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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:lung metastasis
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Accession:DOID:9009121 term browser browse the term
Definition:Transfer of a neoplasm from its primary site to the lung. Because a lung metastasis develops from some underlying cancer elsewhere in the body, it is called a “secondary” malignancy
Synonyms:xref: PMID:26265454
For additional species annotation, visit the Alliance of Genome Resources.


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lung metastasis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap5 Rho GTPase activating protein 5 ISO associated with Mammary Neoplasms, Experimental RGD PMID:20860838 RGD:126848767 NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
JBrowse link
G Fasn fatty acid synthase ISO associated with head and neck squamous cell carcinoma RGD PMID:20604875 RGD:126790467 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17126
    disease of cellular proliferation 6943
      Neoplastic Processes 634
        Neoplasm Metastasis 421
          lung metastasis 2
Path 2
Term Annotations click to browse term
  disease 17126
    disease of anatomical entity 16474
      respiratory system disease 2863
        thoracic disease 1806
          Thoracic Neoplasms 1262
            Respiratory Tract Neoplasms 817
              Lung Neoplasms 799
                lung cancer 524
                  lung metastasis 2
paths to the root