		 DNA:SNPs: :rs9841978,rs312486(human)
mRNA:decreased expression:pancreatic islet:		 RGD PMID:23229155 PMID:23229155 RGD:13506727, RGD:13506727 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733 		JBrowse link
G CADM2 cell adhesion molecule 2 IAGP DNA:SNP: :rs13078807 (human) RGD PMID:28401323 RGD:15092076 NCBI chr 3:84,958,989...86,074,429
Ensembl chr 3:84,958,989...86,074,429 		JBrowse link
G CALCA calcitonin related polypeptide alpha ISO protein:decreased expression:dorsal root ganglion, neuron RGD PMID:17151309 PMID:19816194 RGD:2314035, RGD:2314032 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CALM1 calmodulin 1 ISO mRNA:decreased expression:heart RGD PMID:21216827 RGD:6892953 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268 		JBrowse link
G CAPN10 calpain 10 IEP
ISO
IAGP
EXP		 mRNA:increased expression:pancreas
DNA:SNP
mRNA:decreased expression
DNA:polymorphism
associated with Hypertension;DNA:SNPs:intron:rs3792267, rs2975760 (human)
DNA:SNP:intron:rs2975760 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23349674 PMID:19688040 PMID:14658759 PMID:14646187 PMID:16721485 More... RGD:4107074, RGD:737693, RGD:1625063, RGD:1625049, RGD:7247733, RGD:7247734, RGD:7247735 NCBI chr 2:240,586,734...240,599,104
Ensembl chr 2:240,586,734...240,617,705 		JBrowse link
G CAPN12 calpain 12 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,730,192...38,744,693
Ensembl chr19:38,730,187...38,769,904 		JBrowse link
G CARTPT CART prepropeptide ISO protein:increased expression:pancreatic B cell RGD PMID:16443761 RGD:2313632 NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) ISO RGD PMID:23032698 RGD:10053698 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP3 caspase 3 IEP
EXP		 protein:increased activity:pancreatic B cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15531508 PMID:19100955 RGD:2311446 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:23032698 RGD:10053698 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15531508 PMID:17563067 RGD:2311429 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 IAGP DNA:SNP (human) RGD PMID:16038259 RGD:2311246 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CASQ1 calsequestrin 1 no_association IAGP DNA:SNPs: :multiple
DNA:SNP: :rs2275703(human)
DNA:SNP: :rs617698(human)		 RGD PMID:15561963 PMID:17681849 PMID:15561962 PMID:18269685 RGD:2314135, RGD:2314134, RGD:2314136, RGD:2314133 NCBI chr 1:160,190,575...160,201,886
Ensembl chr 1:160,190,575...160,201,886 		JBrowse link
G CAT catalase IEP
EXP		 protein:decreased activity:plasma:
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:15111504 PMID:15531508 PMID:12357295 RGD:9068922 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBS cystathionine beta-synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23665415 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CCDC92 coiled-coil domain containing 92 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:123,935,626...123,972,831
Ensembl chr12:123,918,660...123,972,831 		JBrowse link
G CCKAR cholecystokinin A receptor ISO DNA:deletion RGD PMID:16815799 RGD:1625200 NCBI chr 4:26,481,396...26,490,484
Ensembl chr 4:26,481,396...26,490,484 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO protein:increased expression:urine RGD PMID:18388116 PMID:25899686 RGD:2301862, RGD:14995493 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEP protein:increased expression:serum RGD PMID:17966842 RGD:2307064 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN2 cellular communication network factor 2 ISO mRNA, protein:increased expression:left ventricle (rat) RGD PMID:19902320 RGD:2314357 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCND2 cyclin D2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24464100 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CCNP cyclin P IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:40,222,208...40,226,689
Ensembl chr19:40,222,208...40,226,697 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 IEP protein:increased expression:monocyte RGD PMID:16631114 RGD:2313561 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 treatment IEP
ISO		 protein:increased expression:monocyte RGD PMID:17966842 PMID:23063706 RGD:2307064, RGD:8552229 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) severity ISO
IAGP
IEP
IDA
EXP		 protein:increased expression:aorta
DNA:nonsense mutation: :p.L360X
DNA:SNP:promoter, rs1527479 (human)
protein:increased expression:plasma
protein:increased expression:heart
protein:increased expression:platelet
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 CTD
ClinVar
RGD		 PMID:16911630 PMID:16952981 PMID:25741868 PMID:31626838 PMID:32347024 More... RGD:2307211, RGD:2307218, RGD:2307213, RGD:2307212, RGD:2307219, RGD:6893499, RGD:11040908 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD38 CD38 molecule ISO
IAGP
IDA		 mRNA:decreased expression:pancreatic islet
DNA:missense mutation: :p.R140W (human)		 RGD PMID:7669044 PMID:9754820 PMID:12242463 RGD:2307234, RGD:2307233, RGD:2307232 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232 		JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:serum
associated with non-alcoholic steatohepatitis;mRNA:increased expression:visceral abdominal adipose tissue		 RGD PMID:16423632 PMID:19280268 RGD:2314214, RGD:5688143 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CDK4 cyclin dependent kinase 4 no_association IMP
IAGP		 DNA:polymorphism:intron:IVS4-40G>A (human) RGD PMID:18678431 PMID:19695727 RGD:2314611, RGD:2314610 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 IAGP
EXP
ISS		 DNA:snps: :multiple
DNA:snp: :rs7754840(human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 ClinVar
CTD
MouseDO
RGD		 PMID:17460697 PMID:17463246 PMID:17463248 PMID:17463249 PMID:23104008 More... RGD:2313949, RGD:2313941, RGD:2313947 NCBI chr 6:20,534,457...21,232,404
Ensembl chr 6:20,534,457...21,232,404 		JBrowse link
G CDO1 cysteine dioxygenase type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23665415 NCBI chr 5:115,804,733...115,816,659
Ensembl chr 5:115,804,733...115,816,659 		JBrowse link
G CEL carboxyl ester lipase IAGP DNA:deletion:exon
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar
RGD		 PMID:25741868 PMID:16369531 RGD:2313964 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861 		JBrowse link
G CHI3L1 chitinase 3 like 1 IEP protein:increased secretion:plasma (human) RGD PMID:21143859 RGD:4892628 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CISD2 CDGSH iron sulfur domain 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 4:102,868,992...102,892,807
Ensembl chr 4:102,868,974...102,892,807 		JBrowse link
G CLC Charcot-Leyden crystal galectin IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,731,255...39,738,029
Ensembl chr19:39,731,255...39,738,029 		JBrowse link
G CLPS colipase susceptibility IAGP DNA:polymorphism:exon:p.R109C (human) RGD PMID:16189801 RGD:2314627 NCBI chr 6:35,794,982...35,797,323
Ensembl chr 6:35,794,982...35,797,344 		JBrowse link
G CMIP c-Maf inducing protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr16:81,444,808...81,711,762
Ensembl chr16:81,444,808...81,711,762 		JBrowse link
G CNKSR2 connector enhancer of kinase suppressor of Ras 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr  X:21,374,418...21,654,689
Ensembl chr  X:21,372,801...21,654,695 		JBrowse link
G CNR1 cannabinoid receptor 1 IMP RGD PMID:18678611 RGD:2314632 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G COL3A1 collagen type III alpha 1 chain ISO RGD PMID:20836762 RGD:7257556 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G CP ceruloplasmin IEP protein:increased expression:serum RGD PMID:19834873 RGD:2314681 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CPB2 carboxypeptidase B2 IEP protein:increased expression, increased activity:plasma RGD PMID:11836301 RGD:2313645 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033 		JBrowse link
G CPE carboxypeptidase E no_association
onset		 IAGP no association between obesity or diabetes and three SNPs (-53G>T, -144G>A, 219G>A) in Japanese patients
DNA:SNP:CDS:847C>T, amino acid R283W; earlier age of onset in heterozygotes in an four Ashkenazi families
DNA:SNP:cds (rs1583645) (human)		 RGD PMID:9662053 PMID:11462236 PMID:23776430 RGD:1626184, RGD:1626183, RGD:405650683 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16123366 PMID:19553925 RGD:2311344 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO mRNA:decreased expression:hypothalamus (rat) RGD PMID:20472052 RGD:5507823 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G CRP C-reactive protein IEP RGD PMID:16764962 RGD:9491772 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CRTC2 CREB regulated transcription coactivator 2 treatment ISO RGD PMID:23595987 PMID:19706791 RGD:9685169, RGD:9685172 NCBI chr 1:153,947,675...153,958,612
Ensembl chr 1:153,947,669...153,958,615 		JBrowse link
G CST3 cystatin C IEP protein:increased expression:serum (human) RGD PMID:19887833 RGD:2314295 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473 		JBrowse link
G CTF1 cardiotrophin 1 ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr16:30,895,846...30,903,560
Ensembl chr16:30,896,614...30,903,547 		JBrowse link
G CTSB cathepsin B IEP mRNA:decreased expression:pancreatic islet (human) RGD PMID:19367387 RGD:2315527 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSL cathepsin L susceptibility IEP
ISO		 protein:increased expression:right auricular appendage (human)
mRNA:increased expression:gastrocnemius muscle (mouse)		 RGD PMID:19074676 PMID:12941783 RGD:2315622, RGD:2315625 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 IEP RGD PMID:19187771 RGD:2311356 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:plasma RGD PMID:18451752 RGD:2306553 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CYB5R4 cytochrome b5 reductase 4 IAGP
ISS		 DNA:deletion:intron:IVSV+7TC (human)
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 MouseDO
RGD		 PMID:15504981 RGD:2315647 NCBI chr 6:83,859,689...83,967,423
Ensembl chr 6:83,859,656...83,967,423 		JBrowse link
G CYBA cytochrome b-245 alpha chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:15531508 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:decreased expression:testis, Leydig cell (rat) RGD PMID:18481435 RGD:4889107 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 IAGP DNA:polymorphism:promoter:-344C>T (human) RGD PMID:18771471 RGD:2307288 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP DNA:polymorphism:3' UTR:5639T>C (human) RGD PMID:11996959 RGD:2307073 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22244987 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment ISO RGD PMID:32742601 RGD:124713564 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 IAGP DNA:polymorphism:cds:I359L (human) RGD PMID:16325295 RGD:2307152 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO
IEP		 mRNA:decreased expression:liver
mRNA, protein:decreased expression:liver
mRNA:increased expression:leukocyte		 RGD PMID:10049703 PMID:10679205 PMID:12534643 RGD:2313688, RGD:2313687, RGD:2313686 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22244987 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DAG1 dystroglycan 1 ISO protein:decreased expression:skeletal muscle RGD PMID:16323284 RGD:1581689 NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618 		JBrowse link
G DCN decorin IEP protein:increased expression:plasma RGD PMID:18414424 RGD:2311410 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DCX doublecortin ISO protein:decreased expression:dentate gyrus RGD PMID:18982449 RGD:12904763 NCBI chr  X:111,293,779...111,412,192
Ensembl chr  X:111,293,779...111,412,429 		JBrowse link
G DEFB1 defensin beta 1 ISO RGD PMID:14521940 RGD:4892271 NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936 		JBrowse link
G DGKD diacylglycerol kinase delta EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr 2:233,354,494...233,472,098
Ensembl chr 2:233,354,494...233,472,104 		JBrowse link
G DIO2 iodothyronine deiodinase 2 no_association IAGP DNA:SNP: :rs225014, p.T92A (human) RGD PMID:17077128 RGD:1626439 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DLL3 delta like canonical Notch ligand 3 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,498,947...39,508,469
Ensembl chr19:39,498,895...39,508,481 		JBrowse link
