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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Brain Concussion
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Accession:DOID:9008967 term browser browse the term
Definition:A nonspecific term used to describe transient alterations or loss of consciousness following closed head injuries. The duration of UNCONSCIOUSNESS generally lasts a few seconds, but may persist for several hours. Concussions may be classified as mild, intermediate, and severe. Prolonged periods of unconsciousness (often defined as greater than 6 hours in duration) may be referred to as post-traumatic coma (COMA, POST-HEAD INJURY). (From Rowland, Merritt's Textbook of Neurology, 9th ed, p418)
Synonyms:exact_synonym: Brain Concussions;   Cerebral Concussion;   Cerebral Concussions;   Commotio Cerebri;   Intermediate Concussion;   Intermediate Concussions;   Mild Concussion;   Mild Concussions;   Mild Traumatic Brain Injury;   Severe Concussion;   Severe Concussions
 primary_id: MESH:D001924;   RDO:0005052
 xref: EFO:0011023


show annotations for term's descendants           Sort by:
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:26448536 RGD:13506960 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:26448536 RGD:13506960 NCBI chr33:18,369,362...18,414,465
Ensembl chr33:18,372,865...18,412,277 		JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:26448536 RGD:13506960
G IL6 interleukin 6 treatment ISO RGD PMID:27113205 RGD:11062140 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17773
    Wounds and Injuries 949
      Nonpenetrating Wounds 21
        Closed Head Injuries 10
          Brain Concussion 4
            Contrecoup Injury 0
            Post-Concussion Syndrome 0
Path 2
Term Annotations click to browse term
  disease 17773
    disease of anatomical entity 15145
      nervous system disease 13207
        Nervous System Trauma 582
          Craniocerebral Trauma 353
            Brain Injuries 279
              traumatic brain injury 55
                Brain Concussion 4
                  Contrecoup Injury 0
                  Post-Concussion Syndrome 0
paths to the root