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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:gas gangrene
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Accession:DOID:9159 term browser browse the term
Definition:A commensal bacterial infectious disease that results in infection, located in muscle tissue, has_material_basis_in Clostridium perfringens, which produce gas that becomes trapped in the infected tissue. Gas gangrene usually develops after injuries or surgery. The infection has symptom large blisters, has symptom pain in the infected area, has symptom myonecrosis, has symptom gas production, and has symptom sepsis. (DO)
Synonyms:exact_synonym: gas bacillus infection;   gas gangrenes;   myonecrosis
 primary_id: MESH:D005738
 xref: EFO:0007279;   ICD10CM:A48.0;   ICD9CM:040.0

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gas gangrene term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin ISO protein:decreased expression:blood serum (human) RGD PMID:9142022 RGD:329333022 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 10941
    disease by infectious agent 1817
      Bacterial Infections and Mycoses 716
        bacterial infectious disease 621
          commensal bacterial infectious disease 66
            gas gangrene 1
Path 2
Term Annotations click to browse term
  disease 10941
    disease of anatomical entity 10388
      nervous system disease 7508
        peripheral nervous system disease 2132
          neuropathy 1947
            neuromuscular disease 1410
              muscular disease 1094
                muscle tissue disease 694
                  gas gangrene 1
paths to the root