G DNM1L dynamin 1 like treatment ISO RGD PMID:21820301 RGD:11561956 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA:increased expression:liver: RGD PMID:21818837 RGD:7207079 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DPP4 dipeptidyl peptidase 4 IMP RGD PMID:19705345 RGD:2313700 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394 		JBrowse link
G DRD2 dopamine receptor D2 IAGP DNA:polymorphism:exon:32806C>T (human) RGD PMID:18834717 RGD:2311601 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,825,350...39,834,162
Ensembl chr19:39,825,350...39,834,201 		JBrowse link
G ECE1 endothelin converting enzyme 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16387788 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G ECH1 enoyl-CoA hydratase 1 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841 		JBrowse link
G EDN1 endothelin 1 ISO
IEP
EXP		 protein:increased expression:mesenteric artery
mRNA:increased expression:blood vessel endothelial cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16387788 PMID:19286964 PMID:19581418 RGD:2313280, RGD:2313278 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A ISO
EXP		 protein:increased expression:mesenteric artery
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16387788 PMID:19286964 RGD:2313280 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16387788 PMID:19286964 RGD:2313280 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EGFR epidermal growth factor receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:22238402 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EID2 EP300 interacting inhibitor of differentiation 2 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,538,707...39,540,161
Ensembl chr19:39,538,707...39,540,161 		JBrowse link
G EID2B EP300 interacting inhibitor of differentiation 2B IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,530,987...39,532,852
Ensembl chr19:39,530,987...39,532,852 		JBrowse link
G EIF3F eukaryotic translation initiation factor 3 subunit F ISO RGD PMID:12875716 RGD:10755506 NCBI chr11:7,987,337...8,001,852
Ensembl chr11:7,970,251...8,001,862 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 susceptibility IAGP
EXP		 NIDDM,OMIM:125853;DNA:polymorphism
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset | ClinVar Annotator: match by term: Type II diabetes mellitus		 ClinVar
CTD
OMIM
RGD		 PMID:9662402 PMID:10453738 PMID:10480624 PMID:11739459 PMID:11771660 More... RGD:1601042 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155 		JBrowse link
G EP300 E1A binding protein p300 ISO protein:increased serine phosphorylation:renal glomerulus (mouse) RGD PMID:23737551 RGD:7257568 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:17914354 RGD:10395377 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPC2 enhancer of polycomb homolog 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr 2:148,644,751...148,787,569
Ensembl chr 2:148,644,440...148,787,569 		JBrowse link
G EPO erythropoietin IEP protein:decreased expression:plasma
mRNA:increased expression:retina		 RGD PMID:16911620 PMID:16936148 RGD:2313842, RGD:2313840 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G ESR1 estrogen receptor 1 IAGP DNA:polymorphism
DNA:snps:introns: rs3020314, rs985694, rs1884051(human)		 RGD PMID:17097034 PMID:18854778 RGD:2314012, RGD:2314003 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESRRA estrogen related receptor alpha no_association IAGP RGD PMID:16755280 RGD:1625637 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor IEP
ISO
EXP		 protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:30718926 PMID:19225563 PMID:19225563 RGD:2313847, RGD:2313847 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G F12 coagulation factor XII IEP protein:increased activity:plasma (human) RGD PMID:7974333 RGD:2312416 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583 		JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:plasma
associated with Myocardial Infarction		 RGD PMID:17971179 PMID:18487475 RGD:2313852, RGD:2313851 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:increased activity:plasma RGD PMID:17785358 RGD:2312381 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F7 coagulation factor VII susceptibility
no_association		 IDA
ISO
IEP		 protein:increased activity:plasma (human)
associated with Kidney Failure; protein:increased expression:plasma (human)
associated with Brain Infarction; protein:increased activity:plasma (human)		 RGD PMID:11689270 PMID:14614217 PMID:17785358 PMID:10332679 PMID:11137328 More... RGD:2312382, RGD:2312394, RGD:2312381, RGD:2312388, RGD:2312386, RGD:2312383, RGD:2312380 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G F8 coagulation factor VIII IEP protein:increased activity:plasma (human) RGD PMID:7974333 RGD:2312416 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940 		JBrowse link
G F9 coagulation factor IX IEP protein:increased activity:plasma (human) RGD PMID:7974333 RGD:2312416 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459 		JBrowse link
G FABP2 fatty acid binding protein 2 no_association IAGP DNA:polymorphism:CDS:amino acid A54T, in a population from urban south India RGD PMID:16919542 RGD:1626401 NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138 		JBrowse link
G FABP3 fatty acid binding protein 3 susceptibility IAGP DNA:deletion:3' utr:c.634+483delT (human) RGD PMID:12872269 RGD:1578461 NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850 		JBrowse link
G FAM234A family with sequence similarity 234 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr16:234,821...269,963
Ensembl chr16:234,521...272,183 		JBrowse link
G FAS Fas cell surface death receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand IAGP DNA:repeats:3' utr (human) RGD PMID:16691186 RGD:2315750 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBL fibrillarin IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,834,458...39,846,379
Ensembl chr19:39,834,458...39,846,379 		JBrowse link
G FBN1 fibrillin 1 ISO RGD PMID:20836762 RGD:7257556 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721 		JBrowse link
G FBXO17 F-box protein 17 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,941,401...38,975,742
Ensembl chr19:38,941,401...38,975,742 		JBrowse link
G FBXO27 F-box protein 27 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,005,842...39,032,549
Ensembl chr19:38,990,714...39,032,785 		JBrowse link
G FCGBP Fc gamma binding protein IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,863,323...39,934,634
Ensembl chr19:39,863,323...39,934,626 		JBrowse link
G FEM1B fem-1 homolog B ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr15:68,277,745...68,295,862
Ensembl chr15:68,277,745...68,295,862 		JBrowse link
G FFAR1 free fatty acid receptor 1 ameliorates IMP
IDA		 RGD PMID:19401434 PMID:19758793 RGD:150517551, RGD:2315761 NCBI chr19:35,347,902...35,353,864
Ensembl chr19:35,347,902...35,353,864 		JBrowse link
G FGA fibrinogen alpha chain IEP protein:increased activity:plasma (human) RGD PMID:7974333 RGD:2312416 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGB fibrinogen beta chain IEP protein:increased expression:plasma RGD PMID:7974333 RGD:2312416 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FGF2 fibroblast growth factor 2 IEP protein:increased expression:serum RGD PMID:18279437 RGD:2315844 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF21 fibroblast growth factor 21 treatment ISO
EXP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:26797127 PMID:21293445 RGD:10401914 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:22174314 RGD:10401888 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FGG fibrinogen gamma chain IEP protein:increased activity:plasma (human) RGD PMID:7974333 RGD:2312416 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO mRNA, protein:decreased expression:skeletal muscle RGD PMID:17823371 RGD:2313719 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FOXA2 forkhead box A2 no_association IAGP DNA:SNP, repeat: :rs1055080 (human)
DNA:transversion, transitions:promoter, exon:multiple
DNA:missense mutation:p.A86T (human)		 RGD PMID:18797817 PMID:10868949 PMID:11043867 RGD:2313242, RGD:2313246, RGD:2313245 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455 		JBrowse link
G FOXC2 forkhead box C2 no_association IAGP DNA:polymorphism:5'ut:-512C>T,-350G>T, 3'ut:1548C>T
DNA:insertion:1006insA		 RGD PMID:12540636 PMID:15523639 RGD:1601220, RGD:1601217 NCBI chr16:86,566,829...86,569,728
Ensembl chr16:86,566,829...86,569,728 		JBrowse link
G FOXM1 forkhead box M1 ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXO1 forkhead box O1 treatment ISO protein:altered localization:nucleus, islet cell: RGD PMID:22417654 PMID:20736318 RGD:10044264, RGD:10044265 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FRZB frizzled related protein IEP protein, decreased expression:skeletal muscle, serum (human) RGD PMID:28240822 RGD:32716394 NCBI chr 2:182,833,275...182,866,637
Ensembl chr 2:182,833,275...182,866,637 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase susceptibility
no_association		 EXP
IAGP
IEP		 CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs17817449 (human)
DNA:SNP: :rs9939609 (human)
DNA:SNP: :rs1421085 (human)
DNA:SNP:intron:rs9939609 (human)
DNA:SNPs: :multiple
mRNA:increased expression:blood		 CTD
RGD		 PMID:23104008 PMID:29154870 PMID:21294771 PMID:32061761 PMID:28890888 More... RGD:329813082, RGD:329901762, RGD:329901771, RGD:329901773, RGD:329901856, RGD:329951010 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G FUCA1 alpha-L-fucosidase 1 IEP protein:increased activity:serum RGD PMID:16176171 RGD:2315931 NCBI chr 1:23,845,077...23,868,290
Ensembl chr 1:23,845,077...23,868,290 		JBrowse link
G FXN frataxin no_association IAGP DNA:repeats:intron:GAA (human) RGD PMID:10102715 PMID:9588463 RGD:2307051, RGD:2307050 NCBI chr 9:69,035,752...69,079,076
Ensembl chr 9:69,035,751...69,079,076 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 ISO
IEP		 protein:increased activity:liver RGD PMID:16396963 PMID:10866049 PMID:8865366 RGD:2315959, RGD:2315966, RGD:728661 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase IEP protein:decreased expression:reticulocyte, erythrocyte RGD PMID:12853069 RGD:2307349 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GADD45GIP1 GADD45G interacting protein 1 ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr19:12,953,119...12,957,223
Ensembl chr19:12,953,119...12,957,223 		JBrowse link
G GAL galanin and GMAP prepropeptide IEP protein:increased expression:blood RGD PMID:15735230 RGD:2313738 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO protein:decreased acetylation RGD PMID:28258188 RGD:13792662 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GCG glucagon EXP CTD Direct Evidence: marker/mechanism CTD PMID:23466488 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404 		JBrowse link
G GCGR glucagon receptor IAGP DNA:mutation:exon:G40S
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar
RGD		 PMID:7773293 PMID:8563746 PMID:28492532 PMID:7773293 RGD:1625208 NCBI chr17:81,804,150...81,814,008
Ensembl chr17:81,804,132...81,814,008 		JBrowse link
G GCH1 GTP cyclohydrolase 1 IAGP DNA:SNPs,haplotypes: :multiple RGD PMID:25369080 RGD:329961331 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GCK glucokinase no_association
treatment		 IAGP
ISO
EXP
ISS		 DNA:polymorphisms:multiple:no association between multiple SSLP and SNP alleles and T2DM in a Japanese population
MODY2, OMIM:125851;DNA:point mutation:E279X
DNA:polymorphisms::significant association between alleles of two SSLPs and T2DM in a Japanese population
DNA:microsatellite marker genotypes:3', 5':no association between genotypes of upstream or downstream microsatellite markers and T2DM in Welsh Caucasians
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 OMIM
CTD
ClinVar
MouseDO
RGD		 PMID:1360036 PMID:1397713 PMID:1502186 PMID:2555564 PMID:7553875 More... RGD:2301887, RGD:1601292, RGD:2301889, RGD:2301883, RGD:7488969 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GCKR glucokinase regulator IMP
IAGP
EXP		 DNA:SNP::rs1260326(human)
DNA:polymorphism: :rs780094 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20081858 PMID:11473043 PMID:18556336 PMID:19241058 PMID:21411509 RGD:2315986, RGD:2315985, RGD:2315983, RGD:7242280 NCBI chr 2:27,496,839...27,523,684
