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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Binge-Eating Disorder
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Accession:DOID:9008953 term browser browse the term
Definition:A disorder associated with three or more of the following: eating until feeling uncomfortably full; eating large amounts of food when not physically hungry; eating much more rapidly than normal; eating alone due to embarrassment; feeling of disgust, DEPRESSION, or guilt after overeating. Criteria includes occurrence on average, at least 2 days a week for 6 months. The binge eating is not associated with the regular use of inappropriate compensatory behavior (i.e. purging, excessive exercise, etc.) and does not co-occur exclusively with BULIMIA NERVOSA or ANOREXIA NERVOSA. (From DSM-IV, 1994)
Synonyms:exact_synonym: Binge-Eating Disorders
 primary_id: MESH:D056912;   RDO:0007767
For additional species annotation, visit the Alliance of Genome Resources.


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Binge-Eating Disorder term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNR1 cannabinoid receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23072421 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,359
JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:28821448 RGD:13506951 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:28821448 RGD:13506951 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:28821448 RGD:13506951 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G MC4R melanocortin 4 receptor IAGP RGD PMID:12646666 RGD:1600752 NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18837
    disease of anatomical entity 17323
      nervous system disease 13417
        central nervous system disease 11457
          brain disease 10643
            disease of mental health 8151
              eating disorder 15
                Binge-Eating Disorder 5
Path 2
Term Annotations click to browse term
  disease 18837
    disease of anatomical entity 17323
      nervous system disease 13417
        central nervous system disease 11457
          brain disease 10643
            disease of mental health 8151
              developmental disorder of mental health 4718
                specific developmental disorder 2763
                  eating disorder 15
                    Binge-Eating Disorder 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.