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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:gas gangrene
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Accession:DOID:9159 term browser browse the term
Definition:A commensal bacterial infectious disease that results in infection, located in muscle tissue, has_material_basis_in Clostridium perfringens, which produce gas that becomes trapped in the infected tissue. Gas gangrene usually develops after injuries or surgery. The infection has symptom large blisters, has symptom pain in the infected area, has symptom myonecrosis, has symptom gas production, and has symptom sepsis. (DO)
Synonyms:exact_synonym: gas bacillus infection;   gas gangrenes;   myonecrosis
 primary_id: MESH:D005738
 xref: EFO:0007279;   ICD10CM:A48.0;   ICD9CM:040.0

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gas gangrene term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin ISO protein:decreased expression:blood serum (human) RGD PMID:9142022 RGD:329333022 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15388
    disease by infectious agent 2092
      Bacterial Infections and Mycoses 1023
        bacterial infectious disease 785
          commensal bacterial infectious disease 65
            gas gangrene 1
Path 2
Term Annotations click to browse term
  disease 15388
    disease of anatomical entity 15074
      nervous system disease 13213
        peripheral nervous system disease 4165
          neuropathy 3976
            neuromuscular disease 3144
              muscular disease 2173
                muscle tissue disease 1312
                  gas gangrene 1
paths to the root