Ensembl chr 2:27,496,839...27,523,684 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit EXP CTD Direct Evidence: therapeutic CTD PMID:32715377 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit EXP CTD Direct Evidence: therapeutic CTD PMID:32715377 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 IEP RGD PMID:17574229 RGD:2313352 NCBI chr 2:69,319,780...69,387,227
Ensembl chr 2:69,319,780...69,387,250 		JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 susceptibility IAGP DNA:missense mutation, SNPs:exon, 3' utr:multiple RGD PMID:14764791 RGD:2307362 NCBI chr 5:180,300,698...180,353,336
Ensembl chr 5:180,300,698...180,353,336 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 IEP RGD PMID:19936701 RGD:2315593 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005 		JBrowse link
G GH1 growth hormone 1 treatment ISO RGD PMID:26379831 RGD:11352744 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839 		JBrowse link
G GHR growth hormone receptor IAGP DNA:deletion:exon (human) RGD PMID:17537658 RGD:2307363 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide susceptibility IAGP DNA:polymorphism: :p.L72M (human) RGD PMID:18848536 RGD:2313749 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G GIP gastric inhibitory polypeptide ISO
IDA		 disease in rat treated with human protein RGD PMID:18937625 PMID:19056762 PMID:19126188 PMID:19473824 RGD:2312589, RGD:2312529, RGD:2312591, RGD:2312587 NCBI chr17:48,958,554...48,968,596
Ensembl chr17:48,958,554...48,968,596 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor ISO
IEP		 protein:decreased expression:pancreatic islet (human) RGD PMID:11334402 PMID:19386626 RGD:68929, RGD:2312454 NCBI chr19:45,668,221...45,683,722
Ensembl chr19:45,668,221...45,683,722 		JBrowse link
G GJA1 gap junction protein alpha 1 ISO protein:increased phosphorylation:kidney RGD PMID:21573906 RGD:7207393 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GLIS3 GLIS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22158537 NCBI chr 9:3,824,127...4,490,465
Ensembl chr 9:3,824,127...4,348,392 		JBrowse link
G GLO1 glyoxalase I IAGP DNA:point mutation: :c.332A>C (human) RGD PMID:18413187 RGD:7242567 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145 		JBrowse link
G GLP1R glucagon like peptide 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303 		JBrowse link
G GMFG glia maturation factor gamma IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,328,359...39,336,043
Ensembl chr19:39,328,353...39,342,372 		JBrowse link
G GNB3 G protein subunit beta 3 IAGP
EXP		 DNA:polymorphism: :825C>T (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12511541 PMID:18656447 RGD:2313204 NCBI chr12:6,840,925...6,847,393
Ensembl chr12:6,839,954...6,847,393 		JBrowse link
G GP2 glycoprotein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr16:20,309,574...20,327,513
Ensembl chr16:20,309,574...20,327,808 		JBrowse link
G GP6 glycoprotein VI platelet IEP
IAGP		 protein:increased expression:plasma (human)
associated with intermediate coronary syndrome;DNA:missense mutation:CDS: (rs1671152) (human)		 RGD PMID:33859620 PMID:33076381 RGD:401794568, RGD:401794569 NCBI chr19:55,013,705...55,038,264
Ensembl chr19:55,013,705...55,038,264 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:9070847 PMID:16123366 PMID:25741868 NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735 		JBrowse link
G GPT glutamic--pyruvic transaminase ISO protein:increased expression, activity:liver: RGD PMID:25865565 RGD:11342811 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 ISO protein:increased expression, activity:liver: RGD PMID:25865565 RGD:11342811 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289 		JBrowse link
G GPX1 glutathione peroxidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 PMID:23795780 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 treatment IDA
IEP		 protein:decreased expression:plasma (human) RGD PMID:18936159 PMID:18936159 PMID:24102912 RGD:2312632, RGD:2312632, RGD:401827847 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRB14 growth factor receptor bound protein 14 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
associated with Environmental Illness; DNA:SNP:: (rs13389219) (Human)		 CTD
RGD		 PMID:21874001 PMID:27281273 RGD:401850598 NCBI chr 2:164,492,417...164,621,482
Ensembl chr 2:164,492,417...164,621,482 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:20821187 PMID:27164497 RGD:10045562, RGD:13792739 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility
no_association		 IAGP
EXP		 DNA:deletion: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22652274 PMID:17979505 PMID:16413497 PMID:20739761 RGD:2306627, RGD:2306628, RGD:5490963 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:20739761 RGD:5490963 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP RGD PMID:17979505 RGD:2306627
G H19 H19 imprinted maternally expressed transcript sexual_dimorphism IEP RNA:decrased expression:blood serum (human) RGD PMID:33116722 RGD:243048436 NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,166...2,004,552 		JBrowse link
G HBA1 hemoglobin subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16632892 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522 		JBrowse link
G HDAC1 histone deacetylase 1 ISO protein:increased activity:kidney: RGD PMID:19553350 RGD:9590229 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC2 histone deacetylase 2 ISO protein:increased activity:kidney: RGD PMID:19553350 RGD:9590229 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HECTD4 HECT domain E3 ubiquitin protein ligase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35713687 NCBI chr12:112,160,195...112,382,431
Ensembl chr12:112,160,188...112,382,439 		JBrowse link
G HFE homeostatic iron regulator susceptibility IAGP DNA:missense mutation:cds:p.H63D (human)
associated with cystic fibrosis;DNA:missense mutation: :p.C282Y (human)		 RGD PMID:20097100 PMID:30291871 RGD:8694381, RGD:14701045 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,226...26,098,343 		JBrowse link
G HHEX hematopoietically expressed homeobox EXP CTD Direct Evidence: marker/mechanism CTD PMID:23104008 NCBI chr10:92,689,955...92,695,647
Ensembl chr10:92,689,955...92,695,647 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha susceptibility ISO
IAGP
IEP		 protein:increased expression:heart blood vessel
DNA:missense mutation:cds:p.P582S (human)
associated with Breast Neoplasms;protein:increased expression:serum (human)		 RGD PMID:12234789 PMID:16046581 PMID:23244125 PMID:17914354 RGD:625730, RGD:8695936, RGD:8695972, RGD:10395377 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIPK4 homeodomain interacting protein kinase 4 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:40,379,271...40,390,181
Ensembl chr19:40,379,271...40,390,181 		JBrowse link
G HK1 hexokinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HK2 hexokinase 2 IDA
ISO		 mRNA:decreased expression:epididymal fat pad, quadriceps RGD PMID:11319725 PMID:7813813 RGD:2313227, RGD:2313229 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP RGD PMID:16331578 RGD:2301814 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DRB5 major histocompatibility complex, class II, DR beta 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 6:32,517,353...32,530,287
Ensembl chr 6:32,517,353...32,530,287 		JBrowse link
G HMG20A high mobility group 20A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21874001 NCBI chr15:77,420,888...77,520,050
Ensembl chr15:77,420,412...77,485,607 		JBrowse link
G HMGA1 high mobility group AT-hook 1 susceptibility EXP
IAGP
ISS		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
ClinVar
OMIM
MouseDO		 PMID:15924147 PMID:21364139 PMID:23512162 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase IAGP
ISO		 DNA:polymorphism (human) RGD PMID:17870053 PMID:15312879 RGD:2313753, RGD:2313759 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 treatment IAGP
ISO
EXP		 DNA:repeat:promoter
associated with Obesity
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:12136229 PMID:16123366 PMID:16959961 PMID:17991645 PMID:23731386 RGD:10755699, RGD:8695927 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF1A HNF1 homeobox A susceptibility
onset		 IAGP
EXP
ISS		 Maturity-onset diabetes of the young type III, OMIM:600496;DNA:insertions, deletions, point mutations: :multiple
DNA:SNP::rs1169288 associated with future risk of developing T2DM (p=0.0002) in individuals from the Botnia study in Finland and the Malmo project in Sweden
DNA:deletions:exon:multiple
DNA:nonsense mutations, missense mutations: :multiple
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Insulin-resistant diabetes mellitus
DNA:SNP:cds: p.G319S (human)
associated with nicotine dependence; DNA:SNP:cds: p.G319S (human)
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036
ClinVar Annotator: match by term: Type II diabetes mellitus
ClinVar Annotator: match by term: DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST		 OMIM
CTD
ClinVar
MouseDO
RGD		 PMID:8945470 PMID:9112026 PMID:9133564 PMID:9287053 PMID:9313764 More... RGD:1601479, RGD:2301863, RGD:2301828, RGD:2301827, RGD:329901814, RGD:329901816, RGD:329901835 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HNF1B HNF1 homeobox B susceptibility
no_association		 IAGP
EXP		 DNA:deletions:cds:multiple (human)
renal cysts and diabetes syndrome, OMIM:137920;DNA:splice-site mutation:intron:IVS2+1G>A
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Type II diabetes mellitus
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset
ClinVar Annotator: match by term: Type 2 diabetes mellitus | ClinVar Annotator: match by term: Type II diabetes mellitus		 OMIM
CTD
ClinVar
RGD		 PMID:9398836 PMID:12148114 PMID:12161522 PMID:15068978 PMID:15509593 More... RGD:2312748, RGD:1601484, RGD:2312750 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha susceptibility IAGP
ISO
EXP		 DNA:SNP::rs4810424 and rs3212198 nominally associated with future risk of developing T2DM (p=0.04) in individuals from the Botnia study in Finland and the Malmo project in Sweden
type I maturity-onset diabetes of the young, OMIM:125850; DNA:nonsense mutation:CDS:C->T, amino acid Q268X
DNA:SNPs:promoter:(human)
DNA:missense mutation:exon:p.T130I
protein:decreased expression:liver:
mRNA:decreased expression:liver,pancreas
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset		 OMIM
CTD
ClinVar
RGD		 PMID:9449683 PMID:10227563 PMID:10447526 PMID:10983627 PMID:12669197 More... RGD:2301863, RGD:1601637, RGD:2301836, RGD:2301839, RGD:12904769, RGD:12904770 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,836,370...38,852,347
Ensembl chr19:38,836,370...38,852,347 		JBrowse link
G HP haptoglobin treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16506275 PMID:19996384 RGD:6483015 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HPX hemopexin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16506275 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 susceptibility TAS
IAGP		 potential therapeutic target
DNA:SNPs:intron: (rs12086634,rs846910) (human)		 RGD PMID:16929377 PMID:28750217 RGD:1625075, RGD:329901909 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 IEP mRNA, protein:increased expression:skeletal muscle RGD PMID:17519316 RGD:2308922 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553 		JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 ISO mRNA:decreased expression:testis, Leydig cell (rat) RGD PMID:18481435 RGD:4889107 NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO mRNA:decreased expression:testis, Leydig cell (rat) RGD PMID:18481435 RGD:4889107 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO mRNA:decreased expression:testis, Leydig cell (rat) RGD PMID:18481435 RGD:4889107 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HSF1 heat shock transcription factor 1 ISO protein:increased expression:heart (mouse) RGD PMID:24496227 RGD:10402557 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B IAGP DNA:SNP:CDS:homozygous P2/P2 allele at position 1267 (p=0.001 for all diabetic patients, p=0.0012 for non-obese diabetic patients) RGD PMID:15223990 RGD:1626646 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 IEP protein:increased expression:serum (human) RGD PMID:22349026 RGD:6218966 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr  X:114,584,086...114,910,061
Ensembl chr  X:114,584,078...114,910,061 		JBrowse link
G IAPP islet amyloid polypeptide IEP
IMP
EXP
ISS		 protein:increased expression:pancreatic islet (human)
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
MouseDO
RGD		 PMID:16123366 PMID:23793354 PMID:19100955 PMID:18641056 PMID:2441214 RGD:2311446, RGD:2313359, RGD:9686128 NCBI chr12:21,354,959...21,379,980
Ensembl chr12:21,354,959...21,379,980 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO
IEP
EXP		 mRNA, protein:increased expression:aorta (rat)
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:24513509 PMID:20388520 PMID:18299691 RGD:4145422, RGD:2312766 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID1 inhibitor of DNA binding 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G IDE insulin degrading enzyme no_association IAGP
ISO		 DNA:SNP,haplotype::no association with 21 single-marker SNPs or with 13 multi-marker haplotypes in 4206 individuals from Scandinavia and Canada
DNA:haplotype::CC haplotype of SNPs rs2209972 and rs1887922 in men of European descent from the Framingham Heart Study
DNA:missense mutations, haplotype:exon:p.H18R, p.A890V (rat)
DNA:SNP:cds (rs6583813) (human)		 RGD PMID:16380485 PMID:12765971 PMID:12634421 PMID:10958757 PMID:23776430 RGD:1626698, RGD:1626697, RGD:737718, RGD:737717, RGD:405650683 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096 		JBrowse link
G IFNG interferon gamma IDA RGD PMID:18852529 RGD:2311491 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNL1 interferon lambda 1 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673 		JBrowse link
G IFNL2 interferon lambda 2 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,268,396...39,270,188
Ensembl chr19:39,268,396...39,270,188 		JBrowse link
G IFNL3 interferon lambda 3 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,455...39,245,250 		JBrowse link
G IGF1 insulin like growth factor 1 ISO
IDA		 RGD PMID:18986336 PMID:16005252 RGD:2306690, RGD:2313767 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:decreased expression:pancreas
protein:decreased expression:myocardium, blood vessel endothelial cell		 RGD PMID:17476475 PMID:18986336 RGD:2311504, RGD:2306690 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGF2 insulin like growth factor 2 ISO protein:decreased expression:pancreas RGD PMID:17476475 PMID:10727441 RGD:2311504, RGD:5510004 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:17463246 PMID:17463248 PMID:17463249 NCBI chr 3:185,643,130...185,825,042
Ensembl chr 3:185,643,130...185,825,042 		JBrowse link
G IGF2R insulin like growth factor 2 receptor susceptibility IAGP DNA:insertion, deletion:3' utr (human) RGD PMID:16868148 RGD:2311514 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 IDA RGD PMID:16005252 RGD:2313767 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta IDA RGD PMID:15685173 RGD:10045952 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 susceptibility IAGP
IEP		 DNA:polymorphisms:promoter:g.-1082G>A, g.-819C>T, g.-592C>A (human) RGD PMID:19031431 PMID:28843383 RGD:2308943, RGD:14975146 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535 		JBrowse link
G IL1B interleukin 1 beta susceptibility IAGP
IEP		 DNA:snp:exon:g.3968C>T rs1143634 (human) RGD PMID:21205020 PMID:28843383 RGD:7175255, RGD:14975146 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility
no_association
disease_progression		 IAGP DNA:repeats:intron:IVS2+914_1000dup IL1RN*2, IL1RN*3 (human)
DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
associated with Metabolic Syndrome X; DNA:snp:intron:IVS3+102A>G rs3213448 (human)		 RGD PMID:17069782 PMID:8786086 PMID:21205020 RGD:6907409, RGD:6907412, RGD:7175255 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL6 interleukin 6 IAGP
IEP
ISO
EXP		 DNA:polymorphism:promoter:-572C>G (human)
protein:increased expression:extracellular space (human)
mRNA:increased expression:adipose tissue
DNA, protein:SNP, increased expression:promoter:serum, -174G>C (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to		 CTD
ClinVar
OMIM
RGD		 PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More... RGD:2307270, RGD:2307266, RGD:2307269, RGD:14975285 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6-AS1 IL6 antisense RNA 1 IAGP ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to ClinVar PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More... NCBI chr 7:22,725,395...22,727,620
Ensembl chr 7:22,725,395...22,727,620 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 IAGP
EXP		 DNA:SNPs: :rs2276047,snp8(human)
DNA:deletion:3' utr (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12086927 PMID:25635986 PMID:15220217 PMID:12086927 RGD:1626127, RGD:633161 NCBI chr11:72,223,563...72,239,147
Ensembl chr11:72,223,701...72,239,147 		JBrowse link
G INS insulin IEP
IAGP
EXP
ISS		 DNA:polymorphism:promoter
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Type 2 diabetes mellitus
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
ClinVar
MouseDO
RGD		 PMID:3511099 PMID:7573102 PMID:11522680 PMID:11978674 PMID:15531508 More... RGD:2311112, RGD:1625120 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough IAGP
ISO		 ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:17047922 PMID:17855560 PMID:18162506 PMID:18171712 PMID:19586609 More... NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSR insulin receptor treatment ISO
IDA
IAGP		 protein:decreased expression:kidney
protein:increased serine phosphorylation, increased protein binding:liver
protein:decreased phosphorylation:vastus lateralis:phosphotyrosine (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Insulin-resistant diabetes mellitus		 ClinVar
RGD		 PMID:1607076 PMID:1845971 PMID:2040394 PMID:2884728 PMID:4413914 More... RGD:2290475, RGD:2307334, RGD:2307341, RGD:2307335, RGD:2307342, RGD:2307334, RGD:2307333, RGD:10403046, RGD:2314405 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IRS1 insulin receptor substrate 1 no_association IAGP
ISO
EXP
ISS		 DNA:point mutation:exon:T608R
DNA:polymorphisms: :p.P512A, p.G971R (human)
DNA:SNP:promoter:-446G>A, -7120G>A (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 ClinVar
CTD
MouseDO
RGD		 PMID:8104271 PMID:8723689 PMID:10430617 PMID:11775217 PMID:12679424 More... RGD:1624975, RGD:6482863, RGD:6483015, RGD:6483016, RGD:7207057 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G IRS2 insulin receptor substrate 2 IAGP
ISO
EXP
ISS		 DNA:polymorphism:exon:G1057D
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 OMIM
CTD
MouseDO
ClinVar
RGD		 PMID:10525667 PMID:11030756 PMID:11473060 PMID:11600548 PMID:25741868 More... RGD:1625023, RGD:10045938 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G ISL1 ISL LIM homeobox 1 IAGP
ISO		 associated with Obesity;DNA:SNP:promoter:g.-47A>G (human)
mRNA,protein:decreased expression:pancreas:		 RGD PMID:11978668 PMID:30341898 RGD:2311117, RGD:243065124 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730 		JBrowse link
G ITGA1 integrin subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr 5:52,787,916...52,959,209
Ensembl chr 5:52,787,916...52,959,209 		JBrowse link
G ITGA2 integrin subunit alpha 2 IDA
IEP		 protein:increased expression:platelet (human) RGD PMID:15025679 PMID:15025679 RGD:2307425, RGD:2307425 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779 		JBrowse link
G ITGAM integrin subunit alpha M ISO protein:increased expression:neutrophil (rat) RGD PMID:21699626 RGD:329902064 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITLN1 intelectin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23555749 NCBI chr 1:160,876,540...160,885,180
Ensembl chr 1:160,876,540...160,885,180 		JBrowse link
G JADE2 jade family PHD finger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 5:134,523,952...134,583,227
Ensembl chr 5:134,524,312...134,583,230 		JBrowse link
G JAZF1 JAZF zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18372903 NCBI chr 7:27,830,577...28,180,795
Ensembl chr 7:27,830,573...28,180,795 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 IAGP
TAS
ISO
EXP		 DNA:polymorphism: :p.E23K (human)
polymorphisms in the gene are linked to altered insulin secretion; E23K polymorphism appears to confer susceptibility to diabetes type-2 in Caucasian population
DNA:SNP
DNA:missense mutation::p.E23K (human)
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset | ClinVar Annotator: match by term: Type 2 diabetes mellitus		 CTD
ClinVar
OMIM
RGD		 PMID:1422196 PMID:9867219 PMID:11318841 PMID:11395395 PMID:11692183 More... RGD:2311534, RGD:2313610, RGD:2311533, RGD:2313628, RGD:12790969 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KCNK16 potassium two pore domain channel subfamily K member 16 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22158537 NCBI chr 6:39,314,570...39,322,968
Ensembl chr 6:39,314,698...39,322,968 		JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO protein:decreased expression:aorta RGD PMID:18790848 RGD:10412045 NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO protein:increased expression:aorta (rat) RGD PMID:21463632 RGD:401794561 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
associated with Environmental Illness; DNA:SNP:: (rs163184) (human)		 CTD
RGD		 PMID:18711366 PMID:18711367 PMID:26551672 PMID:27281273 RGD:401850598 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G KCNU1 potassium calcium-activated channel subfamily U member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 8:36,784,374...36,936,125
Ensembl chr 8:36,784,324...36,936,125 		JBrowse link
G KDR kinase insert domain receptor IEP protein:decreased expression:skin, blood vessel RGD PMID:17898089 RGD:5684411 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KIF6 kinesin family member 6 sexual_dimorphism IAGP DNA:SNP: :p.W719R (rs20455) (human) RGD PMID:25629058 RGD:243048454 NCBI chr 6:39,329,990...39,725,408
Ensembl chr 6:39,329,990...39,725,408 		JBrowse link
G KL klotho ISO
EXP		 mRNA:decreased expression:kidney:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28869590 PMID:23967103 RGD:10044235 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143 		JBrowse link
G KLF11 KLF transcription factor 11 IAGP DNA:polymorphisms: :p.Q62R, p.A347S, p.T220M (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar
RGD		 PMID:15774581 PMID:18199129 PMID:25741868 PMID:28492532 PMID:34393998 More... RGD:2311540 NCBI chr 2:10,043,550...10,054,836
Ensembl chr 2:10,042,849...10,054,836 		JBrowse link
G KLF14 KLF transcription factor 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29632379 NCBI chr 7:130,730,697...130,734,207
Ensembl chr 7:130,730,697...130,734,207 		JBrowse link
G KMT2D lysine methyltransferase 2D ISO RGD PMID:23826075 RGD:9588237 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794 		JBrowse link
G KSR2 kinase suppressor of ras 2 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 CTD
ClinVar		 PMID:24209692 PMID:25741868 PMID:30718926 NCBI chr12:117,453,012...117,968,990
Ensembl chr12:117,453,012...117,968,990 		JBrowse link
G LCN2 lipocalin 2 IEP protein:increased expression:serum: RGD PMID:19949414 RGD:126779589 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEP leptin susceptibility ISO
EXP
IAGP
ISS		 CTD Direct Evidence: therapeutic
DNA:SNP,haplotype:promoter,3'utr: -632G>A, +4998A>C (human)
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
MouseDO
RGD		 PMID:15070752 PMID:19289493 PMID:18564365 RGD:2311130, RGD:2311139 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor susceptibility
treatment		 IAGP
ISO
EXP
ISS		 DNA:insertion:3' utr (human)
DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
associated with nonalcoholic fatty liver disease;DNA:intron:c.2673+1118C>T (rs6700896) (human)
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
MouseDO
RGD		 PMID:20175764 PMID:22933112 PMID:24263156 PMID:26939912 PMID:17065694 More... RGD:2311144, RGD:2311141, RGD:10412018, RGD:13432147, RGD:14696694 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LEUTX leucine twenty homeobox IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,776,453...39,786,291
Ensembl chr19:39,776,595...39,786,291 		JBrowse link
G LGALS13 galectin 13 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,602,524...39,607,474
Ensembl chr19:39,602,524...39,607,474 		JBrowse link
G LGALS14 galectin 14 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,704,481...39,709,444
Ensembl chr19:39,704,481...39,709,444 		JBrowse link
G LGALS16 galectin 16 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,655,913...39,660,647
Ensembl chr19:39,655,913...39,660,647 		JBrowse link
G LGALS4 galectin 4 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,801,674...38,812,945
Ensembl chr19:38,801,671...38,812,945 		JBrowse link
G LGALS7 galectin 7 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,770,968...38,773,517
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754 		JBrowse link
G LGALS7B galectin 7B IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754 		JBrowse link
G LIPC lipase C, hepatic type susceptibility IAGP
IDA
EXP		 DNA:transition:promoter:-250G>A (human)
protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to		 OMIM
CTD
ClinVar
RGD		 PMID:1671786 PMID:1883393 PMID:8123642 PMID:8732782 PMID:12777476 More... RGD:2308830, RGD:2308826 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LIPE lipase E, hormone sensitive type IEP mRNA:decreased expression:subcutaneous adipose tissue RGD PMID:15609025 RGD:2313584 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388 		JBrowse link
G LMNA lamin A/C no_association IAGP DNA:SNPs RGD PMID:17327437 PMID:17327461 RGD:1624985, RGD:1624984 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,572...156,140,081 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO
IEP		 RGD PMID:16967782 PMID:11701721 RGD:2306436, RGD:2311542 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513 		JBrowse link
G LOC110121471 VISTA enhancer hs1977 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:25741868 NCBI chr11:17,412,970...17,415,128 JBrowse link
G LOC110121472 VISTA enhancer hs1980 IAGP ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar PMID:16415884 PMID:17206141 PMID:17245407 PMID:17460697 PMID:17463248 More... NCBI chr10:112,997,945...112,998,897 JBrowse link
G LOC114803475 PPARG eExon liver enhancer IAGP ClinVar Annotator: match by term: Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigricans and Hypertension ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:12,405,503...12,406,702 JBrowse link
G LOC126807011 MED14-independent group 3 enhancer GRCh37_chr4:26407341-26408540 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:29924900 NCBI chr 4:26,405,719...26,406,918 JBrowse link
G LOC126859963 BRD4-independent group 4 enhancer GRCh37_chr7:22766269-22767468 IAGP ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to ClinVar PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More... NCBI chr 7:22,726,650...22,727,849 JBrowse link
G LOC126862549 BRD4-independent group 4 enhancer GRCh37_chr17:36093401-36094600 IAGP ClinVar Annotator: match by term: Type II diabetes mellitus
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar PMID:19639018 PMID:23539225 PMID:24897035 PMID:25536396 PMID:25700310 More... NCBI chr17:37,733,408...37,734,611 JBrowse link
G LPL lipoprotein lipase treatment IAGP
IEP
ISO		 DNA:SNP:intron:13836C>A (rs343) (human)
associated with Obesity		 RGD PMID:8641022 PMID:18985010 PMID:18321693 PMID:29981201 RGD:1580537, RGD:2313298, RGD:2313304, RGD:13793399 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G LRFN1 leucine rich repeat and fibronectin type III domain containing 1 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,306,566...39,320,863
Ensembl chr19:39,306,566...39,320,863 		JBrowse link
G LTA lymphotoxin alpha onset
no_association		 IAGP DNA:polymorphism: :p.T60N (human) RGD PMID:15729581 PMID:16132956 RGD:1625033, RGD:2313261 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G MADD MAP kinase activating death domain ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr11:47,269,188...47,330,031
Ensembl chr11:47,269,161...47,330,031 		JBrowse link
G MAEA macrophage erythroblast attacher, E3 ubiquitin ligase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22158537 NCBI chr 4:1,289,891...1,340,137
Ensembl chr 4:1,289,887...1,340,147 		JBrowse link
G MAFA MAF bZIP transcription factor A IEP
ISO
ISS		 protein:decreased expression:islet:
protein:decreased expression:beta cells of pancrea
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 MouseDO
RGD		 PMID:24013263 PMID:20424231 RGD:13506742, RGD:13506745 NCBI chr 8:143,428,064...143,430,732
Ensembl chr 8:143,419,182...143,430,732 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:21820301 RGD:11561956 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAP3K10 mitogen-activated protein kinase kinase kinase 10 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:40,191,426...40,215,575
Ensembl chr19:40,191,426...40,215,575 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ISO protein:increased activity:serum: RGD PMID:28724746 RGD:151356966 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO protein:hyperphosphorylation:pancreas:
protein:increased expression:dorsal horn:
protein:hypophosphorylation:pancreatic islet:		 RGD PMID:26860984 PMID:27259299 PMID:28757391 PMID:21911753 PMID:19164460 RGD:13506775, RGD:13506776, RGD:13506777, RGD:13506785, RGD:13506786 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO protein:hypophosphorylation:pancreatic islet:
protein:hyperphosphorylation:pancreas:
protein:increased expression:dorsal horn:		 RGD PMID:21911753 PMID:26860984 PMID:27259299 PMID:28757391 PMID:19164460 RGD:13506785, RGD:13506775, RGD:13506776, RGD:13506777, RGD:13506786 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO
IDA		 protein:hyperphosphorylation:pancreatic islet: RGD PMID:21911753 PMID:21911753 RGD:13506785, RGD:13506785 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 IAGP
EXP		 ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 OMIM
ClinVar
CTD		 PMID:10700186 NCBI chr11:45,885,651...45,906,465
Ensembl chr11:45,885,651...45,906,465 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO
IDA		 protein:hyperphosphorylation:pancreatic islet: RGD PMID:21911753 PMID:21911753 RGD:13506785, RGD:13506785 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MAT1A methionine adenosyltransferase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23665415 NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658 		JBrowse link
G MATN4 matrilin 4 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar NCBI chr20:45,293,450...45,308,684
Ensembl chr20:45,293,445...45,308,529 		JBrowse link
G MED29 mediator complex subunit 29 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,391,378...39,400,641
Ensembl chr19:39,391,303...39,400,641 		JBrowse link
G MFN2 mitofusin 2 IEP mRNA:decreased expression:skeletal muscle tissue (human) RGD PMID:16123358 RGD:13204820 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIF macrophage migration inhibitory factor ISO mRNA, protein:increased expression:kidney cortex, epithelial cell RGD PMID:16571782 RGD:1641984 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR10B microRNA 10b EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 2:176,150,303...176,150,412
Ensembl chr 2:176,150,303...176,150,412 		JBrowse link
G MIR122 microRNA 122 IEP miRNA:increased expression:serum RGD PMID:27899485 RGD:14401601 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158 		JBrowse link
G MIR1226 microRNA 1226 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 3:47,849,555...47,849,629
Ensembl chr 3:47,849,555...47,849,629 		JBrowse link
G MIR1228 microRNA 1228 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr12:57,194,504...57,194,576
Ensembl chr12:57,194,504...57,194,576 		JBrowse link
G MIR1249 microRNA 1249 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr22:45,200,954...45,201,019
Ensembl chr22:45,200,954...45,201,019 		JBrowse link
G MIR125B1 microRNA 125b-1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr11:122,099,757...122,099,844
Ensembl chr11:122,099,757...122,099,844 		JBrowse link
G MIR126 microRNA 126 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686 		JBrowse link
G MIR1260A microRNA 1260a EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:77,266,218...77,266,290
Ensembl chr14:77,266,218...77,266,290 		JBrowse link
G MIR1260B microRNA 1260b EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:96,341,438...96,341,526
Ensembl chr11:96,341,438...96,341,526 		JBrowse link
G MIR127 microRNA 127 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:100,882,979...100,883,075
Ensembl chr14:100,882,979...100,883,075 		JBrowse link
G MIR1296 microRNA 1296 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:63,372,957...63,373,048
Ensembl chr10:63,372,957...63,373,048 		JBrowse link
G MIR1301 microRNA 1301 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 2:25,328,640...25,328,721
Ensembl chr 2:25,328,640...25,328,721 		JBrowse link
G MIR1306 microRNA 1306 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr22:20,086,058...20,086,142
Ensembl chr22:20,086,058...20,086,142 		JBrowse link
G MIR1307 microRNA 1307 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:103,394,253...103,394,401
Ensembl chr10:103,394,253...103,394,401 		JBrowse link
G MIR130B microRNA 130b EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr22:21,653,304...21,653,385
Ensembl chr22:21,653,304...21,653,385 		JBrowse link
G MIR140 microRNA 140 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR141 microRNA 141 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr12:6,964,097...6,964,191
Ensembl chr12:6,964,097...6,964,191 		JBrowse link
G MIR142 microRNA 142 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr17:58,331,232...58,331,318
Ensembl chr17:58,331,232...58,331,318 		JBrowse link
G MIR144 microRNA 144 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618 		JBrowse link
G MIR146B microRNA 146b IEP RNA:increased expression:arteriole RGD PMID:29374012 RGD:13702880 NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584 		JBrowse link
G MIR151A microRNA 151a EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:140,732,564...140,732,653
Ensembl chr 8:140,732,564...140,732,653 		JBrowse link
G MIR155 microRNA 155 IEP miRNA:decreased expression:serum RGD PMID:30852102 PMID:27711113 RGD:21079478, RGD:25671464 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR17HG miR-17-92a-1 cluster host gene EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr13:91,347,687...91,354,577
Ensembl chr13:91,347,686...91,397,592 		JBrowse link
G MIR181C microRNA 181c EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808 		JBrowse link
G MIR1908 microRNA 1908 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:61,815,161...61,815,240
Ensembl chr11:61,815,161...61,815,240 		JBrowse link
G MIR192 microRNA 192 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246 		JBrowse link
G MIR195 microRNA 195 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr17:7,017,615...7,017,701
Ensembl chr17:7,017,615...7,017,701 		JBrowse link
G MIR200A microRNA 200a EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952 		JBrowse link
G MIR203A microRNA 203a EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:104,117,405...104,117,514
Ensembl chr14:104,117,405...104,117,514 		JBrowse link
G MIR204 microRNA 204 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:70,809,975...70,810,084
Ensembl chr 9:70,809,975...70,810,084 		JBrowse link
G MIR205 microRNA 205 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:209,432,133...209,432,242
Ensembl chr 1:209,432,133...209,432,242 		JBrowse link
G MIR2116 microRNA 2116 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr15:59,171,183...59,171,262
Ensembl chr15:59,171,183...59,171,262 		JBrowse link
G MIR214 microRNA 214 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MIR215 microRNA 215 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:220,117,853...220,117,962
Ensembl chr 1:220,117,853...220,117,962 		JBrowse link
G MIR221 microRNA 221 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G MIR222 microRNA 222 EXP
ISO		 CTD Direct Evidence: marker/mechanism
associated with Femoral Fractures;RNA:increased expression:femur		 CTD
RGD		 PMID:24478399 PMID:28545106 PMID:31691506 RGD:151893486 NCBI chr  X:45,747,015...45,747,124
Ensembl chr  X:45,747,015...45,747,124 		JBrowse link
G MIR223 microRNA 223 severity IEP
ISO		 RNA:increased expression:pancreatic islet RGD PMID:31118273 PMID:31118273 RGD:25823139, RGD:25823139 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR27A microRNA 27a EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517 		JBrowse link
G MIR29A microRNA 29a IEP RNA:increased expression:arteriole
RNA:incrased expression:blood serum (human)		 RGD PMID:29374012 PMID:33116722 RGD:13702880, RGD:243048436 NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810 		JBrowse link
G MIR29B1 microRNA 29b-1 IEP RNA:increased expression:arteriole
RNA:increased expression:blood serum (human)		 RGD PMID:29374012 PMID:33116722 RGD:13702880, RGD:243048436 NCBI chr 7:130,877,459...130,877,539
Ensembl chr 7:130,877,459...130,877,539 		JBrowse link
G MIR30A microRNA 30a EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621 		JBrowse link
G MIR3173 microRNA 3173 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:95,137,919...95,137,986
Ensembl chr14:95,137,919...95,137,986 		JBrowse link
G MIR335 microRNA 335 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 7:130,496,111...130,496,204
Ensembl chr 7:130,496,111...130,496,204 		JBrowse link
G MIR339 microRNA 339 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 7:1,022,933...1,023,026
Ensembl chr 7:1,022,933...1,023,026 		JBrowse link
G MIR33B microRNA 33b EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr17:17,813,836...17,813,931
Ensembl chr17:17,813,836...17,813,931 		JBrowse link
G MIR375 microRNA 375 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 2:219,001,645...219,001,708
Ensembl chr 2:219,001,645...219,001,708 		JBrowse link
G MIR377 microRNA 377 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:101,062,050...101,062,118
Ensembl chr14:101,062,050...101,062,118 		JBrowse link
G MIR409 microRNA 409 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:101,065,300...101,065,378
Ensembl chr14:101,065,300...101,065,378 		JBrowse link
G MIR423 microRNA 423 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172 		JBrowse link
G MIR432 microRNA 432 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:100,884,483...100,884,576
Ensembl chr14:100,884,483...100,884,576 		JBrowse link
G MIR4482 microRNA 4482 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:104,268,336...104,268,405
Ensembl chr10:104,268,336...104,268,405 		JBrowse link
G MIR4516 microRNA 4516 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr16:2,133,119...2,133,204
Ensembl chr16:2,133,119...2,133,204 		JBrowse link
G MIR483 microRNA 483 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:2,134,134...2,134,209
Ensembl chr11:2,134,134...2,134,209 		JBrowse link
G MIR485 microRNA 485 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:101,055,419...101,055,491
Ensembl chr14:101,055,419...101,055,491 		JBrowse link
G MIR487B microRNA 487b EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:101,046,455...101,046,538
Ensembl chr14:101,046,455...101,046,538 		JBrowse link
G MIR532 microRNA 532 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24478399 NCBI chr  X:50,003,148...50,003,238
Ensembl chr  X:50,003,148...50,003,238 		JBrowse link
G MIR628 microRNA 628 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr15:55,372,940...55,373,034
Ensembl chr15:55,372,940...55,373,034 		JBrowse link
G MIR6741 microRNA 6741 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:225,922,080...225,922,142
Ensembl chr 1:225,922,080...225,922,142 		JBrowse link
G MIR6803 microRNA 6803 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr19:55,245,186...55,245,250
Ensembl chr19:55,245,186...55,245,250 		JBrowse link
G MIR744 microRNA 744 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr17:12,081,899...12,081,996
Ensembl chr17:12,081,899...12,081,996 		JBrowse link
G MIR7704 microRNA 7704 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 2:176,188,843...176,188,901
Ensembl chr 2:176,188,843...176,188,901 		JBrowse link
G MIR8061 microRNA 8061 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr19:54,645,309...54,645,383
Ensembl chr19:54,645,309...54,645,383 		JBrowse link
G MIR885 microRNA 885 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562 		JBrowse link
G MIR92B microRNA 92b EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:155,195,177...155,195,272
Ensembl chr 1:155,195,177...155,195,272 		JBrowse link
G MIR939 microRNA 939 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:144,394,149...144,394,230
Ensembl chr 8:144,394,149...144,394,230 		JBrowse link
G MIR98 microRNA 98 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:53,556,223...53,556,341
Ensembl chr  X:53,556,223...53,556,341 		JBrowse link
G MIRLET7D microRNA let-7d EXP CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:94,178,834...94,178,920
Ensembl chr 9:94,178,834...94,178,920 		JBrowse link
G MKI67 marker of proliferation Ki-67 ISO protein:increased expression:hippocampus RGD PMID:20045412 RGD:2317709 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MLXIPL MLX interacting protein like ISO protein:increased expression:liver (rat) RGD PMID:30029691 RGD:401799626 NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543 		JBrowse link
G MMP1 matrix metallopeptidase 1 IEP
ISO		 protein:decreased expression:renal glomerulus (human)
protein:increased expression:nucleus pulposus		 RGD PMID:19506087 PMID:19951028 RGD:2312464, RGD:7207379 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased expression:plasma (human) RGD PMID:17320450 RGD:7207195 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 treatment ISO RGD PMID:23204894 RGD:8694120 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment IEP
ISO		 protein:increased expression:plasma (human) RGD PMID:17320450 PMID:18552985 PMID:23204894 RGD:7207195, RGD:8547849, RGD:8694120 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPST mercaptopyruvate sulfurtransferase ISO RGD PMID:20127051 RGD:5134362 NCBI chr22:37,019,742...37,029,815
Ensembl chr22:37,019,635...37,029,821 		JBrowse link
G MRAS muscle RAS oncogene homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 3:138,347,648...138,405,535
Ensembl chr 3:138,347,648...138,405,534 		JBrowse link
G MRPS12 mitochondrial ribosomal protein S12 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,930,944...38,933,168
Ensembl chr19:38,930,944...38,933,168 		JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II ISO mRNA:decreased expression:soleus RGD PMID:14563825 RGD:2300410 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269 		JBrowse link
G MT-CYB mitochondrially encoded cytochrome b ISO mRNA:decreased expression:pancreatic islet RGD PMID:7588317 RGD:2298962 NCBI chr MT:14,747...15,887
Ensembl chr MT:14,747...15,887 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 IAGP
ISO		 DNA:SNP: :3394T>C (human)
DNA:polymorphism: :3316G>A, 3394T>C (human)
mRNA, protein:decreased expression:soleus, mitochondrion		 RGD PMID:18679013 PMID:15265369 PMID:14563825 RGD:2311583, RGD:2311592, RGD:2300410 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G MT-TL1 mitochondrially encoded tRNA-Leu (UUA/G) 1 IAGP ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, maternally transmitted ClinVar PMID:7804130 PMID:8254046 PMID:9506761 PMID:31965079 PMID:32906214 NCBI chr MT:3,230...3,304
Ensembl chr MT:3,230...3,304 		JBrowse link
G MT2A metallothionein 2A IAGP associated with Atherosclerosis; DNA:snp:promoter:g.-209A>G (human)
DNA:missense mutation:cds:p.K51R (rs8052394) (human)		 RGD PMID:16518702 PMID:18349110 RGD:6483843, RGD:6483853 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
no_association		 IAGP DNA:transition:cds:g.677C>T (human)
DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human)		 RGD PMID:21186995 PMID:19996639 PMID:16828193 RGD:6893476, RGD:6893653, RGD:6893657 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MTNR1A melatonin receptor 1A ISO mRNA:increased expression:pancreas RGD PMID:16441550 RGD:2301037 NCBI chr 4:186,533,655...186,555,567
Ensembl chr 4:186,526,792...186,555,567 		JBrowse link
G MTNR1B melatonin receptor 1B susceptibility IEP
EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to		 CTD
OMIM
ClinVar
RGD		 PMID:19060907 PMID:19060908 PMID:19060909 PMID:22286214 PMID:26551672 More... RGD:9588652 NCBI chr11:92,969,651...92,984,960
Ensembl chr11:92,969,651...92,985,066 		JBrowse link
G MTOR mechanistic target of rapamycin kinase susceptibility IAGP
ISO		 DNA:SNP: :rs7212142(human)
mRNA,protein:increased expression:hippocampus		 RGD PMID:28536139 PMID:23165862 RGD:13506787, RGD:13506788 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21818837 RGD:7207079 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase IEP protein:increased expression:serum
protein:decreased expression:adipose tissue		 RGD PMID:18410550 PMID:16234302 RGD:2311099, RGD:2311119 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NCCRP1 NCCRP1, F-box associated domain containing IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,196,964...39,201,884
Ensembl chr19:39,196,964...39,201,884 		JBrowse link
G NCOA6 nuclear receptor coactivator 6 ISO mRNA:decreased expression:pancreatic islet (rat) RGD PMID:16738321 RGD:9590126 NCBI chr20:34,714,774...34,825,651
Ensembl chr20:34,689,097...34,825,651 		JBrowse link
G NEUROD1 neuronal differentiation 1 no_association
onset		 IAGP
EXP		 DNA:missense mutation: :p.E110K (human
DNA:missense mutation: :p.S159P (human)
DNA:missense mutation, nonsense mutation (human)
associated with Obesity;DNA:missense mutation: :p.H241Q (human)
DNA:polymorphism: :p.A45T (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: NEUROD1-related condition		 ClinVar
CTD
OMIM
RGD		 PMID:10545951 PMID:16123366 PMID:25741868 PMID:28492532 PMID:28664602 More... RGD:2313488, RGD:2313480, RGD:2313489, RGD:2313478, RGD:2313486, RGD:2313482 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827 		JBrowse link
G NEUROG3 neurogenin 3 IAGP RGD PMID:17146417 RGD:2313775 NCBI chr10:69,571,485...69,573,422
Ensembl chr10:69,571,698...69,573,422 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:23954466 RGD:10412692 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17107852 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIB NFKB inhibitor beta IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893 		JBrowse link
G NKX6-1 NK6 homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G NOG noggin ISO mRNA, protein:increased expression:aorta RGD PMID:21193740 RGD:10430114 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:16323284 RGD:1581689 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 susceptibility IAGP
ISO
EXP		 DNA:insertion/deletion, repeat:promoter (human)
protein:increased expression:retina
protein:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16959961 PMID:19395279 PMID:18773271 PMID:21963495 RGD:2312484, RGD:2313220, RGD:5508747 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12716763 PMID:16959961 PMID:18356581 RGD:2292097 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOTCH2 notch receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18372903 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G NPPA natriuretic peptide A ISO RGD PMID:19675071 RGD:2313586 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B ISO
IEP		 protein:increased expression:plasma
protein:increased expression:serum		 RGD PMID:18192848 PMID:22037102 RGD:2293330, RGD:5685645 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NPY neuropeptide Y IAGP DNA:missense mutation:cds:p.L7P (human) RGD PMID:15926114 RGD:1580183 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 IAGP DNA:polymorphisms: :multiple RGD PMID:18781616 RGD:2311604 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 treatment ISO RGD PMID:23637135 RGD:10448992 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 IAGP RGD PMID:20939869 RGD:13506790 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 IEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:28871240 RGD:401850555 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:17292727 RGD:4892117 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NUCB2 nucleobindin 2 IEP
ISO		 mRNA:decreased expression:islet of Langerhans:
protein:decreased expression:pancreas:		 RGD PMID:22108805 PMID:20032201 RGD:9831161, RGD:9831177 NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 PMID:33812996 NCBI chr 6:117,675,469...117,710,727
Ensembl chr 6:117,675,469...117,710,727 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase IEP
EXP		 protein:increased expression:pancreatic islet, mitochondrion
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22652274 PMID:12003641 RGD:2317133 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO mRNA, protein:decreased expression, decreased activity:pancreatic islets (rat) RGD PMID:20460097 RGD:2326185 NCBI chr 5:41,730,065...41,870,425
Ensembl chr 5:41,730,065...41,870,425 		JBrowse link
G P2RY12 purinergic receptor P2Y12 IMP RGD PMID:15483100 RGD:6480536 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,385,629...39,391,106
Ensembl chr19:39,385,629...39,391,154 		JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,125,786...39,182,816
Ensembl chr19:39,125,770...39,182,816 		JBrowse link
G PAM peptidylglycine alpha-amidating monooxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:24464100 PMID:30054598 NCBI chr 5:102,754,783...103,031,105
Ensembl chr 5:102,753,981...103,029,730 		JBrowse link
G PAPPA pappalysin 1 IEP protein:decreased expression:serum RGD PMID:17728480 RGD:2313776 NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321 		JBrowse link
G PARL presenilin associated rhomboid like onset IAGP
IEP		 DNA:missense mutation:cds:p.L262V (human)
mRNA:decreased expression:vastus lateralis (human)		 RGD PMID:19185381 PMID:20444421 RGD:12880445, RGD:12902628 NCBI chr 3:183,826,489...183,884,880
Ensembl chr 3:183,829,271...183,884,933 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 IEP RGD PMID:15895395 RGD:11075068 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PAX4 paired box 4 onset IAGP
EXP		 DNA:mutation: :p.R121W (human)
DNA:polymorphism, mutations: :p.R192H, p.R164W, IVS7-1G>A (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset | ClinVar Annotator: match by term: Type II diabetes mellitus		 ClinVar
CTD
OMIM
RGD		 PMID:9536098 PMID:11723072 PMID:15596543 PMID:16423628 PMID:17576681 More... RGD:2311635, RGD:2311632 NCBI chr 7:127,610,292...127,618,142
Ensembl chr 7:127,610,292...127,618,142 		JBrowse link
G PAX6 paired box 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PC pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 no_association ISO
IAGP		 DNA:SNPs (human)
DNA:polymorphism:232C>G
DNA:polymorphism:promoter:C>G		 RGD PMID:17242918 PMID:18443203 PMID:19070910 PMID:16978381 PMID:16620271 RGD:2311643, RGD:2311640, RGD:2311639, RGD:1601239, RGD:1601241 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 no_association IAGP
ISO		 DNA:missense mutations:cds:p.R53Q, p.Q638E (human)
protein:increased expression:pancreatic alpha cell (mouse)
protein:decreased expression:pancreatic islet (mouse)
protein:altered expression:pancreatic islet (rat)		 RGD PMID:8666140 PMID:17630003 PMID:18941442 PMID:18448419 PMID:12475375 RGD:2308935, RGD:2308898, RGD:2308930, RGD:2308932, RGD:2298715 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 IAGP
EXP		 DNA:repeats:intron:IVS2CA (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16123366 PMID:7698505 RGD:2308936 NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578 		JBrowse link
G PDCD1 programmed cell death 1 ISO protein:increased expression:kidney RGD PMID:23219834 RGD:7248672 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 no_association ISO
IAGP
IEP
EXP		 protein:decreased expression:pancreas (rat)
DNA:insertion, polymorphism:cds:InsCCG243, Q59L, D76N (human)
mRNA:increased expression:pancreatic islet (human)
protein:increased expression:pancreatic duct (mouse)
DNA:polymorphism:cds:D76N (human)
DNA:deletion:exon 2 (mouse)
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar
CTD
OMIM
RGD		 PMID:10545530 PMID:10545531 PMID:10720084 PMID:11022198 PMID:11270685 More... RGD:2311219, RGD:2311307, RGD:2311305, RGD:2311306, RGD:2311221, RGD:2311308, RGD:2311217 NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:bone marrow stem cell (mouse) RGD PMID:21984919 RGD:6771358 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PEPD peptidase D EXP CTD Direct Evidence: marker/mechanism CTD PMID:22158537 NCBI chr19:33,386,950...33,521,791
Ensembl chr19:33,386,950...33,521,823 		JBrowse link
G PHOX2A paired like homeobox 2A ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr11:72,239,077...72,244,176
Ensembl chr11:72,239,077...72,245,664 		JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha IEP mRNA:decreased expression:Islets of Langerhans RGD PMID:21127054 RGD:7243008 NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986 		JBrowse link
G PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma susceptibility IAGP DNA:SNP:cds:437C>T(human) RGD PMID:17991425 RGD:13506796 NCBI chr12:18,242,961...18,726,817
Ensembl chr12:18,242,961...18,648,416 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta treatment IEP RGD PMID:11812753 RGD:13506799 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:31626838 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 susceptibility ISO
IAGP		 protein:increased phosphorylation:retina (rat)
DNA:polymorphism: :		 RGD PMID:18443201 PMID:14551916 RGD:4108490, RGD:11067972 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PKLR pyruvate kinase L/R susceptibility
no_association		 IAGP DNA:SNPs:introns,exons:
DNA:SNP: :rs3020781(human)		 RGD PMID:12196482 PMID:19111066 RGD:13506801, RGD:13506802 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438 		JBrowse link
G PLA2G7 phospholipase A2 group VII IDA RGD PMID:22399516 RGD:6482782 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
G PLAT plasminogen activator, tissue type ISO
IDA
IEP		 mRNA:decreased expression:kidney
associated with Obesity
protein:decreased expression:plasma (rat)		 RGD PMID:14693179 PMID:15901895 PMID:16724515 PMID:18235054 PMID:16038272 More... RGD:2311675, RGD:2311673, RGD:2311670, RGD:2311665, RGD:2311672, RGD:1598920 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor onset IEP protein:increased expression:plasma RGD PMID:22050462 RGD:6483792 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PLD3 phospholipase D family member 3 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:40,348,695...40,378,485
Ensembl chr19:40,348,456...40,389,472 		JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr10:122,374,708...122,442,600
Ensembl chr10:122,374,696...122,432,354 		JBrowse link
G PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,412,669...39,428,415
Ensembl chr19:39,412,669...39,428,415 		JBrowse link
G PLN phospholamban ISO mRNA:decreased expression:heart left ventricle RGD PMID:22621761 RGD:7327183 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 IAGP DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:31377187 RGD:14981594 NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488 		JBrowse link
G POMC proopiomelanocortin ISO associated with alcohol use disorder RGD PMID:33057655 RGD:407431647 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PON1 paraoxonase 1 severity
no_association		 IAGP
IEP		 DNA:polymorphism: :p.Q192R (human)
protein:increased expression:serum
protein:decreased expression:serum
associated with Diabetic Retinopathy;DNA:missense mutations:cds:p.L55M, p.Q192R (human)		 RGD PMID:18290860 PMID:19328014 PMID:17949258 PMID:10677395 PMID:9591753 RGD:2313269, RGD:2307252, RGD:2313270, RGD:8547560, RGD:8547663 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G PON2 paraoxonase 2 IAGP DNA:missense mutation:cds:p.S311C (human)
associated with Diabetic Retinopathy;DNA:missense mutation:cds:p.C310S (human)		 RGD PMID:18776646 PMID:10677395 RGD:2313490, RGD:8547560 NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:17317762 PMID:31626838 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta IAGP
ISS		 DNA:SNPs
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 MouseDO
RGD		 PMID:16804087 RGD:1625186 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma susceptibility
no_association		 IMP
ISO
IAGP
EXP		 DNA:polymorphism: :p.P12A (human)
DNA:snp:cds:p.P12A (human)
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigricans and Hypertension
ClinVar Annotator: match by term: Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigricans and Hypertension | ClinVar Annotator: match by term: Type 2 diabetes mellitus		 OMIM
CTD
ClinVar
RGD		 PMID:9467001 PMID:9792554 PMID:10381354 PMID:10523018 PMID:10690291 More... RGD:2301861, RGD:2301846, RGD:2301851, RGD:8552822 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment
susceptibility
no_association		 IAGP
ISO
IEP
EXP		 DNA:polymorphism:exon:p.G482S (human)
DNA:hypermethylation:promoter:g.-383 (human)
protein:decreased expression:vastus lateralis (human)
DNA:snps:intron:IVS3+52T>G, IVS3+21963A>G (rs2946385, rs4235308) (human)
DNA:polymorphism:exon:p.G482S (human, Pima Indians)
protein:decreased expression:dorsal root ganglia
mRNA:decreased expression:soleus muscle:type I muscle fiber (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15592662 PMID:17317762 PMID:18270681 PMID:23251491 PMID:23250358 More... RGD:2311391, RGD:7241849, RGD:7241851, RGD:7242009, RGD:7242032, RGD:7242043, RGD:7242067, RGD:7242175, RGD:10059689 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPARGC1B PPARG coactivator 1 beta no_association IAGP DNA:polymorphism:exon:102605C>A RGD PMID:16759305 RGD:1642500 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022 		JBrowse link
G PPP1R3A protein phosphatase 1 regulatory subunit 3A no_association
onset		 IMP
IAGP
EXP
ISS		 DNA:missense mutation:cds:p.D905Y (human)
DNA:missense mutation::p.D905Y (human)
DNA:missense mutations, polymorphisms:CDS, 3' UTR:p.R883S, p.D905Y (human)
DNA:missense mutation: :p.D905Y (human)
DNA:insertion/deletion
ClinVar Annotator: match by term: Type 2 diabetes mellitus
ClinVar Annotator: match by term: Insulin resistance, severe, digenic
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 OMIM
ClinVar
CTD
MouseDO
RGD		 PMID:7581368 PMID:12118251 PMID:25741868 PMID:11793847 PMID:10389856 More... RGD:2311560, RGD:2311532, RGD:2311531, RGD:2311515, RGD:2311405, RGD:2311596, RGD:2311552 NCBI chr 7:113,876,777...113,919,009
Ensembl chr 7:113,876,777...114,075,920 		JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO mRNA:increased expression:liver, quadriceps, epididymal fat pad (rat) RGD PMID:22087313 RGD:8693665 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:20054491 RGD:2316808 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 susceptibility IAGP DNA:SNPs RGD PMID:16567511 RGD:1625266 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRKCB protein kinase C beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:15531508 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRKCE protein kinase C epsilon ISO mRNA,protein:decreased expression:liver: RGD PMID:26398746 RGD:13506804 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PRKCI protein kinase C iota ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,424...170,305,977 		JBrowse link
G PRKCZ protein kinase C zeta ISO mRNA,protein:decreased expression:liver,pancreas: RGD PMID:26398746 RGD:13506804 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO protein:decreased expression:cerebral cortex (rat) RGD PMID:28573460 RGD:13432564 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PROX1 prospero homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20081858 NCBI chr 1:213,983,151...214,041,510
Ensembl chr 1:213,983,181...214,041,510 		JBrowse link
G PRX periaxin IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:40,393,764...40,414,789
Ensembl chr19:40,393,766...40,414,793 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764 		JBrowse link
G PSMD6 proteasome 26S subunit, non-ATPase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22158537 NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010 		JBrowse link
G PTF1A pancreas associated transcription factor 1a IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar NCBI chr10:23,192,312...23,194,245
Ensembl chr10:23,192,312...23,194,245 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO protein:increased expression:urine RGD PMID:16384826 RGD:1642580 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G PTGIS prostaglandin I2 synthase IEP protein:decreased expression:hypodermis (human) RGD PMID:24225501 RGD:401901153 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18706904 RGD:2300222 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH parathyroid hormone IAGP DNA:snp:exon:g.350C>A rs6256 (human) RGD PMID:22777106 RGD:7242744 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 susceptibility
no_association		 IAGP
EXP		 CTD Direct Evidence: marker/mechanism
DNA:missense mutation:CDS:p.P387L (human)		 OMIM
CTD
RGD		 PMID:15715684 PMID:11756316 RGD:401965404, RGD:401965405 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D susceptibility IAGP associated with Environmental Illness; DNA:SNP:intron: (rs16927668) (Human) RGD PMID:27281273 RGD:401850598 NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 ISO protein:increased expression:multiple: RGD PMID:30873215 RGD:15036825 NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 IEP mRNA:splice variant: heart (human) RGD PMID:27239029 RGD:329845874 NCBI chr22:35,738,736...36,028,824
Ensembl chr22:35,738,736...36,028,824 		JBrowse link
G RBP4 retinol binding protein 4 susceptibility
disease_progression
severity		 IAGP
IEP		 DNA:polymorphism
protein:increased expression:serum
protein:increased expression:blood plasma (human)
mRNA:increased expression:epicardial fat (human)
protein:increased expression:blood serum (human)
associated with arteriosclerosis and chronic kidney disease;protein:increased expression:blood plasma (human)
DNA:SNP:promoter:-803G>A (human)		 RGD PMID:17174134 PMID:19506831 PMID:24647386 PMID:21645024 PMID:20058618 More... RGD:1601615, RGD:2311651, RGD:329845577, RGD:329845584, RGD:329845844, RGD:329845851, RGD:329845855, RGD:329845878, RGD:329849119 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:29924900 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G RBPJL recombination signal binding protein for immunoglobulin kappa J region like IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar NCBI chr20:45,306,840...45,317,824
Ensembl chr20:45,306,840...45,317,824 		JBrowse link
G REG3A regenerating family member 3 alpha ISO mRNA:increased expression:islet of Langerhans (rat) RGD PMID:24587207 RGD:9831427 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753 		JBrowse link
G RETN resistin no_association
susceptibility		 IEP
IAGP
EXP		 protein:increased expression:serum
DNA:polymorphism: :299G>A (human)
DNA:SNP:promoter:-420G>C (rs1862513) (human)
DNA:SNPs:promoter:-394C>G, -420G>C (rs1862513) (human)
DNA:SNP:3' utr:*62A>G (human)
protein:decreased expression:serum
ClinVar Annotator: match by term: HYPERTENSION, INSULIN RESISTANCE-RELATED, SUSCEPTIBILITY TO
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:11558907 PMID:12629116 PMID:19269054 PMID:19177195 PMID:19738363 More... RGD:2313497, RGD:2313498, RGD:2313494, RGD:2313495, RGD:1624968, RGD:7207163 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455 		JBrowse link
G RINL Ras and Rab interactor like IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,867,830...38,878,275
Ensembl chr19:38,867,830...38,878,275 		JBrowse link
G RNF6 ring finger protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314 		JBrowse link
G RPS16 ribosomal protein S16 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,433,137...39,435,949
Ensembl chr19:39,433,137...39,435,949 		JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator IAGP associated with Obesity;DNA:polymorphism:intron:4681C>T (human)
DNA:repeat:intron (human)		 RGD PMID:15161552 PMID:10024077 RGD:2311704, RGD:2311705 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535 		JBrowse link
G S100A6 S100 calcium binding protein A6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244 		JBrowse link
G SAMD4B sterile alpha motif domain containing 4B IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,342,421...39,390,764
Ensembl chr19:39,342,421...39,385,710 		JBrowse link
G SARS2 seryl-tRNA synthetase 2, mitochondrial IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,915,266...38,930,763
Ensembl chr19:38,915,266...38,930,763 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO mRNA:increased expression:heart ventricle RGD PMID:22581745 RGD:6484255 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449 		JBrowse link
G SCTR secretin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr 2:119,439,843...119,524,483
Ensembl chr 2:119,439,843...119,525,301 		JBrowse link
G SDC2 syndecan 2 IEP protein:increased expression:kidney RGD PMID:14976204 RGD:2311706 NCBI chr 8:96,493,813...96,611,790
Ensembl chr 8:96,493,813...96,611,790 		JBrowse link
G SDC4 syndecan 4 ISO
IAGP		 mRNA:increased expression:kidney
ClinVar Annotator: match by term: Type 2 diabetes mellitus		 ClinVar
RGD		 PMID:14633120 RGD:2311707 NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,424 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 susceptibility ISO DNA:deletion:exons, introns:g.3_910del (rat) RGD PMID:27463508 RGD:11528530 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B ISS OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036 MouseDO NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151 		JBrowse link
G SELENOV selenoprotein V IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,515,113...39,520,686
Ensembl chr19:39,515,139...39,520,675 		JBrowse link
G SELL selectin L no_association IAGP RGD PMID:22119815 RGD:7175303 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SELP selectin P IEP protein:increased expression:plasma RGD PMID:17598012 RGD:2312303 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SERPINA12 serpin family A member 12 treatment ISO RGD PMID:16030142 RGD:1547845 NCBI chr14:94,487,279...94,517,844
Ensembl chr14:94,487,274...94,517,844 		JBrowse link
G SERPINC1 serpin family C member 1 IEP protein:increased activity:plasma (human) RGD PMID:7974333 RGD:2312416 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
G SERPINE1 serpin family E member 1 no_association
treatment		 IAGP
ISO
IEP		 DNA:polymorphism:
mRNA:increased expression:kidney
protein:decreased expression:plasma (human)		 RGD PMID:16855181 PMID:19706694 PMID:8236167 PMID:14614217 RGD:1624959, RGD:2316116, RGD:8547723, RGD:2312394 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPINF1 serpin family F member 1 treatment
severity		 IEP
ISO
IDA		 protein:increased expression:serum
protein:increased expression:plasma (rat)
human protein in a rat model		 RGD PMID:18715664 PMID:17653050 PMID:24530621 PMID:24530621 RGD:2312340, RGD:8554888, RGD:8655541, RGD:8655541 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SFRP4 secreted frizzled related protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23140642 NCBI chr 7:37,905,932...37,916,817
Ensembl chr 7:37,905,932...38,025,695 		JBrowse link
G SGCG sarcoglycan gamma susceptibility IAGP DNA:SNP: : rs9552911(human) RGD PMID:28123479 RGD:13605620 NCBI chr13:23,160,508...23,325,162
Ensembl chr13:23,180,979...23,325,162 		JBrowse link
G SHBG sex hormone binding globulin susceptibility IAGP
EXP		 DNA, protein:SNPs, decreased expression:rs6257, rs6259, plasma (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21982312 PMID:19657112 RGD:2313782 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382 		JBrowse link
G SIRT1 sirtuin 1 treatment ISO
EXP		 associated with Obesity
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23834033 PMID:18046409 PMID:19549853 RGD:9585769, RGD:9585997 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SIRT2 sirtuin 2 IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G SIRT3 sirtuin 3 IEP mRNA:decreased expression:pancreatic islet RGD PMID:23397292 RGD:9586042 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SLC1A2 solute carrier family 1 member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30718926 NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 6:160,348,378...160,452,577
Ensembl chr 6:160,348,378...160,452,577 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 no_association IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9589670 PMID:18613291 PMID:9789717 PMID:7516306 RGD:2312306, RGD:2312290, RGD:2312289 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 susceptibility IAGP
EXP
ISS		 DNA:SNPs (human)
DNA:point mutation:exon:p.V197I (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Type 2 diabetes mellitus
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 OMIM
CTD
ClinVar
MouseDO
RGD		 PMID:8027028 PMID:8063045 PMID:9354798 PMID:11810292 PMID:13480676 More... RGD:2312359, RGD:1624252 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 IEP protein:decreased expression:granulocyte, lymphocyte, monocyte RGD PMID:19110659 RGD:2313602 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO
IAGP
EXP
ISS		 DNA:point mutation:exon:p.V383I (human)
ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 ClinVar
CTD
MouseDO
RGD		 PMID:1397719 PMID:1918382 PMID:7814014 PMID:11947963 PMID:17107852 More... RGD:2313625, RGD:1625188 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC30A8 solute carrier family 30 member 8 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Type 2 diabetes mellitus
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to		 ClinVar
CTD
OMIM		 PMID:17293876 PMID:17460697 PMID:17463246 PMID:17463248 PMID:17463249 More... NCBI chr 8:116,950,217...117,176,714
Ensembl chr 8:116,950,273...117,176,714 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO mRNA, protein:decreased expression:heart RGD PMID:22009485 RGD:6771327 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981 		JBrowse link
G SLPI secretory leukocyte peptidase inhibitor IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564 		JBrowse link
G SMAD4 SMAD family member 4 treatment ISO RGD PMID:25017203 RGD:12880049 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD5 SMAD family member 5 EXP CTD Direct Evidence: therapeutic CTD PMID:20079400 NCBI chr 5:136,132,845...136,182,733
Ensembl chr 5:136,132,845...136,188,747 		JBrowse link
G SMC1A structural maintenance of chromosomes 1A ISO mRNA:increased expression:testis: RGD PMID:33775663 RGD:155631260 NCBI chr  X:53,374,149...53,422,728
Ensembl chr  X:53,374,149...53,422,728 		JBrowse link
G SMIM43 small integral membrane protein 43 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 4:121,758,930...121,765,433
Ensembl chr 4:121,758,881...121,765,427 		JBrowse link
G SNAP25 synaptosome associated protein 25 EXP
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036		 CTD
MouseDO		 PMID:16123366 NCBI chr20:10,218,830...10,307,418
Ensembl chr20:10,172,395...10,308,258 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 ISO mRNA:increased expression:peritoneal macrophage (mouse) RGD PMID:26606676 RGD:126925207 NCBI chr 1:179,293,797...179,358,680
Ensembl chr 1:179,293,714...179,358,680 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 treatment ISO
IEP		 mRNA:increased expression:skeletal muscle RGD PMID:17513737 PMID:15331532 PMID:29110587 RGD:2313788, RGD:2313790, RGD:13506806 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 IEP
IAGP
ISO
EXP		 protein:decreased expression:erythrocyte
DNA:polymorphism:intron:IVS3+35A>C (rs2234694) (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15531508 PMID:19317795 PMID:18423055 PMID:16005359 RGD:2312363, RGD:2312364, RGD:1581216 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 IAGP
EXP		 DNA:polymorphism: :p.A16V (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15531508 PMID:18423055 RGD:2312364 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOD3 superoxide dismutase 3 IDA RGD PMID:15990193 RGD:1581225 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 IAGP DNA:SNP: :p.T228A (human) RGD PMID:11532984 RGD:1642744 NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414 		JBrowse link
G SPHK1 sphingosine kinase 1 IMP RGD PMID:17265031 RGD:2311390 NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO
IDA		 protein:increased tyrosine phosphorylation:platelets RGD PMID:19230846 PMID:15542065 RGD:2307340, RGD:1601373 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO mRNA:increased expression:adrenal gland (rat) RGD PMID:17884440 RGD:4891894 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 susceptibility IAGP
ISO		 DNA:SNPs
mRNA:increased expression:liver		 RGD PMID:18692268 PMID:19357831 RGD:2308809, RGD:2308802 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 IDA RGD PMID:15644403 RGD:1581419 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21874001 NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,325...187,078,553 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO mRNA:decreased expression:testis, Leydig cell (rat) RGD PMID:18481435 RGD:4889107 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 IDA protein:increased tyrosine phosphorylation:skeletal muscle RGD PMID:23043161 RGD:8694321 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,445,582...39,476,670
Ensembl chr19:39,436,156...39,476,670 		JBrowse link
G SYCN syncollin IAGP ClinVar Annotator: match by term: Type 2 diabetes mellitus ClinVar PMID:28492532 NCBI chr19:39,202,825...39,204,263
Ensembl chr19:39,202,825...39,204,263 		JBrowse link
G